{"title":"Amphastar Pharmaceuticals","description":"\u003ch2\u003eAmphastar Pharmaceuticals\u003c\/h2\u003e\n\u003ch3\u003eLeading Innovator in Injectable Medications, Respiratory Health, and Hospital-Grade Pharmaceutical Solutions\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAmphastar Pharmaceuticals\u003c\/strong\u003e is a trusted, FDA-approved leader in the development, manufacturing, and distribution of high-quality, affordable injectables, emergency medications, respiratory care solutions, and specialty pharmaceuticals. Recognized by healthcare professionals, hospital systems, pharmacies, and clinics nationwide, Amphastar delivers cutting-edge, reliable therapies to advance patient outcomes and raise the standard of care.\u003c\/p\u003e\n\u003ch3\u003eWhy Choose Amphastar Pharmaceuticals?\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eComprehensive Injectable Portfolio:\u003c\/strong\u003e Industry-leading range of \u003cstrong\u003einjectable medications\u003c\/strong\u003e, including critical care drugs, pain management injections, anti-infectives, hormone therapies, and emergency rescue treatments.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRespiratory Health Solutions:\u003c\/strong\u003e Proprietary, FDA-approved inhalations, nebulizer solutions, and nasal sprays for \u003cstrong\u003easthma, COPD, allergy relief, and acute respiratory distress\u003c\/strong\u003e—trusted for rapid, effective symptom control.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEmergency \u0026amp; Hospital Care:\u003c\/strong\u003e Preferred provider to hospitals and EMS for essential medications, such as \u003cstrong\u003eepinephrine, naloxone (opioid overdose reversal), glucagon, and sterile saline solutions\u003c\/strong\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFDA-Approved \u0026amp; cGMP Certified:\u003c\/strong\u003e All products are manufactured to strict FDA standards and Good Manufacturing Practices, ensuring \u003cstrong\u003epurity, potency, and patient safety\u003c\/strong\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInnovation \u0026amp; Affordability:\u003c\/strong\u003e Dedicated to making \u003cstrong\u003ecomplex generics and specialty drugs\u003c\/strong\u003e accessible and cost-effective for healthcare providers and patients alike.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReliable US-Based Supply Chain:\u003c\/strong\u003e Consistent, nationwide distribution guarantees product availability to hospitals, clinics, and pharmacies—when and where it matters most.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eAmphastar Pharmaceuticals: Top Health Solutions\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCritical Care \u0026amp; Emergency Medicines:\u003c\/strong\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eEpinephrine Injection\u003c\/strong\u003e for anaphylaxis\/allergic reactions\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNaloxone Injection\/Nasal Spray\u003c\/strong\u003e for opioid overdose rescue\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGlucagon Injection\u003c\/strong\u003e for severe hypoglycemia in diabetes\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSterile Saline \u0026amp; Electrolyte Solutions\u003c\/strong\u003e for IV hydration and resuscitation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRespiratory Therapies:\u003c\/strong\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAlbuterol Sulfate Inhalation Solution\u003c\/strong\u003e for asthma and COPD\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBudesonide Suspension\u003c\/strong\u003e for inhalation in pediatric and adult respiratory disease\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eDecongestant \u0026amp; Allergy Nasal Sprays\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePain Management Injections:\u003c\/strong\u003e\n\u003cul\u003e\n\u003cli\u003eHospital-grade local anesthetics and adjunct pain medications for surgery and trauma\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHormone Therapies:\u003c\/strong\u003e\n\u003cul\u003e\n\u003cli\u003eInjectable treatment for disorders such as hypogonadism and pituitary dysfunction\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnti-Infectives \u0026amp; Antibiotics:\u003c\/strong\u003e\n\u003cul\u003e\n\u003cli\u003eReady-to-use sterile anti-infective agents for hospital and clinic use\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eKey Benefits\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRapid Symptom Relief:\u003c\/strong\u003e Fast, potent action in acute and emergency situations—life-saving medications you can count on.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUS Manufactured \u0026amp; Distributed:\u003c\/strong\u003e Proudly supporting American hospitals and healthcare with consistent, on-time delivery.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDoctor-Recommended \u0026amp; Hospital-Preferred:\u003c\/strong\u003e Backed by clinical research, proven outcomes, and preferred status in formulary selections.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eComprehensive Support:\u003c\/strong\u003e Educational materials, clinical training, and responsive customer service for healthcare professionals.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eFrequently Asked Questions\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAre Amphastar products FDA approved?\u003c\/strong\u003e Yes—all Amphastar pharmaceuticals meet or exceed rigorous FDA and cGMP quality and safety standards.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho chooses Amphastar?\u003c\/strong\u003e Leading U.S. hospitals, emergency departments, physicians, pharmacists, outpatient clinics, and EMS agencies rely on Amphastar for critical injectables and respiratory medicines.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCan Amphastar medications be used for children and adults?\u003c\/strong\u003e Yes—many formulations are indicated for both pediatric and adult populations. Always follow healthcare provider instructions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat respiratory conditions does Amphastar treat?\u003c\/strong\u003e Asthma, COPD, bronchospasm, allergy symptoms, and acute respiratory distress.\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"EcDrQ pdMy8\"\u003e\u003cstrong\u003eChoose Amphastar Pharmaceuticals for industry-leading injectable medicines, advanced respiratory solutions, and emergency care products—trusted for quality, efficacy, and supply when lives are on the line. Elevate your healthcare delivery with Amphastar’s FDA-approved pharmaceutical excellence.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e","products":[{"product_id":"naloxone-injection-prefilled-syringe-opioid-antidote-2-ml","title":"Naloxone Prefilled Syringe for Injection 2mg Dose (Rx)","description":"\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003cstrong\u003eNaloxone prefilled syringe\u003c\/strong\u003e refers to a \u003cstrong\u003eready-to-use syringe that comes pre-loaded with naloxone solution\u003c\/strong\u003e, intended for quick administration during an \u003cstrong\u003eopioid overdose emergency\u003c\/strong\u003e. Naloxone itself is a \u003cstrong\u003emedication that rapidly reverses the effects of opioids\u003c\/strong\u003e (such as heroin, fentanyl, or prescription painkillers) by binding to opioid receptors and blocking or displacing the opioid molecules. This antidote can restore normal breathing in a person whose breathing has slowed or stopped due to an overdose.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cstrong\u003e\u003c\/strong\u003e\u003cstrong\u003eUses:\u003c\/strong\u003e\n\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eLife-Saving Opioid Overdose Treatment\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eCrucial for Fentanyl, Heroin, Prescription Painkiller Overdose\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eRestores Normal Breathing Until Emergency Help Arrives\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003ePrevents Fatalities and Severe Brain Injury\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eIntegral Part of Harm Reduction and Public Health Programs\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eWhen we say “prefilled syringe,” it means the syringe is \u003cstrong\u003ealready filled by the manufacturer with a specific dose of naloxone\u003c\/strong\u003e, so a rescuer doesn’t have to draw up the medication from a vial. It’s essentially \u003cem\u003enaloxone in an injectable form, packaged for immediate use\u003c\/em\u003e. Prefilled syringes are designed to make naloxone administration simpler and faster for both medical professionals and everyday people who might be responding to an overdose.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey features of a Naloxone Prefilled Syringe:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003ePre-Measured Dose:\u003c\/strong\u003e The syringe contains a set amount of naloxone, often a standard dose such as \u003cstrong\u003e2 mg in 2 mL\u003c\/strong\u003e or \u003cstrong\u003e1 mg in 1 mL\u003c\/strong\u003e of solution (concentrations can vary by product). Because the dose is pre-measured, the user doesn’t need to worry about calculating or measuring the medication in the moment – they simply use the syringe as instructed. This reduces the chance of dosing errors and saves valuable time when responding to an overdose.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eAdministration Routes:\u003c\/strong\u003e A naloxone prefilled syringe is typically intended for \u003cstrong\u003einjection\u003c\/strong\u003e into a muscle (intramuscular, e.g., into the outer thigh or shoulder) or under the skin (subcutaneous), though in hospital settings it can be given intravenously. In community overdose kits, the most common use of a prefilled naloxone syringe is \u003cstrong\u003eintramuscular injection\u003c\/strong\u003e. The syringe often comes with a needle or the kit includes a separate needle that you attach. To use it, you would remove safety caps, insert the needle into the person’s thigh (through clothing if necessary), and push the plunger to inject the medication. Naloxone usually works within 2-3 minutes to start reversing respiratory depression.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eIntranasal Use with Adapter:\u003c\/strong\u003e Some naloxone prefilled syringes are also used for \u003cstrong\u003eintranasal administration\u003c\/strong\u003e (through the nose) by adding a special atomizer tip. In many community programs, naloxone is supplied as a \u003cstrong\u003eprefilled syringe (typically 2 mg of naloxone in 2 mL)\u003c\/strong\u003e plus a \u003cstrong\u003emucosal atomization device\u003c\/strong\u003e that attaches to the syringe. In an overdose, the responder twists the atomizer onto the syringe, then sprays half the dose up one nostril and half up the other. The liquid is atomized into a fine mist that is absorbed through the nasal lining. This method allows bystanders to give naloxone \u003cstrong\u003ewithout using a needle\u003c\/strong\u003e. (Note: More recently, single-step nasal spray devices like Narcan® have become popular, but the prefilled syringe + atomizer is still used in many kits because it’s cost-effective and easy to assemble.)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eEase of Use in Emergencies:\u003c\/strong\u003e The whole point of a prefilled syringe is to be \u003cstrong\u003equick and straightforward\u003c\/strong\u003e:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eThere’s \u003cstrong\u003eno need to draw medicine from a vial\u003c\/strong\u003e (which can be tricky in a high-stress situation).\u003c\/li\u003e\n\u003cli\u003eThe \u003cstrong\u003eplunger is ready to push\u003c\/strong\u003e and deliver the naloxone.\u003c\/li\u003e\n\u003cli\u003eSome products have clear markings and often even come with brief instructions in the kit. In some cases, the syringe might be a specially designed auto-injector (like the now-discontinued Evzio®, which would talk the user through the steps); but typically “prefilled syringe” refers to a more basic design that you operate manually.\u003c\/li\u003e\n\u003cli\u003eThese syringes are \u003cstrong\u003eportable\u003c\/strong\u003e and usually included in opioid overdose rescue kits distributed to opioid users, their friends\/family, first responders, and community organizations. They often have a shelf-life of a year or more and should be stored at room temperature (not extreme heat or freezing) and protected from light.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eExamples of Prefilled Naloxone Syringes:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eOne example is the \u003cstrong\u003e“needle-free” intranasal kit\u003c\/strong\u003e: a 2 mL prefilled naloxone syringe (concentration 1 mg\/mL) that is used with a nasal atomizer. Many public health programs have used this format.\u003c\/li\u003e\n\u003cli\u003eAnother example is \u003cstrong\u003eZIMHI™\u003c\/strong\u003e, a more recently approved product (in the U.S.) which is a \u003cstrong\u003eprefilled single-dose syringe intended for intramuscular injection\u003c\/strong\u003e, containing a 5 mg dose of naloxone in 0.5 mL. It’s designed for layperson use with minimal steps (pull off cap, inject into thigh muscle, push plunger). This provides a higher dose of naloxone for potent synthetic opioid overdoses.\u003c\/li\u003e\n\u003cli\u003eIn some countries, there are prefilled syringes with naloxone that come with standard luer-lock fittings, often used by medical personnel or included in first aid kits (for example, a 1 mL prefilled syringe with 1 mg naloxone HCl for hospital use, or a 2 mL syringe with 2 mg for community use).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eComparison to Other Naloxone Forms:\u003c\/strong\u003e Besides prefilled syringes, naloxone also comes in:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVials or ampoules\u003c\/strong\u003e (small bottles) which require drawing the medication into a syringe manually. This is common in hospitals and EMS but less convenient for untrained people.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNasal sprays\u003c\/strong\u003e (like Narcan® Nasal Spray or generic naloxone nasal spray) which are ready-to-use devices you spray into one nostril—these are easy to use but typically more expensive per dose.