{"title":"Naltrexone Hydrochloride","description":"\u003ch1\u003eNaltrexone\u003c\/h1\u003e\n\u003cp\u003eNaltrexone is a prescription medication used to help people recover from opioid or alcohol addiction. It belongs to the drug class \u003cstrong\u003eopioid antagonists\u003c\/strong\u003e, meaning it binds to opioid receptors in the brain but does \u003cstrong\u003enot\u003c\/strong\u003e activate them By occupying these receptors, naltrexone \u003cstrong\u003eblocks the effects of opioid drugs\u003c\/strong\u003e (heroin, prescription painkillers, etc.) – patients feel no euphoria or sedation if they use opioids while on naltrexone. This blockade also extends to opioid-like effects of alcohol, which can help reduce alcohol craving and use. Naltrexone itself has no abuse potential or sedative effect and is not addictive. Importantly, it \u003cstrong\u003edoes not\u003c\/strong\u003e relieve withdrawal symptoms and should only be started once a person is fully detoxified. (Starting naltrexone too soon can trigger acute withdrawal on someone who still has opioids in their system.)\u003c\/p\u003e\n\u003cp\u003eNaltrexone works by \u003cstrong\u003eblocking brain opioid receptors\u003c\/strong\u003e. This competitive antagonism prevents opioids from producing reward or sedation. Unlike opioid drugs, naltrexone does not activate these receptors, so it causes no “high,” no physical dependence, and no withdrawal when discontinued. If a patient takes opioid medication while on naltrexone, the opioid has little to no effect – this property helps break the cycle of addiction. Because naltrexone has very high affinity for the mu-opioid receptor, it must be used after withdrawal: patients typically wait about 7–10 days after their last short-acting opioid (or 10–14 days after a long-acting opioid) before beginning naltrexone.\u003c\/p\u003e\n\u003ch2\u003eUses and Administration\u003c\/h2\u003e\n\u003cp\u003eNaltrexone is FDA-approved to support abstinence in both \u003cstrong\u003eopioid use disorder (OUD)\u003c\/strong\u003e and \u003cstrong\u003ealcohol use disorder (AUD)\u003c\/strong\u003e. It is always used \u003cem\u003ewith counseling and support services\u003c\/em\u003e as part of a comprehensive treatment program. Common clinical uses include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOpioid use disorder:\u003c\/strong\u003e After medically supervised detox from opioids, patients receive naltrexone to prevent relapse. The long-acting injectable form (380 mg intramuscular once monthly) is approved for this purpose. Naltrexone blocks any opioids taken, so it removes the incentive to use. Patients must have gone 1–2 weeks without opioids before starting.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAlcohol use disorder:\u003c\/strong\u003e Naltrexone (usually 50 mg by mouth daily) helps people who have recently stopped drinking to avoid relapse. It reduces the rewarding effects of alcohol and diminishes cravings. Unlike disulfiram or some other medications, naltrexone does not punish drinking with sickness – instead it simply blunts the “high” from alcohol.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWeight management (obesity):\u003c\/strong\u003e In combination with bupropion, naltrexone is approved (as the brand \u003cem\u003eContrave\u003c\/em\u003e) to aid in weight loss for obese patients. This use exploits naltrexone’s effect on reward pathways and appetite. (This is a different indication than addiction treatment.)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eNaltrexone is available in two main formulations. The \u003cstrong\u003eoral tablet\u003c\/strong\u003e (50 mg) is taken daily, typically under the brand names ReVia or Depade. This form is often used for alcohol dependence. The \u003cstrong\u003eextended-release injection\u003c\/strong\u003e (380 mg once every 4 weeks) is given by a healthcare provider (brand name Vivitrol) and is approved for both opioid and alcohol dependence. In all cases, naltrexone is \u003cstrong\u003eonly\u003c\/strong\u003e effective when the patient is already abstinent from the abused substance. It is not useful for detoxification itself or for people who are still actively using alcohol or opioids.\u003c\/p\u003e\n\u003ch2\u003eNaltrexone Side Effects\u003c\/h2\u003e\n\u003cp\u003eNaltrexone is generally well tolerated, but it can cause side effects (often mild to moderate). Common side effects include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGastrointestinal:\u003c\/strong\u003e nausea, vomiting, stomach cramps or gas, loss of appetite.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeurologic:\u003c\/strong\u003e headache, dizziness, sleep disturbances (insomnia or fatigue).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePsychiatric\/Mood:\u003c\/strong\u003e anxiety, nervousness, irritability or mood swings.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBecause of these effects, patients are advised to take it with food or a snack if stomach upset occurs. Rare but serious side effects can include liver damage. Naltrexone, especially in high doses, can cause hepatotoxicity, so clinicians monitor liver enzymes. Anyone with acute hepatitis or severe liver disease should not take naltrexone. Other rare reactions (e.g. severe allergic reactions, confusion or hallucinations) have been reported.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImportant precautions:\u003c\/strong\u003e Patients must \u003cstrong\u003ecompletely stop opioids\u003c\/strong\u003e (and often alcohol) \u003cem\u003ebefore\u003c\/em\u003e starting naltrexone. Using naltrexone in someone who still has opioids in their system precipitates immediate withdrawal. Patients should avoid opioid painkillers, illicit opioids, or sedative drugs while on naltrexone, since these will have no effect and may be unsafe. Similarly, heavy drinking is discouraged when taking naltrexone for alcohol use disorder. Naltrexone is \u003cstrong\u003enot\u003c\/strong\u003e recommended for those under 18 years old or for people with acute addiction or other unstable medical conditions.\u003c\/p\u003e\n\u003cp\u003eFinally, an important clinical note: \u003cstrong\u003enaltrexone reduces opioid tolerance\u003c\/strong\u003e. If a patient stops naltrexone (or misses doses) and then relapses to opioid use, even a previously normal dose of opioid can cause overdose, because their tolerance has dropped during abstinence on naltrexone. Patients are always warned about this risk and advised to be cautious if opioid use is resumed.\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003eNaltrexone is an opioid-receptor blocker used to prevent relapse in opioid or alcohol addiction. It comes as a daily pill or a monthly injection, and works by eliminating the pleasurable effects of opioids\/alcohol, thereby helping people maintain sobriety. It is non-addictive and does not cause withdrawal on its own, but requires careful medical supervision due to its effects on liver function and potentials for precipitated withdrawal.\u003c\/span\u003e\u003c\/p\u003e","products":[{"product_id":"naltrexone-hydrochloride-usp-anhydrous-for-compounding-api","title":"Naltrexone Hydrochloride API Powder Bulk For Custom Compounding (Rx)","description":"\u003ch1\u003eNaltrexone Hydrochloride (API Powder)\u003c\/h1\u003e\n\u003cp\u003eNaltrexone hydrochloride is a \u003cstrong\u003epure opioid receptor antagonist\u003c\/strong\u003e used in addiction treatment. It is a synthetic relative of the opioid drug oxymorphone, but unlike opioids it has \u003cstrong\u003eno agonist (euphoric) activity\u003c\/strong\u003e. In other words, naltrexone binds tightly to opioid receptors (especially the mu receptor) and blocks (“antagonizes”) them, preventing opioids (like heroin, morphine or oxycodone) from producing their effects. By doing so, naltrexone can substantially \u003cstrong\u003eblunt or block the “high” from opioids\u003c\/strong\u003e and reduce alcohol’s rewarding effects. It is not addictive itself and does not produce sedation or intoxication. The pure hydrochloride salt is a white crystalline powder (water-soluble ~100 mg\/mL). In pharmaceutical products, naltrexone HCl is the \u003cstrong\u003eactive ingredient (API)\u003c\/strong\u003e in formulating medications such as 50 mg oral tablets (e.g. ReVia) or extended-release intramuscular injections (e.g. Vivitrol) containing naltrexone.\u003c\/p\u003e\n\u003cp\u003eNaltrexone Hydrochloride API (Active Pharmaceutical Ingredient) Powder refers to the raw, pharmacologically active substance used in the manufacture of the final dosage forms (such as tablets, capsules, or injectable solutions) of the drug Naltrexone.\u003c\/p\u003e\n\u003ch2\u003eUses and Administration\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eAlcohol Dependence:\u003c\/strong\u003e Naltrexone is FDA-approved, in combination with counseling and support, to help maintain abstinence in people with alcohol dependence. By blocking opioid receptors, it diminishes the positive reinforcement and craving triggered by drinking. Tablets (50 mg once daily) or monthly injections (380 mg IM) are used in patients who have stopped drinking to help prevent relapse. Clinical guidelines recommend it as one of the first-line medications for moderate-to-severe alcohol use disorder.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eOpioid Use Disorder (Relapse Prevention):\u003c\/strong\u003e Naltrexone is also used after detoxification from opioids. In detoxified, opioid-free individuals, naltrexone (oral or monthly shot) \u003cstrong\u003eblocks the effects of any opioid that someone might take\u003c\/strong\u003e, thereby helping to prevent relapse to opioid abuse. It is often part of a comprehensive treatment program with therapy. Because it has no opioid agonist action, it cannot substitute for methadone or buprenorphine in withdrawal; rather, it is given only \u003cem\u003eafter\u003c\/em\u003e withdrawal to maintain the opioid-free state. (Extended-release naltrexone injections have FDA approval for opioid dependence in patients who have already completed detox.)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eOther and Off-Label Uses:\u003c\/strong\u003e In combination with bupropion, naltrexone (as Contrave) is used for weight management in obesity (it modulates reward pathways to reduce appetite). It has also been used off-label for impulse-control disorders or chronic pain syndromes, but these are less common and not FDA-approved. Notably, naltrexone is being studied in \u003cstrong\u003ehereditary angioedema\u003c\/strong\u003e to reduce swelling attacks, and low-dose naltrexone (LDN) is used experimentally in conditions like fibromyalgia or multiple sclerosis, though these uses are investigational.