{"title":"Tubersol Skin Tests","description":"\u003ch1\u003eTB Skin Tests (Mantoux Test)\u003c\/h1\u003e\n\u003cp\u003eA\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003etuberculin skin test (TST)\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e– often called the Mantoux test – is used to detect\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eMycobacterium tuberculosis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003einfection (latent or active) by intradermal injection of tuberculin PPD. In North America, the standard dose is\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003e0.1 mL containing 5 tuberculin units (TU) of PPD\u003c\/strong\u003e. The PPD solution (Aplisol® or Tubersol®) is injected into the \u003cstrong\u003einner forearm\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ewith a 27-gauge needle; a small, pale wheal (6–10 mm) should form if done correctly. A properly done test causes no systemic drug effect – it simply establishes whether the person’s immune system recognises TB antigens.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eAdministration (Mantoux Method):\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eThe patient’s forearm skin is cleaned, and 0.1 mL (5 TU) of PPD is injected intradermally on the volar forearm. The needle bevel is up, and the injection is just under the skin; a visible wheal should appear. If the skin test solution is incorrectly given (wrong volume or too deep), the test is invalid and should be repeated at a new site at least 2″ away. After injection, the patient leaves and returns\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003e48–72 hours later\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003efor reading.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eReading the Test:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eA trained health professional measures the\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003ediameter of induration (firm swelling)\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eat the site – NOT the redness – in millimetres. (If no induration is palpable, record 0 mm.) The reading must be at 48–72 hours; if the patient does not return within 72 hours, the test should be redone (there is no harm in repeating a skin test). Delay beyond 72 hours invalidates the result, as dermal reactions wane.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eInterpreting Results:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eInterpretation depends on the size of induration and the individual’s risk factors. Current CDC cutoffs are:\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003e≥5 mm\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eis positive in high-risk persons (e.g. HIV infection, close contact of infectious TB, organ transplant recipients, other severely immunocompromised);\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003e≥10 mm\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eis positive in moderate-risk groups (recent immigrants from high-TB areas, injection drug users, residents\/workers of high-risk congregate settings like prisons or shelters, certain medical conditions, children \u0026lt;5 years, etc.);\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003e≥15 mm\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eis positive in persons with no known risk factors. Reactivity between these thresholds is considered negative for the corresponding risk group. For example, an induration of 8 mm would be negative for a low-risk adult but positive for someone on immunosuppressive therapy (since it exceeds 5 mm).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eFalse Positives\/Negatives:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eA TB skin test can yield false results.\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eFalse positives\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003emay occur in persons who received\u003cspan\u003e the \u003c\/span\u003e\u003cstrong\u003eBCG vaccine\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eor who have nontuberculous mycobacteria – there is no way to distinguish these from true TB infection by PPD alone. Therefore, CDC advises that BCG-vaccinated individuals with positive TST still be evaluated as if they had not been vaccinated. Periodic skin testing can also “boost” old BCG-induced reactivity, leading to persistent positives. By contrast,\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003efalse negatives\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ecan occur in very recent TB infection (it takes 2–8 weeks post-exposure for conversion) or in immunosuppressed states (e.g. AIDS, certain cancers, steroid use). Young infants (\u0026lt;6 months) may also react poorly. Thus, a negative test does\u003cspan\u003e \u003c\/span\u003e\u003cem\u003enot\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003ecompletely rule out infection in high-risk cases; if suspicion is high (e.g. symptomatic patient), further evaluation (e.g. chest X-ray, sputum tests) is done regardless of TST result.