{"title":"Sodium Bicarbonate Injections","description":"\u003cp\u003eDiscover premium \u003cstrong\u003eSodium Bicarbonate Injections\u003c\/strong\u003e—your trusted solution for acidosis treatment, pH balance, and metabolic correction. Our pharmaceutical-grade sodium bicarbonate offers rapid relief from severe metabolic acidosis, renal insufficiency, and cardiac arrest. Ideal for hospital, emergency, and clinical settings, these sterile injections help restore electrolyte balance, improve blood gas levels, and support critical care interventions. Ensure safe, effective patient management with our top-quality sodium bicarbonate injection treatments.\u003c\/p\u003e","products":[{"product_id":"sodium-bicarbonate-for-injection-50-ml-vial","title":"Sodium Bicarbonate 8.4% Injection 50 ml Vial, 25\/pack (Rx)","description":"\u003cp\u003eSodium bicarbonate is a medication used to treat conditions caused by excessive acidity in the blood or urine, such as certain types of acidosis (a condition in which there is too much acid in the body). It is also used to relieve symptoms of heartburn, indigestion, and acid reflux. Sodium bicarbonate works by neutralizing excess acid in the body, helping to restore a more balanced pH level. The 8.4% solution is typically used for severe acidosis or in emergency situations. It is administered by injection into a vein or muscle by a healthcare provider.\u003c\/p\u003e\n\u003cp\u003eExcela Sodium Bicarbonate 8.4% for Injection is a sterile, nonpyrogenic, aqueous solution of sodium bicarbonate (NaHCO3) in water for injection. Each mL of Excela Sodium Bicarbonate 8.4% for Injection contains 8.4 mg of sodium bicarbonate and 0.5 mg of potassium chloride (KCl) in Water for Injection. Sodium bicarbonate, a white, crystalline powder, is an alkalinizing agent and buffer. It is soluble in water and slightly soluble in alcohol. The pH of a 1% solution is 10.5. The pKa of sodium bicarbonate is 8.3. The chemical name for sodium bicarbonate is sodium hydrogen carbonate. The structural formula is NaHCO3. The molecular weight is 84.01. Potassium chloride, a white, crystalline powder, is a potassium salt. It is soluble in water and slightly soluble in alcohol. The pH of a 1% solution is 7.0. The pKa of potassium chloride is 6.3. The chemical name for potassium chloride is potassium hydrogen chloride. The structural formula is KCl. The molecular weight is 74.55. Excela Sodium Bicarbonate 8.4% for Injection is indicated for the treatment of metabolic acidosis in patients with renal failure. Excela Sodium Bicarbonate 8.4% for Injection is also indicated for the treatment of metabolic acidosis in patients with cardiac arrest.\u003c\/p\u003e\n\u003cp\u003eExcela Pharma Sciences 51754-5001-04 Sodium Bicarbonate Injection, USP is indicated in the treatment of metabolic acidosis which may occur in severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or severe dehydration, extracorporeal circulation of blood, cardiac arrest and severe primary lactic acidosis.\u003c\/p\u003e\n\u003cp\u003eEach mL contains sodium bicarbonate, 84 mg. 2 m0smol \/ mL (calc.). pH 7.8 (7.0 to 8.5). Single-dose container. Do not resterilize. For intravenous use.\u003c\/p\u003e\n\u003cp\u003eDoes NOT contain any bacteriostatic preservatives.\u003c\/p\u003e\n\u003cp\u003eBrand: Excela Pharma \u003cbr\u003eSize: 50 mL (1 mEq\/ mL) - 4.2 grams (84 mg\/mL) \u003cbr\u003eNDC:  51754-5001-04 \u003cbr\u003eType: Sterile Single-dose USP   \u003c\/p\u003e\n\u003cp\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eHow supplied: 50 mL single-dose vial\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eOrange Book Rating: AP\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eDescription: Clear, sterile, nonpyrogenic, hypertonic solution\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"Excela Pharma Sciences","offers":[{"title":"Default Title","offer_id":5648318340,"sku":"51754-5001-04","price":570.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/products\/51754-5001-5.jpg?v=1709579700"},{"product_id":"hospira-sodium-bicarbonate-for-injection-8_4-pfizer","title":"Sodium Bicarbonate Injection 8.4% Hospira 50 mL Vials 25\/pack (Rx)  Exp 3\/31\/27","description":"\u003ch1\u003eSodium Bicarbonate Injection 8.4%\u003c\/h1\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003eSodium bicarbonate 8.4% is a sterile, preservative-free \u003cstrong\u003ehypertonic\u003c\/strong\u003e IV solution of sodium bicarbonate (NaHCO₃) at 84 mg\/mL (which equals 1 mEq of Na⁺ and 1 mEq of HCO₃⁻ per mL). It is intended \u003cstrong\u003efor single-dose intravenous use\u003c\/strong\u003e and has a pH in the range of about 7.0–8.5\u003c\/span\u003e.\u003c\/p\u003e\n\u003cp\u003eCurrent Stock Expiration : 3\/31\/27\u003c\/p\u003e\n\u003cp\u003eSodium Bicarbonate for Injection 8.4% is a sterile, non-pyrogenic solution formulated for intravenous use in clinical and hospital settings. Each 50 mL vial contains sodium bicarbonate at a concentration of 8.4% (1 mEq\/mL), designed to correct metabolic acidosis and treat medical emergencies that require rapid pH regulation. Supplied by Pfizer Injectables, this trusted product comes in a pack of 25 convenient single-use vials for consistent dosing and sterility.