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAuto-injectors\u003c\/strong\u003e (like the Evzio® device, which was a talking injector pen with naloxone) – very user-friendly but costly; not as widely available now due to price issues.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe \u003cstrong\u003eprefilled syringe lies somewhat in between\u003c\/strong\u003e the basic vial method and the high-tech auto-injector – it’s relatively inexpensive and straightforward, requiring a little more user action than an autoinjector, but far less than drawing from a vial. Its big advantage is speed and simplicity when every second counts.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"--content-height: undefinedpx;\" class=\"g1ul0 _0ZozC\"\u003e\n\u003cdiv\u003e\n\u003cdiv class=\"mr-3 ml-1\"\u003e\n\u003cdiv class=\"IGO1V\"\u003e\n\u003cp\u003eA naloxone prefilled syringe is a \u003cstrong\u003elife-saving emergency medication device\u003c\/strong\u003e: it’s naloxone in a syringe that’s already filled to the correct dose, allowing rapid injection (often into a muscle) or nasal administration (with an adapter) to counteract opioid overdoses. It's a crucial tool in the effort to reduce fatal overdoses, designed to be user-friendly so that even non-medical individuals can administer naloxone quickly when someone’s life is at risk from opioids.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"International Medication Systems","offers":[{"title":"Default Title","offer_id":16709700164,"sku":"76329-3369-1","price":15.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Naloxone-Prefilled-Syringe-for-Injection-2-mL-by-International-Medication-Systems-3369.jpg?v=1722011251"},{"product_id":"lidocaine-hydrochloride-jelly-2-syringes-100mg-uro-jet-25-box","title":"Lidocaine Jelly 2% Prefilled Syringes 100mg Uro-Jet, 25\/Box (Rx)","description":"Lidocaine Jelly 2% Prefilled Syringes work by numbing the area where it is applied. It is used to treat pain, itching, or burning sensations. It is also used to prevent pain during certain medical procedures. Lidocaine Jelly 2% Prefilled Syringes work by blocking the nerve signals that cause pain.\n\u003cp\u003eInternational Medication Systems Lidocaine Jelly 2%  is a sterile aqueous product that contains a local anesthetic agent and is administered topically. NDC: 76329-3012-05\u003cbr\u003e\u003cbr\u003eLidocaine Hydrochloride Jelly USP, 2% is indicated for prevention and control of pain in procedures involving the male and female  urethra  for  topical  treatment of painful  urethritis,  and  as  an  anesthetic  lubricant  for  endotracheal  intubation (oral and nasal).\u003c\/p\u003e\nBrand: International Medication Systems\u003cbr data-mce-fragment=\"1\"\u003eSize: 5 mL x 25 Units\u003cbr data-mce-fragment=\"1\"\u003eNDC: 76329-3012-05\u003cbr data-mce-fragment=\"1\"\u003eUPC: 763293012050\u003cbr\u003e","brand":"International Medication Systems","offers":[{"title":"Default Title","offer_id":12149159198792,"sku":"76329-3012-05","price":341.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Lidocaine-Jelly-2_-Prefilled-Syringes-100mg-Uro-Jet.jpg?v=1720791761"},{"product_id":"lidocaine-hci-for-injection-2-luer-jet-prefilled-syringe-5-ml-luer-lock","title":"Lidocaine 2% Prefilled Syringe Luer-Jet  100 mg\/5 mL Luer-Lock (Rx)","description":"\u003ch2\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003cstrong\u003ePowerful, Rapid-Acting Local Anesthetic for Emergency, Procedural, and Pain Management Needs\u003c\/strong\u003e\u003c\/span\u003e\u003c\/h2\u003e\n\u003ch4\u003eIndustry-Leading Lidocaine Prefilled Syringe — Fast, Reliable Local and Regional Anesthesia and Cardiac Arrhythmia Solution\u003c\/h4\u003e\n\u003cp\u003eGet maximum convenience and clinical precision with the \u003cstrong\u003eLidocaine 2% (100 mg\/5 mL) Prefilled Syringe Luer-Jet Luer-Lock by International Medication Systems\u003c\/strong\u003e. This hospital-grade, ready-to-administer lidocaine syringe is the gold standard for rapid \u003cstrong\u003elocal anesthesia, nerve block, infiltration, IV line anesthetic flush, and cardiac emergencies such as ventricular arrhythmias\u003c\/strong\u003e. Designed for sterile, single-use delivery in both emergency and planned procedures, this product belongs on every crash cart, ER, dental clinic, and hospital unit.\u003c\/p\u003e\n\u003cp\u003eLidocaine HCI Injection 2% Prefilled Syringes are used as a local anesthetic to provide temporary numbness or loss of sensation in a specific area before surgical, dental, or medical procedures. It works by blocking nerve signals in the body, thus minimizing pain during procedures such as suturing or minor surgeries. Additionally, it can be used to treat certain types of irregular heart rhythms (arrhythmias), making it a valuable tool in emergency medicine. Its quick action and efficiency make it essential for immediate anesthetic needs.\u003c\/p\u003e\n\u003cp\u003eLidocaine HCl Injection 2% by International Medication Systems is a sterile, prefilled syringe solution designed for rapid, effective local anesthesia and acute arrhythmia management. Each 5 mL syringe contains 100 mg of lidocaine hydrochloride, prepared for prompt use in a range of clinical settings. The Luer-Jet Luer-Lock system ensures precise administration and reduces contamination risks, offering healthcare professionals a reliable tool for achieving both peripheral nerve blocks and systemic antiarrhythmic effects.\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eOrder Lidocaine 2% Prefilled Syringe Luer-Jet 100 mg\/5 mL Luer-Lock by International Medication Systems Today!\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eEnsure clinical readiness—stock your crash carts, procedure kits, dental trays, and ER with the pharmacy-grade solution trusted by emergency departments and operating rooms everywhere.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNDC:\u003c\/strong\u003e 76329-3390-01 | \u003cstrong\u003eUPC:\u003c\/strong\u003e 376329339016 \u003cstrong\u003eFor use by licensed medical professionals only. \u003c\/strong\u003e\u003c\/p\u003e","brand":"International Medication Systems","offers":[{"title":"Default Title","offer_id":51680090849648,"sku":"76329-3390-01ea","price":24.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Lidocaine-HCI-for-Injection-2_-Luer-Jet-Prefilled-Syringe-5-mL-by-International-Medication-Systems-3390.jpg?v=1731598680"},{"product_id":"international-medication-systems-epinephrine-prefilled-syringe-1mg-per-10ml-10-pack","title":"Epinephrine Prefilled Syringe 0.1 mg\/mL (1 mg per 10 mL) Each (Rx)","description":"\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003eAn \u003cstrong\u003eEpinephrine Prefilled Syringe\u003c\/strong\u003e is a medical device containing a specific dose of \u003cstrong\u003eepinephrine\u003c\/strong\u003e (also known as adrenaline), already loaded into a syringe and ready for immediate injection. It is designed to be used quickly and easily in emergency situations, most commonly to treat \u003cstrong\u003esevere allergic reactions (anaphylaxis)\u003c\/strong\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eCritical Emergency Medication for Cardiac Arrest and Anaphylactic Shock\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eRely on fast, precise, high-quality emergency care with the Epinephrine Prefilled Syringe 0.1 mg\/mL (1 mg per 10 mL) from International Medication Systems (IMS), the gold-standard for immediate intervention in advanced cardiac life support (ACLS) protocols, anaphylaxis, and severe allergic reactions. This hospital-grade, ready-to-use prefilled syringe is trusted by emergency rooms, intensive care units (ICUs), paramedics, and healthcare professionals nationwide to save lives in seconds when every second counts.\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eWhat is Epinephrine?\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003eIt is a medication and hormone.\u003c\/li\u003e\n\u003cli\u003eUsed to treat \u003cstrong\u003eanaphylaxis\u003c\/strong\u003e, severe asthma attacks, cardiac arrest, and other emergency conditions.\u003c\/li\u003e\n\u003cli\u003eWorks by relaxing the muscles in the airways, tightening blood vessels, and increasing heart rate.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003eWhat is a Prefilled Syringe?\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003eThe syringe is preloaded with a fixed, standard dose (e.g., 0.3 mg for adults, 0.15 mg for children).\u003c\/li\u003e\n\u003cli\u003eIt is sterile, single-use, and ready for injection without needing to measure or draw up medication.\u003c\/li\u003e\n\u003cli\u003eDesigned for \u003cstrong\u003erapid administration\u003c\/strong\u003e during emergencies.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003eCommon Brands and Forms:\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eEpipen\u003c\/strong\u003e and \u003cstrong\u003eAuvi-Q\u003c\/strong\u003e are common \u003cstrong\u003eauto-injectors\u003c\/strong\u003e (slightly different in design from simple prefilled syringes).\u003c\/li\u003e\n\u003cli\u003ePrefilled syringes may be used in hospitals, ambulances, and clinical settings, sometimes instead of auto-injectors.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eHospital-Grade Emergency Adrenaline\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eDelivers \u003cstrong\u003e1 mg epinephrine in 10 mL\u003c\/strong\u003e solution, perfectly dosed for \u003cstrong\u003eintravenous (IV) use in cardiac arrest\u003c\/strong\u003e and \u003cstrong\u003ecode blue situations\u003c\/strong\u003e.\u003c\/li\u003e\n\u003cli\u003ePre-filled, tamper-evident Luer-Lock syringe ensures immediate access and accurate dosing in high-stress emergencies.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eEssential for Cardiac Arrest \u0026amp; Shock\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eFirst-line medication in \u003cstrong\u003eACLS cardiac arrest protocols\u003c\/strong\u003e for asystole, pulseless electrical activity (PEA), and ventricular fibrillation.\u003c\/li\u003e\n\u003cli\u003eCritical for treating \u003cstrong\u003eanaphylactic shock\u003c\/strong\u003e, severe asthma attacks, and life-threatening allergic reactions when IV administration is required.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eTime-Saving, No Preparation Needed\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eReady-to-use, sterile packaging\u003c\/strong\u003e prevents medication errors and saves crucial time during code situations and resuscitation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eTrusted by Medical Professionals\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eManufactured in the USA by \u003cstrong\u003eInternational Medication Systems\u003c\/strong\u003e—a world-class leader in critical care injectables for hospital, EMS, and field medicine use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\u003cstrong\u003eTop Uses \u0026amp; Indications\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eAdvanced Cardiac Life Support (ACLS)\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eCardiac arrest (asystole, PEA, pulseless VT\/VF)\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eAnaphylactic shock (when IV dosing indicated)\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eSevere acute allergic reactions\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eAcute asthma exacerbations\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eSevere hypotension in shock states\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eCode blue drug box and emergency crash cart essentials\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\u003cstrong\u003eWhy Choose IMS Epinephrine Prefilled Syringe?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnmatched Speed:\u003c\/strong\u003e No need for mixing or drawing—simply uncap, connect, and inject for instantaneous response in code situations.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExact Dosing:\u003c\/strong\u003e 0.1 mg\/mL concentration meets current \u003cstrong\u003eACLS guidelines\u003c\/strong\u003e for adult IV bolus administration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSafe \u0026amp; Secure:\u003c\/strong\u003e Sterile, latex-free, and tamper-evident to protect both patient and provider.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUniversal Compatibility:\u003c\/strong\u003e Luer-Lock tip fits all standard IV lines, making it essential for \u003cstrong\u003ehospital crash carts\u003c\/strong\u003e, \u003cstrong\u003eambulance kits\u003c\/strong\u003e, and \u003cstrong\u003efield resuscitation\u003c\/strong\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLong Shelf Life:\u003c\/strong\u003e Stock up for regulatory compliance and continuous readiness.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\u003cstrong\u003eTop Health Search Terms for Epinephrine Prefilled Syringe\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eEpinephrine prefilled syringe 0.1 mg\/mL\u003c\/li\u003e\n\u003cli\u003e1 mg epinephrine for cardiac arrest\u003c\/li\u003e\n\u003cli\u003eACLS emergency epinephrine injection\u003c\/li\u003e\n\u003cli\u003eEpinephrine syringe for code blue\u003c\/li\u003e\n\u003cli\u003eAdrenaline prefilled syringe hospital use\u003c\/li\u003e\n\u003cli\u003eCritical care and resuscitation drugs\u003c\/li\u003e\n\u003cli\u003eEpinephrine IV dose cardiac arrest\u003c\/li\u003e\n\u003cli\u003eCrash cart emergency epinephrine\u003c\/li\u003e\n\u003cli\u003eHospital resuscitation medication\u003c\/li\u003e\n\u003cli\u003eIMS pre-filled epinephrine syringe\u003c\/li\u003e\n\u003cli\u003eBest syringe for anaphylactic shock IV\u003c\/li\u003e\n\u003cli\u003eEpinephrine code cart medication\u003c\/li\u003e\n\u003cli\u003eAdvanced cardiac life support drugs\u003c\/li\u003e\n\u003cli\u003eEpinephrine injection for refill kits\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\u003cstrong\u003eQuick Administration Directions\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoute:\u003c\/strong\u003e For IV use only; administer under direct supervision according to emergency medical protocol (ACLS\/ALS).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSteps:\u003c\/strong\u003e\n\u003col\u003e\n\u003cli\u003eInspect syringe and solution for clarity.