{"title":"Naloxone Prefilled Syringes","description":"\u003cp\u003e\u003cstrong\u003eNaloxone Prefilled Syringes \u003c\/strong\u003eare essential, life-saving devices for the rapid emergency treatment of opioid overdose. These prefilled syringes deliver a precise naloxone dose, ensuring fast, reliable reversal of opioid toxicity, respiratory depression, and overdose symptoms. Designed for quick administration by healthcare professionals or first responders, naloxone prefilled syringes are vital for harm reduction, overdose prevention, opioid safety, and emergency medical preparedness, supporting improved public health outcomes.\u003c\/p\u003e","products":[{"product_id":"naloxone-injection-prefilled-syringe-opioid-antidote-2-ml","title":"Naloxone Prefilled Syringe for Injection 2mg Dose (Rx)","description":"\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003cstrong\u003eNaloxone prefilled syringe\u003c\/strong\u003e refers to a \u003cstrong\u003eready-to-use syringe that comes pre-loaded with naloxone solution\u003c\/strong\u003e, intended for quick administration during an \u003cstrong\u003eopioid overdose emergency\u003c\/strong\u003e. Naloxone itself is a \u003cstrong\u003emedication that rapidly reverses the effects of opioids\u003c\/strong\u003e (such as heroin, fentanyl, or prescription painkillers) by binding to opioid receptors and blocking or displacing the opioid molecules. This antidote can restore normal breathing in a person whose breathing has slowed or stopped due to an overdose.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cem\u003e\u003cstrong\u003eCurrent Expiration : October 2026\u003c\/strong\u003e\u003c\/em\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cstrong\u003e\u003c\/strong\u003e\u003cstrong\u003eUses:\u003c\/strong\u003e\n\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eLife-Saving Opioid Overdose Treatment\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eCrucial for Fentanyl, Heroin, Prescription Painkiller Overdose\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eRestores Normal Breathing Until Emergency Help Arrives\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003ePrevents Fatalities and Severe Brain Injury\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eIntegral Part of Harm Reduction and Public Health Programs\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eWhen we say “prefilled syringe,” it means the syringe is \u003cstrong\u003ealready filled by the manufacturer with a specific dose of naloxone\u003c\/strong\u003e, so a rescuer doesn’t have to draw up the medication from a vial. It’s essentially \u003cem\u003enaloxone in an injectable form, packaged for immediate use\u003c\/em\u003e. Prefilled syringes are designed to make naloxone administration simpler and faster for both medical professionals and everyday people who might be responding to an overdose.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey features of a Naloxone Prefilled Syringe:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003ePre-Measured Dose:\u003c\/strong\u003e The syringe contains a set amount of naloxone, often a standard dose such as \u003cstrong\u003e2 mg in 2 mL\u003c\/strong\u003e or \u003cstrong\u003e1 mg in 1 mL\u003c\/strong\u003e of solution (concentrations can vary by product). Because the dose is pre-measured, the user doesn’t need to worry about calculating or measuring the medication in the moment – they simply use the syringe as instructed. This reduces the chance of dosing errors and saves valuable time when responding to an overdose.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eAdministration Routes:\u003c\/strong\u003e A naloxone prefilled syringe is typically intended for \u003cstrong\u003einjection\u003c\/strong\u003e into a muscle (intramuscular, e.g., into the outer thigh or shoulder) or under the skin (subcutaneous), though in hospital settings it can be given intravenously. In community overdose kits, the most common use of a prefilled naloxone syringe is \u003cstrong\u003eintramuscular injection\u003c\/strong\u003e. The syringe often comes with a needle or the kit includes a separate needle that you attach. To use it, you would remove safety caps, insert the needle into the person’s thigh (through clothing if necessary), and push the plunger to inject the medication. Naloxone usually works within 2-3 minutes to start reversing respiratory depression.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eIntranasal Use with Adapter:\u003c\/strong\u003e Some naloxone prefilled syringes are also used for \u003cstrong\u003eintranasal administration\u003c\/strong\u003e (through the nose) by adding a special atomizer tip. In many community programs, naloxone is supplied as a \u003cstrong\u003eprefilled syringe (typically 2 mg of naloxone in 2 mL)\u003c\/strong\u003e plus a \u003cstrong\u003emucosal atomization device\u003c\/strong\u003e that attaches to the syringe. In an overdose, the responder twists the atomizer onto the syringe, then sprays half the dose up one nostril and half up the other. The liquid is atomized into a fine mist that is absorbed through the nasal lining. This method allows bystanders to give naloxone \u003cstrong\u003ewithout using a needle\u003c\/strong\u003e. (Note: More recently, single-step nasal spray devices like Narcan® have become popular, but the prefilled syringe + atomizer is still used in many kits because it’s cost-effective and easy to assemble.)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eEase of Use in Emergencies:\u003c\/strong\u003e The whole point of a prefilled syringe is to be \u003cstrong\u003equick and straightforward\u003c\/strong\u003e:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eThere’s \u003cstrong\u003eno need to draw medicine from a vial\u003c\/strong\u003e (which can be tricky in a high-stress situation).\u003c\/li\u003e\n\u003cli\u003eThe \u003cstrong\u003eplunger is ready to push\u003c\/strong\u003e and deliver the naloxone.\u003c\/li\u003e\n\u003cli\u003eSome products have clear markings and often even come with brief instructions in the kit. In some cases, the syringe might be a specially designed auto-injector (like the now-discontinued Evzio®, which would talk the user through the steps); but typically “prefilled syringe” refers to a more basic design that you operate manually.\u003c\/li\u003e\n\u003cli\u003eThese syringes are \u003cstrong\u003eportable\u003c\/strong\u003e and usually included in opioid overdose rescue kits distributed to opioid users, their friends\/family, first responders, and community organizations. They often have a shelf-life of a year or more and should be stored at room temperature (not extreme heat or freezing) and protected from light.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eExamples of Prefilled Naloxone Syringes:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eOne example is the \u003cstrong\u003e“needle-free” intranasal kit\u003c\/strong\u003e: a 2 mL prefilled naloxone syringe (concentration 1 mg\/mL) that is used with a nasal atomizer. Many public health programs have used this format.\u003c\/li\u003e\n\u003cli\u003eAnother example is \u003cstrong\u003eZIMHI™\u003c\/strong\u003e, a more recently approved product (in the U.S.) which is a \u003cstrong\u003eprefilled single-dose syringe intended for intramuscular injection\u003c\/strong\u003e, containing a 5 mg dose of naloxone in 0.5 mL. It’s designed for layperson use with minimal steps (pull off cap, inject into thigh muscle, push plunger). This provides a higher dose of naloxone for potent synthetic opioid overdoses.\u003c\/li\u003e\n\u003cli\u003eIn some countries, there are prefilled syringes with naloxone that come with standard luer-lock fittings, often used by medical personnel or included in first aid kits (for example, a 1 mL prefilled syringe with 1 mg naloxone HCl for hospital use, or a 2 mL syringe with 2 mg for community use).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eComparison to Other Naloxone Forms:\u003c\/strong\u003e Besides prefilled syringes, naloxone also comes in:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVials or ampoules\u003c\/strong\u003e (small bottles) which require drawing the medication into a syringe manually. This is common in hospitals and EMS but less convenient for untrained people.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNasal sprays\u003c\/strong\u003e (like Narcan® Nasal Spray or generic naloxone nasal spray) which are ready-to-use devices you spray into one nostril—these are easy to use but typically more expensive per dose.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAuto-injectors\u003c\/strong\u003e (like the Evzio® device, which was a talking injector pen with naloxone) – very user-friendly but costly; not as widely available now due to price issues.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe \u003cstrong\u003eprefilled syringe lies somewhat in between\u003c\/strong\u003e the basic vial method and the high-tech auto-injector – it’s relatively inexpensive and straightforward, requiring a little more user action than an autoinjector, but far less than drawing from a vial. Its big advantage is speed and simplicity when every second counts.