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eTwo-Step Testing:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eIn some settings (e.g. baseline screening of healthcare workers), a two-step approach is used to avoid misinterpreting a “boosted” response as a new conversion. If the first TST is negative, a second test is given 1–3 weeks later. If the second test is positive, this likely reflects a boosted reaction due to remote infection or BCG, and it is counted as a baseline positive (not a new infection). However, if both are negative, the person is considered TB-free (for now). One-step testing is usually done otherwise.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eWho Should Be Tested:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eTB skin testing is indicated for people at increased risk of TB infection or disease (household contacts of TB cases, immigrants, healthcare workers, homeless, prisoners, etc.). It is even recommended for all people with HIV infection due to the high risk. By contrast, testing is\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003enot needed\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003efor people with a documented positive TB test or history of TB disease, since almost all previously infected persons stay TST-positive indefinitely. The only contraindication is a\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eprior severe reaction\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eto PPD (e.g. blistering or necrosis at the site); otherwise,\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eanyone\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003e(infant, pregnant woman, person with HIV) can safely receive a TST. (Pregnancy is not a contraindication.)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eProcedure and Handling:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eThe Mantoux TST requires careful technique: use a new sterile syringe\/needle for each test, inject intradermally with the bevel up, and confirm a wheal forms. PPD solutions must be refrigerated (2–8 °C) and not frozen. (Refer to product info for specifics.) Reading should be done by a trained provider with a ruler perpendicular to the arm’s long axis.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eAdvantages\/Disadvantages:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eThe TST’s advantages are that it is simple, low-cost, and well-studied. However, it has drawbacks: it requires two patient visits (administration and reading), skilled administration and interpretation, and a strict cold-chain for reagents. It can cause booster phenomena on repeated testing and is subject to false positives (BCG, nontuberculous mycobacteria) or false negatives in immunocompromise. Rarely, strong local reactions (pain, swelling, ulceration) or systemic allergic reactions (rash, anaphylaxis) can occur. Epinephrine should be immediately available in the unlikely event of anaphylaxis.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003eAlternatives:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eCDC currently recommends newer\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eTB blood tests (IGRAs)\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eas the preferred method in many cases. IGRAs (e.g. QuantiFERON, T-Spot) require one visit and are not affected by BCG vaccination. However, TST remains acceptable when blood tests aren’t available or feasible, or for children under 5 (where IGRAs are less reliable).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eKey Points:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eThe Mantoux TST uses a standardised PPD intradermal injection (0.1 mL = 5 TU). The site is read 48–72 hours later by measuring induration. The cutoff for a “positive” test varies (≥5, ≥10, or ≥15 mm) depending on the person’s TB risk. Anyone with a concerning reaction (high induration) requires further TB evaluation (chest X-ray, health assessment). BCG vaccination or non-TB mycobacteria exposure do \u003cem\u003enot\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eexclude a positive result – interpret all results by risk categories. If a person has documented TB infection or a previous positive test, repeating a skin test adds no value. For baseline two-step (e.g. health workers), use a second test after 1–3 weeks if the first is negative. Always follow up any positive TST with a medical evaluation for latent or active TB.