\u003c\/li\u003e\n\u003cli\u003eAttach to IV access line or catheter (Luer-lock compatible).\u003c\/li\u003e\n\u003cli\u003eInject as per recommended ACLS dosing: usually 1 mg (10 mL) every 3-5 minutes during resuscitation, or as advised by physician.\u003c\/li\u003e\n\u003cli\u003eMonitor patient continuously.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRead package insert\u003c\/strong\u003e and follow your emergency protocol for specific dosing instructions based on patient age and condition.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\u003cstrong\u003ePossible Side Effects\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eLike all emergency medications, \u003cstrong\u003eepinephrine injection\u003c\/strong\u003e may cause side effects, especially with IV administration:\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eCommon:\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eRapid heartbeat (tachycardia)\u003c\/li\u003e\n\u003cli\u003eIncreased blood pressure (hypertension)\u003c\/li\u003e\n\u003cli\u003eNervousness or anxiety\u003c\/li\u003e\n\u003cli\u003ePalpitations\u003c\/li\u003e\n\u003cli\u003eHeadache\u003c\/li\u003e\n\u003cli\u003eNausea or vomiting\u003c\/li\u003e\n\u003cli\u003eTremor\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eSerious (Seek Medical Help):\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eChest pain, arrhythmias, or heart attack\u003c\/li\u003e\n\u003cli\u003eDifficulty breathing\u003c\/li\u003e\n\u003cli\u003eSevere allergic reaction (rash, swelling, trouble breathing)\u003c\/li\u003e\n\u003cli\u003eHypertensive crisis\u003c\/li\u003e\n\u003cli\u003eStroke\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cblockquote\u003e\n\u003cp\u003e\u003cstrong\u003ePatients must be closely monitored after administration. Report serious adverse reactions immediately to your supervising physician or emergency response team.\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003ch2\u003e\u003cstrong\u003ePrecautions\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eProfessional Use Only:\u003c\/strong\u003e For administration by trained medical personnel under strict monitoring.\u003c\/li\u003e\n\u003cli\u003eUse with caution in patients with cardiovascular disease, hypertension, or hyperthyroidism.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNot for self-administration\u003c\/strong\u003e or home use; hospital\/EMS use only.\u003c\/li\u003e\n\u003cli\u003eStore at room temperature; do not freeze; check for expiration prior to use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003cstrong\u003eEquip your code cart, ambulance, and crash team with the Epinephrine Prefilled Syringe 0.1 mg\/mL (1 mg per 10 mL) by International Medication Systems—the #1 life-saving hospital emergency medication trusted by clinicians and first responders for rapid, precise, and reliable resuscitation when seconds matter most.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"International Medication Systems","offers":[{"title":"Default Title","offer_id":39779377152072,"sku":"76329-3318-01ea","price":28.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Epinephrine-Prefilled-Syringe-0.1-mg_mL-by-International-Medication-Systems_3318.jpg?v=1731541945"},{"product_id":"calcium-chloride-10-injection-prefilled-syringes-1-gram-10ml-100mg-ml-luer-jet-10-box","title":"Calcium Chloride Prefilled Syringe 10%, 1 gram\/10mL (100mg\/mL) (Rx)","description":"\u003cp\u003eCalcium Chloride 10% Injection Prefilled Syringes 1 gram\/10mL International Medication Systems is a high-quality product that works by providing calcium to the body. This product is used to help the body maintain electrolyte levels and prevent or treat low calcium levels. It is also used to help treat or prevent high blood potassium levels.\u003c\/p\u003e\n\u003cp\u003eCalcium chloride 10% injection prefilled syringes 1 gram\/10mL Luer Jet Syringe (International Medication Systems) is a drug that is used to replenish calcium levels in the blood and to treat and prevent cardiac arrest. The drug works by binding to calcium receptors in cardiac and smooth muscle cells, which causes the cells to relax and allows the heart to beat more regularly. The drug also helps to maintain blood pressure by preventing calcium-dependent spasms in the smooth muscle cells in the walls of blood vessels.\u003c\/p\u003e","brand":"International Medication Systems","offers":[{"title":"Default Title","offer_id":39959840915528,"sku":"76329-3304-01ea","price":19.85,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Calcium-Chloride-10_-Injection-Prefilled-Syringes-by-International-Medication-Systems.jpg?v=1749644551"},{"product_id":"dextrose-for-injection-50-prefilled-syringes-luer-jet-luer-lock-50-ml-x-10-box-rx","title":"Dextrose 50% Injection Prefilled Syringes Luer-Jet Luer-Lock 50 mL (Rx)","description":"\u003ch2\u003eImmediate Treatment for Hypoglycemia and Emergency Blood Sugar Restoration\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDextrose 50% Prefilled Syringe\u003c\/strong\u003e by International Medication Systems is the gold-standard, ready-to-use hypertonic glucose solution trusted by \u003cstrong\u003ehospitals, EMS, emergency rooms, and critical care teams\u003c\/strong\u003e. Each 50 mL Luer-Jet Luer-Lock syringe delivers an exact 25 grams of D50W for rapid IV administration—crucial for life-threatening hypoglycemia, insulin shock, or as an emergency carbohydrate source in altered mental status. Pharmaceutically precise, sterile, and preservative-free, this D50 syringe is essential for any crash cart, code blue kit, or ambulance.\u003c\/p\u003e\n\u003ch2\u003eUses\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDextrose 50% Prefilled Syringes are indicated for:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmediate treatment of severe hypoglycemia\u003c\/strong\u003e (low blood sugar) in adults and older children\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAltered mental status of unknown diabetic cause\u003c\/strong\u003e—to rule out\/treat hypoglycemia in unconscious, seizing, or non-responsive patients\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eInsulin shock or diabetic emergencies\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEmergency carb source\u003c\/strong\u003e for perioperative, trauma, or ICU patients unable to take oral\/enteral glucose\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdjunctive therapy in some hyperkalemia protocols\u003c\/strong\u003e (administered with insulin to stabilize serum potassium)\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003ePart of code blue, EMS, and advanced life support (ALS\/ACLS) kits\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eOrder Dextrose 50% Prefilled Syringes (D50W Syringe) – Fastest Solution for Emergency Hypoglycemia Rescue\u003c\/h2\u003e\n\u003cp\u003eEquip your crash carts, ambulances, and emergency rooms with the gold-standard IV glucose solution trusted by professionals for effective hypoglycemia reversal—\u003cstrong\u003eD50W Prefilled Syringe by International Medication Systems\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNDC:\u003c\/strong\u003e 76329-3302-01 | \u003cstrong\u003eUPC:\u003c\/strong\u003e 376329330211 \u003cstrong\u003ePrescription required. Professional and institutional use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"International Medication Systems","offers":[{"title":"Default Title","offer_id":40007822245960,"sku":"76329-3302-01ea","price":34.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Dextrose-for-Injection-50_-Prefilled-Syringes-Luer-Jet-Luer-Lock-50-mL.jpg?v=1697718487"},{"product_id":"sodium-bicarbonate-8-4-luer-jet-prefilled-syringes-50-ml-x-10-pack","title":"Sodium Bicarbonate 8.4% Medication Luer-Jet Syringe 50 mL","description":"\u003ch2\u003eGold-Standard Buffer for Emergency, Critical Care, and Cardiac Code Response\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSodium Bicarbonate 8.4% Prefilled Syringe\u003c\/strong\u003e by International Medication Systems is the trusted, hospital-grade solution for rapid correction of severe metabolic acidosis, cardiac arrest, drug toxicity, renal failure, and critical electrolyte imbalances. Each 50 mL Luer-Jet Luer-Lock syringe delivers precise, sterile dosing for immediate IV administration—essential for every crash cart, emergency department, ICU, and EMS protocol.\u003c\/p\u003e\n\u003cp\u003eInternational Medication Systems 3352 Sodium Bicarbonate 8.4% Luer-Jet Prefilled Syringes 50 mL is a highly effective and widely used medication for the treatment of various medical conditions and emergencies. Sodium Bicarbonate 8.4% Syringes are mainly used for restoring and maintaining the normal pH balance of the blood and body fluids in cases of acidosis, which is caused by conditions such as diabetic ketoacidosis and lactic acidosis. The unique Luer-Jet design of these prefilled syringes allows for easy and accurate administration of the medication, making it a favorite among healthcare professionals. The benefits of using Sodium Bicarbonate 8.4% Syringes are numerous, including rapid and precise correction of acidosis, prevention of further tissue damage, and improved patient outcomes. These prefilled syringes also offer convenience and portability, making them ideal for use in emergency situations and critical care units. With its proven effectiveness and ease of use, International Medication Systems 3352 Sodium Bicarbonate 8.4% Luer-Jet Prefilled Syringes 50 mL has become a trusted choice for healthcare providers worldwide.\u003c\/p\u003e\n\u003ch2\u003eOrder Sodium Bicarbonate 8.4% Medication Luer-Jet Prefilled Syringes 50 mL — The Emergency Buffer Solution for Crash Carts, ICU, and EMS\u003c\/h2\u003e\n\u003cp\u003eBe prepared for any code, acidosis, or toxicologic crisis with the gold-standard, hospital-trusted sodium bicarbonate prefilled syringe. Fast, accurate, and reliable—keep every cart, tray, or advanced life support bag equipped and ready.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNDC:\u003c\/strong\u003e 76329-3352-01 | \u003cstrong\u003eUPC:\u003c\/strong\u003e 376329335216 \u003cstrong\u003ePrescription required. Professional\/Clinical use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"International Medication Systems","offers":[{"title":"Default Title","offer_id":40018654658632,"sku":"76329-3352-01ea","price":36.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Sodium-Bicarbonate-8.4_-Luer-Jet-Prefilled-Syringes-50-mL-International-Medication-Systems.jpg?v=1698767432"},{"product_id":"phytonadione-injectable-emulsion-prefiiled-syringes-neonatal-concentration-1-mg-per-0-5-ml-10-pack-rx","title":"Phytonadione (Vitamin K) Injectable Prefiiled Syringes Neonatal 1 mg Per 0.5 mL 10\/Pack (RX)","description":"\u003cp\u003ePhytonadione Injectable Emulsion Prefilled Syringes Neonatal Concentration 1 mg Per 0.5 mL by International Medication Systems refers to a medication that contains the active ingredient phytonadione, also known as vitamin K1. This medication is specifically designed for use in newborns and is provided in pre-filled syringes with a concentration of 1 mg per 0.5 mL. These syringes are produced by International Medication Systems, a pharmaceutical company. Phytonadione is used to prevent and treat bleeding disorders in newborns, particularly those caused by a vitamin K deficiency.\u003c\/p\u003e\n\u003cp\u003ePhytonadione is a synthetic form of vitamin K, which is important for blood clotting. In neonatal patients, vitamin K deficiency can lead to bleeding disorders, so supplemental vitamin K is often given to prevent this.\u003cbr\u003e\u003cbr\u003ePhytonadione Injectable Emulsion Prefilled Syringes contain a concentration of 1 mg of phytonadione per 0.5 mL of solution. When administered, this injectable emulsion works by increasing the levels of vitamin K in the blood, which in turn helps to produce important clotting factors.\u003cbr\u003e\u003cbr\u003eThe emulsion is prefilled in syringes for convenience and ease of administration in the neonatal population. This formulation allows for accurate dosing and reduces the risk of dosing error.\u003cbr\u003e\u003cbr\u003eOverall, the Phytonadione Injectable Emulsion Prefilled Syringes help to maintain proper blood clotting in neonatal patients and prevent potential bleeding disorders.\u003c\/p\u003e","brand":"International Medication Systems","offers":[{"title":"Default Title","offer_id":40109065306184,"sku":"76329-1240-01","price":725.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Phytonadione-Injectable-Emulsion-Prefiiled-Syringes-Neonatal-Concentration-1-mg.jpg?v=1708616399"},{"product_id":"atropine-sulfate-injection-0-1-mg-ml-luer-jet-prefilled-syringe-10ml-each-rx","title":"Atropine Injection Prefilled Syringe 0.1 mg Luer-Jet 10 mL (Rx)","description":"\u003ch1\u003eAtropine Sulfate (Injection)\u003c\/h1\u003e\n\u003cp\u003eAtropine sulfate is a \u003cstrong\u003epotent anticholinergic (antimuscarinic) drug\u003c\/strong\u003e used in emergency medicine. It blocks acetylcholine at muscarinic receptors throughout the body, thus inhibiting parasympathetic (vagal) activity. In practical terms, atropine \u003cem\u003eincreases heart rate and dries secretions\u003c\/em\u003e. It is formulated for intravenous (or IM) use – often as a 0.1 mg\/mL injection (typically 1 mg in a 10 mL prefilled syringe). According to official prescribing information, “Atropine is a muscarinic antagonist indicated for temporary blockade of severe or life threatening muscarinic effects”. In short, atropine counters dangerous vagal responses, whether in the heart (bradycardia) or elsewhere (excess secretions, bronchospasm, etc.).\u003c\/p\u003e\n\u003ch2\u003eMechanism of Action\u003c\/h2\u003e\n\u003cp\u003eAtropine is a \u003cstrong\u003ecompetitive antagonist at muscarinic acetylcholine receptors\u003c\/strong\u003e. By blocking muscarinic receptors (especially M2 receptors in the heart and M3 in glands), atropine prevents acetylcholine’s effects. This leads to removal of parasympathetic tone: the heart rate rises, secretions (saliva, bronchial mucus) decrease, pupils dilate (mydriasis), bronchial smooth muscle relaxes, and gastrointestinal motility slows. For example, \u003cem\u003estatpearls\u003c\/em\u003e explains that atropine “functions as a competitive, reversible antagonist of muscarinic receptors,” causing \u003cstrong\u003eparasympathetic inhibition\u003c\/strong\u003e so that sympathetic effects (like tachycardia) predominate. This direct “vagolytic” action is why atropine can rapidly reverse acute bradycardia or asystole by blocking the vagus nerve’s slowing influence on the heart.