\u003c\/p\u003e\n\u003ch2\u003e\u003cspan class=\"VODHU pdMy8\"\u003eHow it works:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003eIn the bloodstream it dissociates into Na⁺ and HCO₃⁻. The bicarbonate serves as a base buffer: it combines with excess H⁺ ions (acid) to form carbonic acid, which rapidly converts to CO₂ (exhaled by the lungs), thus \u003cstrong\u003eraising blood pH and reversing acidosis\u003c\/strong\u003e. The sodium helps restore extracellular fluid volume and electrolytes.\u003c\/span\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan class=\"VODHU pdMy8\"\u003eUses:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003e8.4% sodium bicarbonate is used to treat serious acid–base disturbances and related conditions. Typical indications include:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003cstrong\u003eSevere metabolic acidosis\u003c\/strong\u003e – for example due to renal failure, diabetic ketoacidosis, shock, severe dehydration, lactic acidosis, or during cardiopulmonary resuscitation.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003cstrong\u003eCardiac arrest\u003c\/strong\u003e – as part of advanced life support to counter acidosis during resuscitation.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003cstrong\u003eExtracorporeal circulation\u003c\/strong\u003e – to buffer blood in procedures like dialysis or bypass if acidosis occurs. \u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003cstrong\u003ePoisonings\u003c\/strong\u003e – to treat aspirin (salicylate) or methanol poisoning by alkalinizing blood\/urine.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"VODHU pdMy8\"\u003eHemolytic reactions with risk of kidney injury – to alkalinize the urine and reduce nephrotoxicity from hemoglobin break-down products.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003cstrong\u003eSevere diarrhea or gastrointestinal losses\u003c\/strong\u003e – when bicarbonate is lost and acidosis ensues.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003cstrong\u003eHyperkalemia\u003c\/strong\u003e – a common emergency use: infusing bicarbonate raises blood pH and shifts potassium into cells, helping to lower serum K⁺ levels rapidly. (Example: one 50 mL ampule of ~8.4% solution contains ≈50 mEq bicarbonate; given IV over 5–10 minutes it can mitigate life-threatening hyperkalemia for 1–2 hours.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\u003cspan class=\"VODHU pdMy8\"\u003eAdministration:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003e This is \u003cstrong\u003eIV-only\u003c\/strong\u003e and must be ordered\/dosed by a healthcare professional. It can be given as a bolus injection or diluted in IV fluids, depending on clinical needs. Large volumes (and therefore sodium loads) must be managed carefully. Standard adult packaging is often 50 mL vials (50 mEq each) or larger containers. The solution must be \u003cstrong\u003eclear\u003c\/strong\u003e before use; if any precipitate or crystals are seen (they can form at cold temperatures), warm and agitate the solution until clear. Only administer if the vial is intact and uncloudy. Any unused portion of a single-dose vial should be discarded.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003cstrong\u003eCompatibility:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003eDo not mix sodium bicarbonate directly with calcium-containing IV solutions (calcium salts will precipitate). Catecholamine infusions (e.g. norepinephrine, dobutamine) and some other drugs are incompatible and should not be run through the same line with bicarbonate. Always use aseptic technique and check compatibility when adding any medications to bicarbonate.\u003c\/span\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003eDetails \u0026amp; Features\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eConcentration:\u003c\/strong\u003e 8.4% Sodium Bicarbonate (1 mEq\/mL)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVolume:\u003c\/strong\u003e 50 mL per vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePackaging:\u003c\/strong\u003e 25 single-dose vials per box\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSterile \u0026amp; Non-Pyrogenic:\u003c\/strong\u003e Ideal for IV administration\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLatex-Free Packaging:\u003c\/strong\u003e Reduces risk of allergic reactions\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTransparent, Colorless Solution:\u003c\/strong\u003e Allows for easy inspection prior to administration\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReady-to-Use:\u003c\/strong\u003e No dilution required for most adult dosing scenarios\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTrusted Manufacturer:\u003c\/strong\u003e Pfizer Injectables ensures quality and consistency\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eDirections\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eInspection:\u003c\/strong\u003e Ensure that the solution is clear and vial is undamaged before use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAseptic Technique:\u003c\/strong\u003e Use sterile equipment and procedures during preparation and administration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdministration:\u003c\/strong\u003e Administer by slow intravenous injection or infusion under the supervision of a healthcare professional. Follow specific protocols for emergency interventions or in combination therapy as directed by a physician.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiscard Unused Portion:\u003c\/strong\u003e Single-use vials; discard any remaining solution after initial use.