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eDosage Forms:\u003c\/strong\u003e As an API, naltrexone HCl powder is formulated into tablets (50 mg) or dissolved to make the long-acting injectable suspension (380 mg). For oral use, the common dose is 50 mg once daily. The extended-release injection (Vivitrol) is 380 mg given \u003cstrong\u003eintramuscularly once a month\u003c\/strong\u003e by a healthcare provider. Because naltrexone has high first-pass metabolism, oral bioavailability is low (5–40%), so higher doses or depot formulations are used to achieve effect.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eImportant:\u003c\/strong\u003e A patient must be \u003cstrong\u003eopioid-free (detoxified)\u003c\/strong\u003e before taking naltrexone. Giving naltrexone to someone with opioids in their system will precipitate acute withdrawal (sweating, vomiting, restlessness, etc.). In practice, doctors often perform a naloxone challenge or wait 7–10 days after last opioid use to ensure safety. Likewise, patients should avoid any opioid pain medication while on naltrexone (and for some days after stopping) because opioid analgesics will have little or no effect, and trying to override the blockade can be dangerous.\u003c\/p\u003e\n\u003ch2\u003eSide Effects and Adverse Reactions\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eCommon Side Effects:\u003c\/strong\u003e The most frequent side effects are mild and typically GI or neuro-psychiatric. These include \u003cstrong\u003enausea, headache, dizziness, insomnia, fatigue, anxiety, vomiting, and abdominal pain\u003c\/strong\u003e. In studies, nausea affected about 10% of patients and headache about 7%. Some people report nervousness, insomnia or sleepiness. These symptoms often occur when starting treatment and may lessen over time or with continued therapy.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eInjection-Related Reactions:\u003c\/strong\u003e For the extended-release injectable form, \u003cstrong\u003einjection-site reactions\u003c\/strong\u003e are common (pain, redness, swelling, nodule formation) and usually mild or moderate. Rarely, severe necrotic skin reactions have occurred, requiring medical care. Only a trained provider should give Vivitrol injections to minimize these risks.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eSerious Adverse Effects:\u003c\/strong\u003e Although naltrexone itself is not habit-forming, it has a warning for \u003cstrong\u003eliver toxicity\u003c\/strong\u003e at high doses. High doses (well above standard therapy) have caused liver enzyme elevations and hepatitis in some patients. Even at normal doses, patients with pre-existing liver disease should be monitored closely (see \u003cem\u003ePrecautions\u003c\/em\u003e). Chronic alcoholics often already have liver impairment, so baseline and periodic liver tests are advised. Patients should report any signs of hepatitis (fatigue, jaundice, dark urine) promptly.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003ePrecipitated Withdrawal:\u003c\/strong\u003e As mentioned, inadvertent administration to an opioid-dependent person causes \u003cstrong\u003eacute withdrawal syndrome\u003c\/strong\u003e. Symptoms can be very uncomfortable or even dangerous. Therefore, one must confirm the patient is opioid-free before starting naltrexone.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eOverdose Risk Post-Treatment:\u003c\/strong\u003e An important consideration is \u003cstrong\u003edecreased opioid tolerance\u003c\/strong\u003e. After stopping naltrexone, tolerance to opioids is low. If a patient relapses and takes opioids (especially at doses previously tolerated), there is a high risk of overdose (respiratory failure). Patients and families must be warned that \u003cstrong\u003epost-naltrexone, even a small amount of opioid can be fatal\u003c\/strong\u003e because the body is unprepared.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003ePsychiatric Effects:\u003c\/strong\u003e Some patients on naltrexone report mood changes, including \u003cstrong\u003edepression or anxiety\u003c\/strong\u003e. In studies of alcoholics, depression and suicidal ideation occurred in a small percentage, but it is unclear if naltrexone caused this. Any new or worsening depression should be taken seriously, and patients should be monitored for suicidal thoughts.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003ePrecautions and Counseling\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eOpioids:\u003c\/strong\u003e Do \u003cem\u003enot\u003c\/em\u003e take naltrexone if you are currently on opioid painkillers or methadone\/buprenorphine. Doing so can precipitate severe withdrawal. Naltrexone should only be started when a patient is fully detoxified.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eLiver Disease:\u003c\/strong\u003e Use with caution in \u003cstrong\u003eliver impairment\u003c\/strong\u003e. High doses of naltrexone have caused liver injury, and patients with acute hepatitis or severe cirrhosis were excluded from trials. Monitor liver enzymes before and during treatment; discontinue if enzymes rise substantially (e.g. \u0026gt; 3× normal) or if hepatitis symptoms appear.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003ePregnancy and Breastfeeding:\u003c\/strong\u003e There are no adequate studies in pregnant women. Animal data showed fetal loss at very high doses, so naltrexone is FDA pregnancy category C – it should only be used if clearly needed. It is unknown if naltrexone passes into human breast milk, but caution is advised as it did in rats. A decision should balance the risk of untreated addiction vs. potential drug exposure to fetus\/infant.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003ePediatric Use:\u003c\/strong\u003e Safety in children under 18 has not been established. Naltrexone is generally prescribed for adults.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eInteractions:\u003c\/strong\u003e The major “interaction” is with \u003cstrong\u003eopioids\u003c\/strong\u003e: naltrexone will block opioid analgesic effects. A patient on naltrexone should not expect relief from opioids; alternative (non-opioid) pain treatments are needed if analgesia is required. There are no major drug metabolism interactions (naltrexone is not processed by cytochrome P450 enzymes to a significant extent). However, combining naltrexone with bupropion (as in Contrave) or other psychotropic drugs does require medical guidance. Also, because naltrexone can slightly increase endogenous endorphins breakdown, some hormone levels (like cortisol) might change, but the clinical significance is unclear.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003ePatient Counseling:\u003c\/strong\u003e Key points for patients include: inform your doctor of all medications (especially painkillers or antidepressants), do not stop therapy abruptly without medical advice, and always tell future doctors you are on naltrexone (so they know opioids won’t work). Carrying a medical alert card or informing family members that naltrexone is in your system is wise, particularly because of the opioid overdose risk post-treatment.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSide Effects (Summary)\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cem\u003eCommon:\u003c\/em\u003e Nausea, vomiting, diarrhea, abdominal cramps, headache, dizziness, drowsiness, insomnia, anxiety, fatigue.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eInjection-specific:\u003c\/em\u003e Injection site pain, swelling, itching, abscess or necrosis (rare but serious).\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eSerious but uncommon:\u003c\/em\u003e Elevated liver enzymes\/hepatitis, opioid-withdrawal symptoms if misused, severe allergic reaction (very rare). Psychiatric: depression or suicidal thoughts (monitor mood).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003ePatients should seek immediate help if they experience severe abdominal pain, jaundice, mental\/mood changes, or signs of an opioid overdose (slow breathing, severe drowsiness) after stopping naltrexone.\u003c\/p\u003e\n\u003ch2\u003eStorage and Handling\u003c\/h2\u003e\n\u003cp\u003eNaltrexone hydrochloride API powder is used in manufacturing; finished dosage forms should be handled by professionals. Tablets should be stored at room temperature away from moisture. The injectable suspension (Vivitrol) must be refrigerated and used before its expiration. Opened kits or vials should not be reused. Keep all medications out of reach of children.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eUses of Naltrexone Hydrochloride API\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRaw material\u003c\/strong\u003e: Used by pharmaceutical manufacturers to make various naltrexone hydrochloride medications (e.g., tablets, extended-release injections).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompounding\u003c\/strong\u003e: Sometimes compounded by specialized pharmacies for custom-made dosage forms.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhat is Naltrexone?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eNaltrexone\u003c\/strong\u003e is a medication classified as an \u003cstrong\u003eopioid antagonist\u003c\/strong\u003e. Its primary medical uses are:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eTreatment of alcohol dependence\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003ePrevention of relapse in opioid dependence\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhat is \"API\" in Pharmaceuticals?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAPI (Active Pharmaceutical Ingredient)\u003c\/strong\u003e is the term for the substance (or substances) in a pharmaceutical drug that is biologically active. The \u003cstrong\u003eAPI powder\u003c\/strong\u003e is the pure drug substance, before it is formulated into a final drug product.\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eFeatures \u0026amp; Benefits\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eUltra-Pure, Pharmaceutical Grade Naltrexone:\u003c\/strong\u003e Meets strict USP standards for identity, purity, potency, and consistency—ideal for safe, effective compounding and reliable patient outcomes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVersatile Compounding Applications:\u003c\/strong\u003e Perfect for the preparation of oral capsules, sublingual troches, suspensions, and topical creams — tailored to each patient’s needs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAlcohol \u0026amp; Opioid Addiction Recovery:\u003c\/strong\u003e Clinically proven and FDA-approved mainstay for medical management of \u003cstrong\u003ealcohol use disorder\u003c\/strong\u003e and \u003cstrong\u003eopioid dependence\u003c\/strong\u003e, helping prevent relapse and support abstinence.