\u003c\/p\u003e\n\u003ch2\u003eIndications and Uses\u003c\/h2\u003e\n\u003cp\u003eAtropine is used in critical care and toxicology settings. Its main FDA-approved roles are to treat \u003cstrong\u003elife-threatening muscarinic overstimulation\u003c\/strong\u003e. Clinically this includes:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSymptomatic bradycardia\/heart block:\u003c\/strong\u003e Atropine is \u003cstrong\u003efirst-line\u003c\/strong\u003e for unstable bradycardia or AV block due to high vagal tone. For example, in advanced cardiac life support (ACLS), IV atropine (0.5–1 mg) is given for symptomatic sinus bradycardia or bradyasystolic arrest. The label notes a \u003cem\u003e1 mg IV\u003c\/em\u003e dose for bradyasystolic cardiac arrest, repeatable every 3–5 minutes if needed. (ACLS guidelines often start at 0.5 mg, but official labeling and many protocols allow 1 mg.)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrganophosphate\/muscarine poisoning:\u003c\/strong\u003e Atropine is the key antidote for cholinergic pesticide or nerve agent poisoning, and muscarinic mushroom toxicity. Large repeated doses (typically 2–3 mg IV or IM, often much higher in severe cases) are given until pulmonary and secretory symptoms abate. In practice, doses may be titrated to effect (occasionally up to tens of milligrams).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntisialagogue \/ Preanesthetic use:\u003c\/strong\u003e Atropine can be used to reduce excessive salivation and secretions or prevent vagal reflexes during surgery\/intubation. A small dose (about 0.4–0.6 mg IV) is given before anesthesia to dry the airway and stabilize heart rate. (It is often used in pediatric intubations to prevent post-induction bradycardia, since children are more vagal.)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiac arrest (asystole\/PEA):\u003c\/strong\u003e In asystolic or PEA cardiac arrest with a suspected bradycardic\/vagal component, atropine (1 mg IV push) may be tried, per ACLS protocols.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eStatpearls confirms these uses, noting atropine’s FDA indications include anti-vagal (bradycardia) effects, antidote for organophosphates, and reduction of vagal tone\/secretions. Off-label, atropine also clears secretions in intubated patients or pretreatment for bradycardia (e.g. during eye surgery). It is \u003cem\u003enot\u003c\/em\u003e effective in β-blocker overdose or non-vagal causes of bradycardia (glucagon is preferred there), but otherwise can be lifesaving in cholinergic crises and severe bradyarrhythmias.\u003c\/p\u003e\n\u003ch2\u003eDosing and Administration\u003c\/h2\u003e\n\u003ch3\u003eAdult Dosing (IV\/IM)\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSymptomatic bradycardia or heart block:\u003c\/strong\u003e Give \u003cstrong\u003e0.5–1 mg IV\u003c\/strong\u003e. Repeat every 3–5 minutes as needed, up to about \u003cstrong\u003e3 mg total\u003c\/strong\u003e. This is most effective for sinus bradycardia and AV nodal block. (Some guidelines use 0.5 mg as first dose, but the product label uses 1 mg for arrest.)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrganophosphate\/muscarinic poisoning:\u003c\/strong\u003e Give \u003cstrong\u003e2–3 mg IV (or IM)\u003c\/strong\u003e, repeat every 20–30 minutes. Titrate to effect (clearance of secretions, improved breathing); doses may exceed 10–20 mg total if needed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntisialagogue (vagal prophylaxis):\u003c\/strong\u003e Give \u003cstrong\u003e0.5–1 mg IV or IM\u003c\/strong\u003e about 30–60 minutes before surgery or intubation. This dose drys secretions and blunts reflex bradycardia.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiac arrest (asystole\/PEA with bradycardia):\u003c\/strong\u003e Give \u003cstrong\u003e1 mg IV push\u003c\/strong\u003e; may repeat per ACLS guidelines if there is a continued vagal component.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePediatric dosing:\u003c\/strong\u003e Typically \u003cstrong\u003e0.01–0.03 mg\/kg IV\u003c\/strong\u003e (minimum 0.1 mg), repeat as needed. (In children, bradycardia is often due to hypoxia, so atropine is used only after airway\/ventilation issues are addressed.)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eAdministration notes:\u003c\/em\u003e Inspect the solution before use; it should be clear. Use aseptic technique. Onset is rapid (IV), peak effect in minutes. Do \u003cstrong\u003enot\u003c\/strong\u003e mix atropine with other drugs in the same syringe or IV line unless compatibility is confirmed. The injection may be given IV push over several seconds, or IM if IV access is not available (onset is slower IM).\u003c\/p\u003e\n\u003ch3\u003eKey Dosage References\u003c\/h3\u003e\n\u003cp\u003eThe official prescribing information and clinical sources align: e.g., one summary states \u003cstrong\u003e“Bradycardia: 1 mg every 3–5 minutes (3 mg max)”\u003c\/strong\u003e, anti-sialagogue \u003cem\u003e0.5–1 mg\u003c\/em\u003e q1–2 h, and \u003cem\u003e“Organophosphate poisoning: 2–3 mg every 20–30 minutes (may require doses up to 20 mg)”\u003c\/em\u003e. These guidelines reflect ACLS and toxicology protocols (repeating atropine doses until desired effect).\u003c\/p\u003e\n\u003ch2\u003eSide Effects and Precautions\u003c\/h2\u003e\n\u003cp\u003eAtropine’s side effects are exactly its expected anticholinergic effects. The most common adverse effects are \u003cstrong\u003edry mouth, blurred vision (due to dilated pupils), photophobia, tachycardia, and flushed, warm skin\u003c\/strong\u003e. Constipation, urinary retention, and decreased sweating (anhidrosis) can also occur, especially in elderly patients. (In overdose or poisoning, these effects intensify – pupils become fully dilated, skin very hot and dry, agitation or delirium may ensue.)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImportant precautions:\u003c\/strong\u003e Because atropine increases heart rate and cardiac workload, use caution in patients with coronary artery disease, angina, or heart failure (excessive tachycardia can worsen ischemia). Acute angle-closure glaucoma is a contraindication: pupil dilation can precipitate a dangerous rise in intraocular pressure. Likewise, atropine should be used cautiously if urinary retention or prostatic hypertrophy is present (it can worsen outflow obstruction). Gastrointestinal or urinary obstruction (e.g. paralytic ileus, pyloric stenosis) are also cautions due to reduced motility. \u003cstrong\u003ePregnancy\/lactation:\u003c\/strong\u003e Atropine crosses the placenta and may cause fetal tachycardia, but no birth defects have been observed. It can be given if clearly needed during pregnancy. ACOG advises that \u003cstrong\u003evigorous treatment of maternal bradycardia (e.g. during obstetric procedures) should not withhold atropine\u003c\/strong\u003e. Atropine appears in breast milk in small amounts; mothers should be monitored for reduced infant feeding or drowsiness if used chronically.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMonitoring:\u003c\/strong\u003e Patients on IV atropine (especially older or cardiac patients) should have ECG monitoring due to risk of arrhythmias. Monitor heart rate, blood pressure, and signs of ischemia. In organophosphate poisoning, monitor secretions and mental status to assess if atropine dosing is adequate. Check urinary output, as atropine’s antidiuresis can lead to fluid retention or dilute hyponatremia during infusion.\u003c\/p\u003e\n\u003ch2\u003eStorage and Handling\u003c\/h2\u003e\n\u003cp\u003eAtropine sulfate injection is supplied as a clear, colorless solution (e.g. 0.1 mg\/mL in a glass syringe). Store at controlled room temperature – generally \u003cstrong\u003e20–25°C (68–77°F)\u003c\/strong\u003e (short excursions 15–30°C are allowed). Protect from light, and do not freeze. Do \u003cem\u003enot\u003c\/em\u003e use past the expiration date. Each syringe or vial is single-use: discard any opened, unused portion. Before administration, inspect visually to confirm clarity and no particulate matter.\u003c\/p\u003e\n\u003cp\u003eAtropine sulfate is a fast-acting muscarinic blocker used in emergencies to counteract life-threatening vagal effects. By blocking parasympathetic tone, it \u003cstrong\u003eraises pulse and dries secretions\u003c\/strong\u003e. Typical uses are for \u003cstrong\u003esymptomatic bradycardia (ACLS), asystolic arrest, organophosphate\/muscarinic poisoning, and pre-anesthetic anti-vagal premedication\u003c\/strong\u003e. Adult IV dosing is usually 0.5–1 mg (repeat as needed), and much larger repeated doses are used in poisonings. Side effects (dry mouth, tachycardia, blurred vision) reflect its anticholinergic action so use caution in glaucoma, urinary retention, and cardiac disease. Proper storage (room temperature) and dilution (already premixed) ensure safe administratio. In sum, atropine sulfate injection is an essential emergency drug for reversible cholinergic crises and severe bradycardia, provided in ready-to-use sterile syringes.\u003c\/p\u003e","brand":"International Medication Systems","offers":[{"title":"Default Title","offer_id":40344751013960,"sku":"76329-3340-01ea","price":32.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Atropine-Sulfate-Injection-0.1-mg-by-International-Medication-Systems-3340.jpg?v=1722510304"},{"product_id":"rextovy-naloxone-nasal-spray-4-mg-2-pack-rx","title":"Rextovy Naloxone Nasal Spray 4 mg (2-Pack) (RX)","description":"\u003cp\u003eRextovy Naloxone Nasal Spray 4 mg is a medication produced by International Medication Systems. It is a prescription nasal spray used to treat opioid overdose in adults, by reversing the effects of opioid drugs. Naloxone is the active ingredient in this medication, and it works by binding to opioid receptors in the brain and blocking the effects of opioids. This can help prevent respiratory failure and death in the case of an opioid overdose. It is important to note that Rextovy Naloxone Nasal Spray should not be used as a substitute for emergency medical care, and individuals who have received the medication should still seek immediate medical attention.\u003c\/p\u003e\n\u003cp\u003eRextovy Naloxone Nasal Spray is an emergency treatment designed to counter the life-threatening effects of opioid overdose. The 4 mg nasal spray is supplied in a convenient 2-pack, offering a ready-to-use, needle-free solution that delivers a potent dose of naloxone—a medication that rapidly reverses the effects of opioids. This product is essential for first responders, caregivers, or anyone who may encounter an opioid-induced respiratory emergency.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey Features:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePotent Rescue Solution:\u003c\/strong\u003e Each nasal spray delivers 4 mg of naloxone hydrochloride, providing an effective antidote in critical overdose situations.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUser-Friendly Design:\u003c\/strong\u003e Compact, easy-to-use device that requires no assembly, with simple instructions that make it accessible even for those without medical training.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmediate Action:\u003c\/strong\u003e Rapidly restores normal breathing and consciousness in individuals experiencing opioid overdoses, including those involving potent opioids like fentanyl.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTwo-Pack \u003c\/strong\u003eConvenience: Comes in a 2-pack for added security and preparedness, ensuring you have a backup readily available if needed.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOptional Paired Applicators\u003c\/strong\u003e: Separate packaging allows you to use one while keeping the other sterile and ready for future emergencies.\u003cstrong\u003e\u003c\/strong\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eUsage Instructions:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Preparation: Tear open the packaging to retrieve the nasal spray.\u003cbr\u003e2. Administration: Insert the nozzle into one nostril, pressing firmly on the applicator to release the dose.\u003cbr\u003e3. Wait and Observe: After administration, call emergency services and wait. If there is no response after 2-3 minutes, administer the second dose using the other nasal spray from the pack.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSafety Information:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Keep the product in its original packaging until needed. Store at room temperature, away from light and moisture.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWarnings:\u003c\/strong\u003e Be aware that naloxone may precipitate withdrawal symptoms in opioid-dependent individuals. Do not use the product if the packaging is damaged.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExpiration: \u003c\/strong\u003eEnsure to check the expiration date regularly and replace as needed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eWho Should Carry Rextovy Naloxone Nasal Spray:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFirst responders and healthcare providers.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eFamily members or caregivers of individuals with opioid prescriptions or at risk of overdose.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eCommunity organizations and drug treatment centers.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eTeachers, coaches, or leaders in environments where an opioid overdose risk exists.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eManufactured by:\u003c\/strong\u003e Rextovy Pharmaceuticals, known for their commitment to producing high-quality, life-saving medical products.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eRextovy Naloxone Nasal Spray is for emergency use only and is not a substitute for professional medical care. Always seek immediate medical attention following its administration.