Procainamide Injection Prefilled Syringes 100 mg/mL Luer-Jet 10 mL x 5/Pack
Procainamide Hydrochloride Injection is a fast-acting antiarrhythmic agent provided in a convenient Luer-Jet prefilled syringe, ensuring rapid response and precise dosing in urgent clinical situations. Each pack includes five 10 mL prefilled syringes (total 5000 mg procainamide per pack), perfectly suited for emergency departments, critical care, and hospital settings where reliability and sterility are paramount.
What Is Procainamide HCl Injection Used For?
Procainamide HCl Injection is indicated for:
- Treatment and prevention of life-threatening cardiac arrhythmias, including sustained ventricular tachycardia.
- Temporary control of arrhythmias during anesthesia, surgery, or myocardial infarction.
- Stabilizing acute ventricular arrhythmias when oral therapy is not possible or rapid intervention is required.
- As an alternative when other antiarrhythmic agents are contraindicated or ineffective.
Product Details & Features
- Active Ingredient: Procainamide Hydrochloride, 100 mg/mL
- Volume: 10 mL per prefilled syringe (1,000 mg per syringe)
- Packaging: 5 syringes per package (total 5,000 mg per pack)
- Administration Route: Intravenous (IV) use only
- Manufacturer: International Medication Systems (IMS)
- Sterile & Pyrogen-Free: Designed for rapid hospital or EMS administration
- Luer-Jet Prefilled Syringe: Reduces medication preparation time, ensures sterility, and delivers precise dosing instantly
- Latex-free, Single-Use Syringe
Key Features
- Rapid Onset: For immediate control of dangerous arrhythmias.
- Consistent Dosing: Prefilled syringes minimize dosing errors and maximize clinical efficiency.
- Sterile & Tamper-Evident: Enhances patient safety and infection control standards.
- Convenient Multipack: Ideal for high-use clinical environments.
Directions for Use
- Inspect the syringe and solution for particles or discoloration before use. Do not use if the solution appears cloudy, discolored, or if the packaging is damaged.
- Aseptic Technique: Always use proper aseptic technique when handling and administering injections.
- Connect the Luer-Jet syringe to a compatible IV access device.
- Administer IV Slowly: Inject directly into the intravenous line or catheter as directed by a physician.
- Monitor: Continuously monitor the patient’s ECG, blood pressure, and clinical status during administration.
Dosage
Adults:
- Initial IV Loading Dose: 20 mg/minute until arrhythmia is controlled, QRS complex widens by 50%, or a total of 17 mg/kg is administered.
- Maximum Single Dose: Do not exceed 1 gram in a single loading dose.
- Maintenance Dose: Continuous IV infusion of 1–4 mg/min as needed, titrated to clinical response.
Children:
- Initial Loading Dose: 3–6 mg/kg administered IV over 5–10 minutes, under continuous ECG monitoring.
- Maintenance: Individualized and physician-directed, based on clinical response.
Important: Dosage must be individualized and titrated to therapeutic response. Always verify recommended dosages with current clinical guidelines and facility protocols.
CDC Guidelines & Best Practices
-
Strict Aseptic Technique: Adhere to CDC clinical standards for injection safety and infection control.
- Never reuse syringes or needles.
- Use a new, sterile syringe and needle per patient.
- Monitor for Adverse Events: ECG and blood pressure should be continuously monitored throughout administration and recovery.
- Proper Staff Training: Only qualified healthcare professionals experienced in antiarrhythmic drug therapy should administer procainamide.
- Adverse Event Reporting: Report any medication errors or adverse events according to institutional and regulatory requirements.
Warnings
- Proarrhythmic Effect: Procainamide can induce or worsen certain arrhythmias—continuous ECG monitoring is required.
- Complete Heart Block: Contraindicated in patients with complete heart block in absence of a functioning artificial pacemaker.
- Hypersensitivity: Contraindicated in patients with known hypersensitivity to procainamide or related drugs (procainamide, procaine, etc.).
- Drug-Induced Lupus Erythematosus: Long-term use may result in a lupus-like syndrome.
- Blood Dyscrasias: Risk of agranulocytosis, neutropenia, and thrombocytopenia; perform regular blood count monitoring if prolonged use is anticipated.
- Hypotension: Rapid IV administration can cause severe hypotension; administer slowly and monitor hemodynamics.
- Renal or Hepatic Impairment: Adjust dosage accordingly and monitor closely.
Possible Side Effects
Common:
- Nausea, vomiting
- Abdominal pain
- Dizziness or lightheadedness
- Flushing
Serious:
- Severe hypotension
- Heart block or worsened arrhythmias
- Lupus-like symptoms (joint pain, fever, rash)
- Blood disorders (agranulocytosis, neutropenia)
- Allergic reactions: rash, itching, swelling, difficulty breathing (seek immediate medical attention)
Monitor patient closely during and after administration for any unexpected side effects or adverse reactions.
Procainamide HCl Injection 100 mg/mL Luer-Jet Prefilled Syringe 10 mL x 5/Pack by International Medication Systems: When every second counts, trust a rapid, reliable, and precise solution for acute cardiac arrhythmia management. For professional hospital and emergency use only.
Always consult a licensed healthcare provider for guidance. Use as directed.
International Medication Systems – Precise Care in Every Syringe.