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"--content-height: undefinedpx;\" class=\"g1ul0 _0ZozC\"\u003e\n\u003cdiv\u003e\n\u003cdiv class=\"mr-3 ml-1\"\u003e\n\u003cdiv class=\"IGO1V\"\u003e\n\u003cp\u003eA naloxone prefilled syringe is a \u003cstrong\u003elife-saving emergency medication device\u003c\/strong\u003e: it’s naloxone in a syringe that’s already filled to the correct dose, allowing rapid injection (often into a muscle) or nasal administration (with an adapter) to counteract opioid overdoses. It's a crucial tool in the effort to reduce fatal overdoses, designed to be user-friendly so that even non-medical individuals can administer naloxone quickly when someone’s life is at risk from opioids.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"International Medication Systems","offers":[{"title":"Default Title","offer_id":16709700164,"sku":"76329-3369-1","price":22.8,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Naloxone-Prefilled-Syringe-for-Injection-2-mL-by-International-Medication-Systems-3369.jpg?v=1722011251"},{"product_id":"2-pack-narcan-nasal-spray","title":"Narcan Nasal Spray 4 mg (2 Pack)","description":"\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003cstrong\u003eNarcan\u003c\/strong\u003e is the brand name for \u003cstrong\u003enaloxone\u003c\/strong\u003e, a life-saving medication used to rapidly reverse opioid overdoses. Narcan is most commonly available as a \u003cstrong\u003enasal spray\u003c\/strong\u003e or as an \u003cstrong\u003einjectable\u003c\/strong\u003e solution. It is an opioid antagonist, which means it quickly blocks the effects of opioids—including heroin, fentanyl, oxycodone, morphine, and hydrocodone—on the brain and restores normal breathing in a person who has overdosed.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003eHow to Use Narcan Nasal Spray\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003ePeel:\u003c\/strong\u003e Remove the Narcan nasal spray device from the packaging.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePlace:\u003c\/strong\u003e Tilt the person's head back and insert the nozzle into one nostril.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePress:\u003c\/strong\u003e Firmly press the plunger to release the dose.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCall emergency services (911)\u003c\/strong\u003e immediately after administration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRepeat if needed:\u003c\/strong\u003e If the person does not respond in 2–3 minutes, another dose may be given.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eHow Narcan Works\u003c\/h2\u003e\n\u003cp\u003eNarcan (naloxone) rapidly displaces opioids from their receptors in the brain. This immediately reverses the life-threatening depression of the central nervous system and respiratory system caused by opioids, allowing a person to breathe normally again.\u003c\/p\u003e\n\u003cp\u003eNarcan’s effects begin to work \u003cstrong\u003ewithin 2-3 minutes\u003c\/strong\u003e after administration in most cases. However, Narcan’s duration is \u003cstrong\u003eshort (typically 30 to 90 minutes)\u003c\/strong\u003e, and it may wear off before the opioids in the person’s system have fully cleared. This means that \u003cstrong\u003eoverdose symptoms can return\u003c\/strong\u003e after Narcan wears off if no further medical intervention is given. That’s why Narcan is seen as an immediate, temporary fix – it \u003cstrong\u003ebuys time until emergency medical help can take over\u003c\/strong\u003e. It’s crucial to \u003cstrong\u003ecall 911\u003c\/strong\u003e even after giving Narcan, because additional medical care or additional doses of Narcan may be needed.\u003c\/p\u003e\n\u003cp\u003eOne important note is that Narcan \u003cstrong\u003eonly works on opioid drugs\u003c\/strong\u003e. It has \u003cstrong\u003eno effect on someone who has not taken opioids\u003c\/strong\u003e, so using it on a person who turned out to faint for another reason won’t cause harm (some experts say, \u003cem\u003e“if in doubt, give Narcan – it won’t hurt if it’s not an opioid overdose”\u003c\/em\u003e). It also \u003cstrong\u003ewon’t reverse non-opioid overdoses\u003c\/strong\u003e like those from alcohol, benzodiazepines (e.g., Xanax or Valium), or stimulants. However, if those substances are mixed with opioids, Narcan will address the opioid part of the overdose.\u003c\/p\u003e\n\u003ch2\u003eWhen is Narcan Used?\u003c\/h2\u003e\n\u003cp\u003eNarcan is used:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eIn suspected or confirmed opioid overdose\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003eWhen someone shows signs of overdose such as:\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eSlow or no breathing\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eExtreme drowsiness or unresponsiveness\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eBlue or pale skin, lips, or nails\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003ePinpoint pupils\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003cstrong\u003eNarcan\u003c\/strong\u003e is the \u003cstrong\u003ebrand name for naloxone\u003c\/strong\u003e, a medication that \u003cstrong\u003erapidly reverses opioid overdose by blocking opioid effects.\u003c\/strong\u003e. It is a \u003cstrong\u003esafe, easy-to-use antidote\u003c\/strong\u003e – often given as a simple nasal spray – that can \u003cstrong\u003erestore breathing and consciousness within minutes\u003c\/strong\u003e when someone has overdosed on opioids. By displacing opioids from their receptors, Narcan \u003cstrong\u003erevives the individual and buys time\u003c\/strong\u003e until emergency medical care can take over. It has become a cornerstone of emergency response in the opioid epidemic, carried by first responders and community members alike. If administered promptly, Narcan \u003cstrong\u003ecan literally bring someone back from the brink of death\u003c\/strong\u003e, which is why expanding access to this drug has been a major public health effort. Remember: after using Narcan, it’s vital to call 911 and get further medical help, because Narcan’s effect can wear off and professional evaluation is needed. But without a doubt, \u003cstrong\u003eNarcan is a critical, life-saving tool\u003c\/strong\u003e in preventing opioid overdose fatalities – a medicine that truly can mean the difference between life and death in an overdose situation\u003c\/span\u003e.\u003c\/p\u003e","brand":"Emergent Devices Inc","offers":[{"title":"Default Title","offer_id":12128283164744,"sku":"30369547627004","price":49.9,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/narcan_Nasal_Spray_OTC_243d34f1-a272-447a-9ab6-8ea7c4ad09e3.jpg?v=1695737082"},{"product_id":"kloxxado-8-mg-nasal-spray","title":"Kloxxado Naloxone Nasal Spray 8 mg x 2 Doses Per Box (Rx)","description":"\u003cp\u003eKloxxado Naloxone Nasal Spray 8 mg is used for the urgent treatment of opioid overdoses. This high-dose formulation delivers naloxone through a nasal spray to rapidly counteract life-threatening effects like respiratory depression. Designed for increased potency, Kloxxado quickly restores normal breathing in individuals exposed to opioid overdose, making it vital for emergency responders, healthcare providers, and laypersons. It enhances the likelihood of survival during critical overdose situations, contributing significantly to public health interventions aimed at managing the opioid crisis.\u003c\/p\u003e\n\u003cp\u003eKloxxado Naloxone Nasal Spray 8 mg by Hikma Specialty USA is an essential emergency medication designed to counteract opioid overdoses. This high-potency nasal spray delivers a swift, life-saving intervention in critical situations, making it a vital tool in the battle against the opioid crisis. Packaged in a convenient two-dose per box configuration, Kloxxado offers an easily accessible and user-friendly method for reversing the effects of opioid overdose, empowering non-medical personnel and first responders with the ability to act decisively when every second counts.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details and Features:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDosage: \u003c\/strong\u003eEach box contains two single-use nasal spray devices, each delivering an 8 mg dose of Naloxone.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrength: \u003c\/strong\u003e8 mg per spray, providing a higher dosage suitable for more severe overdoses or situations where lower strength doses are inadequate.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Nasal spray formulation allows for non-invasive, quick administration directly to the nasal mucosa. \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePackaging: \u003c\/strong\u003eEach device is individually packaged for safe and hygienic use.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage: \u003c\/strong\u003e The spray is stable at room temperature and can be stored in first-aid kits, medical cabinets, and emergency care settings.