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTake Action, Save Lives:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEquip yourself with Rextovy Naloxone Nasal Spray and be prepared to act in the event of an opioid overdose. Your preparedness can make the difference between life and death.\u003c\/p\u003e","brand":"International Medication Systems","offers":[{"title":"Default Title","offer_id":40376290050120,"sku":"76329-3669-02","price":69.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Rextovy-Naloxone-Nasal-Spray-4-mg-International-Medication-Systems-76329-3669-02.jpg?v=1724071948"},{"product_id":"procainamide-hcl-injection-100-mg-luer-jet-prefilled-syringe-treat-irregular-heartbeats","title":"Procainamide Injection Prefilled Syringes 100 mg\/mL Luer-Jet 10 mL x 5\/Pack","description":"\u003cp\u003e\u003cstrong\u003eProcainamide Hydrochloride Injection\u003c\/strong\u003e is a fast-acting antiarrhythmic agent provided in a convenient Luer-Jet prefilled syringe, ensuring rapid response and precise dosing in urgent clinical situations. Each pack includes five 10 mL prefilled syringes (total 5000 mg procainamide per pack), perfectly suited for emergency departments, critical care, and hospital settings where reliability and sterility are paramount.\u003c\/p\u003e\n\u003ch3\u003eWhat Is Procainamide HCl Injection Used For?\u003c\/h3\u003e\n\u003cp\u003eProcainamide HCl Injection is indicated for:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTreatment and prevention of life-threatening cardiac arrhythmias\u003c\/strong\u003e, including sustained ventricular tachycardia.\u003c\/li\u003e\n\u003cli\u003eTemporary control of arrhythmias during anesthesia, surgery, or myocardial infarction.\u003c\/li\u003e\n\u003cli\u003eStabilizing acute ventricular arrhythmias when oral therapy is not possible or rapid intervention is required.\u003c\/li\u003e\n\u003cli\u003eAs an alternative when other antiarrhythmic agents are contraindicated or ineffective.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Details \u0026amp; Features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eActive Ingredient:\u003c\/strong\u003e Procainamide Hydrochloride, 100 mg\/mL\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVolume:\u003c\/strong\u003e 10 mL per prefilled syringe (1,000 mg per syringe)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePackaging:\u003c\/strong\u003e 5 syringes per package (total 5,000 mg per pack)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdministration Route:\u003c\/strong\u003e Intravenous (IV) use only\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eManufacturer:\u003c\/strong\u003e International Medication Systems (IMS)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSterile \u0026amp; Pyrogen-Free:\u003c\/strong\u003e Designed for rapid hospital or EMS administration\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLuer-Jet Prefilled Syringe:\u003c\/strong\u003e Reduces medication preparation time, ensures sterility, and delivers precise dosing instantly\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eLatex-free, Single-Use Syringe\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eKey Features\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRapid Onset:\u003c\/strong\u003e For immediate control of dangerous arrhythmias.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConsistent Dosing:\u003c\/strong\u003e Prefilled syringes minimize dosing errors and maximize clinical efficiency.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSterile \u0026amp; Tamper-Evident:\u003c\/strong\u003e Enhances patient safety and infection control standards.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConvenient Multipack:\u003c\/strong\u003e Ideal for high-use clinical environments.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eDirections for Use\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eInspect\u003c\/strong\u003e the syringe and solution for particles or discoloration before use. Do not use if the solution appears cloudy, discolored, or if the packaging is damaged.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAseptic Technique:\u003c\/strong\u003e Always use proper aseptic technique when handling and administering injections.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConnect\u003c\/strong\u003e the Luer-Jet syringe to a compatible IV access device.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdminister IV Slowly:\u003c\/strong\u003e Inject directly into the intravenous line or catheter as directed by a physician.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMonitor:\u003c\/strong\u003e Continuously monitor the patient’s ECG, blood pressure, and clinical status during administration.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch3\u003eDosage\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAdults:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eInitial IV Loading Dose:\u003c\/strong\u003e 20 mg\/minute until arrhythmia is controlled, QRS complex widens by 50%, or a total of 17 mg\/kg is administered.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMaximum Single Dose:\u003c\/strong\u003e Do not exceed 1 gram in a single loading dose.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMaintenance Dose:\u003c\/strong\u003e Continuous IV infusion of 1–4 mg\/min as needed, titrated to clinical response.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eChildren:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eInitial Loading Dose:\u003c\/strong\u003e 3–6 mg\/kg administered IV over 5–10 minutes, under continuous ECG monitoring.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMaintenance:\u003c\/strong\u003e Individualized and physician-directed, based on clinical response.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eImportant:\u003c\/strong\u003e Dosage must be individualized and titrated to therapeutic response. Always verify recommended dosages with current clinical guidelines and facility protocols.\u003c\/p\u003e\n\u003ch3\u003eCDC Guidelines \u0026amp; Best Practices\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrict Aseptic Technique:\u003c\/strong\u003e Adhere to CDC clinical standards for injection safety and infection control.\n\u003cul\u003e\n\u003cli\u003eNever reuse syringes or needles.\u003c\/li\u003e\n\u003cli\u003eUse a new, sterile syringe and needle per patient.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMonitor for Adverse Events:\u003c\/strong\u003e ECG and blood pressure should be continuously monitored throughout administration and recovery.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProper Staff Training:\u003c\/strong\u003e Only qualified healthcare professionals experienced in antiarrhythmic drug therapy should administer procainamide.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdverse Event Reporting:\u003c\/strong\u003e Report any medication errors or adverse events according to institutional and regulatory requirements.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWarnings\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eProarrhythmic Effect:\u003c\/strong\u003e Procainamide can induce or worsen certain arrhythmias—continuous ECG monitoring is required.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eComplete Heart Block:\u003c\/strong\u003e Contraindicated in patients with complete heart block in absence of a functioning artificial pacemaker.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypersensitivity:\u003c\/strong\u003e Contraindicated in patients with known hypersensitivity to procainamide or related drugs (procainamide, procaine, etc.).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug-Induced Lupus Erythematosus:\u003c\/strong\u003e Long-term use may result in a lupus-like syndrome.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBlood Dyscrasias:\u003c\/strong\u003e Risk of agranulocytosis, neutropenia, and thrombocytopenia; perform regular blood count monitoring if prolonged use is anticipated.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypotension:\u003c\/strong\u003e Rapid IV administration can cause severe hypotension; administer slowly and monitor hemodynamics.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRenal or Hepatic Impairment:\u003c\/strong\u003e Adjust dosage accordingly and monitor closely.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003ePossible Side Effects\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eCommon:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNausea, vomiting\u003c\/li\u003e\n\u003cli\u003eAbdominal pain\u003c\/li\u003e\n\u003cli\u003eDizziness or lightheadedness\u003c\/li\u003e\n\u003cli\u003eFlushing\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSerious:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSevere hypotension\u003c\/li\u003e\n\u003cli\u003eHeart block or worsened arrhythmias\u003c\/li\u003e\n\u003cli\u003eLupus-like symptoms (joint pain, fever, rash)\u003c\/li\u003e\n\u003cli\u003eBlood disorders (agranulocytosis, neutropenia)\u003c\/li\u003e\n\u003cli\u003eAllergic reactions: rash, itching, swelling, difficulty breathing (seek immediate medical attention)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMonitor patient closely during and after administration for any unexpected side effects or adverse reactions.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProcainamide HCl Injection 100 mg\/mL Luer-Jet Prefilled Syringe 10 mL x 5\/Pack\u003c\/strong\u003e by International Medication Systems: When every second counts, trust a rapid, reliable, and precise solution for acute cardiac arrhythmia management. For professional hospital and emergency use only.\u003c\/p\u003e\n\u003cp\u003eAlways consult a licensed healthcare provider for guidance. Use as directed.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan class=\"block _00hoS\"\u003eInternational Medication Systems – Precise Care in Every Syringe.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e","brand":"International Medication Systems","offers":[{"title":"Default Title","offer_id":52345089556848,"sku":"76329-3399-05","price":699.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Procainamide-HCl-Injection-Luer-Jet-Prefilled-Syringe-10-mL.jpg?v=1750166867"},{"product_id":"lidocaine-urojet-hcl-topical-jelly-2-prefilled-syringe-urethral-pain-relief","title":"Lidocaine Urojet HCl Topical Jelly 2% Prefilled Syringe 10 mL x 25\/Pack (Rx)","description":"\u003cp\u003e\u003cstrong\u003eLidocaine Urojet HCl Topical Jelly 2% PF\u003c\/strong\u003e is a preservative-free, sterile local anesthetic designed for fast, effective pain relief and anesthesia in urological and surgical procedures. Each 10 mL prefilled syringe is conveniently packaged, latex-free, and ready for immediate single-use application, making it the trusted choice for hospitals, clinics, surgical suites, and urology practices. Available from International Medication Systems, this multipack of 25 ensures continuous, reliable access for your procedural needs.\u003c\/p\u003e\n\u003ch3\u003eWhat It Is Used For\u003c\/h3\u003e\n\u003cp\u003eLidocaine Urojet HCl Topical Jelly 2% PF is indicated for:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eLocal anesthesia of the mucous membranes\u003c\/strong\u003e of the urethra and urinary tract.\u003c\/li\u003e\n\u003cli\u003eReduced pain and discomfort during \u003cstrong\u003ecatheterization\u003c\/strong\u003e, cystoscopy, endoscopy, and other urological procedures.\u003c\/li\u003e\n\u003cli\u003eProviding topical analgesia for short surgical procedures or diagnostic interventions involving the genitourinary tract.\u003c\/li\u003e\n\u003cli\u003eAdditional minor procedures requiring local mucosal anesthesia.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Details \u0026amp; Features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eActive Ingredient:\u003c\/strong\u003e Lidocaine Hydrochloride 2% (20 mg\/mL)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Preservative-Free (PF) to reduce risk of allergic reaction or irritation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePackaging:\u003c\/strong\u003e 10 mL sterile, latex-free, prefilled syringe; 25 syringes per box.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSingle-Use, Ready-to-Use:\u003c\/strong\u003e Reduces preparation time and risks of cross-contamination.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTransparent, colorless, water-soluble jelly:\u003c\/strong\u003e Enables visualization and cleanliness.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNo need for mixing or measuring:\u003c\/strong\u003e Each syringe offers precise dosing.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eKey Features\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFast-acting numbing:\u003c\/strong\u003e Begins anesthetic effect within 3–5 minutes of administration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFlexible use:\u003c\/strong\u003e Suitable for a variety of minor diagnostic and therapeutic urological procedures.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMinimized infection risk:\u003c\/strong\u003e Prefilled, single-use syringes ensure sterility and patient safety.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConvenient and portable:\u003c\/strong\u003e Multipack design is ideal for high-volume practice settings.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLatex- and preservative-free:\u003c\/strong\u003e Safer for sensitive patients and those with allergies.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eDirections for Use\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003eConfirm the integrity of the syringe and ensure the jelly is clear and free of particulates before use.\u003c\/li\u003e\n\u003cli\u003eUse standard aseptic technique and wear gloves.\u003c\/li\u003e\n\u003cli\u003eRemove the protective tip cap from the syringe. Attach a sterile applicator or catheter if needed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFor urethral anesthesia:\u003c\/strong\u003e Slowly instill the jelly directly into the urethra. The usual amount is up to 10 mL for adults, but dosing may vary per procedure.\u003c\/li\u003e\n\u003cli\u003eAllow 3–5 minutes for full anesthetic effect before proceeding.\u003c\/li\u003e\n\u003cli\u003eDiscard any unused portion and dispose of syringe properly after a single use.