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eDosage\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIndividualized Dosage:\u003c\/strong\u003e Dosage must be calculated based on the patient's clinical condition, lab results, and physician’s instructions. A typical adult dose for acidosis may range from 1 to 2 mEq\/kg, administered slowly IV.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePediatric Dose:\u003c\/strong\u003e Carefully calculated by a physician according to patient needs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInfusion Rates:\u003c\/strong\u003e IV administration should be slow and closely monitored, especially in children and the elderly.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eAlways consult official prescribing information and a healthcare provider for precise dosing guidelines tailored to each patient.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eAllergies\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypersensitivity:\u003c\/strong\u003e Not common, but inform your healthcare provider if you have allergies to sodium bicarbonate or any ingredients in the product.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLatex-Free:\u003c\/strong\u003e Packaging is free from latex to minimize risk of allergic reactions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eDrug Interactions\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePotential Interactions:\u003c\/strong\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiac Glycosides (e.g., Digoxin):\u003c\/strong\u003e Increased risk of toxicity due to elevated pH.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCorticosteroids or Corticotropin:\u003c\/strong\u003e May elevate sodium retention.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTetracyclines, Methenamine Compounds:\u003c\/strong\u003e Decreased effectiveness or altered drug metabolism.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConcurrent Infusions:\u003c\/strong\u003e Monitor pH and compatibility with other IV solutions or medications.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eReview all medications with your healthcare provider or pharmacist before use.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eSide Effects or Warnings\u003c\/h2\u003e\n\u003ch3\u003eSide Effects\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eLocal Reactions:\u003c\/strong\u003e Pain, redness, or inflammation at the injection site\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystemic Effects:\u003c\/strong\u003e Metabolic alkalosis, hypernatremia (high sodium), hypokalemia (low potassium), tetany, muscle twitching, or seizures with overdose or rapid administration\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFluid Overload:\u003c\/strong\u003e Especially in patients with compromised cardiac or renal function\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWarnings\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFor Intravenous Use Only:\u003c\/strong\u003e Never administer intra-arterially or intramuscularly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid Overcorrection:\u003c\/strong\u003e Administer cautiously to avoid serious metabolic imbalance.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClose Monitoring Required:\u003c\/strong\u003e Frequent monitoring of blood gases, electrolytes, and patient clinical status is mandatory.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpecial Populations:\u003c\/strong\u003e Use with caution in children, elderly, or those with renal\/cardiac dysfunction or hypertension.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePregnancy \u0026amp; Nursing:\u003c\/strong\u003e Use only if clearly needed and prescribed by a physician.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eStorage\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eStore at Controlled Room Temperature (20°-25°C\/68°-77°F)\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eDo not freeze. Discard if solution is cloudy, discolored, or contains particulates.\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003eSodium Bicarbonate 8.4% is a potent alkalinizing agent (“alkali”) used mainly for acute, severe acidosis or hyperkalemia under medical supervision. It redistributes acid–base balance by buffering excess hydrogen ions. Because of its high sodium and osmolar content, it must be used carefully (only in appropriate situations) and only under professional guidance, with close lab monitoring.\u003c\/span\u003e\u003c\/p\u003e","brand":"Pfizer Injectables","offers":[{"title":"Default Title","offer_id":5649603716,"sku":"0409-6625-14","price":389.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Sodium-Bicarbonate-For-Injection-8.4_-Hospira.jpg?v=1764073487"},{"product_id":"sodium-bicarbonate-for-injection-8-4-10ml-vial-25-tray-exela-rx","title":"Sodium Bicarbonate Injection 8.4% Dose IV 10 mL Vial (Rx)","description":"\u003ch2\u003ePowerful Life-Saving Alkali for Metabolic Acidosis, Cardiac Emergencies, and Toxicology Protocols\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSodium Bicarbonate Injection 8.4% by Exela Pharma Sciences\u003c\/strong\u003e delivers immediate, high-impact correction of acute, life-threatening metabolic acidosis, advanced cardiac arrest, drug overdose, renal failure, and electrolyte imbalances. This sterile, preservative-free 10 mL vial (8.4% concentration) offers exact, physician-preferred dosing—making it a crucial crash cart, ICU, ER, anesthesia, and EMS asset trusted by medical professionals nationwide.