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAccessibility:\u003c\/strong\u003e No assembly is required; ready-to-use with no priming necessary.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMechanism of Action:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNaloxone, the active ingredient in Kloxxado, is an opioid antagonist that binds to the same receptor sites in the brain targeted by opioids. By doing so, it effectively displaces opioids, reversing their depressive effects on the nervous and respiratory systems, thus quickly restoring normal respiration and alertness in individuals experiencing an overdose.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for Use:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e1.\u003c\/strong\u003e Identify the person suspected of an opioid overdose. Signs include severe drowsiness, slow breathing, or unresponsiveness.\u003cbr\u003e\u003cstrong\u003e2. \u003c\/strong\u003eLay the person on their back to administer the spray.\u003cbr\u003e\u003cstrong\u003e3.\u003c\/strong\u003e Hold the device with your thumb on the bottom of the plunger and two fingers on the nozzle.\u003cbr\u003e\u003cstrong\u003e4. \u003c\/strong\u003eInsert the tip of the nozzle into one nostril until your fingers touch the bottom of the patient's nose.\u003cbr\u003e\u003cstrong\u003e5. \u003c\/strong\u003e Push the plunger firmly to release the dose into the nostril.\u003cbr\u003e\u003cstrong\u003e6.\u003c\/strong\u003e Call 911 immediately after administration, even if the patient revives, as further medical assessment is essential.\u003cbr\u003e\u003cstrong\u003e7. \u003c\/strong\u003eStay with the patient and await emergency services, administering the second dose in the other nostril after 2-3 minutes if there's no improvement.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWarnings:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eKloxxado is intended strictly for emergency intervention in opioid overdose; it is not a substitute for professional medical care.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eDo not use in patients known to be allergic to naloxone.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eSeek immediate medical help after administration as effects are temporary, and symptoms may return.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eMonitor the patient post-administration for signs of continued overdose or withdrawal symptoms.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eUse cautiously in pregnant individuals; although reversing an overdose takes precedence, potential risks should be considered.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eSide Effects:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCommon effects:\u003c\/strong\u003e Nasal discomfort, headache, increased blood pressure, hot flashes, or dry mouth.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWithdrawal symptoms:\u003c\/strong\u003e Irritability, body aches, sweating, shivering, teary eyes, or a runny nose if the patient is opioid-dependent.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSevere Reactions:\u003c\/strong\u003e Rarely, intense agitation or aggressive behavior. Seek physician guidance on managing these reactions in overdose contexts.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eKloxxado Naloxone Nasal Spray 8 mg is a crucial intervention tool, offering robust and reliable support in opioid overdose scenarios. Always follow up its use with professional medical care to ensure comprehensive treatment and monitoring.\u003c\/p\u003e","brand":"Hikma Specialty USA","offers":[{"title":"Default Title","offer_id":39549188898888,"sku":"59467-0679-01","price":169.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/products\/Nasal-Spray-2-dose.jpg?v=1681319117"},{"product_id":"sandoz-naloxone-hcl-4-mg-nasal-spray-blister-package-0-1-ml-2-doses","title":"Naloxone 4 mg Nasal Spray Blister Package 0.1 mL (2 Doses) by Sandoz","description":"\u003cp\u003eSandoz Naloxone 4 mg Nasal Spray is a prescription medication used to temporarily reverse the effects of opioid overdose. The nasal spray contains 4 mg of naloxone, which is a medication that can quickly counteract the life-threatening effects of opioid overdose, such as slowed or stopped breathing. This blister package contains one 0.1 mL spray, which is the recommended dose for adults and pediatric patients weighing more than 40 kg. This packaging is designed to provide a convenient and easy-to-use method for administering the medication in emergency situations.\u003c\/p\u003e\n\u003cp\u003eNaloxone HCl Nasal Spray is indicated for the emergency treatment of known or suspected opioid overdose, as manifested by respiratory and\/or central nervous system depression.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eNaloxone HCl Nasal Spray 4 mg is supplied as Carton containing two (2) blister packages (NDC 0781-7176-12) each with a single spray device.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003ePreservative Free\u003c\/p\u003e\n\u003cp\u003eSize: 4 mg \/ 0.1 mL x 2 doses\u003c\/p\u003e","brand":"Sandoz","offers":[{"title":"Default Title","offer_id":39549450944584,"sku":"1205311","price":99.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/products\/Sandoz-Naloxone-HCl-4-mg-Nasal-Spray-Blister-Package.jpg?v=1661881657"},{"product_id":"eugia-naloxone-hydrochloride-for-injection-pre-filled-syringes-2-ml-x-10-syringes","title":"Naloxone Hydrochloride for Injection Pre-Filled Syringes 2 mL x 10 Syringes","description":"\u003cp\u003eEugia Naloxone Hydrochloride for Injection Pre-Filled Syringes 2 mL x 10 Syringes. NDC: 55150-0345-10. Naloxone injection is used for emergency treatment of an opioid overdose or a possible overdose. It will temporarily reverse the effects of an opioid medicine.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eTherapeutic Class: Opioid Antagonist\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eReference Listed Drug: Narcan\u003csup\u003e®\u003c\/sup\u003e Injection\u003c\/p\u003e\n\u003cp\u003eSize: 2 mL\u003c\/p\u003e\n\u003cp\u003eCount: 10 Prefilled Syringes\u003c\/p\u003e\n\u003cp\u003eGluten Free, Latex Free \u0026amp; Preservative Free\u003c\/p\u003e\n\u003ch4\u003eStorage Requirements:\u003c\/h4\u003e\n\u003cp\u003eStore at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature].\u003c\/p\u003e","brand":"Eugia US","offers":[{"title":"Default Title","offer_id":39777801502792,"sku":"55150-0345-10","price":499.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/products\/Eugia-Naloxone-Hydrochloride-for-Injection-Pre-Filled-Syringes-2-mL-x-10-Syringes.jpg?v=1673616913"},{"product_id":"dr-reddys-naloxone-hcl-for-injection-2-mg-ml-prefilled-syringe-2ml-10-per-box","title":"Naloxone HCl for Injection 1 mg\/mL Prefilled Syringe 2 mL 10 Per Box by Dr Reddys  (RX)","description":"\u003cp\u003eDr Reddys Laboratories Naloxone HCl for Injection 1 mg\/mL Prefilled Syringe 2mL 10 Per Box. NDC: 43598-0750-58 for intravenous, intramuscular or subcutaneous use as an Opioid Antagonist.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eNaloxone hydrochloride injection is indicated for the complete or partial reversal of opioid depression, including respiratory depression, induced by natural and synthetic opioids, including propoxyphene, methadone and certain mixed agonist-antagonist analgesics: nalbuphine, pentazocine, butorphanol and cyclazocine. Naloxone hydrochloride is also indicated for diagnosis of suspected or known acute opioid overdosage.\u003c\/p\u003e\n\u003cp\u003eBrand: Dr Reddys Laboratories\u003c\/p\u003e\n\u003cp\u003eNDC: 43598-0750-58\u003c\/p\u003e\n\u003cp\u003eUPC: 343598-750583\u003c\/p\u003e\n\u003cp\u003eSize: 1 mg\/mL Prefilled Syringe 2mL\u003c\/p\u003e\n\u003cp\u003ePreservative Free\u003c\/p\u003e","brand":"Dr Reddys Laboratories","offers":[{"title":"Default Title","offer_id":39777867759688,"sku":"43598-0750-58","price":539.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/products\/Dr-Reddys-Naloxone-HCl-for-Injection-1-mg-mL-Prefilled-Syringe-2mL-10-Per-Box.jpg?v=1673620992"},{"product_id":"mylan-naloxone-hydrochloride-injection-2-mg-2-ml-1-mg-ml-single-dose-prefilled-syringe-2-ml","title":"Naloxone Hydrochloride Injection 2 mg\/2 mL (1 mg\/mL) Single-Dose Prefilled Syringe 2 mL","description":"\u003cp\u003eMylan Naloxone Hydrochloride Injection 2 mg\/2 mL (1 mg\/mL) Single-Dose Prefilled Syringe 2 mL is a prescription medication used for emergency treatment of known or suspected opioid overdose or life-threatening opioid overdose. It delivers a single dose of naloxone hydrochloride, a medication that can reverse the effects of opioids and restore breathing in someone who may have overdosed on them. The prefilled syringe is ready to use and includes instructions for administration. It should only be used as directed by a healthcare provider or in accordance with state and local guidelines for layperson use.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eNaloxone Hydrochloride Injection, USP is a sterile, single-dose 2 mg\/2 mL (1 mg\/mL) Prefilled syringe with a 21-Gauge, 1½ Inch Needle. NDC: 67457-0992-02.