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch3\u003eDosage\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAdults:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eUrethral Instillation:\u003c\/strong\u003e Up to 10 mL (200 mg lidocaine) as a single dose for adults before procedures.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOther Topical Applications:\u003c\/strong\u003e Dosage may vary by mucosal site and procedure. Do not exceed recommended total daily dosage—\u003cstrong\u003emaximum lidocaine dose is usually 4.5 mg\/kg or 300 mg per procedure for adults.\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003eAlways follow physician instructions and institutional protocols regarding total allowable dose, especially if other forms of lidocaine are being administered.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003ePediatric Use:\u003c\/strong\u003e Dosage must be carefully calculated based on child’s weight and age. Consult pediatric dosing guidelines.\u003c\/p\u003e\n\u003ch3\u003eCDC Guidelines \u0026amp; Clinical Best Practices\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrict aseptic technique:\u003c\/strong\u003e Follow CDC infection prevention standards for all urological and perioperative procedures.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSingle-patient, single-use:\u003c\/strong\u003e Never reuse syringes. Discard immediately after use, even if some jelly remains.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePatient monitoring:\u003c\/strong\u003e Observe patient for signs of systemic toxicity or allergic reactions during and after the procedure.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDocumentation:\u003c\/strong\u003e Record dosage, site of application, time, and any notable patient reactions as part of clinical documentation protocol.\u003c\/li\u003e\n\u003cli\u003eEnsure all healthcare staff are trained and competent in local anesthetic administration per facility and CDC guidelines.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWarnings\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNot for injection:\u003c\/strong\u003e Lidocaine Urojet is for topical\/mucosal use only; do not inject.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllergy Risk:\u003c\/strong\u003e Contraindicated in patients with known hypersensitivity to amide-type local anesthetics.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystemic Toxicity:\u003c\/strong\u003e Excessive doses, rapid absorption, or application to large mucosal areas can cause serious effects including CNS and cardiovascular toxicity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUse in Pediatrics\/Pregnancy:\u003c\/strong\u003e Use with caution; adhere to appropriate dosing and consult specialist guidance.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSevere Hepatic Disease:\u003c\/strong\u003e Lidocaine is metabolized by the liver; reduce dose and monitor closely.\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eDo not use if solution is discolored or if package integrity is compromised.\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003ePossible Side Effects\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eCommon:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTemporary redness, irritation, or mild burning at the application site\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eLess Common\/Serious:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSystemic CNS effects: Drowsiness, confusion, dizziness, seizures (if overdosed or absorbed in excess)\u003c\/li\u003e\n\u003cli\u003eCardiovascular: Hypotension, bradycardia, arrhythmias (rare, usually only with massive overapplication or rapid absorption)\u003c\/li\u003e\n\u003cli\u003eAllergic reactions: Rash, itching, swelling, difficulty breathing (seek immediate medical help if these occur)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eLidocaine Urojet HCl Topical Jelly 2% PF Prefilled Syringe 10 mL x 25\/Pack\u003c\/strong\u003e by International Medication Systems: The trusted solution for fast, effective mucosal anesthesia in urological and genitourinary procedures. Experience safety, reliability, and convenience in every application.\u003c\/p\u003e\n\u003cp\u003eFor professional healthcare use only. Always follow clinical guidelines and consult the product insert for full prescribing information.\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"block _00hoS\"\u003e\u003cstrong\u003eInternational Medication Systems – Excellence in Sterile Delivery, Every Time.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"International Medication Systems","offers":[{"title":"Default Title","offer_id":52345195856240,"sku":"76329-3013-05","price":375.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Lidocaine-Urojet-HCl-Topical-Jelly-2_-Prefilled-Syringe.jpg?v=1750176178"},{"product_id":"lidocaine-urojet-hcl-topical-jelly-2-prefilled-syringe-20-ml-x-25-pack","title":"Lidocaine Urojet HCl Topical Jelly 2% Prefilled Syringe Numbing 20 mL x 25\/Pack","description":"\u003cp\u003e\u003cstrong\u003eLidocaine Urojet HCl Topical Jelly 2%\u003c\/strong\u003e is a sterile, preservative-free local anesthetic topical jelly designed for fast, effective numbness and pain relief for a variety of urological and minor surgical procedures. Each prefilled 20 mL syringe delivers a precise, ready-to-use dose to ensure maximum sterility, efficiency, and patient safety. This pack includes 25 single-use syringes, making it ideal for high-volume hospitals, clinics, ambulatory surgical centers, urology practices, and emergency rooms.\u003c\/p\u003e\n\u003ch3\u003eWhat It Is Used For\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eLocal anesthesia of the urethra and mucous membranes of the urinary tract\u003c\/li\u003e\n\u003cli\u003eReducing pain and discomfort during male and female \u003cstrong\u003eurethral catheterization\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003eProviding local anesthesia prior to cystoscopy, endoscopy, or other \u003cstrong\u003eurological, gynecological, and minor surgical procedures\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003eFacilitating passage of diagnostic or therapeutic instruments while minimizing patient discomfort\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Details \u0026amp; Features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eActive Ingredient:\u003c\/strong\u003e Lidocaine Hydrochloride 2% (20 mg\/mL)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSyringe Volume:\u003c\/strong\u003e 20 mL per prefilled, sterile, single-use syringe\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePackaging:\u003c\/strong\u003e 25 syringes per box (total 500 mL\/per pack)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Preservative-free to reduce allergy risk and irritation\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eColorless, aqueous, water-soluble jelly\u003c\/strong\u003e for clear application\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eLatex-free, DEHP-free packaging\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConvenient and efficient:\u003c\/strong\u003e Ready for immediate use with no need for mixing or measuring\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eReduces cross-contamination and preparation time\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003eTrusted by urologists and healthcare professionals worldwide\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eDirections for Use\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eInspect\u003c\/strong\u003e syringe for packaging integrity and solution clarity. Do not use if the solution is cloudy, colored, or if the packaging is damaged.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAseptic technique:\u003c\/strong\u003e Wash hands and use sterile gloves.\u003c\/li\u003e\n\u003cli\u003eRemove the protective cap from the syringe tip.\u003c\/li\u003e\n\u003cli\u003eAttach a sterile applicator, catheter adapter, or nozzle as necessary for procedure.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInstill the jelly slowly\u003c\/strong\u003e and gently into the urethra or apply directly to mucous membranes, according to procedure need.\u003c\/li\u003e\n\u003cli\u003eWait 3–5 minutes to allow maximum anesthetic effect before proceeding with the medical procedure.\u003c\/li\u003e\n\u003cli\u003eSafely discard the syringe after single use, even if some jelly remains.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch3\u003eDosage\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdults:\u003c\/strong\u003e Typical urethral dosage is up to 20 mL (400 mg lidocaine) per procedure.\u003c\/li\u003e\n\u003cli\u003eFor catheterization, instill the entire contents (20 mL) to coat and anesthetize the mucosa thoroughly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMaximum recommended total dose:\u003c\/strong\u003e Do not exceed 4.5 mg\/kg (maximum 300 mg per single dose for most adult patients). If using multiple preparations containing lidocaine, calculate total systemic dosage.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePediatrics:\u003c\/strong\u003e Dosage must be strictly based on child’s weight and medical guidance; consult pediatric protocols.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCDC Guidelines \u0026amp; Best Practices\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eUse aseptic technique\u003c\/strong\u003e to prevent introduction of pathogens (CDC Standard Precautions).\u003c\/li\u003e\n\u003cli\u003eUse only single-use, sterile syringes per patient. Never reuse, flush, or split between patients.\u003c\/li\u003e\n\u003cli\u003eProperly dispose of all used medical devices in accordance with facility and CDC biomedical waste guidelines.\u003c\/li\u003e\n\u003cli\u003eMonitor the patient for allergic reactions or signs of toxicity during and after administration.\u003c\/li\u003e\n\u003cli\u003eDocument the dosage, site of application, and patient tolerance in the medical record.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWarnings\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNot for injection\u003c\/strong\u003e: For topical\/mucosal use only.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllergy Alert:\u003c\/strong\u003e Contraindicated in patients sensitive to amide-type local anesthetics.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystemic Toxicity:\u003c\/strong\u003e Do not exceed recommended dose. Lidocaine overdose can cause central nervous system and cardiac adverse reactions.\u003c\/li\u003e\n\u003cli\u003eUse with caution in patients with \u003cstrong\u003esevere hepatic disease, cardiac conduction disturbances, or those taking class I antiarrhythmic drugs.\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003eFor use under supervision of trained healthcare professionals only.\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eDo not apply to inflamed or severely traumatized mucosa unless directed by a physician.\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003eNot recommended for use in children below two years unless directed by a specialist.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSide Effects\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eCommon Side Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLocalized redness, irritation, or mild burning at application site\u003c\/li\u003e\n\u003cli\u003eMild tissue swelling or tingling\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSerious or Rare Side Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSystemic CNS toxicity: dizziness, drowsiness, tremors, anxiety, confusion, seizures (usually only after overdose or rapid absorption)\u003c\/li\u003e\n\u003cli\u003eCardiovascular reactions: hypotension, bradycardia, arrhythmia\u003c\/li\u003e\n\u003cli\u003eAllergic reactions: rash, itching, swelling, difficulty breathing (rare but require immediate medical attention)\u003c\/li\u003e\n\u003cli\u003eMethemoglobinemia (very rare): Watch for blue\/gray skin, headache, fatigue, or rapid breathing\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003ePatient should be observed for signs of toxicity, especially with repeated or large applications. Seek immediate medical attention if severe reactions occur.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLidocaine Urojet HCl Topical Jelly 2% Prefilled Syringe 20 mL x 25\/Pack\u003c\/strong\u003e is the preferred choice for clinicians seeking fast, effective, and safe urological anesthesia in a sterile, convenient format.\u003c\/p\u003e\n\u003cp\u003eFor professional use only. Always follow institutional protocols and product labeling.\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"block _00hoS\"\u003e\u003cstrong\u003eInternational Medication Systems – Reliability and Safety in Every Dose.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"International Medication Systems","offers":[{"title":"Default Title","offer_id":52345213944176,"sku":"76329-3015-05","price":475.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Lidocaine-Urojet-HCl-Topical-Jelly-2-Prefilled-Syringe-20-mL.jpg?v=1750177362"},{"product_id":"iron-sucrose-injection-20-mg-ml-single-dose-vial-2-5-ml-x-10-pack-rx","title":"Iron Sucrose Injection 20 mg\/mL SIngle-Dose Vial 2.5 mL x 10\/Pack (RX)","description":"\u003ch1\u003eIron Sucrose Injection\u003c\/h1\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003e Iron sucrose injection (20 mg\/mL, 2.5 mL single-dose vial) is an \u003cstrong\u003eintravenous iron replacement\u003c\/strong\u003e product marketed by International Medication Systems, Limited (IMS). Each 2.5 mL vial contains 50 mg elemental iron as iron(III)-hydroxide sucrose complex (20 mg\/mL). The vial is preservative-free and intended for single use only – any unused portion must be discarded. This IMS formulation is a generic equivalent of branded iron sucrose products (e.g. Venofer®). It is used only by prescription, under medical supervision. Iron sucrose injection is \u003cstrong\u003efor intravenous use only\u003c\/strong\u003e (via slow IV injection or infusion), and \u003cstrong\u003enot given intramuscularly or orally\u003c\/strong\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\n\u003cspan class=\"VODHU pdMy8\"\u003eMechanism of Action\u003c\/span\u003e:\u003c\/h2\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003eIron sucrose is a complex of polynuclear iron(III)-hydroxide in a sucrose shell. After IV administration, the complex dissociates: iron is released and binds transferrin in the blood. Transferrin carries iron to the bone marrow and other target tissues. In erythroid precursor cells, the delivered iron is incorporated into hemoglobin and new red blood cells. Excess iron is stored in liver, spleen and bone marrow until needed. The sucrose moiety is largely excreted unchanged by the kidneys. Because it delivers iron directly to the bloodstream, iron sucrose promptly raises serum iron and ferritin levels, improving anemia where oral iron cannot suffice.