\u003c\/p\u003e\n\u003cp\u003eSodium Bicarbonate Injection 8.4% 10mL by Exela is a sterile, nonpyrogenic, and highly effective solution designed for the urgent management of life-threatening acid-base imbalances. Trusted by leading hospitals, emergency rooms, and critical care teams, this injectable sodium bicarbonate offers fast, safe, and predictable results when seconds count.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRapid Correction of Acidosis – Emergency pH Balance for Critical Care\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eWhat is Sodium Bicarbonate Injection?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSodium Bicarbonate Injection 8.4%\u003c\/strong\u003e is a concentrated, intravenous (IV) alkalinizing agent used to restore normal blood pH in severe metabolic acidosis, cardiac emergencies, and drug toxicity cases. This crucial medication is commonly administered during CPR, advanced cardiac life support (ACLS), acute renal failure, diabetic ketoacidosis (DKA), and certain poisonings and overdoses.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eEmergency treatment of \u003cem\u003esevere metabolic acidosis\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eCardiac arrest\u003c\/em\u003e and \u003cem\u003eCPR\u003c\/em\u003e protocols (ACLS)\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eDrug overdose\u003c\/em\u003e, poisoning, and toxicity management\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eHyperkalemia\u003c\/em\u003e (high potassium) therapy\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eDiabetic ketoacidosis\u003c\/em\u003e (DKA) and acute\/chronic \u003cem\u003erenal failure\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli\u003eSupport during \u003cem\u003esurgery\u003c\/em\u003e, anesthesia, and critical care\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eOrder Sodium Bicarbonate Injection 8.4% 10 mL IV Vial by Exela Pharma Sciences Now!\u003c\/h2\u003e\n\u003cp\u003eEquip your crash cart, ICU, ER, or EMS team with this vital, hospital-trusted buffer—the proven choice for immediate acidosis correction, poison antidote protocols, and advanced resuscitation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNDC:\u003c\/strong\u003e 51754-5011-04 | \u003cstrong\u003eUPC:\u003c\/strong\u003e 351754501146 \u003cstrong\u003ePrescription required. Hospital\/Professional use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Exela Pharma Sciences","offers":[{"title":"Default Title","offer_id":39706098696264,"sku":"51754-5011-04ea","price":22.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Sodium-Bicarbonate-Injection-8.4_-Exela-Pharma.jpg?v=1766493402"},{"product_id":"pfizer-sodium-bicarbonate-4-2-for-injection-5-ml-x-25-tray","title":"Sodium Bicarbonate 4.2% Injection Single-Dose Vials 5 mL x 25\/Tray by Pfizer (Rx)","description":"\u003cp\u003eSodium Bicarbonate 4.2% Injection is used to treat metabolic acidosis, a condition where the body produces excessive acid or the kidneys cannot remove enough acid, commonly seen in conditions like renal failure or diabetic ketoacidosis. It restores the body's pH balance by neutralizing excess acid in the bloodstream. Additionally, it may be used in emergency situations to manage cardiac arrest and severe hyperkalemia. Administered intravenously, it is a critical tool in acute care settings to stabilize patients quickly.\u003c\/p\u003e\n\u003cp\u003ePfizer 4.2% Sodium Bicarbonate for Injection 5 mL is a sterile, nonpyrogenic, aqueous solution of 4.2% sodium bicarbonate, USP, for intravenous administration. Each milliliter (mL) of the solution contains 42.0 mg of sodium bicarbonate, USP and Water for Injection. Sodium bicarbonate, USP is an alkalinizing agent. The pH of the solution is 7.4 to 8.6. The solution is designed to correct acidosis and to maintain the blood pH within normal limits. It is an electrolyte replenisher.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBenefits for Sodium Bicarbonate Injection:\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSodium bicarbonate injection 4.2% single-dose vials are used as neutralizing agents. Some potential benefits may include:\u003c\/li\u003e\n\u003cli\u003eTreatment of acidosis: Sodium bicarbonate can help restore the acid-base balance in the body by neutralizing excess acid. This can be particularly beneficial for patients with certain medical conditions, such as metabolic acidosis.\u003c\/li\u003e\n\u003cli\u003ePrevention of kidney damage: High levels of acid in the blood can damage the kidneys. By neutralizing excess acid, sodium bicarbonate injection can help protect the kidneys from damage.\u003c\/li\u003e\n\u003cli\u003eImproved heart function: Acidosis can have negative effects on the heart. Sodium bicarbonate can help correct the acid-base imbalance and improve heart function.\u003c\/li\u003e\n\u003cli\u003eRelief of symptoms: Sodium bicarbonate injections can provide relief for symptoms caused by excessive acid in the body. This can include symptoms such as heartburn, indigestion, and sour stomach.\u003c\/li\u003e\n\u003cli\u003eAdjuvant therapy for cancer treatment: Some cancer treatments, such as chemotherapy, can cause acidosis. Sodium bicarbonate injections can be used as adjuvant therapy to reduce the side effects and improve the effectiveness of cancer treatments.