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLow Dose Naltrexone (LDN) Therapy:\u003c\/strong\u003e Widely used in integrative medicine for \u003cstrong\u003eautoimmune conditions\u003c\/strong\u003e, chronic pain (fibromyalgia, MS), inflammation, thyroid disorders (Hashimoto’s), and off-label wellness protocols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWeight Loss \u0026amp; Metabolic Health:\u003c\/strong\u003e Increasingly compounded in specialty weight loss (anti-obesity) regimens, often paired with bupropion or other agents for enhanced results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTrusted Quality:\u003c\/strong\u003e Industry leader in compounding ingredients—batch-tested, cGMP-manufactured, and compliant with all regulatory requirements for pharmacies and clinicians worldwide.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\u003cstrong\u003eTop Clinical \u0026amp; Integrative Applications\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eAlcohol use disorder\/management\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eOpioid use disorder\/recovery support\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eLow-dose naltrexone (LDN) for autoimmune diseases\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eCompounded formulas for multiple sclerosis, chronic fatigue, fibromyalgia\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eWeight management (anti-obesity compounding)\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eChronic pain and inflammation treatment\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eCustom capsules, sublingual tablets, oral suspensions, topical preparations\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003ePersonalized medicine protocols\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\u003cstrong\u003eWhy Choose Naltrexone Hydrochloride API Powder?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eHighest purity and batch-to-batch consistency\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eProvides pharmacists and clinicians with precision dosing flexibility\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eSupports multiple indications with proven safety and efficacy\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eTrusted by top compounding pharmacies, integrative physicians, and addiction specialists\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eBacked stringent quality assurance and industry leadership\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\u003cstrong\u003eTop Searched Terms\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003enaltrexone hydrochloride powder for compounding\u003c\/li\u003e\n\u003cli\u003eAPI naltrexone compounding pharmacy\u003c\/li\u003e\n\u003cli\u003elow-dose naltrexone (LDN) benefits and uses\u003c\/li\u003e\n\u003cli\u003enaltrexone for alcohol dependence recovery\u003c\/li\u003e\n\u003cli\u003eopioid addiction medication compounding\u003c\/li\u003e\n\u003cli\u003enaltrexone HCl pure powder for capsules\u003c\/li\u003e\n\u003cli\u003ebest pharmacy ingredient for LDN capsules\/troches\u003c\/li\u003e\n\u003cli\u003ecompounded naltrexone for chronic pain, autoimmune disease\u003c\/li\u003e\n\u003cli\u003eabuse deterrent opioid therapy\u003c\/li\u003e\n\u003cli\u003enaltrexone for weight loss and obesity\u003c\/li\u003e\n\u003cli\u003eMedisca naltrexone powder supplier\u003c\/li\u003e\n\u003cli\u003ecustom addiction recovery formulations\u003c\/li\u003e\n\u003cli\u003ehigh-purity naltrexone for pharmacy compounding\u003c\/li\u003e\n\u003cli\u003eintegrative health and LDN therapy API\u003c\/li\u003e\n\u003cli\u003ecompounding pharmacy naltrexone HCl\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\u003cstrong\u003eSafety \u0026amp; Side Effects (Patient Counseling Points)\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003ePossible Side Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNausea, headache, dizziness, fatigue\u003c\/li\u003e\n\u003cli\u003eInsomnia or vivid dreams\u003c\/li\u003e\n\u003cli\u003eAbdominal discomfort\u003c\/li\u003e\n\u003cli\u003eRare: Hepatic enzyme elevation—monitor as clinically indicated\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003ePrecautions:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAppropriate for use by prescription only and under medical supervision\u003c\/li\u003e\n\u003cli\u003eNot for use in patients currently dependent on opioids (risk of precipitated withdrawal)\u003c\/li\u003e\n\u003cli\u003eUse caution in patients with liver disease—monitor liver function regularly\u003c\/li\u003e\n\u003cli\u003eNot intended for direct consumer or home compounding; professional use only\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eChemical Formula:\u003c\/strong\u003e C20H23NO4•HCl\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHazardous Drug (NIOSH\u003c\/strong\u003e: No\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTemperature Requirement\u003c\/strong\u003e\u003cbr\u003eControlled Room Temp 15-25°C\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHygroscopic:\u003c\/strong\u003e Yes\u003cbr\u003e\u003cstrong\u003eLight-sensitive\u003c\/strong\u003e: Yes\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003cstrong\u003eEmpower your pharmacy and clinic with Naltrexone Hydrochloride API Powder for Compounding—the clinical gold standard for custom alcohol \u0026amp; opioid recovery, innovative LDN therapy, and all your patient-centered wellness protocols.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"Mountainside Medical","offers":[{"title":"1 g","offer_id":40078836170824,"sku":"3296-06","price":99.0,"currency_code":"USD","in_stock":true},{"title":"5 g","offer_id":40078836203592,"sku":"3296-03","price":425.0,"currency_code":"USD","in_stock":true},{"title":"25 g","offer_id":40078836236360,"sku":"3296-04","price":1450.0,"currency_code":"USD","in_stock":true},{"title":"100 g","offer_id":40078836269128,"sku":"3296-05","price":3800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Naltrexone_Hydrochloride_API_Powder_Active_Pharmaceutical_Ingredient.jpg?v=1759512176"},{"product_id":"naltrexone-hydrochloride-usp-dihydrate-for-compounding-api","title":"Naltrexone Hydrochloride USP (Dihydrate) For Compounding (API)","description":"\u003cp\u003eNaltrexone Hydrochloride USP (Dihydrate) is an active pharmaceutical ingredient (API) that is commonly used in the treatment of alcohol and opioid dependence. It works by blocking the effects of opioids and reducing the cravings for alcohol. Naltrexone Hydrochloride USP (Dihydrate) is a synthetic compound that belongs to the class of drugs known as opioid antagonists. It is chemically similar to oxymorphone and naloxone. This drug is typically used in conjunction with counseling and support to help individuals with addiction maintain sobriety. It is available in both oral and injectable forms. \u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cstrong\u003eShips in 2-4 business days.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eNaltrexone Hydrochloride USP is a pharmaceutical ingredient used in compounding to treat alcohol and opioid dependence. It acts by blocking the effects of alcohol and opioids within the brain, reducing the cravings for these substances and helping individuals stay sober. During compounding, Naltrexone Hydrochloride may be combined with other medications or used in a customized dosage form to suit the patient’s individual needs. It is also available in tablet form for standard use.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePhysical State:\u003c\/strong\u003e Solid\u003cbr\u003e\u003cstrong\u003eDescription:\u003c\/strong\u003e White to almost white powder\u003cbr\u003e\u003cstrong\u003eOdor:\u003c\/strong\u003e Almost odorless\u003cbr\u003e\u003cstrong\u003eFlammability:\u003c\/strong\u003e May be combustible at high temperature\u003cbr\u003e\u003cstrong\u003eSolubility:\u003c\/strong\u003e Very soluble in water; slightly soluble in alcohol; practically insoluble in dichloromethane and methylene chloride\u003cbr\u003e\u003cstrong\u003epH:\u003c\/strong\u003e 4.5 - 6.0 (1%)\u003cbr\u003e\u003cstrong\u003eConditions to avoid:\u003c\/strong\u003e Moisture, sunlight and extreme temperatures. Hygroscopic - Avoid exposure to moisture\u003cbr\u003e\u003cstrong\u003eChemical Stability:\u003c\/strong\u003e Stable under recommended storage conditions. Store in original container, tightly sealed, protected from direct sunlight and moisture\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCAS Number: 850808-02-5\u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProperty: Light Sensitive - Hygroscopic\u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e","brand":"Mountainside Medical","offers":[{"title":"1 g","offer_id":40078837645384,"sku":"0887-06","price":79.0,"currency_code":"USD","in_stock":true},{"title":"5 g","offer_id":40078837678152,"sku":"0887-03","price":369.0,"currency_code":"USD","in_stock":true},{"title":"25 g","offer_id":40078837710920,"sku":"0887-04","price":1200.0,"currency_code":"USD","in_stock":true},{"title":"100 g","offer_id":40078837743688,"sku":"0887-05","price":3800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Naltrexone-Hydrochloride-USP-_Dihydrate_-For-Compounding.jpg?v=1707244633"},{"product_id":"naltrexone-hydrochloride-usp-50-mg-tablets-blister-pack-10-each-x-3-30-count-rx","title":"Naltrexone Hydrochloride 50 mg Tablets Blister Pack 10 each x 3 (30 Count) (RX)","description":"\u003cp\u003eNaltrexone Hydrochloride USP 50 mg Tablets Blister Pack is a prescription medication used to help treat opioid or alcohol dependence. Each blister pack contains 10 tablets of 50 mg strength, for a total of 30 tablets per pack. Naltrexone hydrochloride works by blocking the effects of opioids in the brain and reducing the desire to use them. This medication should be used as part of a comprehensive treatment program that includes counseling and behavioral therapy. It is important to follow the dosage instructions and precautions provided by a healthcare professional when taking this medication.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow to use  Naltrexone Hydrochloride USP 50 mg Tablets:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Check the label: Before using Naltrexone Hydrochloride USP 50 mg Tablets, carefully check the packaging and label to ensure that it is properly sealed and has not expired. Make sure to read and follow all the instructions and warnings provided.\u003cbr\u003e2. Consult a doctor: Naltrexone is a prescription medication and should only be used under the supervision of a doctor. Before starting treatment, consult your doctor to determine if this medication is right for you and to determine the appropriate dosage.\u003cbr\u003e3. Take as directed: Naltrexone Hydrochloride USP 50 mg Tablets can be taken with or without food, but should be taken at the same time every day. Follow the dosage instructions provided by your doctor and do not exceed the recommended dose.\u003cbr\u003e4. Swallow the tablet whole: Do not chew, crush, or break the tablet as this can affect the way the medication is released in your body. Swallow the tablet whole with a full glass of water.