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eFor intravenous, Intramuscular or Subcutaneous Use \/ An Opioid Antagonist\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSingle Dose, do not reuse or resterilize.\u003c\/li\u003e\n\u003cli\u003eSterile\u003c\/li\u003e\n\u003cli\u003eEach Carton Contains: One 2 mL Single-Dose Prefilled Syringe with One 21-Gauge, 1½ Inch Needle.\u003c\/li\u003e\n\u003cli\u003eRx only\u003c\/li\u003e\n\u003cli\u003eNDC: 67457-0992-02\u003c\/li\u003e\n\u003cli\u003eBrand: Mylan Institutional\u003c\/li\u003e\n\u003cli\u003eSize: 2 mL Single-Dose Disposable Prefilled Syringe\u003c\/li\u003e\n\u003cli\u003eCount: 1\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Mylan Institutional","offers":[{"title":"Default Title","offer_id":39778059157576,"sku":"67457-0992-02","price":58.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Mylan-Naloxone-Hydrochloride-Injection-2-mg-Prefilled-Syringe.jpg?v=1762875489"},{"product_id":"zimhi-autoinjector-prefilled-syringe-for-injection-2-pack","title":"ZIMHI Autoinjector Naloxone Hydrochloride Prefilled Syringe for Injection, 2-Pack (Rx)","description":"\u003cp\u003eZIMHI Autoinjector Naloxone Hydrochloride Prefilled Syringe for Injection, 2-Pack. NDC: 78670-0140-02 Manufactured by \u003cspan class=\"ILfuVd\" data-mce-fragment=\"1\" lang=\"en\"\u003e\u003cspan class=\"hgKElc\" data-mce-fragment=\"1\"\u003eAdamis Pharmaceuticals\u003c\/span\u003e\u003c\/span\u003e.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eZIMHI is an opioid antagonist indicated for the emergency treatment of an opioid overdose, as manifested by respiratory and\/or central nervous system depression in adult and pediatric patients. ZIMHI is intended for immediate administration as emergency therapy in settings where opioids may be present.\u003c\/p\u003e\n\u003cp\u003eBrand: \u003cspan class=\"ILfuVd\" data-mce-fragment=\"1\" lang=\"en\"\u003e\u003cspan class=\"hgKElc\" data-mce-fragment=\"1\"\u003eAdamis Pharmaceuticals\u003c\/span\u003e\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"ILfuVd\" data-mce-fragment=\"1\" lang=\"en\"\u003e\u003cspan class=\"hgKElc\" data-mce-fragment=\"1\"\u003eNDC: 78670-0140-02\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"ILfuVd\" data-mce-fragment=\"1\" lang=\"en\"\u003e\u003cspan class=\"hgKElc\" data-mce-fragment=\"1\"\u003eUPC: 378670-140020\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp class=\"First\"\u003e\u003cstrong\u003e\u003cspan class=\"Bold\"\u003ePre-filled syringe\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"Bold\"\u003eUse ZIMHI for known or suspected opioid overdose in adults and children.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"Bold\"\u003eZIMHI is intended to be administered by people 12 years of age or older.\u003c\/span\u003e Younger children or those with limited hand strength may find the device difficult to use.\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"Bold\"\u003eRead this Instructions for Use carefully before you use this product.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eBefore you need to use your ZIMHI syringe make sure your healthcare provider shows you the right way to use it. Parents, caregivers, and others who may be in a position to administer ZIMHI should also understand how to use it. If you have questions, ask your healthcare provider.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan class=\"Bold\"\u003eGet Ready to Use ZIMHI\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eZIMHI works like a standard pre-filled syringe.\u003c\/p\u003e\n\u003cdiv class=\"Figure\"\u003e\u003cimg alt=\"Image\" src=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/image.cfm?name=zimhi-07.jpg\u0026amp;setid=52e49022-9172-4da3-ba83-5995cacca9fb\"\u003e\u003c\/div\u003e\n\u003cp\u003eZIMHI is injected downwards, into the middle of the outer thigh, (as shown), through clothing if needed.\u003c\/p\u003e\n\u003cdiv class=\"Figure\"\u003e\u003cimg alt=\"Image\" src=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/image.cfm?name=zimhi-08.jpg\u0026amp;setid=52e49022-9172-4da3-ba83-5995cacca9fb\"\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cspan class=\"Bold\"\u003eReady to Use ZIMHI\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg alt=\"Image\" src=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/image.cfm?name=zimhi-09.jpg\u0026amp;setid=52e49022-9172-4da3-ba83-5995cacca9fb\"\u003e\u003c\/p\u003e\n\u003cp\u003ePlace the patient on their back.\u003c\/p\u003e\n\u003cp\u003eWhen ready to inject, pull off cap to expose needle.\u003c\/p\u003e\n\u003cp\u003e\u003cimg alt=\"Image\" src=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/image.cfm?name=zimhi-10.jpg\u0026amp;setid=52e49022-9172-4da3-ba83-5995cacca9fb\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"Bold\"\u003eDo not put finger on top of the device.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eIn children under the age of 1 year old, pinch the thigh muscle while administering the dose.\u003c\/p\u003e\n\u003cp\u003eHold ZIMHI by finger grips only and slowly insert the needle into the thigh.\u003c\/p\u003e\n\u003cdiv class=\"Figure\"\u003e\u003cimg alt=\"Image\" src=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/image.cfm?name=zimhi-11.jpg\u0026amp;setid=52e49022-9172-4da3-ba83-5995cacca9fb\"\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cimg alt=\"Image\" src=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/image.cfm?name=zimhi-12.jpg\u0026amp;setid=52e49022-9172-4da3-ba83-5995cacca9fb\"\u003e\u003c\/p\u003e\n\u003cp\u003eAfter needle is in thigh: Push the plunger all the way down until it \u003cspan class=\"Bold\"\u003eclicks\u003c\/span\u003e and hold for 2 seconds.\u003c\/p\u003e\n\u003cdiv class=\"Figure\"\u003e\u003cimg alt=\"Image\" src=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/image.cfm?name=zimhi-13.jpg\u0026amp;setid=52e49022-9172-4da3-ba83-5995cacca9fb\"\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cimg alt=\"Image\" src=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/image.cfm?name=zimhi-14.jpg\u0026amp;setid=52e49022-9172-4da3-ba83-5995cacca9fb\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"Bold\"\u003eAfter Use\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eRight after the injection, using one hand with fingers behind the needle, slide the safety guard over the needle. Do not use two hands to activate the safety guard. Put the used syringe into the blue case and close the case.\u003c\/p\u003e\n\u003cp\u003e\u003cimg alt=\"Image\" src=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/image.cfm?name=zimhi-15.jpg\u0026amp;setid=52e49022-9172-4da3-ba83-5995cacca9fb\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg alt=\"Image\" src=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/image.cfm?name=zimhi-16.jpg\u0026amp;setid=52e49022-9172-4da3-ba83-5995cacca9fb\"\u003e\u003cspan class=\"Bold\"\u003eGet Help\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"Bold\"\u003eGet emergency medical help now\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"Figure\"\u003e\u003cimg alt=\"Image\" src=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/image.cfm?name=zimhi-17.jpg\u0026amp;setid=52e49022-9172-4da3-ba83-5995cacca9fb\"\u003e\u003c\/div\u003e\n\u003cp\u003eTell healthcare provider that you gave an injection of naloxone hydrochloride.\u003c\/p\u003e\n\u003cp\u003eTurn the patient on their side (recovery position) after giving ZIMHI.\u003c\/p\u003e\n\u003cdiv class=\"Figure\"\u003e\u003cimg alt=\"Image\" src=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/image.cfm?name=zimhi-18.jpg\u0026amp;setid=52e49022-9172-4da3-ba83-5995cacca9fb\"\u003e\u003c\/div\u003e\n\u003cp\u003eUse second syringe if needed\u003c\/p\u003e\n\u003cdiv class=\"Figure\"\u003e\u003cimg alt=\"Image\" src=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/image.cfm?name=zimhi-19.jpg\u0026amp;setid=52e49022-9172-4da3-ba83-5995cacca9fb\"\u003e\u003c\/div\u003e\n\u003cp\u003eYou may need a second ZIMHI syringe if symptoms continue or return.\u003c\/p\u003e\n\u003cp\u003eIf symptoms return after an injection with ZIMHI, an additional injection using another ZIMHI pre-filled syringe may be needed. Give additional injections using a new ZIMHI pre-filled syringe every 2 to 3 minutes and continue to closely watch the person until emergency help is received. Using ZIMHI does not take the place of emergency medical care.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan class=\"Bold\"\u003eAfter Use and Disposal\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul class=\"Disc\"\u003e\n\u003cli\u003eZIMHI is a single-dose pre-filled syringe that delivers a fixed dose of naloxone hydrochloride. The pre-filled syringe cannot be reused. It is normal for most of the medicine to remain in the syringe after the dose has been injected.\u003c\/li\u003e\n\u003cli\u003eThe correct dose has been injected if the plunger has been pushed all the way down and the solution window is at least partially blocked.\u003c\/li\u003e\n\u003cli\u003eTell the healthcare provider that you have received or administered an injection of naloxone hydrochloride. Show the healthcare provider where the injection was administered.