\u003c\/li\u003e\n\u003cli\u003eEmergency treatment: Sodium bicarbonate injections can be used as an acute treatment for certain poisonings, such as aspirin overdose, by neutralizing the acidic poison.\u003c\/li\u003e\n\u003cli\u003eEasy administration: Sodium bicarbonate injections are available in single-dose vials, making them convenient to use and administer.\u003c\/li\u003e\n\u003cli\u003eSafe and effective: When used as directed and under the supervision of a healthcare professional, sodium bicarbonate injections are generally safe and effective in treating acidosis and related conditions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDetails and Features\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eActive Ingredient:\u003c\/strong\u003e Sodium Bicarbonate\u003cbr\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 4.2% (42 mg\/mL)\u003cbr\u003e\u003cstrong\u003eVolume:\u003c\/strong\u003e 5 mL per vial\u003cbr\u003e\u003cstrong\u003ePackaging:\u003c\/strong\u003e 25 single-dose vials per tray\u003cbr\u003e\u003cstrong\u003eFormulation:\u003c\/strong\u003e Sterile solution for intravenous use\u003cbr\u003e\u003cstrong\u003eUsage:\u003c\/strong\u003e Treatment of metabolic acidosis, alkalization in specific drug overdoses, and in certain renal conditions\u003cbr\u003e\u003cstrong\u003eManufacturer:\u003c\/strong\u003e Pfizer Injectables\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMechanism of Action\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSodium Bicarbonate acts as a systemic alkalinizing agent, dissociating to provide bicarbonate ions. These ions help to neutralize hydrogen ions and raise the pH of blood and urine. By increasing bicarbonate levels, it aids in reversing states of acidosis and helps to restore normal acid-base balance in the blood. It also assists in enhancing renal clearance of certain drugs by alkalinizing the urine.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWarnings\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFluid and Electrolyte Imbalance:\u003c\/strong\u003e Use with caution in situations where there is a risk of sodium retention or fluid overload, such as renal impairment, heart failure, or hypertension.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAcid-Base Imbalance:\u003c\/strong\u003e Overcorrection of acidosis can result in metabolic alkalosis.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypocalcemia Risks:\u003c\/strong\u003e At high doses or in certain conditions, it may lead to hypocalcemia and associated tetany.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExtravasation Risk:\u003c\/strong\u003e Avoid extravasation, as it may cause tissue necrosis; administer through a secure intravenous line.\u003cbr\u003e\u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePediatrics:\u003c\/strong\u003e Adjust dosage carefully in pediatrics to prevent complications related to rapid pH changes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eSide Effects\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCommon Side Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eInjection site reactions such as pain or irritation\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eMetabolic alkalosis if overused\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eEdema or fluid overload, particularly in predisposed individuals\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSerious Side Effects:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHypernatremia (high sodium levels)\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eMetabolic alkalosis, leading to muscle twitching or cramps, confusion\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eHypocalcemia, potentially leading to muscle spasms or convulsions\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003ePulmonary edema in the setting of volume overload\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdministration and Monitoring\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSodium Bicarbonate 4.2% Injection should be administered by healthcare professionals experienced in managing electrolyte and acid-base disorders. Dosage must be tailored based on laboratory values and the patient's clinical condition. Continuous monitoring of blood gas, serum electrolytes, and acid-base balance is crucial during treatment to prevent complications such as alkalosis. Regular assessments are necessary to determine therapeutic efficacy and to make necessary adjustments to therapy.\u003cbr\u003e\u003c\/p\u003e","brand":"Pfizer Injectables","offers":[{"title":"Default Title","offer_id":39871922307144,"sku":"0409-5555-02","price":395.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Sodium-Bicarbonate-4_2_percent-by-Pfizer.jpg?v=1730743230"},{"product_id":"sodium-bicarbonate-8-4-luer-jet-prefilled-syringes-50-ml-x-10-pack","title":"Sodium Bicarbonate 8.4% Medication Luer-Jet Syringe 50 mL","description":"\u003ch2\u003eGold-Standard Buffer for Emergency, Critical Care, and Cardiac Code Response\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSodium Bicarbonate 8.4% Prefilled Syringe\u003c\/strong\u003e by International Medication Systems is the trusted, hospital-grade solution for rapid correction of severe metabolic acidosis, cardiac arrest, drug toxicity, renal failure, and critical electrolyte imbalances. Each 50 mL Luer-Jet Luer-Lock syringe delivers precise, sterile dosing for immediate IV administration—essential for every crash cart, emergency department, ICU, and EMS protocol.