\u003cbr\u003e5. Keep track of your doses: It is important to take your medication as prescribed and to keep track of the doses you have taken. If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.\u003cbr\u003e6. Avoid alcohol and opioid drugs: Naltrexone blocks the effects of opioid medications and can cause serious side effects if taken with opioid drugs or alcohol. Avoid consuming any products containing alcohol or taking any opioid medications while using Naltrexone.\u003cbr\u003e7. Be aware of potential side effects: Naltrexone may cause side effects such as nausea, headache, dizziness, or fatigue. If you experience any severe or persistent side effects, contact your doctor immediately.\u003cbr\u003e8. Complete the full course of treatment: Naltrexone is usually prescribed for a minimum of 3 months for it to be effective. It is important to complete the full course of treatment even if you start feeling better.\u003cbr\u003e9. Store properly: Keep the tablets in their blister pack until it is time to take them. Store them at room temperature, away from heat and moisture, and out of reach of children.\u003cbr\u003e10. Dispose of unused medication properly: If you have any remaining medication after you have completed your treatment, dispose of it properly according to your local regulations or return it to your pharmacy. Do not flush it down the toilet or pour it down the drain.\u003c\/p\u003e","brand":"Major Pharmaceuticals","offers":[{"title":"Default Title","offer_id":40089867616328,"sku":"00904-7036-04","price":99.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Naltrexone-Hydrochloride-USP-50-mg-Tablets-Blister-Pack.jpg?v=1707054754"},{"product_id":"contrave-naltrexone-hydrochloride-usp-8-mg-90mg-extended-release-tablets-120-count-rx","title":"Contrave Naltrexone 8 mg + Bupropion 90 mg Extended Release Tablets, 120\/Bottle (RX)","description":"\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003cstrong\u003eContrave\u003c\/strong\u003e is a prescription combination medication for chronic weight management. Each extended‐release Contrave tablet contains 8 mg of naltrexone HCl (an opioid antagonist) and 90 mg of bupropion HCl (an antidepressant). It was approved by the FDA in September 2014 as an adjunct to diet and exercise for weight loss. Contrave is intended for adults with a body mass index (BMI) ≥30 (obese) or ≥27 (overweight) \u003cem\u003eplus\u003c\/em\u003e at least one weight-related condition (such as hypertension, type 2 diabetes, or dyslipidemia). It is \u003cstrong\u003enot\u003c\/strong\u003e FDA-approved for use in children or adolescents; clinical studies have only been done in adults. In practice, Contrave is always prescribed along with medical supervision and lifestyle changes (diet and exercise) to maximize benefit\u003c\/span\u003e.\u003c\/p\u003e\n\u003ch2\u003eMechanism of Action\u003c\/h2\u003e\n\u003cp\u003eThe exact way Contrave causes weight loss is not fully understood. In general, bupropion and naltrexone act on brain pathways that regulate hunger and reward. Bupropion (a dopamine\/norepinephrine reuptake inhibitor) stimulates pro-opiomelanocortin (POMC) neurons in the hypothalamus to release appetite-suppressing peptides (α-MSH) and beta-endorphin. Normally, beta-endorphin would then feed back via opioid receptors to limit POMC activity. Naltrexone (an opioid receptor blocker) \u003cstrong\u003eprevents\u003c\/strong\u003e this feedback inhibition. Together, the drugs synergistically raise the activity of POMC cells, leading to increased satiety signals, reduced food intake, and (in animal studies) higher energy expenditure. They also affect reward circuits (the mesolimbic dopamine pathway) to diminish cravings and the pleasurable response to high-fat\/sugar foods. In short, Contrave helps “turn down” hunger signals and cravings by acting on both the brain’s appetite center and its reward center.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details and Features:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eActive Ingredients:\u003c\/strong\u003e Each tablet contains 8 mg of Naltrexone Hydrochloride and 90 mg of Bupropion Hydrochloride, a unique combination designed to target areas of the brain associated with hunger and cravings.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExtended Release Formulation\u003c\/strong\u003e: The extended-release tablets are crafted to provide a steady delivery of active ingredients throughout the day, ensuring effective appetite control and sustained weight management support.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuantity:\u003c\/strong\u003e Offered in a convenient 120-count bottle, providing a comprehensive supply to support your weight management journey.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription-Based: \u003c\/strong\u003eIntended for use in conjunction with a doctor-approved exercise, behavior change, and reduced-calorie diet program in adults with a significant body mass index (BMI).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eIndications and Dosage\u003c\/h2\u003e\n\u003cp\u003eContrave is indicated \u003cstrong\u003eonly\u003c\/strong\u003e as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in appropriately selected adults. Typical candidates are those with a BMI ≥30, or BMI ≥27 with comorbidities (e.g. type 2 diabetes). It is \u003cstrong\u003enot\u003c\/strong\u003e meant for short-term or cosmetic use.\u003c\/p\u003e\n\u003cp\u003eThe standard dosing regimen is a gradual 4-week titration up to a maintenance dose of 32 mg naltrexone\/360 mg bupropion per day. For example (extended-release tab of 8\/90 mg each):\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eWeek 1:\u003c\/strong\u003e 1 tablet each morning (8 mg\/90 mg total per day).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWeek 2:\u003c\/strong\u003e 1 tablet morning + 1 tablet evening (16 mg\/180 mg per day).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWeek 3:\u003c\/strong\u003e 2 tablets morning + 1 evening (24 mg\/270 mg per day).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWeek 4 and on:\u003c\/strong\u003e 2 tablets twice daily (32 mg\/360 mg per day).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIf this full dose is tolerated, it is continued. However, by 12 weeks of treatment at the full dose, patients should have lost at least ~5% of their starting weight. If \u003cstrong\u003e5% weight loss\u003c\/strong\u003e is not achieved by that time, Contrave is usually discontinued, since further benefit is unlikely. These criteria (and dosing schedule) come from the FDA-approved label recommendations. Elderly patients (\u0026gt;65) may be more sensitive to side effects, and Contrave has not been studied in children. The extended-release tablets should be swallowed whole and \u003cstrong\u003enever\u003c\/strong\u003e chewed or crushed.\u003c\/p\u003e\n\u003ch2\u003eClinical Efficacy\u003c\/h2\u003e\n\u003cp\u003eIn clinical trials, Contrave (used with diet\/exercise) produced modest but significant weight loss compared to placebo. In a 56-week pivotal study (COR-I), the mean weight change was –5.4% on Contrave versus –1.3% on placebo. About \u003cstrong\u003e42%\u003c\/strong\u003e of Contrave-treated patients achieved ≥5% weight loss, vs ~17% of placebo patients. Similar benefits were seen in other trials and in diabetic patients. Differences faded if treatment was stopped. In real terms, a 5–10% weight reduction (this range is typical for Contrave or other similar drugs) has been associated with meaningful health improvements – for example, better blood sugar control, reduced sleep apnea symptoms, improved mobility, etc.. Therefore, Contrave can be a useful adjunct when lifestyle changes alone are insufficient, but it should not be viewed as a quick fix.\u003c\/p\u003e\n\u003ch2\u003eSide Effects and Safety\u003c\/h2\u003e\n\u003cp\u003eThe most common \u003cstrong\u003eside effects\u003c\/strong\u003e (reported in at least 5–10% of patients) are mostly related to the gastrointestinal and nervous system. In placebo-controlled trials, patients on Contrave versus placebo reported:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNausea:\u003c\/strong\u003e ~32.5% (vs 6.7% on placebo).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConstipation:\u003c\/strong\u003e ~19.2% (vs 7.2%).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHeadache:\u003c\/strong\u003e ~17.6% (vs 10.4%).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVomiting:\u003c\/strong\u003e ~10.7% (vs 2.9%).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDizziness:\u003c\/strong\u003e ~9.9% (vs 3.4%).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInsomnia:\u003c\/strong\u003e ~9.2% (vs 5.9%).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDry mouth, diarrhea, other:\u003c\/strong\u003e also noted, though less common.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eMost side effects are mild to moderate and tend to occur during the initial titration. Many patients find that nausea and headaches lessen after a few weeks. If side effects become intolerable, dose adjustments or discontinuation may be needed.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSerious Warnings:\u003c\/strong\u003e Contrave carries an FDA boxed warning (the strictest safety warning) because it contains bupropion, an antidepressant known to increase the risk of suicidal thoughts and neuropsychiatric events in some people (especially those under 24 or with psychiatric history). Although Contrave itself was not found to increase suicidality in trials, physicians and patients are advised to monitor mood, depression, or suicidal ideation during use. Any unusual mood or behavior changes should prompt immediate medical attention.\u003c\/p\u003e\n\u003cp\u003eCardiovascular effects are a concern: Contrave can raise resting heart rate and blood pressure slightly. In trials the average rise was small (∼1 mmHg), but because of this, Contrave is used \u003cstrong\u003ecautiously\u003c\/strong\u003e in patients with existing heart disease or high blood pressure. Heart rate and BP should be monitored periodically. If severe hypertension develops, Contrave should be stopped and blood pressure treated. Notably, unlike some older anti-obesity drugs, Contrave has \u003cstrong\u003enot\u003c\/strong\u003e been linked to significant heart valve issues or severe cardiac events in trials (though long-term cardiovascular outcome studies had been required post-approval).\u003c\/p\u003e\n\u003cp\u003eContraindications and other precautions include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSeizure risk:\u003c\/strong\u003e Bupropion lowers the seizure threshold in a dose-related manner. Patients with seizure disorders, active alcohol or benzodiazepine withdrawal, eating disorders (anorexia\/bulimia) or any condition that predisposes to seizures should \u003cstrong\u003enot\u003c\/strong\u003e take Contrave. Avoid abrupt discontinuation of seizure medications or sedatives while on Contrave.