\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003cem\u003eDisclaimer: This information is for educational purposes only. For personal medical advice (e.g. reading your own test, treatment of TB infection), consult a qualified healthcare provider.\u003c\/em\u003e\u003c\/span\u003e\u003c\/p\u003e","products":[{"product_id":"tubersol-tuberculin-purified-protein-derivative-mantoux-1-ml-10-tests","title":"Tubersol Tuberculin Purified Protein Derivative 1 mL (10 Tests) (Rx) *Refrigerated *","description":"\u003ch1\u003eTubersol Tuberculin Purified Protein Derivative\u003c\/h1\u003e\n\u003cp\u003e\u003cstrong\u003eTubersol\u003c\/strong\u003e by \u003cstrong\u003eSanofi\u003c\/strong\u003e is the gold standard for accurate, reliable, and safe screening of latent and active tuberculosis (TB) infection. This FDA-approved, sterile, Tween-stabilized \u003cstrong\u003eTuberculin Purified Protein Derivative (PPD)\u003c\/strong\u003e solution is preferred by clinics, hospitals, occupational health, and public health facilities for the \u003cstrong\u003eMantoux tuberculin skin test (TST)\u003c\/strong\u003e procedure. With rigorous manufacturing and globally trusted performance, Tubersol simplifies TB screening for healthcare professionals and ensures the best results for patient monitoring and outbreak control.\u003c\/p\u003e\n\u003cp\u003eTubersol Tuberculin Purified Protein Derivative (PPD) (Mantoux) 1 mL (10 Tests) Tween Stabilized Solution is the trusted choice for healthcare professionals worldwide in the detection of latent or active tuberculosis (TB) infection. This highly purified PPD solution is specifically designed for the renowned Mantoux tuberculin skin test (TST). Each vial contains 1 mL of stabilized solution (equal to 10 tests), ensuring consistency, accuracy, and reliability in TB screening programs for hospitals, laboratories, public health agencies, and clinics.\u003cstrong\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eHow Tubersol Works\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eTubersol is administered intradermally via the Mantoux technique. The purified protein derivative (PPD) stimulates a delayed-type hypersensitivity (DTH) immune response in individuals sensitized to Mycobacterium tuberculosis. Read the induration region at the site 48-72 hours post-injection for accurate TB diagnosis.\u003c\/p\u003e\n\u003cp\u003eTubersol Tuberculin Purified Protein Derivative (Mantoux) is used for conducting the Mantoux tuberculin skin test, which helps diagnose latent tuberculosis infection. This solution is administered intradermally to assess the body's immune response to the TB antigen. A critical tool in public health, it aids in identifying individuals who have been exposed to Mycobacterium tuberculosis. The solution is stabilized with Tween, ensuring consistent results for accurate TB screening and management.\u003cstrong\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eInterpretation of Results\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePositive TST:\u003c\/strong\u003e Indicates TB infection (active or latent); follow up with chest x-ray and\/or clinical assessment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNegative TST:\u003c\/strong\u003e Typically rules out TB infection; consider patient history, risk factors, and immunocompromised status.\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eFull Manufacturer’s Instructions Provided\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTubersol Tuberculin Purified Protein Derivative (Mantoux) 1 mL\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003eQuantity: \u003c\/strong\u003e10 Tests per vial\u003cbr\u003e\u003cstrong\u003eFormulation:\u003c\/strong\u003e Tween Stabilized Solution\u003cbr\u003e\u003cstrong\u003eMethod:\u003c\/strong\u003e Mantoux method – intradermal injection\u003cbr\u003e\u003cstrong\u003eIntended Use:\u003c\/strong\u003e Detection of latent tuberculosis infection\u003cbr\u003e\u003cstrong\u003eApplication:\u003c\/strong\u003e Used by healthcare professionals for skin test diagnosis\u003cbr\u003e\u003cstrong\u003eDosage and Administration:\u003c\/strong\u003e Follow healthcare guidelines for dosage and administration for conducting the Mantoux test\u003cbr\u003e\u003cstrong\u003eStorage Conditions:\u003c\/strong\u003e Store refrigerated between 2°C and 8°C (35°F to 46°F); do not freeze\u003cbr\u003e\u003cstrong\u003eStability:\u003c\/strong\u003e Ensure the solution is clear and free from particulate matter before use\u003cbr\u003e\u003cstrong\u003ePrecautions:\u003c\/strong\u003e For professional use only; read the package insert for full instructions and safety information before use\u003c\/p\u003e\n\u003ch2\u003eOrder Tubersol Tuberculin PPD (Mantoux) 1 mL (10 Tests) by Sanofi Today!