\u003c\/li\u003e\n\u003cli\u003eGive your used ZIMHI syringe, contained in the blue case, to the healthcare provider for inspection and proper disposal.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan class=\"Bold\"\u003eFor more information see Patient Information sheet or ask your healthcare provider.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan class=\"Bold\"\u003eHow to Store\u003c\/span\u003e \u003c\/strong\u003e— Keep ZIMHI in its plastic case nearby and ready for use at all times.\u003c\/p\u003e\n\u003cul class=\"Disc\"\u003e\n\u003cli\u003eStore at controlled room temperature, between 68°F to 77°F (20°C to 25°C). \u003cspan class=\"Bold\"\u003eDo not\u003c\/span\u003e expose to extreme cold or heat. For example, \u003cspan class=\"Bold\"\u003edo not\u003c\/span\u003e store in your vehicle's glove box and \u003cspan class=\"Bold\"\u003edo not\u003c\/span\u003e store in the refrigerator or freezer.\u003c\/li\u003e\n\u003cli\u003eStore the ZIMHI syringe in its closed plastic case to protect from light.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Adamis Pharmaceuticals","offers":[{"title":"Default Title","offer_id":39778081013832,"sku":"78670-0140-02","price":179.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/products\/ZIMHI.jpg?v=1681321934"},{"product_id":"naloxone-injection-cartridge-with-luer-lock","title":"Naloxone Hydrochloride Injection 0.4 mg Prefilled Syringes Carpuject Cartridge with Luer Lock, 10\/Box","description":"\u003cp\u003eNaloxone Hydrochloride Injection 0.4 mg Prefilled Syringes are used for the emergency treatment of opioid overdoses. Naloxone rapidly reverses the effects of opioids, such as respiratory depression, sedation, and loss of consciousness, by displacing opioids from their receptors in the brain. It is a critical intervention in preventing fatal overdose outcomes. Medical personnel, as well as trained laypersons, commonly use these prefilled syringes due to their ease of administration. Naloxone acts quickly, but emergency medical attention is still required after administration, as it is a temporary solution.\u003c\/p\u003e\n\u003cp\u003ePfizer Injectables presents Naloxone Hydrochloride Injection, a life-saving medication designed for rapid intervention in cases of opioid overdose. Offered in convenient 0.4 mg prefilled syringes within the Carpuject Cartridge system with Luer Lock, this product is engineered for precision and efficiency, ensuring swift action in critical situations. Boxed in sets of 10, it is an essential tool for emergency responders and healthcare providers, delivering an opioid antagonist with reliability and ease of use.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details and Features:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eActive Ingredient:\u003c\/strong\u003e Each prefilled syringe contains 0.4 mg of Naloxone Hydrochloride, a potent opioid antagonist used to counteract the life-threatening effects of opioid overdose.\u003cbr\u003e\u003cstrong\u003eCarpuject Cartridge System:\u003c\/strong\u003e The prefilled syringes are part of the Carpuject Cartridge system, equipped with a Luer Lock to ensure secure and straightforward administration in high-pressure scenarios.\u003cbr\u003e\u003cstrong\u003ePackaging: \u003c\/strong\u003eAvailable in boxes of 10 syringes, prepared for quick accessibility to support emergency interventions.\u003cbr\u003e\u003cstrong\u003eIndications:\u003c\/strong\u003e Specifically designed for rapid reversal of opioid effects, including respiratory depression, sedation, and hypotension. Suitable for use in both pre-hospital and in-hospital settings.\u003cbr\u003e\u003cstrong\u003eReliability:\u003c\/strong\u003e Manufactured by Pfizer, a leader in pharmaceutical solutions, ensuring the highest standards of safety, quality, and effectiveness in acute care.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanism of Action:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNaloxone Hydrochloride functions as an opioid receptor antagonist. It binds to opioid receptors in the central nervous system, displacing opioids and reversing their effects, particularly the dangerous respiratory depression associated with overdose. This alleviates symptoms and restores normal respiratory function without producing significant agonist effects, ensuring safety across different patient populations.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWarnings:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOpioid Dependency:\u003c\/strong\u003e Excessive unusual doses in opioid-dependent patients may precipitate acute withdrawal symptoms. Administration requires monitoring and careful titration.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiovascular Concerns:\u003c\/strong\u003e Use cautiously in patients with pre-existing heart conditions or electrolyte imbalances, as abrupt reversal may induce cardiac stress.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShort Duration of Action: \u003c\/strong\u003eThe effects of naloxone may be shorter than the opioids, necessitating repeated dosing or continuous monitoring to manage resedation.\u003cbr\u003e\u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypersensitivity:\u003c\/strong\u003e Do not use in patients with known hypersensitivity to naloxone or any formulation components.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eSide Effects:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eCommon side effects may include:\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNausea and vomiting\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eDiaphoresis\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eIncreased blood pressure and tachycardia\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eSerious side effects or situations necessitating immediate attention:\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSigns of acute opioid withdrawal in dependent individuals, including agitation, tremors, or convulsions.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eSevere cardiovascular symptoms, notably in those with a history of heart disease or irregular heartbeat.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eConclusion:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNaloxone Hydrochloride Injection by Pfizer Injectables is a critical resource for combating opioid overdose, offering rapid antagonistic action through a reliable and user-friendly delivery system. With its precise dosing and trusted Pfizer quality, it stands as a crucial part of emergency medical care, empowering first responders and healthcare providers to save lives and mitigate the rising risks of opioid toxicity.\u003c\/p\u003e","brand":"Pfizer Injectables","offers":[{"title":"Default Title","offer_id":39811494707272,"sku":"0409-1782-69","price":299.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/products\/Pfizer-Nal-10.jpg?v=1681321696"},{"product_id":"rivive-naloxone-hcl-nasal-spray-3-mg-2-pack","title":"Rivive Naloxone HCl Nasal Spray 3 mg (2-Pack)","description":"\u003cp\u003eRivive Naloxone HCl Nasal Spray 3 mg is a over-the-counter medication used for emergency treatment of known or suspected opioid overdose. Rivive Naloxone contains the active ingredient naloxone hydrochloride, which works by blocking the effects of opioids and reversing the potentially life-threatening effects of an overdose. Rivive Naloxone nasal spray is administered by spraying it into the nostrils and is designed to be easy to use in emergency situations. It is recommended to always seek medical help after administering this medication. This product is only available with a prescription from a healthcare provider.\u003c\/p\u003e\n\u003cp\u003eRivive Naloxone HCl Nasal Spray 3 mg works by blocking the effects of opioids in the brain and reversing the respiratory depression caused by opioid overdose. Naloxone, the active ingredient in Rivive, is an opioid antagonist that binds to opioid receptors in the brain and displaces any opioids that may be present. This blocks the effects of the opioids and restores normal breathing in the person experiencing an overdose. The nasal spray delivery method allows for quick absorption into the bloodstream, making it an effective and potentially life-saving treatment for opioid overdose.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFeatures:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eEach Naloxone Hydrochloride Nasal Spray 3 mg device contains a single dose of 3 mg naloxone HCl in 0.1 mL solution\u003c\/li\u003e\n\u003cli\u003eThe Rivive box contains two OTC naloxone hydrocholoride 3 mg nasal spray devices; each packaged in a plastic blister pack with a copy of the directions (quick start guide) and sealed with a paperboard card.\u003c\/li\u003e\n\u003cli\u003eEach nasal spray device is labeled front and back with the RiVive trade name, lot number, and expiration date.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Greenwood Brands, LLC","offers":[{"title":"Default Title","offer_id":40376266817608,"sku":"82954-0100-01","price":64.