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOpioid antagonism:\u003c\/strong\u003e Because naltrexone blocks opioid receptors, Contrave \u003cstrong\u003eprevents\u003c\/strong\u003e opioid pain medications from working and can precipitate withdrawal. It is contraindicated in patients on chronic opioid therapy, and must be stopped before any opioid use. Patients requiring on-demand opioids (e.g. for pain) should not use Contrave; if opioids are needed, Contrave is discontinued and opioid doses adjusted.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMAOI interaction:\u003c\/strong\u003e Contrave must not be used with monoamine oxidase inhibitors (MAOIs) or within 14 days of MAOI therapy, due to risk of hypertensive crisis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOther drugs:\u003c\/strong\u003e Use caution with any other bupropion-containing product (eg, for smoking cessation) – do not co-administer.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCommon drug interactions include CYP2B6 inhibitors (e.g. clopidogrel), which may raise bupropion levels; dose adjustment is recommended as per label. Because Contrave is an extended-release formulation, co-administered medications or conditions that alter gastrointestinal function could affect its absorption.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePregnancy\/Breastfeeding:\u003c\/strong\u003e Weight-loss drugs are generally avoided in pregnancy. The Contrave label warns that weight loss during pregnancy may harm the fetus, and recommends discontinuing if pregnancy occurs. Bupropion alone has been studied in pregnancy (no large signals of birth defects), but combined with naltrexone it is still not recommended. Breastfeeding mothers should also avoid Contrave due to unknown risk. Women of childbearing potential should use contraception and discuss pregnancy plans with their doctor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSpecial Populations:\u003c\/strong\u003e Contrave is \u003cstrong\u003enot approved\u003c\/strong\u003e for anyone under 18. It has not been extensively studied in the very elderly or those with severe liver\/kidney impairment. In patients over 65, lower doses or extra caution may be considered due to CNS side effects (e.g. dizziness, insomnia). Use in renal or hepatic impairment follows the prescribing guidelines: mild impairment requires no change, but moderate\/severe renal disease should not exceed 1 tablet twice daily.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAbuse potential:\u003c\/strong\u003e Unlike stimulant weight-loss drugs, Contrave does \u003cstrong\u003enot\u003c\/strong\u003e appear to have abuse potential. It is not a controlled substance (no “schedule” restriction). It may even be helpful in patients who smoke or have depression\/ADHD because of bupropion’s dual action (though again, it is not indicated as a smoking-cessation or antidepressant drug).\u003c\/p\u003e\n\u003ch1\u003eContrave vs Phentermine\u003c\/h1\u003e\n\u003cp\u003eBoth \u003cstrong\u003eContrave (naltrexone\/bupropion)\u003c\/strong\u003e and \u003cstrong\u003ephentermine\u003c\/strong\u003e are prescription weight-loss medications, but they differ greatly in drug class, how they work, recommended use, and side effects. Contrave is a fixed-dose combo of naltrexone (an opioid antagonist) and bupropion (an antidepressant) \u003cstrong\u003eapproved for long-term weight management\u003c\/strong\u003e. It’s indicated as an adjunct to diet and exercise in adults with obesity (BMI ≥30) or overweight (BMI ≥27) plus a weight-related condition. In contrast, phentermine is a \u003cstrong\u003esympathomimetic stimulant\u003c\/strong\u003e (amphetamine-like) approved only for \u003cstrong\u003eshort-term\u003c\/strong\u003e use (typically a few weeks, up to 12) as an appetite suppressant in similar adult patients (BMI ≥30, or ≥27 with risk factors). In other words, Contrave is used chronically (with gradual dose titration) to help maintain weight loss, whereas phentermine is used acutely to jump-start weight loss.\u003c\/p\u003e\n\u003ch2\u003eSummary\u003c\/h2\u003e\n\u003cp\u003eIn summary, Contrave is a combination naltrexone\/bupropion medication approved for obesity management in adults with appropriate BMI criteria. It works by reducing hunger and cravings through complementary brain pathways. Clinical trials show a \u003cem\u003emoderate\u003c\/em\u003e weight loss benefit (on average a few percent above placebo), so it must be used in conjunction with diet, exercise, and behavior changes for best effect. The drug has known side effects (especially nausea and neuropsychiatric vigilance) and important warnings (suicidality, seizures, opioid interactions). Patients should be carefully selected and monitored, and the therapy stopped if weight loss is inadequate over 12 weeks.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNote:\u003c\/strong\u003e This overview is for informational purposes only. Treatment decisions should always be made in consultation with a qualified healthcare professional, who can assess individual risks and benefits before prescribing any weight-loss medication.\u003c\/p\u003e","brand":"Curram Pharmaceuticals","offers":[{"title":"Default Title","offer_id":40089867878472,"sku":"51267-0890-99","price":865.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Contrave-Naltrexone-Hydrochloride-USP-8-mg.jpg?v=1733427464"},{"product_id":"vivitrol-naltrexone-extended-release-injectable-suspension-380mg-rx","title":"Naltrexone Extended-Release injectable Suspension 380 mg Vivitrol (RX)","description":"\u003cp\u003eVivitrol Naltrexone Extended-Release Injectable Suspension 380mg is a medication used to help prevent relapse in those who have recently stopped using opioids or alcohol. It is a once-monthly injection that contains naltrexone, which works by blocking the effects of opioids and alcohol in the brain. This can help reduce cravings and prevent a relapse from occurring. Vivitrol is intended to be used in combination with counseling or other support programs as part of a comprehensive treatment plan for substance use disorders.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does it work?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVivitrol is a naltrexone extended-release injectable suspension, a medication used to treat alcohol and opioid dependence. It works by blocking the effects of endorphins, the body's natural \"feel-good\" chemicals, in the brain. This helps reduce the rewarding effects of alcohol and opioids, leading to decreased cravings and reduced desire to use these substances.\u003cbr\u003e\u003cbr\u003eNaltrexone binds to and blocks the receptors in the brain that are normally activated by endorphins. By blocking these receptors, naltrexone prevents the rewarding effects of alcohol and opioids, making these substances less appealing to use. It also helps decrease the amount of dopamine released in response to alcohol and opioids, which can also reduce the reinforcing effects of these substances.\u003cbr\u003e\u003cbr\u003eVivitrol is an extended-release formulation, meaning it is slowly released into the body over a period of time. This allows for consistent levels of naltrexone in the body and reduces the frequency of injections needed.\u003cbr\u003e\u003cbr\u003eVivitrol is often used as part of a comprehensive treatment program that includes counseling and support. It is not a cure for alcohol or opioid dependence, but it can help individuals maintain abstinence and reduce the risk of relapse.\u003c\/p\u003e","brand":"Alkermes","offers":[{"title":"Default Title","offer_id":40089870336072,"sku":"65757-0300-01","price":2275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Vivitrol-Naltrexone-Extended-Release-injectable-Suspension-380mg.jpg?v=1707056651"},{"product_id":"naltrexone-hydrochloride-tablets-50-mg-unit-dose-3-x10s-30-count-rx","title":"Naltrexone Hydrochloride Tablets 50 mg Unit Dose (3 x10's) 30 Count (RX)","description":"\u003cp\u003eThe Naltrexone Hydrochloride Tablets are formulated to provide dopamine system stabilization by acting as an opioid receptor antagonist. 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As an opioid antagonist, Naltrexone blocks the effects of opioids, reducing cravings and the rewarding effects of alcohol and narcotics. It is most effective when used as part of a comprehensive treatment plan that includes counseling and support. By helping to prevent relapse, Naltrexone can assist individuals in maintaining abstinence and achieving long-term recovery from substance dependence.\u003c\/p\u003e\n\u003cp\u003eEmpower yourself with Naltrexone Hydrochloride 50 mg Film-Coated Tablets by Accord Healthcare, a proven therapeutic solution designed to support individuals in their journey toward recovery from opioid dependence and alcohol use disorders. This medication assists in reducing cravings and diminishing the rewarding effects of these substances, promoting a healthier, more balanced lifestyle. With a commitment to quality and efficacy, Accord Healthcare provides a reliable, once-daily treatment option for ongoing support.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details and Features:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eActive Ingredient:\u003c\/strong\u003e Each tablet contains 50 mg of Naltrexone Hydrochloride, a well-researched opioid antagonist.\u003cbr\u003e\u003cstrong\u003eFilm-Coated Tablets:\u003c\/strong\u003e Coated for ease of swallowing and reduced gastrointestinal irritation.\u003cbr\u003e\u003cstrong\u003eQuantity: \u003c\/strong\u003eSupplied in a 30-count bottle, providing a full month's support per prescription.\u003cbr\u003e\u003cstrong\u003eTrusted Brand:\u003c\/strong\u003e Developed by Accord Healthcare, a leader in manufacturing high-quality generic pharmaceuticals.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanism of Action:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNaltrexone works by competitively binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids. This action helps reduce cravings and discourage opioid misuse. For alcohol use disorder, the exact mechanism is not fully understood but is believed to involve similar blockade of reward pathways, thereby reducing cravings and the pleasurable effects associated with alcohol consumption.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for Use:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e1. Dosage: \u003c\/strong\u003eTake one 50 mg tablet orally once daily, as directed by your healthcare provider.\u003cbr\u003e\u003cstrong\u003e2. Administration:\u003c\/strong\u003e Can be taken with or without food. Swallow the tablet whole; do not crush or chew.