\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eNDC:\u003c\/strong\u003e 49281-0752-21 | \u003cstrong\u003eUPC:\u003c\/strong\u003e 349281752216 \u003cstrong\u003eFast Shipping | 100% Authentic | Bulk Discounts Available\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEnsure TB safety for your facility, workforce, or patient population with the leading tuberculin PPD test from Sanofi. For the best accuracy, reliability, and clinical value—choose Tubersol for your tuberculosis testing needs.\u003c\/p\u003e","brand":"Sanofi","offers":[{"title":"Default Title","offer_id":12242807357512,"sku":"49281-0752-21","price":249.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Tubersol-Tuberculin-Purified-Protein-Derivative-Mantoux-10-tests-bySanofi-NDC-49281-0752-21.jpg?v=1721934988"},{"product_id":"tubersol-tuberculin-purified-protein-derivative-mantoux-5-ml-50-tests","title":"Tubersol Tuberculin Purified Protein Derivative (Mantoux) 5 mL (50 Tests) *Refrigerated*","description":"\u003cp\u003e\u003cstrong\u003eTubersol Tuberculin Purified Protein Derivative (Mantoux) 5 mL (50 Tests) by Sanofi – The Gold Standard for TB Diagnosis\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 10.5pt;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-family: 'Segoe UI', sans-serif; color: #ff2a00;\"\u003e***Item Requires Refrigeration***\u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003eFast, Reliable Tuberculosis (TB) Testing for Healthcare Professionals\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eTubersol Tuberculin Purified Protein Derivative (Mantoux) 5 mL (50 Tests)\u003c\/strong\u003e by Sanofi is the industry-leading solution for efficient and highly accurate \u003cstrong\u003etuberculosis (TB) screening\u003c\/strong\u003e and \u003cstrong\u003ediagnostic testing\u003c\/strong\u003e. Trusted by \u003cstrong\u003ehospitals, clinics, physicians, public health programs\u003c\/strong\u003e, and occupational health settings worldwide, Tubersol enables fast, sensitive detection of \u003cem\u003eMycobacterium tuberculosis\u003c\/em\u003e infection, including latent tuberculosis infection (LTBI). This Mantoux test is your top choice for meeting CDC TB screening protocols and ensuring \u003cstrong\u003epatient safety\u003c\/strong\u003e.\u003c\/p\u003e\n\u003ch2\u003eProduct Features \u0026amp; Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurified Protein Derivative (PPD):\u003c\/strong\u003e Standardized and FDA-approved for reliable Mantoux tuberculin skin tests.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigh Sensitivity \u0026amp; Specificity:\u003c\/strong\u003e Detects both latent and active TB infection with exceptional accuracy, reducing false positives and negatives.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEasy-to-Use 5 mL Vial:\u003c\/strong\u003e Each vial yields up to 50 tests, perfect for high-volume screening in healthcare settings.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLong Shelf Life:\u003c\/strong\u003e Maintains potency when properly stored, optimizing cost-efficiency and inventory management.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSanofi Quality:\u003c\/strong\u003e Manufactured to the highest pharmaceutical standards for safety and efficacy.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\u003cimg style=\"margin-right: autopx; margin-bottom: 16px; margin-left: autopx; float: none;\" alt=\"Doctor holding Tubersol Tuberculin Purified Protein Derivative (Mantoux) Vial\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Doctor-holding-Tubersol-Tuberculin-Purified-Protein-Derivative-_Mantoux_-Vial_480x480.jpg?v=1758631354\"\u003e\u003c\/div\u003e\n\u003ch2\u003eWhy Use Tubersol for Tuberculosis Testing?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrevent TB Spread:\u003c\/strong\u003e Early detection is critical for TB control and public health.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMandatory for Healthcare Workers:\u003c\/strong\u003e Adheres to CDC, WHO, and OSHA regulations for employee health screening.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAccurate TB Diagnosis:\u003c\/strong\u003e Essential for screening at-risk populations, such as immunocompromised patients, HIV-positive individuals, and recent immigrants.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConsistent Results:\u003c\/strong\u003e Gold standard for TB surveillance, pre-employment exams, and routine physicals.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eDirections for Use\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdminister Intradermally:\u003c\/strong\u003e Following CDC and manufacturer protocols, inject 0.1 mL intradermally on the forearm.