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan class=\"VODHU pdMy8\"\u003eIndications:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003eBy label [IMS and FDA], iron sucrose injections are \u003cstrong\u003eindicated for treatment of iron-deficiency anemia (IDA) in patients with chronic kidney disease (CKD)\u003c\/strong\u003e. This includes adult and pediatric CKD patients on hemodialysis, peritoneal dialysis, or those not yet on dialysis. The efficacy in CKD is well established: iron sucrose is given along with erythropoiesis-stimulating agents (ESAs) to help achieve target hemoglobin levels. (In practice, intravenous iron is preferred in CKD because these patients often have ongoing blood losses, inflammation, or poor oral absorption.)\u003c\/p\u003e\n\u003cp\u003eIron sucrose is also used \u003cem\u003eoff-label\u003c\/em\u003e for other severe iron-deficiency states. For example, it is commonly given for iron-deficiency anemia in \u003cstrong\u003epregnancy or postpartum\u003c\/strong\u003e when oral iron fails or is not tolerated, or in cases of heavy uterine bleeding. It is sometimes used for anemia in inflammatory bowel disease, celiac disease, bariatric surgery, or any condition causing malabsorption, and in cancer patients on chemotherapy. Expert guidelines (e.g. American Society of Hematology) advise using intravenous iron when oral therapy is intolerable or too slow – such as moderate-to-severe anemia or when a quick correction is needed. Some clinicians use IV iron to avert blood transfusions. However, outside CKD such use is “off-label” and should follow clinical judgment. (Notably, major pediatric societies and obstetric guidelines emphasize checking for iron deficiency in these contexts and treating it, often recommending IV iron if oral fails, despite official label being CKD-only.)\u003c\/p\u003e\n\u003ch2\u003e\u003cspan class=\"VODHU pdMy8\"\u003eDosage and Administration:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003eIron sucrose is supplied in single-dose vials of 2.5 mL (50 mg), 5 mL (100 mg), and 10 mL (200 mg), all at 20 mg\/mL. Dilution is done only with 0.9% sodium chloride. The final concentration should be 1–2 mg iron\/mL (no less than 1 mg\/mL) if dilution is needed. Do \u003cstrong\u003enot\u003c\/strong\u003e mix with other IV drugs or dextrose – use a dedicated line.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan class=\"VODHU pdMy8\"\u003eAdministration: \u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003e Iron sucrose must be infused or injected \u003cstrong\u003eslowly\u003c\/strong\u003e to minimize reactions. For \u003cem\u003ehemodialysis-dependent CKD (HDD-CKD)\u003c\/em\u003e, a common regimen is 100 mg IV at each dialysis (3 times weekly) until ~1000 mg total is given. Each 100 mg dose can be given as a 2–5 minute IV push or a 15-minute infusion (diluted to ≤100 mL saline); it is often administered early in the dialysis session. For \u003cem\u003enon-dialysis CKD (NDD-CKD)\u003c\/em\u003e, typical dosing is 200 mg IV per dose, given \u003cstrong\u003efive times over 2 weeks\u003c\/strong\u003e (e.g. 200 mg on days 1, 4, 7, 10, 13; total 1000 mg). The 200 mg doses can be given as IV push (2–5 minutes) or 15-minute infusions (diluted in ≤100 mL). In some protocols, a 500 mg infusion over ~4 hours on Day 1 and Day 14 has been used, though this is less common. For \u003cem\u003eperitoneal dialysis (PDD-CKD)\u003c\/em\u003e, the usual course is three doses over ~4 weeks: 300 mg IV (over 1.5 h) on day 1 and day 15, then 400 mg IV (over 2.5 h) on day 29 (total 1000 mg) . Again, dilute each dose in ≤250 mL saline. Iron sucrose therapy may be repeated if anemia recurs after completion of a course.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003eFor pediatric patients (≥2 years old) on dialysis receiving ESAs, iron maintenance dosing studied was \u003cstrong\u003e0.5 mg\/kg IV (max 100 mg)\u003c\/strong\u003e every 2–4 weeks). (This was shown to maintain hemoglobin in many children.) Iron sucrose is \u003cstrong\u003enot established for initial anemia correction in children\u003c\/strong\u003e (except in CKD\/ESA context). It has been given in some pediatric CKD cases for maintenance. It has not been studied in infants under 2 years, and caution is warranted there. In very low-birthweight neonates (premature \u0026lt;1250 g), there are case reports of necrotizing enterocolitis temporally associated with IV iron; causal relation is unclear, but it underscores caution in infant.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan class=\"VODHU pdMy8\"\u003eContraindications: \u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003eIron sucrose injection should not be used in any patient with known hypersensitivity\/allergy to iron sucrose or any component (sucrose, etc.). Also avoid use in patients with iron overload (e.g. hemochromatosis or very high ferritin\/TSAT) because excess iron can cause tissue damage.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan class=\"VODHU pdMy8\"\u003eWarnings\/Precautions:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003eThe most serious risks are \u003cstrong\u003ehypersensitivity reactions\u003c\/strong\u003e and \u003cstrong\u003ehypotension\u003c\/strong\u003e. Acute allergic\/anaphylactic reactions (flushing, wheezing, hypotension, shock, severe rash or swelling) have been reported, though less commonly with iron sucrose than older iron dextrans. Always administer IV iron sucrose in a setting where resuscitation is available. Observe the patient during and for ≥30 minutes after each infusion for signs of allergy. If bronchospasm or anaphylaxis occur, stop the infusion immediately and treat (epinephrine, IV fluids, etc.). Patients with a history of asthma, atopy, or previous reactions to iron are higher risk.\u003c\/p\u003e\n\u003cp\u003eIron sucrose can cause \u003cstrong\u003ehypotension\u003c\/strong\u003e if infused too rapidly or in sensitive patients. To minimize this, infuse slowly and monitor blood pressure. If significant hypotension or syncope occurs, stop infusion, put patient supine, and give IV fluids. (Note: severe maternal hypotension in pregnancy could secondarily compromise fetal perfusion, so extra vigilance is needed obstetrically.)\u003c\/p\u003e\n\u003cp\u003eChronic overuse can lead to \u003cstrong\u003eiron overload (hemosiderosis)\u003c\/strong\u003e. Iron is not easily excreted, so repeated IV dosing can accumulate. Check serum ferritin and transferrin saturation (TSAT) periodically during therapy. Do \u003cem\u003enot\u003c\/em\u003e give additional iron if ferritin is very high (typically \u0026gt;500–1000 ng\/mL) or TSAT exceeds 50%. Maintain target hemoglobin levels and stop iron when stores are adequate.\u003c\/p\u003e\n\u003ch2\u003e\n\u003cspan class=\"VODHU pdMy8\"\u003eSide Effects\u003c\/span\u003e:\u003c\/h2\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003eCommon adverse effects include \u003cstrong\u003egastrointestinal symptoms\u003c\/strong\u003e (nausea, vomiting, diarrhea, constipation) and \u003cstrong\u003eCNS symptoms\u003c\/strong\u003e (headache, dizziness). Other frequent reactions are \u003cstrong\u003ehypotension\u003c\/strong\u003e (often mild or asymptomatic), \u003cstrong\u003emusculoskeletal pain\u003c\/strong\u003e (cramps, arthralgia, back pain), \u003cstrong\u003eflushing\/itching or skin rash\u003c\/strong\u003e (pruritus), and \u003cstrong\u003einjection site reactions\u003c\/strong\u003e. Chest pain or hypertension may also occur These are generally transient. Serious side effects are rare but include severe allergy or shock, and very rarely serious cardiac or renal events if iron is given too rapidly. Patients should report any dyspnea, chest discomfort, or extensive rash during infusion.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003ePregnancy:\u003c\/h2\u003e\n\u003cp\u003eIron sucrose is rated \u003cstrong\u003eCategory B\u003c\/strong\u003e (no evidence of harm in animal studies). Studies of IV iron sucrose \u003cem\u003eafter\u003c\/em\u003e the first trimester have not shown increased risk of birth defects. Data in the first trimester are limited, so it is usually reserved for second\/third trimester unless anemia is severe and cannot be delayed. Importantly, \u003cstrong\u003euntreated iron-deficiency anemia in pregnancy carries risks\u003c\/strong\u003e (premature delivery, low birth weight, maternal morbidity), so treating significant IDA is recommended (often after 12 weeks if oral fails). IMS labeling notes that pregnant women have not shown adverse outcomes when treated in later pregnancy. However, if a severe infusion reaction occurs (hypotension, anaphylaxis), maternal hypotension could harm the fetus, so maternal vitals and fetal heart rate should be monitored as needed.\u003c\/p\u003e\n\u003ch2\u003eLactation:\u003c\/h2\u003e\n\u003cp\u003eIron sucrose does pass into breast milk, but published data show \u003cstrong\u003eno reported adverse effects in breastfed infants\u003c\/strong\u003e (e.g. in women who received 100–300 mg IV iron). There is no clear effect on milk production. Since iron is naturally present in milk, incidental increases seem well tolerated. If needed, IV iron can be used during breastfeeding. Still, consider benefits of breastfeeding and the mother’s anemia.\u003c\/p\u003e\n\u003ch2\u003ePediatrics:\u003c\/h2\u003e\n\u003cp\u003eSee “Dosage” above. IMS labels note that initial treatment safety\/efficacy in children (\u0026lt;2 years) is not established. Only maintenance doses (with ESAs in CKD) have been formally studied in children ≥2 years Premature infants or very young children should generally avoid IV iron unless in exceptional cases (due to possible risk of gut necrosis.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eGeriatrics:\u003c\/strong\u003e Trials included many elderly patients, and no age-specific toxicity was noted. Dosing adjustments are usually not needed based on age alone, but monitor for comorbidities (renal, cardiovascular) that could increase sensitivity.\u003c\/p\u003e\n\u003ch2\u003eDrug Interactions:\u003c\/h2\u003e\n\u003cp\u003eBecause iron sucrose is given IV, it bypasses gut absorption. Thus \u003cstrong\u003eoral drug interactions\u003c\/strong\u003e (e.g. diminished absorption of oral quinolone antibiotics or levodopa) are not relevant. However, do \u003cstrong\u003enot mix\u003c\/strong\u003e iron sucrose in the same IV line with other drugs (especially those containing sulfhydryl or alkaline reduce valency) because the iron complex can bind or precipitate. There are no major CYP-related interactions. In general, treatment can proceed without altering other medications, but monitor for additive blood pressure effects if the patient is on antihypertensives or anesthesia.\u003c\/p\u003e\n\u003ch2\u003eOverdose:\u003c\/h2\u003e\n\u003cp\u003eAcute overdose of IV iron (beyond recommended doses) can lead to iron toxicity: severe hypotension, metabolic acidosis, gastrointestinal bleeding, and organ failure. There are no specific antidotes, but deferoxamine (an iron chelator) can be used if severe iron poisoning is suspected. Chronic overdose (from repeated excess dosing) leads to iron overload as above. Always adhere to recommended dosing regimens and lab monitoring to avoid this.\u003c\/p\u003e\n\u003ch2\u003eHow Supplied and Storage:\u003c\/h2\u003e\n\u003cp\u003eIMS iron sucrose injection comes in single-dose vials (2.5 mL, 5 mL, 10 mL), each containing the specified mg of iron at 20 mg\/mL. Store at room temperature (68–77°F, protect from freezing). Use sterile technique. After withdrawing a dose, administer promptly or refrigerate if needed (the label notes stability for several days if refrigerated, but practice is to use immediately). Discard any unused portion from the vial.\u003c\/p\u003e\n\u003ch2\u003ePatient Counseling:\u003c\/h2\u003e\n\u003cp\u003ePatients should be told this medication is for IV use only. They should expect the infusion to be given slowly, and to let staff know if they feel itchy, short of breath, dizzy, or have pain during the infusion. Advise them to report fever, muscle or joint pain, or any unusual symptoms afterwards. Emphasize importance of follow-up blood tests (hemoglobin, ferritin) to gauge response. Remind them not to take oral iron supplements (like ferrous sulfate) shortly before or after IV dosing unless instructed, since iron sucrose quickly replenishes stores. For nursing mothers, reassure that occasional IV iron exposure has not been shown to harm infants. Also counsel that stopping iron sucrose and seeking medical care is needed if symptoms worsen or if anemia symptoms (fatigue, pallor, dizziness) do not improve after treatment, since treatment of underlying cause may be needed.\u003c\/p\u003e\n\u003cp\u003eIron sucrose injection 20 mg\/mL (IMS) is an FDA-approved IV iron therapy for iron-deficiency anemia in CKD patients. It provides a reliable way to replenish iron stores when oral iron is insufficient or cannot be used. Proper use requires slow IV administration, monitoring for hypersensitivity, and periodic lab checks to avoid overload. When used as directed, it effectively improves anemia with generally good tolerance.\u003c\/p\u003e","brand":"International Medication Systems","offers":[{"title":"Default Title","offer_id":53791121113456,"sku":"76329-9200-01","price":259.