Lidocaine for Injection 2% Vial, 5 mL, by APP Pharma
Lidocaine for Injection 2% Vial by APP Pharmaceuticals is a sterile, single-dose vial used for intravenous use.
- Preservative Free
- Single dose Vial
- Sealed cap
Brand: APP Pharmaceuticals
Size: 5 mL
Lidocaine Hydrochloride Injection, USP intravenous for
cardiac arrhythmias, is a sterile, nonpyrogenic solution
prepared from lidocaine with the aid of hydrochloric acid
in Water for Injection.
Each mL contains: Lidocaine HCl 20 mg; Sodium
Chloride 6 mg; Water for Injection q.s. Hydrochloric acid
and/or sodium hydroxide may have been added for pH
adjustment (pH 5.0 to 7.0). The container is for single
use; solution contains no preservative.
Lidocaine hydrochloride exerts its antiarrhythmic effect
by raising the electrical stimulation threshold of the
ventricle during diastole. In usual therapeutic doses,
lidocaine hydrochloride produces no change in
myocardial contractility, systemic arterial pressure or
in absolute refractory period.
Onset of action is rapid after an intravenous bolus with
a duration of action of approximately 15 to 20 minutes.
Approximately 90% of an administered dose of
lidocaine hydrochloride is metabolized in the liver. The
remainder (10%) of the drug is excreted unchanged in
the urine. Pharmacokinetic data indicate reduced
elimination of lidocaine after prolonged (24 hours)
infusion with resultant prolongation of the half-life to
approximately three times that seen following a single
INDICATIONS AND USAGE:
Lidocaine Hydrochloride Injection, USP administered
intravenously is specifically indicated in the acute
management of 1) ventricular arrhythmias occurring
during cardiac manipulation such as cardiac surgery,
and 2) life-threatening arrhythmias, particularly those
which are ventricular in origin, such as those which occur
during acute myocardial infarction.
Buy Lidocaine for Injection 2% Vial, 5 mL, by APP Pharma online at Mountainside Medical Equipment.