\u003c\/p\u003e\n\u003cp\u003eInternational Medication Systems 3352 Sodium Bicarbonate 8.4% Luer-Jet Prefilled Syringes 50 mL is a highly effective and widely used medication for the treatment of various medical conditions and emergencies. Sodium Bicarbonate 8.4% Syringes are mainly used for restoring and maintaining the normal pH balance of the blood and body fluids in cases of acidosis, which is caused by conditions such as diabetic ketoacidosis and lactic acidosis. The unique Luer-Jet design of these prefilled syringes allows for easy and accurate administration of the medication, making it a favorite among healthcare professionals. The benefits of using Sodium Bicarbonate 8.4% Syringes are numerous, including rapid and precise correction of acidosis, prevention of further tissue damage, and improved patient outcomes. These prefilled syringes also offer convenience and portability, making them ideal for use in emergency situations and critical care units. With its proven effectiveness and ease of use, International Medication Systems 3352 Sodium Bicarbonate 8.4% Luer-Jet Prefilled Syringes 50 mL has become a trusted choice for healthcare providers worldwide.\u003c\/p\u003e\n\u003ch2\u003eOrder Sodium Bicarbonate 8.4% Medication Luer-Jet Prefilled Syringes 50 mL — The Emergency Buffer Solution for Crash Carts, ICU, and EMS\u003c\/h2\u003e\n\u003cp\u003eBe prepared for any code, acidosis, or toxicologic crisis with the gold-standard, hospital-trusted sodium bicarbonate prefilled syringe. Fast, accurate, and reliable—keep every cart, tray, or advanced life support bag equipped and ready.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNDC:\u003c\/strong\u003e 76329-3352-01 | \u003cstrong\u003eUPC:\u003c\/strong\u003e 376329335216 \u003cstrong\u003ePrescription required. Professional\/Clinical use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"International Medication Systems","offers":[{"title":"Default Title","offer_id":40018654658632,"sku":"76329-3352-01ea","price":36.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Sodium-Bicarbonate-8.4_-Luer-Jet-Prefilled-Syringes-50-mL-International-Medication-Systems.jpg?v=1698767432"},{"product_id":"exela-pharma-sodium-bicarbonate-4-2-injection-single-dose-vials-10-ml-x-10-box-rx","title":"Sodium Bicarbonate 4.2% Injection Single-Dose Vials 10 mL x 25\/Box (RX)","description":"\u003cp\u003eExela Pharma Sodium Bicarbonate 4.2% Injection Single-Dose Vials 10 mL is an important medication in the field of medicine that plays a crucial role in treating various medical conditions. This injectable drug contains 4.2% Sodium Bicarbonate, which is a buffer solution used to neutralize acidic conditions in the body. The primary purpose of using Exela Pharma Sodium Bicarbonate 4.2% Injection Vials is to treat conditions such as acidosis, electrolyte imbalances, and certain drug overdoses. When administered intravenously, this medication can quickly restore the body's acid-base balance, ensuring proper functioning of vital organs such as the heart, kidneys, and brain. Furthermore, Sodium Bicarbonate 4.2% Injection Vials can also be used as an adjunct in certain chemotherapy treatments and as a urinary alkalizer to prevent the formation of kidney stones. Its high concentration provides rapid and effective acidosis treatment, making it a preferred choice among healthcare professionals. In conclusion, the use of Exela Pharma Sodium Bicarbonate 4.2% Injection Vials not only offers numerous therapeutic benefits but also showcases the significant role of Sodium Bicarbonate in maintaining optimum bodily functions.\u003c\/p\u003e\n\u003cp\u003eBrand: Exela Pharma Sciences\u003cbr\u003eNDC: 51754-5012-04\u003cbr\u003eStrength: 4.2%\u003cbr\u003eSize: 10 mL\u003cbr\u003eCount: Tray of 25\u003c\/p\u003e","brand":"Exela Pharma Sciences","offers":[{"title":"Default Title","offer_id":40018659049544,"sku":"51754-5012-04","price":350.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Exela-Pharma-Sodium-Bicarbonate-4.2_-Injection-Single-Dose-Vials-10-mL.jpg?v=1698768820"},{"product_id":"sodium-bicarbonate-injection-4-2-single-dose-vials-5-ml-x-25-tray-by-pfizer-rx","title":"Sodium Bicarbonate 4.2% Injection Hospira, Single Dose 5 ml x 25\/Tray (RX)","description":"\u003ch1\u003eSodium Bicarbonate 4.2% Injection\u003c\/h1\u003e\n\u003cp\u003eSodium bicarbonate 4.2% injection is a \u003cstrong\u003esterile intravenous electrolyte solution\u003c\/strong\u003e used to \u003cstrong\u003etreat metabolic acidosis\u003c\/strong\u003e and other conditions requiring systemic alkalinization. The 4.2% solution contains a high concentration of sodium bicarbonate (about 42 mg\/mL, providing 0.5 mEq each of Na⁺ and HCO₃⁻ per mL). This solution is hypertonic and has a near-alkaline pH (~7.0–8.5). When given IV, it \u003cstrong\u003eincreases blood bicarbonate levels, buffers excess hydrogen ions\u003c\/strong\u003e, and \u003cstrong\u003eraises blood pH\u003c\/strong\u003e, thereby correcting acidosis. In the body, bicarbonate combines with hydrogen ions to form carbonic acid, which then converts to carbon dioxide (exhaled by the lungs).