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Rivive-Naloxone-HCl-Nasal-Spray-3-mg-by-Greenwood-Brands-82954-0100-01.jpg?v=1724069358"},{"product_id":"rextovy-naloxone-nasal-spray-4-mg-2-pack-rx","title":"Rextovy Naloxone Nasal Spray 4 mg (2-Pack) (RX)","description":"\u003cp\u003eRextovy Naloxone Nasal Spray 4 mg is a medication produced by International Medication Systems. It is a prescription nasal spray used to treat opioid overdose in adults, by reversing the effects of opioid drugs. Naloxone is the active ingredient in this medication, and it works by binding to opioid receptors in the brain and blocking the effects of opioids. This can help prevent respiratory failure and death in the case of an opioid overdose. It is important to note that Rextovy Naloxone Nasal Spray should not be used as a substitute for emergency medical care, and individuals who have received the medication should still seek immediate medical attention.\u003c\/p\u003e\n\u003cp\u003eRextovy Naloxone Nasal Spray is an emergency treatment designed to counter the life-threatening effects of opioid overdose. The 4 mg nasal spray is supplied in a convenient 2-pack, offering a ready-to-use, needle-free solution that delivers a potent dose of naloxone—a medication that rapidly reverses the effects of opioids. This product is essential for first responders, caregivers, or anyone who may encounter an opioid-induced respiratory emergency.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey Features:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePotent Rescue Solution:\u003c\/strong\u003e Each nasal spray delivers 4 mg of naloxone hydrochloride, providing an effective antidote in critical overdose situations.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUser-Friendly Design:\u003c\/strong\u003e Compact, easy-to-use device that requires no assembly, with simple instructions that make it accessible even for those without medical training.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmediate Action:\u003c\/strong\u003e Rapidly restores normal breathing and consciousness in individuals experiencing opioid overdoses, including those involving potent opioids like fentanyl.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTwo-Pack \u003c\/strong\u003eConvenience: Comes in a 2-pack for added security and preparedness, ensuring you have a backup readily available if needed.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOptional Paired Applicators\u003c\/strong\u003e: Separate packaging allows you to use one while keeping the other sterile and ready for future emergencies.\u003cstrong\u003e\u003c\/strong\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eUsage Instructions:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Preparation: Tear open the packaging to retrieve the nasal spray.\u003cbr\u003e2. Administration: Insert the nozzle into one nostril, pressing firmly on the applicator to release the dose.\u003cbr\u003e3. Wait and Observe: After administration, call emergency services and wait. If there is no response after 2-3 minutes, administer the second dose using the other nasal spray from the pack.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSafety Information:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Keep the product in its original packaging until needed. Store at room temperature, away from light and moisture.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWarnings:\u003c\/strong\u003e Be aware that naloxone may precipitate withdrawal symptoms in opioid-dependent individuals. Do not use the product if the packaging is damaged.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExpiration: \u003c\/strong\u003eEnsure to check the expiration date regularly and replace as needed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eWho Should Carry Rextovy Naloxone Nasal Spray:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFirst responders and healthcare providers.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eFamily members or caregivers of individuals with opioid prescriptions or at risk of overdose.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eCommunity organizations and drug treatment centers.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eTeachers, coaches, or leaders in environments where an opioid overdose risk exists.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eManufactured by:\u003c\/strong\u003e Rextovy Pharmaceuticals, known for their commitment to producing high-quality, life-saving medical products.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eRextovy Naloxone Nasal Spray is for emergency use only and is not a substitute for professional medical care. Always seek immediate medical attention following its administration.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTake Action, Save Lives:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEquip yourself with Rextovy Naloxone Nasal Spray and be prepared to act in the event of an opioid overdose. Your preparedness can make the difference between life and death.\u003c\/p\u003e","brand":"International Medication Systems","offers":[{"title":"Default Title","offer_id":40376290050120,"sku":"76329-3669-02","price":69.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Rextovy-Naloxone-Nasal-Spray-4-mg-International-Medication-Systems-76329-3669-02.jpg?v=1724071948"},{"product_id":"naloxone-hydrochloride-injection-prefilled-syringe-2-mg-per-2-ml-needle-not-included","title":"Naloxone Hydrochloride Injection Prefilled Syringe 2 mg Per 2 mL (Needle Not Included)  (Rx)","description":"\u003cp\u003eNaloxone Hydrochloride Injection Prefilled Syringe 2 mg per 2 mL by Endo USA is a life-saving medication designed to counteract the effects of opioid overdose swiftly. This prefilled syringe, without a needle, provides an immediate solution to reverse respiratory depression caused by opioid toxicity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details and Features:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eConcentration:\u003c\/strong\u003e 2 mg of Naloxone Hydrochloride per 2 mL, delivering a potent dose for rapid intervention.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrefilled Syringe:\u003c\/strong\u003e Ready-to-use format ensures quick administration in emergency scenarios.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeedle Not Included:\u003c\/strong\u003e Allows compatibility with various needle types as per medical preference.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReliable Manufacturer:\u003c\/strong\u003e Produced by Endo USA, a trusted name in pharmaceutical excellence.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePortable Design:\u003c\/strong\u003e Compact and easy to carry, making it ideal for emergency kits.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMechanism of Action:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNaloxone Hydrochloride acts as an opioid antagonist, binding to opioid receptors in the central nervous system. It displaces opioids from these receptors, rapidly reversing their effects, particularly respiratory depression, which is crucial in an overdose situation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for Use:\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003ePreparation:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAttach an appropriate needle to the prefilled syringe.\u003c\/li\u003e\n\u003cli\u003eEnsure aseptic conditions to maintain sterility.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eAdministration:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eInject intravenously, intramuscularly, or subcutaneously as per medical guidance.\u003c\/li\u003e\n\u003cli\u003eAdminister 2 mg (2 mL) initially, and repeat doses if necessary based on the patient’s response.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eMonitoring:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eContinuously monitor the patient's respiratory and neurological status post-administration.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cstrong\u003eSide Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eCommon Side Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNausea\u003c\/li\u003e\n\u003cli\u003eVomiting\u003c\/li\u003e\n\u003cli\u003eSweating\u003c\/li\u003e\n\u003cli\u003eTachycardia\u003c\/li\u003e\n\u003cli\u003eTremors\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eSevere Side Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHypotension or hypertension\u003c\/li\u003e\n\u003cli\u003eCardiac arrhythmias\u003c\/li\u003e\n\u003cli\u003eSeizures\u003c\/li\u003e\n\u003cli\u003ePulmonary edema\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSeek medical assistance if severe side effects occur.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWarnings:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMedical Supervision:\u003c\/strong\u003e Administer under the supervision of healthcare professionals experienced in managing opioid overdoses.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOpioid Withdrawal:\u003c\/strong\u003e Rapid reversal may cause acute withdrawal symptoms in opioid-dependent individuals.