Naloxone Hydrochloride Injection USP 1mL, 10 Pack
Naloxone Hydrochloride Injection, USP, is a solution containing naloxone hydrochloride, a competitive antagonist of opioid receptors. Clinically, Naloxone prevents or reverses the effects of opioids including respiratory depression, sedation and hypotension. In the workplace, this material should be considered potentially irritating to the eyes and respiratory tract, and a potent drug. Based on clinical use, possible target organs include the nervous system and cardiovascular system.
Naloxone Hydrochloride for Injection USP 1mL, are sold in single-dose vials by Hospira. It is a sterile, nonpyrogenic solution of naloxone hydrochloride in water for injection. Each milliliter (mL) contains 0.4 mg naloxone hydrochloride and sodium chloride to adjust tonicity in water for injection. May contain hydrochloric acid for pH adjustment; pH 4.0 (3.0 to 6.5).
Naloxone, an opioid antagonist, is a synthetic congener of oxymorphone. It differs from oxymorphone in that the methyl group on the nitrogen atom is replaced by an allyl group. Naloxone Hydrochloride, USP is chemically designed 17-Allyl-4.5a-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride (619H21N04-HCI), a white to slightly off-white powder soluble in alcohol; practically in soluble in ether and chloroform. It has a molecular weight of 363.84.
With 3 out of 4 prescription painkiller overdoses being caused by opioid use, getting this anti-overdose drug into the hands of first responders and bystanders (such as family, friends, community members, and other addicts themselves) is going to be a crucial step in reducing the number of overdose deaths related to opioid usage.
- Helps prevent opioid overdose deaths
- Quick and easy to use
- Sterile, nonpyrogenic solution
- Single dose vials
- Each milliliter (mL) contains 0.4 mg naloxone hydrochloride and sodium chloride
- This medication saves lives!
- Its safe, effective, and easy to use
- It works quickly
- Works for people of all ages, races, and backgrounds
- To offset the effects of opioid drug overdoses that have caused the user to have shallow breathing (or no breathing) and/or a loss of consciousness. This medication will help reverse the effects of overdoses caused by opioid drugs only, including:
- Oxycodone (Oxycontin)
- Hydrocodone (Vicodin)
- And other prescription pain medication
- This medication will not offset the effects of overdoses caused by other types of drugs, such as benzodiazepines, including Xanax, Klonopin and Valium, bath salts, cocaine, methamphetamine or alcohol.
Recommendations for Optimal Usage:
- Bystanders or first responders should administer this drug as soon as they notice that the individual has lost consciousness and is no longer responding or has very shallow breathing.
- After administering this medication rescue breaths should be administered while waiting for the drug to work its magic and reawaken the individual (which should occur within 5 minutes of administering the Naloxone).
- In addition to administering the Naloxone and giving rescue breaths (if needed) it is imperative that 911 be called. Once the individual awakens they will immediately start experiencing withdrawal symptoms. When the Naloxone wears off (after anywhere from 30-90 minutes) the overdose symptoms are likely to return and the individual could lose consciousness and stop breathing again.