\u003c\/p\u003e\n\u003ch2\u003eUses (Indications)\u003c\/h2\u003e\n\u003cp\u003eAccording to official prescribing information, sodium bicarbonate injection is indicated for \u003cstrong\u003etreatment of metabolic acidosis\u003c\/strong\u003e in various critical settings. For example, it is used in severe acidosis associated with:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRenal failure:\u003c\/strong\u003e When kidneys cannot reabsorb bicarbonate, patients develop acidosis that needs correction.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUncontrolled diabetes (DKA):\u003c\/strong\u003e Ketoacidosis can cause dangerously low pH (though insulin is primary treatment). Bicarbonate may be given if pH is extremely low.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCirculatory shock or severe dehydration:\u003c\/strong\u003e Shock (from bleeding, sepsis, etc.) and dehydration can lead to lactic acidosis. Bicarbonate may be used as a \u003cstrong\u003ebridge\u003c\/strong\u003e while restoring circulation or fluids.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiac arrest:\u003c\/strong\u003e During CPR, severe acidosis (from low perfusion) can occur. Sodium bicarbonate may help neutralize acid during resuscitation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExtracorporeal circulation:\u003c\/strong\u003e Procedures like cardiopulmonary bypass or hemodialysis can disturb acid–base balance; bicarbonate is used to counteract acidosis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIt is also indicated for \u003cstrong\u003ecertain poisonings or toxin exposures\u003c\/strong\u003e where alkalinizing the blood or urine is beneficial. These include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAspirin (salicylate) overdose:\u003c\/strong\u003e Bicarbonate can help ionize the drug and reduce CNS uptake.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBarbiturate poisoning:\u003c\/strong\u003e Raises blood\/urine pH to promote excretion of barbiturates (which are weak acids).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMethanol or ethylene glycol poisoning:\u003c\/strong\u003e Helps slow conversion of toxins to acids and increases excretion.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHemolytic reactions:\u003c\/strong\u003e In patients with massive hemolysis, bicarbonate is given to alkalinize the urine and prevent kidney damage from hemoglobin breakdown products.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFurthermore, sodium bicarbonate injection may be used for \u003cstrong\u003esevere acidosis from other causes\u003c\/strong\u003e (e.g. prolonged seizures, severe diarrhea with bicarbonate loss) where urgent correction of pH is needed. In all cases, treating the underlying cause (e.g. giving insulin for DKA, fluid for shock) must be done in parallel.\u003c\/p\u003e\n\u003ch2\u003eAdministration and Dosage\u003c\/h2\u003e\n\u003cp\u003eThis medication is \u003cstrong\u003egiven intravenously only\u003c\/strong\u003e under medical supervision (usually in a hospital). The dose and rate depend on the patient’s blood pH, plasma CO₂ (bicarbonate) level, and body size. Common principles:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eConcentration and equivalence:\u003c\/strong\u003e 4.2% solution means 4.2 grams per 100 mL. Each mL contains 0.5 mEq of bicarbonate. For reference, a full 50 mL vial of 4.2% contains 2.1 grams (approximately 25 mEq) of bicarbonate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDosing:\u003c\/strong\u003e Often, doctors may give 1–2 ampules (50–100 mL) of 4.2% solution IV as a bolus or over 10–20 minutes, then reassess. Larger, slower infusions may be needed for ongoing therapy. (In emergent cases like cardiac arrest, 1 ampule may be given rapidly, but caution is needed.)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdministration:\u003c\/strong\u003e Only use a \u003cstrong\u003enew sterile syringe\u003c\/strong\u003e and needle. Draw up the required volume (discard any unused portion, as it’s meant for single-dose use). Inject or infuse \u003cstrong\u003eslowly\u003c\/strong\u003e—rapid injection can cause severe hypotension. It is often diluted in IV fluid (e.g. with normal saline or D5W) and infused with a pump. The medical team will monitor blood gases, electrolytes, and vital signs during administration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMonitoring:\u003c\/strong\u003e Expect the patient to have frequent blood gas checks (pH, bicarbonate levels) to see if acidosis is corrected. Doses are often split into 4–6 hour intervals if needed, since infusion shifts the buffer system gradually.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe goal is to raise blood bicarbonate to a safe level (often targeting a pH in the low 7s). \u003cstrong\u003eOvercorrection is dangerous\u003c\/strong\u003e, so it’s given in fractional doses and labs are rechecked. Medical staff will also watch fluid balance, as the solution adds significant sodium and volume.\u003c\/p\u003e\n\u003ch2\u003eSide Effects and Precautions\u003c\/h2\u003e\n\u003cp\u003eBecause sodium bicarbonate injection strongly affects pH and sodium load, it has important risks:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAlkalosis:\u003c\/strong\u003e If too much bicarbonate is given, \u003cstrong\u003emetabolic alkalosis\u003c\/strong\u003e can occur. Symptoms of alkalosis include muscle twitching, irritability, tetany or cramps (from low calcium\/phosphate), and confusion. To avoid this, dosage is guided by blood tests. Bicarbonate therapy is usually reserved for \u003cem\u003esevere\u003c\/em\u003e acidosis, not mild cases.