\u003cbr\u003e\u003cstrong\u003e3. Consistency: \u003c\/strong\u003eFor optimal results, adhere to the prescribed dosing schedule and maintain regular follow-up with your healthcare provider.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWarnings:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eContraindications:\u003c\/strong\u003e Do not take if currently using opioids or if you have acute hepatitis or liver failure.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrecipitated Withdrawal: \u003c\/strong\u003eTaking Naltrexone while opioids are still in your system can result in sudden withdrawal symptoms. A 7-10 day opioid-free period is recommended before initiation.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiver Considerations:\u003c\/strong\u003e Regular liver function tests are recommended, as Naltrexone can affect liver enzymes.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEmergency Situations:\u003c\/strong\u003e Inform medical personnel of Naltrexone use in emergency situations, especially where pain management is necessary.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eSide Effects:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCommon Side Effects:\u003c\/strong\u003e May include nausea, headache, dizziness, fatigue, and insomnia. These effects are typically mild and transient.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSerious Side Effects:\u003c\/strong\u003e Rarely, some individuals may experience liver toxicity, manifested through symptoms such as dark urine, persistent nausea\/vomiting, right-sided abdominal pain, or jaundice. Immediate medical attention is required if these occur.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllergic Reactions:\u003c\/strong\u003e Seek immediate medical help if signs of a severe allergic reaction occur, such as rash, itching\/swelling (especially of the face\/tongue\/throat), severe dizziness, or difficulty breathing.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBy choosing Naltrexone Hydrochloride 50 mg Film-Coated Tablets from Accord Healthcare, you are investing in a scientifically sound and supportive strategy for achieving abstinence and maintaining recovery. Trust in Accord Healthcare's commitment to excellence and patient-centered care to guide you on your path to wellness.\u003c\/p\u003e","brand":"Accord Healthcare","offers":[{"title":"Default Title","offer_id":51828052787568,"sku":"16729-0081-10","price":93.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Naltrexone-Hydrochloride-50-mg.jpg?v=1737995626"},{"product_id":"naltrexone-hydrochloride-tablets-50-mg","title":"Naltrexone Hydrochloride Tablets 50 mg, 30 Count (RX)","description":"\u003cp\u003eNaltrexone Hydrochloride Tablets are a medication used primarily to treat alcohol and opioid dependence. Naltrexone works by blocking the effects of opioids in the brain, which helps reduce cravings and prevent relapse. For alcohol dependence, it can help decrease the desire to drink and prevent heavy drinking.\u003c\/p\u003e\n\u003cp\u003eThe medication is usually part of a comprehensive treatment plan that includes counseling and support. It's important for individuals to be opioid-free before starting naltrexone to avoid withdrawal symptoms. As with all medications, it should be taken under the supervision of a healthcare professional to ensure safety and effectiveness.\u003c\/p\u003e\n\u003cp\u003eNaltrexone Hydrochloride Tablets by Sun Pharmaceuticals offer a reliable solution for those seeking to manage addiction. Each tablet contains 50 mg of active ingredient designed to support treatment programs for alcohol and opioid dependence.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUses:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNaltrexone is primarily used to:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAssist in the treatment of alcohol dependence\u003c\/li\u003e\n\u003cli\u003eSupport the prevention of relapse in opioid dependence after detoxification\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDosage:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eStandard dosage is 50 mg once daily.\u003c\/li\u003e\n\u003cli\u003eDosage may vary based on medical guidance and specific treatment goals.\u003c\/li\u003e\n\u003cli\u003eEnsure strict adherence to the prescribed regimen.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eCDC Guidelines:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe CDC recommends using naltrexone as part of a broader addiction treatment program, which may include counseling, social support, and lifestyle changes. It's crucial to initiate treatment in a monitored environment.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDetails and Features:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrength:\u003c\/strong\u003e 50 mg per tablet\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCount:\u003c\/strong\u003e 30 tablets per bottle\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBrand:\u003c\/strong\u003e Sun Pharmaceuticals\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNDC:\u003c\/strong\u003e 47335-0326-83\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMechanism of Action:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNaltrexone is an opioid antagonist that works by blocking opioid receptors in the brain. This prevents the euphoric effects of opioids and reduces cravings and urges associated with alcohol consumption.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDirections:\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eTake orally with water, once daily or as directed by a healthcare provider.\u003c\/li\u003e\n\u003cli\u003eCan be taken with or without food.\u003c\/li\u003e\n\u003cli\u003eConsistent daily intake is crucial for effectiveness.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cstrong\u003eWarnings:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNot suitable for individuals with opioid dependency without detoxification.\u003c\/li\u003e\n\u003cli\u003eDo not use if there is a risk of opioid withdrawal.\u003c\/li\u003e\n\u003cli\u003eLiver function should be monitored regularly.\u003c\/li\u003e\n\u003cli\u003eContraindicated in patients with acute hepatitis or liver failure.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSide Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCommon side effects may include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNausea or vomiting\u003c\/li\u003e\n\u003cli\u003eHeadache\u003c\/li\u003e\n\u003cli\u003eDizziness\u003c\/li\u003e\n\u003cli\u003eFatigue or insomnia\u003c\/li\u003e\n\u003cli\u003eJoint or muscle pain\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eConsult Healthcare Provider:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBefore starting naltrexone, consult with a healthcare provider to assess suitability, especially if there are existing health concerns or medications. Report any adverse effects immediately, focusing on symptoms related to liver function or allergic reactions.\u003c\/p\u003e","brand":"Sun Pharmaceuticals","offers":[{"title":"Default Title","offer_id":52264717320560,"sku":"47335-0326-83","price":59.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Naltrexone-Hydrochloride-Tablets-50-mg.jpg?v=1747053467"},{"product_id":"naltrexone-hydrochloride-tablets-50-mg-sun-pharmaceuticals","title":"Naltrexone Hydrochloride Tablets 50 mg, 100 Count (RX)","description":"Naltrexone hydrochloride tablets are an oral medication prescribed for the treatment of opioid and alcohol dependence. As a pure opioid antagonist, naltrexone blocks the pleasurable and sedative effects associated with alcohol and opioids, helping to reduce cravings. It is not an opioid, is non-addictive, and does not cause withdrawal symptoms upon discontinuation.\n\u003cp\u003eNaltrexone Hydrochloride Tablets 50 mg by Sun Pharmaceuticals provide effective, clinically proven support for individuals seeking long-term recovery from opioid dependence or alcohol dependence. Manufactured to rigorous standards, each bottle contains 100 tablets, offering convenient, consistent, and affordable access for ongoing treatment. Supported by decades of therapeutic use, Naltrexone blocks the effects of opioids and reduces cravings for alcohol, empowering individuals on their journey to sobriety.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eWhat It Is Used For\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eNaltrexone Hydrochloride is indicated for:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eThe management and prevention of relapse in patients with opioid dependence (following opioid detoxification).\u003c\/li\u003e\n\u003cli\u003eTreatment of alcohol dependence, reducing alcohol cravings and helping to maintain abstinence.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eNote:\u003c\/strong\u003e Naltrexone should be used as part of a comprehensive treatment program, including counseling and psychosocial support.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eDetails and Features\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eActive Ingredient:\u003c\/strong\u003e Naltrexone Hydrochloride 50 mg per tablet\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eManufacturer:\u003c\/strong\u003e Sun Pharmaceuticals\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePackage Size:\u003c\/strong\u003e 100 count (bottle)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Oral tablet, scored for flexible dosing\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuality Assured:\u003c\/strong\u003e Manufactured under stringent GMP guidelines\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e Yes\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFeatures:\u003c\/strong\u003e\n\u003cul\u003e\n\u003cli\u003eProven efficacy in relapse prevention\u003c\/li\u003e\n\u003cli\u003eEasy, once-daily oral dosing\u003c\/li\u003e\n\u003cli\u003eNon-addictive and non-narcotic\u003c\/li\u003e\n\u003cli\u003eConvenient bottle for long-term therapy\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eDirections for Use\u003c\/strong\u003e\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003eTake exactly as prescribed by your healthcare provider.\u003c\/li\u003e\n\u003cli\u003eThe usual adult dose: \u003cstrong\u003e50 mg tablet taken once daily by mouth\u003c\/strong\u003e. Dosage may vary based on patient response and physician direction.\u003c\/li\u003e\n\u003cli\u003eSwallow tablets whole with a glass of water. May be taken with or without food.\u003c\/li\u003e\n\u003cli\u003eDo not attempt to self-medicate or adjust dosage without medical supervision.\u003c\/li\u003e\n\u003cli\u003eNaltrexone is most effective when used in conjunction with a structured recovery program.