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Iron-Sucrose-Injection-20-mg2_5-grams--International-Medication-Systems.jpg?v=1779195729"},{"product_id":"iron-sucrose-injection-20-mg-ml-single-dose-vial-5-ml-x-10-pack-rx","title":"Iron Sucrose Injection 20 mg\/mL SIngle-Dose Vial 10 mL x 5\/Pack (RX)","description":"\u003ch1\u003eIron Sucrose Injection (20 mg\/mL, 5 mL single-dose vial)\u003c\/h1\u003e\n\u003cp\u003eIron sucrose injection is an \u003cstrong\u003eintravenous iron replacement\u003c\/strong\u003e medication. Each single-use vial contains 100 mg elemental iron in 5 mL of solution (20 mg\/mL), provided as a sterile, brown aqueous solution of iron(III)-hydroxide in sucrose. The product is preservative-free (“contains no preservatives”) and must be used under medical supervision. The 5 mL vial delivers 100 mg of elemental iron; smaller (2.5 mL, 50 mg) and larger (10 mL, 200 mg) vials are also available. Iron sucrose is a prescription drug (e.g. Venofer® and generics) used primarily when oral iron cannot meet needs.\u003c\/p\u003e\n\u003ch2\u003eIndications\u003c\/h2\u003e\n\u003cp\u003eIron sucrose injection is approved for \u003cstrong\u003etreatment of iron‐deficiency anemia (IDA) in patients with chronic kidney disease (CKD)\u003c\/strong\u003e. This includes adults and children (≥2 years) on dialysis (hemodialysis or peritoneal) or not yet on dialysis. In CKD, patients often have ongoing iron losses and need rapid iron repletion, especially when on erythropoiesis‐stimulating agents (ESAs).\u003c\/p\u003e\n\u003cp\u003eAlthough not on FDA label, iron sucrose is frequently used off‐label for other severe IDA situations. For example, it may be given to patients with GI malabsorption (e.g. inflammatory bowel disease, celiac sprue, bariatric surgery), heavy menstrual bleeding, postpartum anemia, or chemotherapy‐induced anemia – essentially any case where oral iron is ineffective or not tolerated and rapid repletion is needed. In practice, clinical guidelines recommend considering IV iron for IDA if oral supplements fail or when correction is urgent. (Note: IV iron should not replace evaluation of underlying causes of anemia.)\u003c\/p\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003cp\u003eThe iron in this product is bound in a sucrose complex. When infused IV, the complex dissociates: free iron (Fe³⁺) binds to plasma transferrin and is transported to bone marrow and other tissues. There, iron is incorporated into hemoglobin of developing red cells. Any excess iron is stored (mainly in liver, spleen, marrow) for later use. Because iron sucrose bypasses the gut, it rapidly raises serum iron and allows immediate availability for erythropoiesis. It is especially useful when gastrointestinal absorption is inadequate.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePharmacokinetics:\u003c\/strong\u003e After infusion, serum iron and transferrin saturation (TSAT) rise quickly. (TSAT values remain elevated for about 24–48 hours, so levels should not be measured sooner than 2 days post-infusion.) Iron is gradually utilized or stored; the half-life is on the order of hours. The sucrose carrier is filtered by the kidneys (approximately 75% in 24 hours) and excreted.\u003c\/p\u003e\n\u003ch2\u003eDosage and Administration\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003ePreparation:\u003c\/strong\u003e Vials are for single use only (no preservatives), and any unused portion must be discarded. Inspect each vial before use; do not use if it is discolored or contains particulates. For infusion, iron sucrose may be used undiluted (IV push) or diluted in 0.9% sodium chloride. If diluting, use only saline and ensure a final concentration of 1–2 mg iron\/mL (i.e. dilute 100 mg in ≥50 mL saline). Do not mix with dextrose solutions, other drugs, or blood products in the same IV line.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAdministration:\u003c\/strong\u003e Iron sucrose must be given \u003cstrong\u003eintravenously\u003c\/strong\u003e only – never intramuscularly or orally. It should be administered slowly to reduce adverse reactions. For example, a 100 mg dose can be given by a 2–5 minute IV push or a 15-minute infusion (diluted in ≤100 mL saline). Larger doses (200–400 mg) are typically given as infusions: e.g. 200 mg over ~15 minutes, 300 mg over ~1.5 hours, 400 mg over ~2–2.5 hours. Blood pressure should be monitored, and staff should observe the patient during and for ≥30 minutes after each dose (since iron sucrose can cause hypotension and allergic reactions). Emergency medications (e.g. epinephrine) must be readily available.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTypical Regimens (Adults):\u003c\/strong\u003e The total iron needed depends on the hemoglobin\/iron deficit. In CKD, a common target is ~1000 mg total. For example:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHemodialysis (CKD-HD):\u003c\/strong\u003e 100 mg IV per dialysis session (2–3 times\/week) until total ~1000 mg. Each 100 mg is given as a slow push or short infusion.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNon-dialysis CKD (CKD-ND):\u003c\/strong\u003e 200 mg IV weekly for 5 doses (total 1000 mg) or 500 mg twice (2 weeks apart). A 200 mg dose can be infused over ~15 minutes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePeritoneal dialysis (CKD-PD):\u003c\/strong\u003e 300 mg IV on day 1 and day 5 or 15, then 400 mg on day 29 (total 1000 mg). The 300–400 mg doses are infused over longer times (1.5–2.5 hours).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMaintenance:\u003c\/strong\u003e After initial correction, ongoing low-dose iron (e.g. 100 mg monthly or as needed) may be given to maintain stores. Iron sucrose treatment can be repeated if iron deficiency recurs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003ePediatric Patients:\u003c\/strong\u003e Iron sucrose is \u003cstrong\u003enot studied for initial correction\u003c\/strong\u003e in young children. For pediatric CKD patients on ESAs (≥2 years old), maintenance dosing was 0.5–2 mg\/kg IV (max 100 mg) every 2–4 weeks, which maintained hemoglobin in the target range in clinical studies. (In those studies, ~50% of children on 0.5–2 mg\/kg maintained hemoglobin 10.5–14 g\/dL on EPO.) Iron sucrose has \u003cstrong\u003enot\u003c\/strong\u003e been studied in infants or children under 2 years. Use in very young children requires extreme caution (cases of intestinal injury have been reported). Children on peritoneal dialysis may follow similar regimens with appropriate dilution and monitoring.\u003c\/p\u003e\n\u003ch2\u003eContraindications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllergy:\u003c\/strong\u003e Do \u003cem\u003enot\u003c\/em\u003e give to anyone with a known hypersensitivity to iron sucrose or its components. Reactions to other parenteral iron products may also indicate risk.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIron overload:\u003c\/strong\u003e Do not administer if there is evidence of iron overload (e.g. hemochromatosis) or high iron stores (transferrin saturation \u0026gt;50%, ferritin \u0026gt;500–800 ng\/mL), as excess iron can deposit in organs. Patients should have documented iron deficiency before treatment.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWarnings and Precautions\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypersensitivity:\u003c\/strong\u003e Severe allergic or anaphylactic reactions can occur (though less frequently than with older iron dextrans). Monitor closely during and for 30+ minutes after infusion. Treat any signs of anaphylaxis immediately. Only administer when staff and resuscitation equipments are available. Patients with asthma or history of allergies may be at higher risk.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypotension:\u003c\/strong\u003e Rapid infusion can cause significant hypotension. Infuse slowly and monitor blood pressure. If hypotension or syncope occurs, stop infusion and take supportive measures (IV fluids, Trendelenburg position). In pregnancy, severe maternal hypotension could compromise the fetus.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIron overload:\u003c\/strong\u003e Because iron is not easily excreted, repeated large doses can lead to hemosiderosis. Regularly monitor hemoglobin, ferritin, and TSAT. Do not give further iron if ferritin\/TSAT indicate overload.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInfection:\u003c\/strong\u003e Iron can promote bacterial growth. Use with caution in patients with active infection. Some experts avoid IV iron in sepsis until infection is controlled.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdministration issues:\u003c\/strong\u003e Use only the recommended diluents and IV rates. Avoid mixing in the same IV line with incompatible drugs. (IV iron has no significant drug–drug interactions with oral agents since it bypasses the gut, but it should not be co-infused with incompatible IV medications.)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePost-injection observation:\u003c\/strong\u003e Patients should report any unusual symptoms (chest pain, difficulty breathing, severe headache, rash) during or shortly after the infusion.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSide Effects (Adverse Reactions)\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eCommon (≥2%):\u003c\/strong\u003e Gastrointestinal upset (nausea, vomiting, diarrhea, constipation), headache, dizziness, muscle cramps, arthralgia, hypotension (usually mild\/transient), hypertension, flushing, itching or rash, injection-site pain or discoloration, and fatigue. These symptoms are usually mild.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSerious:\u003c\/strong\u003e Rare cases of severe anaphylaxis or anaphylactoid reactions (shocks, convulsions) have been reported. Other rare events include chest pain, rapid heart rate, respiratory distress, thrombosis (of vascular access in dialysis), and electrolyte disturbances. Case reports exist of seizures or hematologic reactions in severe iron overload, but these are extremely uncommon.\u003c\/p\u003e\n\u003cp\u003eAny severe reaction (e.g. difficulty breathing, swelling, intense rash, severe hypotension) warrants immediate discontinuation and emergency care. All adverse events should be reported to the prescribing physician and FDA MedWatch.\u003c\/p\u003e\n\u003ch2\u003eSpecial Populations\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePregnancy:\u003c\/strong\u003e Category B. Studies where iron sucrose was given after the first trimester showed no increased risk of fetal abnormalities. First-trimester use has not been well studied. It is well recognized that untreated maternal IDA can cause poor outcomes (prematurity, low birth weight, postpartum complications), so correcting iron deficiency in pregnancy is important. If IV iron is needed (e.g. severe anemia, oral intolerance), it can be given after the first trimester with caution. Monitor both mother and fetus during infusion for any adverse signs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLactation:\u003c\/strong\u003e Iron sucrose is excreted in breast milk, but studies of 100–300 mg IV doses have \u003cstrong\u003enot reported any adverse effects in breastfed infants\u003c\/strong\u003e. No impact on milk production has been observed. Given the benefits of treating maternal anemia and the lack of reported harm to infants, IV iron sucrose is generally considered safe during breastfeeding. However, mothers should discuss risks\/benefits with their doctor.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePediatric:\u003c\/strong\u003e As above, use is limited. Not approved for infants \u0026lt;2 years. Use only if clearly indicated and with pediatric expertise; infants and toddlers are more vulnerable to iron toxicity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGeriatric:\u003c\/strong\u003e Clinical studies included many older adults with no unusual toxicity, so dosing does not need adjustment based on age alone. However, older patients may have comorbidities (heart disease, kidney insufficiency) that necessitate slower administration and careful monitoring.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eMonitoring\u003c\/h2\u003e\n\u003cp\u003eBefore and during therapy, monitor hemoglobin\/hematocrit, serum ferritin, and transferrin saturation (TSAT) to gauge response. Because IV iron acutely raises TSAT and serum iron, measure these at least 24–48 hours \u003cem\u003eafter\u003c\/em\u003e infusion. Do not re-dose iron if ferritin exceeds ~500–800 ng\/mL or TSAT \u0026gt;50%, to avoid overload. Regularly check for signs of anaphylaxis (especially on the first dose). Vital signs should be checked during and after each infusion.\u003c\/p\u003e\n\u003ch2\u003eStorage and Handling\u003c\/h2\u003e\n\u003cp\u003eStore the vials at controlled room temperature, 20–25 °C (68–77 °F); brief excursions to 15–30 °C are allowed. Protect from freezing and heat. Keep in the original carton to protect from light. After drawing a dose, administer promptly or store the syringe (prepared solution) refrigerated; used vials or syringes must be discarded if not used immediately.\u003c\/p\u003e\n\u003cp\u003eIron sucrose injection (20 mg\/mL, 5 mL vial) is an FDA-approved IV iron therapy for iron-deficiency anemia in CKD patients. It provides elemental iron (100 mg per vial) via a sucrose‐iron complex. When filled, it must be given intravenously under slow infusion with appropriate monitoring. It is typically used in hemodialysis and non-dialysis CKD (often 100–200 mg doses), and is also used off-label for other refractory IDA cases. Its common side effects include gastrointestinal upset and mild hypotension; rare but serious effects include hypersensitivity and iron overload. In pregnancy and lactation it is considered relatively safe, whereas infants require caution. Overall, with proper dosing and monitoring, iron sucrose is a generally well-tolerated and effective method to replenish iron stores when oral therapy is insufficient.\u003c\/p\u003e","brand":"International Medication Systems","offers":[{"title":"Default Title","offer_id":53791234851184,"sku":"76329-9201-01","price":625.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Iron-Sucrose-Injection-20-mg-5-ml--international-Medication-Systems-76329-9201-01.jpg?v=1779203595"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/collections\/Amphastar-Pharmaceuticals-Logo.jpg?v=1771005284","url":"https:\/\/www.mountainside-medical.com\/collections\/international-medication-systems.oembed?constraint=calcium-injection","provider":"Mountainside Medical","version":"1.0","type":"link"}