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSodium and fluid overload:\u003c\/strong\u003e Each mL of 4.2% contains 0.5 mEq Na⁺. Large doses can deliver many milliequivalents of sodium, potentially leading to \u003cstrong\u003ehypernatremia\u003c\/strong\u003e or worsened edema. Patients with heart failure, kidney failure, hypertension, or fluid retention must be given this drug cautiously (if at all), because they may not handle the extra salt and water.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInfiltration injury:\u003c\/strong\u003e The solution is highly alkaline and hypertonic. If the IV leaks into the tissue (extravascular infiltration), it can cause \u003cstrong\u003esevere tissue injury\u003c\/strong\u003e. Cases of chemical cellulitis and tissue necrosis have been reported after infiltration of sodium bicarbonate. Medical staff will ensure the IV site is well-placed and will stop infusion immediately if swelling or pain is noted. If infiltration occurs, they recommend elevating the limb and sometimes injecting saline or lidocaine around the site to dilute the bicarbonate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElectrolyte shifts:\u003c\/strong\u003e As blood pH rises, calcium and potassium levels can drop. Severe alkalosis can cause \u003cstrong\u003ehypokalemia\u003c\/strong\u003e (leading to arrhythmias) and \u003cstrong\u003ehypocalcemia\u003c\/strong\u003e (causing muscle cramps or spasms). Potassium and calcium levels should be monitored and replaced as needed when giving this drug. In fact, the labeling warns that potassium depletion can precipitate alkalosis, and hypocalcemia can trigger spasms as pH rises.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVentilation\/CO₂:\u003c\/strong\u003e Although not explicitly stated in the label, it’s clinically important to know that bicarbonate administration generates CO₂ in the body (from HCO₃⁻ + H⁺ → CO₂ + H₂O). If the patient is not ventilating well (e.g. respiratory failure), the additional CO₂ can build up, which may limit the effectiveness of bicarbonate therapy. In practice, patients receiving bicarbonate infusions are often on mechanical ventilation or have good respiratory function, so CO₂ can be blown off.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eContraindications:\u003c\/strong\u003e Do not give sodium bicarbonate if the patient already has metabolic alkalosis or is losing chloride (e.g. vomiting, continuous GI suction), because bicarbonate would worsen their imbalance. Also avoid use if the patient is on certain diuretics (like loop diuretics) that cause hypochloremic alkalosis.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDrug Interactions:\u003c\/strong\u003e Bicarbonate can precipitate calcium-containing solutions, so avoid mixing it with IV solutions that have calcium (like calcium gluconate) unless compatibility is confirmed. It may also interact with some vasoactive drugs; for example, norepinephrine\/dobutamine are incompatible. Always flush the IV line before and after bicarbonate administration.\u003c\/p\u003e\n\u003ch2\u003eKey Points\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurpose:\u003c\/strong\u003e Sodium bicarbonate 4.2% IV is a \u003cstrong\u003estong alkalinizing solution\u003c\/strong\u003e used in hospitals for life-threatening acidosis (e.g. severe renal failure, DKA, shock, cardiac arrest) and certain poisonings. It is \u003cstrong\u003enot\u003c\/strong\u003e a routine medication or oral household remedy.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdministration:\u003c\/strong\u003e Given only by healthcare professionals. It must be diluted and infused or slowly injected IV, with continuous monitoring of blood pH and electrolytes. Rapid or excessive dosing can be harmful.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRisks:\u003c\/strong\u003e Major risks include \u003cstrong\u003eovercorrection to alkalosis\u003c\/strong\u003e, high sodium load (fluid overload, high blood pressure), and tissue injury from extravasation. Beware of alkalosis symptoms (twitching, cramps) and neurological changes. Adequate ventilation is needed to clear the CO₂ produced.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUse Wisely:\u003c\/strong\u003e The underlying cause of acidosis must also be treated (e.g. insulin for DKA, fluids for shock). Bicarbonate is a temporizing measure to raise pH quickly while definitive therapy takes effect.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003cem\u003eDisclaimer: The information is for general knowledge and \u003cstrong\u003enot\u003c\/strong\u003e personal medical advice.\u003c\/em\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"Pfizer Injectables","offers":[{"title":"Default Title","offer_id":51673483477360,"sku":"00409-5555-02","price":399.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Sodium-Bicarbonate-Injection-4.2-Vials-5-ml-hospira.jpg?v=1756310431"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/collections\/Sodium-Bicarbonate-Injection.jpg?v=1739383806","url":"https:\/\/www.mountainside-medical.com\/collections\/sodium-bicarbonate-injections\/exela-pharma-sciences+sodium-bicarbonate+severe-renal-disease.oembed","provider":"Mountainside Medical","version":"1.0","type":"link"}