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch3\u003e\u003cstrong\u003eDosage\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdults (Opioid\/Alcohol Dependence):\u003c\/strong\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cem\u003eTypical dose:\u003c\/em\u003e 50 mg once daily, or as directed by your doctor.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMissed Dose:\u003c\/strong\u003e Take as soon as remembered. If it is almost time for your next dose, skip the missed dose. Do not double up to make up for a missed dose.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChildren:\u003c\/strong\u003e Not typically recommended for use in individuals under 18 years old unless directed by a physician.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eAllergies\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eDo not use\u003c\/strong\u003e if you have:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eKnown hypersensitivity to Naltrexone Hydrochloride or any component of this product.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSigns of allergic reaction:\u003c\/strong\u003e Rash, itching, swelling, severe dizziness, or trouble breathing — seek immediate medical attention.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eDrug Interactions\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eBe sure to inform your doctor about all medications and supplements you are taking, especially:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eOpioid medications (e.g., codeine, hydrocodone, oxycodone, morphine, heroin)\u003c\/li\u003e\n\u003cli\u003eCertain cough\/cold medications, antidiarrheal drugs, or pain relievers containing opioids\u003c\/li\u003e\n\u003cli\u003eDisulfiram (used for alcohol dependence)\u003c\/li\u003e\n\u003cli\u003eOther medications affecting the liver\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eNote:\u003c\/strong\u003e Naltrexone will block the effects of opioid medications. Do not use opioids while taking this medication. Doing so may result in sudden withdrawal symptoms.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eSide Effects and Warnings\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003ePossible Side Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNausea, vomiting, stomach pain\u003c\/li\u003e\n\u003cli\u003eHeadache, dizziness, tiredness\u003c\/li\u003e\n\u003cli\u003eAnxiety, insomnia, or restlessness\u003c\/li\u003e\n\u003cli\u003eMuscle or joint pain\u003c\/li\u003e\n\u003cli\u003eDecreased appetite\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSerious Side Effects (Seek medical attention immediately):\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLiver toxicity: Yellowing eyes\/skin, dark urine, upper belly pain\u003c\/li\u003e\n\u003cli\u003eSevere allergic reactions: Rash, itching\/swelling, difficulty breathing\u003c\/li\u003e\n\u003cli\u003eInjection site reaction (if using the injectable form)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eWarnings:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDo not use Naltrexone if you are currently dependent on opioids\u003c\/strong\u003e or have not completed detoxification; can precipitate acute withdrawal.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiver Risk:\u003c\/strong\u003e Use with caution in patients with liver disease; regular liver function monitoring is recommended.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePregnancy\/Breastfeeding:\u003c\/strong\u003e Use only if benefits outweigh potential risks; consult your physician.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMedical Alert:\u003c\/strong\u003e Notify healthcare providers you are taking Naltrexone before surgery; special protocols may be needed for pain management.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eDisclaimer\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eNaltrexone Hydrochloride Tablets 50 mg by Sun Pharmaceuticals\u003c\/strong\u003e are available by prescription only. Use strictly as directed by your healthcare provider. Always consult your doctor before starting, stopping, or changing your medication regimen.\u003c\/p\u003e","brand":"Sun Pharmaceuticals","offers":[{"title":"Default Title","offer_id":52264758739312,"sku":"47335-0326-88","price":185.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/47335-0326-88.jpg?v=1747055197"},{"product_id":"naltrexone-tablets-50-mg-precision-dose-100-count","title":"Naltrexone 50 mg Tablets 100 Count (RX)","description":"\u003ch1\u003eNaltrexone 50 mg Tablets\u003c\/h1\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003eNaltrexone is a \u003cstrong\u003elong-acting opioid receptor antagonist\u003c\/strong\u003e (a pure opiate blocker) available as a 50 mg oral tablet (brand names: ReVia®, Depade®, generics) and as a 380 mg monthly gluteal injection (Vivitrol®). It has high affinity for μ-opioid receptors (and to a lesser degree δ\/κ receptors) but no agonist effects. In practice, naltrexone \u003cstrong\u003eblocks the effects of opioids\u003c\/strong\u003e (preventing their euphoria and analgesia) and \u003cstrong\u003edampens alcohol’s rewarding effects\u003c\/strong\u003e by occupying opioid receptors released by endorphins. For example, a single 50 mg dose will block heroin or prescription opioid effects for ~24 hours. Naltrexone does not relieve pain or cause addiction itself, but displaces opioids; if opioids are still in the body, taking naltrexone will precipitate withdrawal.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003eUses (Indications)\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOpioid Use Disorder (OUD):\u003c\/strong\u003e Naltrexone is FDA-approved for \u003cstrong\u003epreventing relapse in opioid-dependent patients\u003c\/strong\u003e who have completed detox and are opioid-free. It is prescribed in Medication-Assisted Treatment along with counseling. (Extended-release naltrexone IM is an alternative for patients who have difficulty with daily pills.)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAlcohol Use Disorder (AUD):\u003c\/strong\u003e FDA-approved to \u003cstrong\u003ereduce heavy drinking\u003c\/strong\u003e and relapse in alcohol-dependent patients. It is used \u003cem\u003eafter\u003c\/em\u003e alcohol detox is complete (to avoid vomiting), usually as 50 mg once daily. Naltrexone \u003cstrong\u003ereduces alcohol craving and reward\u003c\/strong\u003e by blocking alcohol-induced endorphin effects. It is \u003cem\u003enot\u003c\/em\u003e disulfiram – it does not cause nausea with drinking, but simply makes drinking less pleasurable.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOther approved\/experimental uses:\u003c\/strong\u003e A fixed-dose combo of naltrexone+bupropion is FDA-approved for obesity (as Contrave®). Off-label, naltrexone has been explored for impulse-control and eating disorders. Notably, \u003cstrong\u003elow-dose naltrexone (LDN)\u003c\/strong\u003e (~1–5 mg daily) is used experimentally for chronic pain and autoimmune conditions (e.g. fibromyalgia, Crohn’s disease, multiple sclerosis).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eNaltrexone 50 mg\u003c\/strong\u003e \u003cstrong\u003eTablets \u003c\/strong\u003eare a prescription medication used primarily for:\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eAlcohol dependence:\u003c\/strong\u003e To help people who have stopped drinking alcohol remain abstinent.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOpioid dependence:\u003c\/strong\u003e To aid in the maintenance of opioid abstinence, following detoxification.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eHow Naltrexone Works\u003c\/h2\u003e\n\u003cp\u003eNaltrexone acts as a \u003cstrong\u003ecompetitive antagonist at opioid receptors\u003c\/strong\u003e. By binding μ-opioid receptors, it \u003cstrong\u003eblocks any opioid agonist\u003c\/strong\u003e (heroin, morphine, oxycodone, etc.) from activating them. This prevents the usual opioid effects of euphoria, pain relief and respiratory depression. In clinical terms, taking naltrexone after opioids will precipitate immediate withdrawal, so patients must be opioid-free before starting.\u003c\/p\u003e\n\u003cp\u003eFor alcohol dependence, naltrexone’s blockade of opioid receptors interferes with alcohol’s reward circuitry. Alcohol normally triggers release of endogenous opioids (endorphins) that reinforce drinking. Naltrexone \u003cstrong\u003eblunts that endogenous opioid surge\u003c\/strong\u003e, thus reducing craving and the “reward” from alcohol. It modestly increases abstinence rates when combined with counseling.\u003c\/p\u003e\n\u003cp\u003ePharmacokinetics: Oral naltrexone is well absorbed (peak ~1–2 hours) but has ~5–40% bioavailability due to first-pass metabolism. It is metabolized to active 6-β-naltrexol and cleared mostly by the kidney. The 50 mg dose sustains μ-receptor blockade for ~24 hours; its terminal half-life is ~4 hours (75% of drug gone by 24h). The IM depot (380 mg) provides blockade for ~4 weeks.\u003c\/p\u003e\n\u003ch2\u003eDosage and Administration\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e50 mg oral tablet\u003c\/strong\u003e: The usual maintenance dose for both AUD and OUD is \u003cstrong\u003e50 mg once daily\u003c\/strong\u003e. Treatment generally starts at 25 mg (to test tolerance) and then increases to 50 mg after 1–2 days if no withdrawal or side effects occur. It can be taken with or without food (with meals may reduce GI upset).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eOpioid detox requirement:\u003c\/strong\u003e Crucially, patients must be fully opioid-free (about 7–10 days after short-acting opioids) before starting naltrexone. Otherwise, naltrexone will trigger withdrawal. In practice a small “naloxone challenge” can verify the absence of opioids.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eIM Injection (380 mg):\u003c\/strong\u003e An extended-release monthly intramuscular injection is also available. It is administered deep in the gluteal region every 4 weeks. This depot is often used for patients who may not reliably take daily pills. The injection produces effective blockade for ~4 weeks and improves compliance in some patients.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eAlcohol dependence:\u003c\/strong\u003e Similarly, 50 mg daily is standard, given in supervised doses or with family support. Therapy should emphasize continued sobriety; naltrexone will help attenuate heavy drinking if relapse occurs.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003ePediatric use:\u003c\/strong\u003e Naltrexone is not approved for children or adolescents.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eSpecial populations:\u003c\/strong\u003e Dose adjustment is generally not required in mild\/moderate renal impairment. \u003cem\u003eHepatic caution:\u003c\/em\u003e Because naltrexone is hepatically metabolized, it should be avoided in acute hepatitis or liver failure. (Liver enzyme monitoring is advisable.) Withdrawal precautions apply if used in pregnant opioid users.