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMultiple Doses:\u003c\/strong\u003e Be prepared to administer additional doses if the response is inadequate or if there is a reoccurrence of symptoms.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store in a controlled room temperature environment away from light and moisture.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEmergency Protocols:\u003c\/strong\u003e Have resuscitative measures and supportive care readily available.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eNaloxone Hydrochloride Injection by Endo USA is an essential resource in combating opioid overdoses, providing healthcare professionals with a critical tool for emergency intervention and patient safety.\u003c\/p\u003e","brand":"Endo USA","offers":[{"title":"Default Title","offer_id":52184977473904,"sku":"42023-0224-01","price":32.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Naloxone-Hydrochloride-Injection-Prefilled-Syringe-2-mg.jpg?v=1744127223"},{"product_id":"naloxone-hcl-nasal-spray-4-mg-emergency-nasal-spray-2-pack","title":"Naloxone Nasal Spray 4 mg, Padagis (2-Pack)","description":"\u003ch1\u003eNaloxone Nasal Spray (Padagis® 4 mg, 2-Pack)\u003c\/h1\u003e\n\u003cp\u003eNaloxone nasal spray is an opioid \u003cem\u003eantagonist\u003c\/em\u003e used for emergency overdose rescue. Each single-dose nasal device contains 4 mg naloxone hydrochloride (in 0.1 mL solution) – the same strength as brand-name Narcan®. Naloxone works by quickly displacing opioids from brain receptors, \u003cstrong\u003erapidly reversing life-threatening respiratory and CNS depression\u003c\/strong\u003e. It typically restores normal breathing within minutes. Importantly, naloxone has \u003cstrong\u003eno effect on someone who hasn’t taken opioids\u003c\/strong\u003e (it is safe even if the person has no opioids in their system). Padagis® is a generic OTC brand of naloxone nasal spray; this 2-pack contains two separate pre-filled devices (two doses) for emergency use.\u003c\/p\u003e\n\u003ch2\u003eUses and Indications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eEmergency overdose reversal:\u003c\/strong\u003e Padagis 4 mg nasal spray is \u003cstrong\u003eindicated for known or suspected opioid overdose\u003c\/strong\u003e – especially if the person has slowed or stopped breathing or is unresponsive. It “revives” overdose victims by restoring breathing and consciousness.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFirst-aid use:\u003c\/strong\u003e It is intended for immediate administration as an emergency therapy by \u003cem\u003ebystanders or first responders\u003c\/em\u003e (family, friends, paramedics, etc.) when opioids are involved. After use, emergency medical care (911) \u003cstrong\u003emust still be sought immediately\u003c\/strong\u003e. Naloxone is \u003cem\u003enot\u003c\/em\u003e a substitute for full medical treatment; it’s a life-saving first aid that buys time until help arrives.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNo prescription needed:\u003c\/strong\u003e In the U.S., 4 mg naloxone nasal sprays (such as Padagis or Narcan) are now available over-the-counter without a prescription. They can be purchased online or at pharmacies, convenience stores, etc., ensuring broader access during the opioid epidemic.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eDosage and Administration\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSingle intranasal dose:\u003c\/strong\u003e To use Padagis, \u003cstrong\u003einsert one device’s nozzle into one nostril and press the plunger firmly\u003c\/strong\u003e. Each spray delivers a \u003cstrong\u003esingle 4 mg dose\u003c\/strong\u003e of naloxone. (The package has two devices; use one per administration.) The person should be laid on their back with head tilted, then squeeze the plunger as directed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRepeat if needed:\u003c\/strong\u003e If there is \u003cem\u003eno response\u003c\/em\u003e after about 2–3 minutes, use the second device to administer a second 4 mg spray (in the other nostril). Continue repeating every 2–3 minutes (with new devices) until the person begins breathing normally or emergency help arrives.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEmergency services:\u003c\/strong\u003e \u003cstrong\u003eAlways call 911 immediately\u003c\/strong\u003e when administering naloxone. Keep giving rescue breaths or CPR if needed while waiting for responders. Naloxone’s effects may wear off, so the patient must be monitored until professionals can take over.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eKey Points \u0026amp; Side Effects\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanism:\u003c\/strong\u003e Naloxone is a \u003cem\u003epure opioid antagonist\u003c\/em\u003e that “blocks” opioid receptors. It displaces opioids (heroin, fentanyl, oxycodone, etc.) and \u003cstrong\u003ereverses overdose symptoms.\u003c\/strong\u003e It has \u003cstrong\u003eno action if no opioids are present\u003c\/strong\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOnset\/duration:\u003c\/strong\u003e Onset of action is within minutes. However, naloxone’s duration (~30–90 min) may be shorter than some opioids, so rescue breathing or repeat dosing might be needed as noted above.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSafety:\u003c\/strong\u003e Naloxone is very safe; it \u003cem\u003ecannot\u003c\/em\u003e cause opioid overdose. Because it has no effect without opioids, giving it “just in case” is safe. It is recommended for anyone at risk of witnessing an overdose.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWithdrawal effects:\u003c\/strong\u003e In opioid-dependent individuals, naloxone \u003cstrong\u003eprecipitates acute withdrawal\u003c\/strong\u003e (which is uncomfortable but usually not life-threatening). Signs of withdrawal may include rapid heartbeat, sweating, nausea\/vomiting, shaking, body aches, or agitation. These are expected side effects of reversing the overdose and generally resolve on their own.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCommon side effects (after reversal):\u003c\/strong\u003e Reported mild adverse effects include \u003cem\u003eincreased blood pressure, headache, muscle aches, nasal dryness or congestion,\u003c\/em\u003e and tenderness. These are typically transient. No lasting harm comes from a single naloxone dose; managing the overdose is the priority.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllergies\/contraindications:\u003c\/strong\u003e A true allergy to naloxone is extremely rare. The \u003cstrong\u003eonly contraindication\u003c\/strong\u003e is known hypersensitivity to naloxone (or any ingredient). (No dose adjustment is needed for age, liver\/kidney function, etc., in an emergency.) If no opioids are involved, naloxone will simply have no effect.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003ePackage Details\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eContents:\u003c\/strong\u003e Each Padagis Nasal Spray 2-pack contains two \u003cstrong\u003esingle-use\u003c\/strong\u003e nasal spray devices (each pre-filled with 4 mg naloxone). The device is discardable after spraying (do \u003cem\u003enot\u003c\/em\u003e reuse).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIndication:\u003c\/strong\u003e The package labeling states: \u003cem\u003e“Emergency Treatment of Opioid Overdose”\u003c\/em\u003e. It may come with an instruction leaflet or quick-reference card. Follow all printed directions carefully.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at room temperature (typically 20–25 °C) in original packaging, away from light and moisture. Check the expiration date; replace expired kits.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Padagis US","offers":[{"title":"Default Title","offer_id":52242487181680,"sku":"45802-0578-84P","price":59.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Naloxone-HCl-Nasal-Spray-4-mg-by-Padagis-US.jpg?v=1746532598"},{"product_id":"naloxone-hydrochloride-injection-prefilled-syringes-0-4-mg-fresenius-kabi","title":"Naloxone Hydrochloride Injection Prefilled Syringes 0.4 mg per mL 1 mL x 24\/Box (RX)","description":"\u003cp\u003eNaloxone Hydrochloride Injection 0.4 mg\/mL in a ready‑to‑use prefilled syringe by Fresenius Kabi is a fast‑acting opioid antagonist for emergency reversal of opioid-induced respiratory and central nervous system depression. Designed for hospital, EMS, clinic, and other emergency settings, each sterile, preservative‑free 1 mL syringe delivers a single measured 0.4 mg dose. AP‑rated and with an 18‑month shelf life, this product provides reliable, on‑hand treatment to rapidly restore respiration in suspected opioid overdose.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat it is used for\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eEmergency reversal of opioid effects, including respiratory depression, sedation, and coma due to opioid overdose.\u003c\/li\u003e\n\u003cli\u003eImmediate treatment when opioid overdose is suspected (prescription opioids, heroin, fentanyl and other synthetic opioids).