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eLow-Dose Naltrexone (LDN):\u003c\/strong\u003e A very low nightly dose (typically 1.5–4.5 mg) is used off-label for pain\/autoimmune disorders. This “intermittent” blockade of opioid growth factor receptors may upregulate endorphins and modulate immune function. Protocols vary, but a common regimen is one 3 or 4.5 mg dose taken at bedtime. This use is supported by small trials and patient reports showing reductions in pain and fatigue (e.g. in fibromyalgia, Crohn’s, MS). It is not FDA-approved, but many integrative physicians prescribe LDN for refractory chronic conditions.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSide Effects\u003c\/h2\u003e\n\u003cp\u003eNaltrexone’s side effects are generally mild and dose-related. Common adverse effects (≥10% incidence) include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eGastrointestinal:\u003c\/strong\u003e \u003cem\u003eNausea\u003c\/em\u003e (up to ~33%), \u003cem\u003evomiting\u003c\/em\u003e (~11–14%), \u003cem\u003ediarrhea\u003c\/em\u003e, \u003cem\u003eabdominal cramps\u003c\/em\u003e. Taking with food or at bedtime may ease nausea.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eCNS:\u003c\/strong\u003e \u003cem\u003eHeadache\u003c\/em\u003e (~25%), \u003cem\u003einsomnia\u003c\/em\u003e (10–15%), \u003cem\u003edizziness\u003c\/em\u003e, \u003cem\u003eanxiety\u003c\/em\u003e (~12%), \u003cem\u003efatigue or low energy\u003c\/em\u003e, \u003cem\u003esleep disturbances\u003c\/em\u003e. These often lessen after a few weeks.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eAppetite\/weight:\u003c\/strong\u003e Decreased appetite (∼14%), which may be desirable in some overweight patients.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eMusculoskeletal:\u003c\/strong\u003e Muscle\/joint pain, back pain, or cramps are reported (6–12%).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003ePsychiatric:\u003c\/strong\u003e Mood changes can occur. In trials, depression was reported (~8%). Rare suicidal ideation has been noted (slightly above placebo rates). Patients with severe mental illness should be monitored closely for worsening mood or suicidality.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eAllergies:\u003c\/strong\u003e Allergic reactions are rare. If rash, itching, or angioedema occur, discontinue naltrexone. A handful of urticarial\/angioedema cases have been reported.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eInjection site (Vivitrol only):\u003c\/strong\u003e The monthly IM formulation often causes injection-site pain, swelling, nodules or bruising (up to ~69%), which is usually mild and resolves.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eHepatic:\u003c\/strong\u003e Though uncommon at normal doses, \u003cem\u003eliver toxicity\u003c\/em\u003e is a serious potential effect. High doses (\u0026gt;300 mg\/day) have caused hepatic injury. Even patient’s long-term use can elevate transaminases. Liver function tests should be checked periodically, and naltrexone avoided (or used very cautiously) in active liver disease.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003ePrecipitated withdrawal:\u003c\/strong\u003e The most important “side effect” is precipitated opioid withdrawal. If naltrexone is taken while opioids are in the system, it can cause \u003cstrong\u003eacute withdrawal\u003c\/strong\u003e (nausea, vomiting, sweating, tachycardia, anxiety, muscle aches, piloerection, etc.). Hence, proper detoxification \u003cem\u003eand\u003c\/em\u003e a naloxone challenge are recommended before starting therapy.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eOther:\u003c\/strong\u003e Dry mouth, diarrhea, and rare cases of elevated CPK or heart rate changes have been documented. If patients experience unusual symptoms (e.g. severe abdominal pain, jaundice, chest pain, or seizures), naltrexone should be stopped and medical evaluation sought.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIn summary, naltrexone (50 mg tablets) is a key “blocker” in addiction medicine – it prevents opioid euphoria and reduces alcohol craving. It is taken once daily as part of a comprehensive relapse prevention plan. Side effects are mostly gastrointestinal or headache and tend to be transient. The biggest risks are liver injury (dose-dependent) and precipitating withdrawal if misused. Low-dose naltrexone (1–5 mg) is an alternative regimen under research, thought to modulate immune factors, with generally mild side effects.\u003c\/p\u003e\n\u003ch3\u003eDetails and Features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eActive Ingredient:\u003c\/strong\u003e Naltrexone Hydrochloride 50 mg per tablet\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eManufacturer:\u003c\/strong\u003e Sun Pharmaceuticals\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePackage Size:\u003c\/strong\u003e 100 count (bottle)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Oral tablet, scored for flexible dosing\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuality Assured:\u003c\/strong\u003e Manufactured under stringent GMP guidelines\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e Yes\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFeatures:\u003c\/strong\u003e\n\u003cul\u003e\n\u003cli\u003eProven efficacy in relapse prevention\u003c\/li\u003e\n\u003cli\u003eEasy, once-daily oral dosing\u003c\/li\u003e\n\u003cli\u003eNon-addictive and non-narcotic\u003c\/li\u003e\n\u003cli\u003eConvenient bottle for long-term therapy\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eDirections for Use\u003c\/strong\u003e\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003eTake exactly as prescribed by your healthcare provider.\u003c\/li\u003e\n\u003cli\u003eThe usual adult dose: \u003cstrong\u003e50 mg tablet taken once daily by mouth\u003c\/strong\u003e. Dosage may vary based on patient response and physician direction.\u003c\/li\u003e\n\u003cli\u003eSwallow tablets whole with a glass of water. May be taken with or without food.\u003c\/li\u003e\n\u003cli\u003eDo not attempt to self-medicate or adjust dosage without medical supervision.\u003c\/li\u003e\n\u003cli\u003eNaltrexone is most effective when used in conjunction with a structured recovery program.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch3\u003e\u003cstrong\u003eDosage\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdults (Opioid\/Alcohol Dependence):\u003c\/strong\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cem\u003eTypical dose:\u003c\/em\u003e 50 mg once daily, or as directed by your doctor.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMissed Dose:\u003c\/strong\u003e Take as soon as remembered. If it is almost time for your next dose, skip the missed dose. Do not double up to make up for a missed dose.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChildren:\u003c\/strong\u003e Not typically recommended for use in individuals under 18 years old unless directed by a physician.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eAllergies\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eDo not use\u003c\/strong\u003e if you have:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eKnown hypersensitivity to Naltrexone Hydrochloride or any component of this product.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSigns of allergic reaction:\u003c\/strong\u003e Rash, itching, swelling, severe dizziness, or trouble breathing — seek immediate medical attention.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eDrug Interactions\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eBe sure to inform your doctor about all medications and supplements you are taking, especially:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eOpioid medications (e.g., codeine, hydrocodone, oxycodone, morphine, heroin)\u003c\/li\u003e\n\u003cli\u003eCertain cough\/cold medications, antidiarrheal drugs, or pain relievers containing opioids\u003c\/li\u003e\n\u003cli\u003eDisulfiram (used for alcohol dependence)\u003c\/li\u003e\n\u003cli\u003eOther medications affecting the liver\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eNote:\u003c\/strong\u003e Naltrexone will block the effects of opioid medications. Do not use opioids while taking this medication. Doing so may result in sudden withdrawal symptoms.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eSide Effects and Warnings\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003ePossible Side Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNausea, vomiting, stomach pain\u003c\/li\u003e\n\u003cli\u003eHeadache, dizziness, tiredness\u003c\/li\u003e\n\u003cli\u003eAnxiety, insomnia, or restlessness\u003c\/li\u003e\n\u003cli\u003eMuscle or joint pain\u003c\/li\u003e\n\u003cli\u003eDecreased appetite\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSerious Side Effects (Seek medical attention immediately):\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLiver toxicity: Yellowing eyes\/skin, dark urine, upper belly pain\u003c\/li\u003e\n\u003cli\u003eSevere allergic reactions: Rash, itching\/swelling, difficulty breathing\u003c\/li\u003e\n\u003cli\u003eInjection site reaction (if using the injectable form)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eWarnings:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDo not use Naltrexone if you are currently dependent on opioids\u003c\/strong\u003e or have not completed detoxification; can precipitate acute withdrawal.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiver Risk:\u003c\/strong\u003e Use with caution in patients with liver disease; regular liver function monitoring is recommended.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePregnancy\/Breastfeeding:\u003c\/strong\u003e Use only if benefits outweigh potential risks; consult your physician.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMedical Alert:\u003c\/strong\u003e Notify healthcare providers you are taking Naltrexone before surgery; special protocols may be needed for pain management.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eNaltrexone Tablets 50 mg by are available by prescription only. Use strictly as directed by your healthcare provider. Always consult your doctor before starting, stopping, or changing your medication regimen.\u003c\/p\u003e","brand":"Precision Dose Inc.","offers":[{"title":"Default Title","offer_id":53474117026160,"sku":"68094-909-50P","price":139.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Naltrexone-Hydrochloride-Tablets-50-mg-Precision-Dose.jpg?v=1774957737"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/collections\/Naltrexone_Hydrochloride.jpg?v=1774969932","url":"https:\/\/www.mountainside-medical.com\/collections\/naltrexone\/naltrexone-hydrochloride-usp+doctor-only.oembed","provider":"Mountainside Medical","version":"1.0","type":"link"}