\u003c\/li\u003e\n\u003cli\u003eUse as part of resuscitative measures while arranging definitive medical care and monitoring.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDetails and features\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eStrength: 0.4 mg per mL; dose in each prefilled syringe = 0.4 mg.\u003c\/li\u003e\n\u003cli\u003ePrefilled, single‑dose syringe for rapid administration; reduces preparation time and dosing errors.\u003c\/li\u003e\n\u003cli\u003ePreservative‑free sterile formulation.\u003c\/li\u003e\n\u003cli\u003eAP‑rated (therapeutically equivalent generic).\u003c\/li\u003e\n\u003cli\u003ePack: 24 prefilled syringes per box — suitable for emergency carts, ambulances, clinics, and hospital units.\u003c\/li\u003e\n\u003cli\u003e18‑month shelf life for reliable storage readiness.\u003c\/li\u003e\n\u003cli\u003eClear labeling and visual inspection window to verify product prior to use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDirections and administration\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eInspect the syringe: check expiration date, ensure solution is clear and free of particulates, and confirm integrity of packaging\/syringe.\u003c\/li\u003e\n\u003cli\u003eFor injectable use only. Administer IV, IM or SC according to clinical situation and local protocols.\u003c\/li\u003e\n\u003cli\u003eIf administering intranasally, use only with an appropriate mucosal atomization device (not included); the product is formulated for parenteral use — follow your organization’s approved intranasal procedure if converting from injection to intranasal administration.\u003c\/li\u003e\n\u003cli\u003eProvide airway support, oxygen, and ventilation as needed; naloxone is an adjunct to supportive care.\u003c\/li\u003e\n\u003cli\u003eAfter initial response, monitor patient closely; recurrent respiratory depression may occur as the effect of some opioids outlasts naloxone.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDosage (typical dosing — follow local protocols and full prescribing information) Adults and adolescents:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eInitial: 0.4–2 mg IV, IM or SC. A common starting dose is 0.4 mg IV (one 0.4 mg syringe).\u003c\/li\u003e\n\u003cli\u003eIf no response in 2–3 minutes, repeat and escalate (e.g., 0.8 mg, 2 mg) as clinically indicated. Repeat dosing may be required; some synthetic opioids (e.g., fentanyl analogs) may require higher or repeated doses.\u003c\/li\u003e\n\u003cli\u003eIf IV access is not available, administer IM or SC and repeat as necessary.\u003c\/li\u003e\n\u003cli\u003eIn severe cases, titrate upward to restore adequate ventilation; some protocols allow escalation up to 10 mg or more if no response and opioid overdose strongly suspected.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eChildren and neonates:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNeonates: 0.01 mg\/kg IV\/IM (may repeat as needed). Note: naloxone is not routinely indicated in newborns with respiratory depression due to non‑opioid causes; follow neonatal resuscitation guidelines.\u003c\/li\u003e\n\u003cli\u003ePediatrics: Initial 0.01 mg\/kg IV\/IM (minimum doses vary by protocol); repeat dosing every 2–3 minutes as needed. For older children, some guidance suggests 0.1 mg\/kg (up to adult dosing) — follow pediatric protocols and consult prescribing information.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eContinuous infusion:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eIf recurrent or prolonged opioid effect is expected (e.g., long‑acting opioids), consider a continuous infusion: use total effective bolus dose over 1–2 hours as infusion; follow institutional policies and full prescribing information.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAllergies and precautions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eContraindication: Hypersensitivity to naloxone or any component of the formulation.\u003c\/li\u003e\n\u003cli\u003eUse caution in known opioid‑dependent patients — naloxone may precipitate acute opioid withdrawal (agitation, pain, vomiting, diarrhea, tachycardia, hypertension).\u003c\/li\u003e\n\u003cli\u003eUse with caution in patients with preexisting cardiovascular disease, seizure disorders, or other conditions where abrupt withdrawal or catecholamine surge could be harmful.\u003c\/li\u003e\n\u003cli\u003eNot effective for respiratory depression caused by non‑opioid agents (e.g., benzodiazepines, alcohol, certain sedative agents) — identify and treat underlying cause.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDrug interactions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNaloxone reverses the effects of opioid agonists and partial agonists (e.g., methadone, morphine, oxycodone, buprenorphine). It will antagonize analgesia and other opioid effects.\u003c\/li\u003e\n\u003cli\u003eMay precipitate withdrawal in patients receiving opioid maintenance therapy (methadone, buprenorphine).\u003c\/li\u003e\n\u003cli\u003eNo clinically significant direct pharmacokinetic interactions expected with most non‑opioid medications, but clinical responses can be altered by co‑intoxicants (stimulants, sedatives) and by the opioid’s potency\/duration.\u003c\/li\u003e\n\u003cli\u003eBe aware that reversal of opioids can unmask effects of other coingestants or medical conditions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSide effects and adverse reactions Common and expected events (often due to opioid withdrawal):\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNausea, vomiting\u003c\/li\u003e\n\u003cli\u003eAgitation, irritability\u003c\/li\u003e\n\u003cli\u003eSweating\u003c\/li\u003e\n\u003cli\u003eTremor\u003c\/li\u003e\n\u003cli\u003eTachycardia, hypertension\u003c\/li\u003e\n\u003cli\u003eBody aches, myalgias Serious but less common:\u003c\/li\u003e\n\u003cli\u003ePulmonary edema\u003c\/li\u003e\n\u003cli\u003eCardiac arrhythmias and myocardial ischemia (rare)\u003c\/li\u003e\n\u003cli\u003eSeizures\u003c\/li\u003e\n\u003cli\u003eSevere acute opioid withdrawal with associated complications\u003c\/li\u003e\n\u003cli\u003eRecurrent respiratory depression after initial reversal (due to longer‑acting opioids)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eWarnings\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eEmergency treatment only: naloxone is an immediate, temporary antagonist and not a substitute for comprehensive emergency care, airway management, and observation.\u003c\/li\u003e\n\u003cli\u003eRecurrent respiratory depression: Some opioids have longer duration than naloxone — continuous monitoring and repeated doses or infusion may be necessary; hospital observation is recommended.\u003c\/li\u003e\n\u003cli\u003ePrecipitated withdrawal: Use titration to the minimum effective dose to reverse respiratory depression without provoking severe withdrawal when appropriate (particularly in chronically opioid‑dependent patients).\u003c\/li\u003e\n\u003cli\u003eNot effective for non‑opioid poisoning: If opioid overdose is not the cause of respiratory depression, naloxone will not reverse non‑opioid depressant effects.\u003c\/li\u003e\n\u003cli\u003ePregnancy\/lactation: Use when maternal opioid toxicity poses immediate risk; naloxone crosses the placenta and can precipitate withdrawal in the fetus\/newborn. Treat neonates per neonatal resuscitation guidelines.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eStorage and handling\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eStore as labeled (manufacturer’s recommended temperature range). Keep in original packaging until use, protect from light, do not freeze.\u003c\/li\u003e\n\u003cli\u003eCheck expiration date; discard any syringe that is discolored or shows particulate matter.\u003c\/li\u003e\n\u003cli\u003eSingle‑dose syringe: do not reuse or resterilize.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eRegulatory and safety notes\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePrescription medication. Intended for professional and emergency use.\u003c\/li\u003e\n\u003cli\u003eAP‑rated generic (therapeutic equivalence) to the reference listed naloxone injectable product.\u003c\/li\u003e\n\u003cli\u003ePreservative‑free formulation; suitable for emergency parenteral use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eImportant: The dosing guidance above summarizes commonly used regimens and does not replace official prescribing information, local protocols, or clinical judgment. Always follow the full product prescribing information, institutional policies, and consult medical control or toxicology experts in complex cases.\u003c\/p\u003e","brand":"Fresenius Kabi","offers":[{"title":"Default Title","offer_id":52477197091184,"sku":"76045-0114-10","price":299.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Naloxone-Prefilled-Syringe-0_4-Fresenius-Karbi.jpg?v=1754999942"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/collections\/Naloxone_Prefilled_Syringes.jpg?v=1728923449","url":"https:\/\/www.mountainside-medical.com\/collections\/naloxone-prefilled-syringes\/naloxone-hydrochloride-injection.oembed","provider":"Mountainside Medical","version":"1.0","type":"link"}