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRead 48-72 Hours Later:\u003c\/strong\u003e Measure induration to determine TB infection status.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinical Interpretation:\u003c\/strong\u003e Consult with public health or infectious disease guidelines.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eSpecifications:\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eManufacturer:\u003c\/strong\u003e Sanofi\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVolume:\u003c\/strong\u003e 5 mL vial (50 tests)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Purified Protein Derivative (Mantoux)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUsage:\u003c\/strong\u003e For healthcare professional use only\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eOrder Tubersol Tuberculin Today\u003c\/h2\u003e\n\u003cp\u003eStay compliant, protect your patients and staff, and make \u003cstrong\u003eTubersol Tuberculin Purified Protein Derivative (Mantoux) 5 mL (50 Tests) by Sanofi\u003c\/strong\u003e your first choice for \u003cstrong\u003ereliable, large-scale TB screening\u003c\/strong\u003e. \u003cstrong\u003eOrder now\u003c\/strong\u003e for fast shipping and exceptional customer support.\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003cstrong\u003eBuy Tubersol PPD now and safeguard your healthcare environment with the world’s leading TB testing solution!\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"Sanofi","offers":[{"title":"Default Title","offer_id":12242808078408,"sku":"49281-0752-22","price":639.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Tubersol-Tuberculin-Purified-Protein-Derivative-_Mantoux_-5-mL.jpg?v=1758631156"},{"product_id":"aplisol-tuberculin-purified-protein-derivative-mantoux-1-ml-10-tests","title":"Aplisol Tuberculin Purified Protein Derivative Skin Test Diluted 1 mL (10 Tests) (Rx) * Refrigerated Item *","description":"\u003cp\u003ePar Sterile Products Aplisol Tuberculin Purified Protein Derivative, specifically Diluted 1 mL (10 Tests), is used to perform the Mantoux tuberculin skin test for detecting latent tuberculosis (TB) infections. Administered intradermally, Aplisol triggers an immune response in individuals previously sensitized to Mycobacterium tuberculosis. Health professionals evaluate the injection site 48 to 72 hours later for any induration or swelling, which may indicate TB exposure. This test is crucial for screening vulnerable populations, aiding in early TB detection, monitoring, and potential treatment.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #ff2a00;\"\u003e\u003cstrong\u003e\u003cem\u003e*** Item ships next day air, signature required. ***\u003c\/em\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eAplisol Test is a simple modified complement fixation test used to detect Mycobacterium tuberculosis (MTB) antigens in human body. Aplisol Test (also known as Tuberculin Purified Protein Derivative or PPD) is made up of a solution and MTB germs which can attach to antibodies present in the person's body to form a foam when injected beneath the person's skin. If the person has been in contact with MTB, he\/she produces antibodies against MTB and so the Aplisol Test would check for this and it provides results in two days. In other words, Aplisol Test functions as an immunological reagent and detects antibody\/antigen reactions in people to test whether an individual is infected with or has been exposed to certain disease-causing bacteria. It is a highlyspecifi test which can beochecked for infections like Tuberculosis and so is most widely used Aplisol Test around the world.\u003cspan style=\"color: #ff2a00;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003c\/em\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAplisol Tuberculin Purified Protein Derivative, Diluted\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003eManufacturer:\u003c\/strong\u003e Par Sterile Products LLC\u003cbr\u003e\u003cstrong\u003eVolume:\u003c\/strong\u003e 1 mL per vial (sufficient for 10 skin tests)\u003cbr\u003e\u003cstrong\u003eComposition:\u003c\/strong\u003e Purified protein derivative\u003cbr\u003e\u003cstrong\u003eIntended Use: \u003c\/strong\u003eDiagnostic aid for the detection of latent Mycobacterium tuberculosis infection using the Mantoux technique.\u003cbr\u003e\u003cstrong\u003eApplication Method: \u003c\/strong\u003eIntradermal injection following the Mantoux method\u003cbr\u003e\u003cstrong\u003eTarget Users: \u003c\/strong\u003eHealthcare professionals in medical settings\u003cbr\u003e\u003cstrong\u003eDosage: \u003c\/strong\u003eTypically 0.1 mL is injected intradermally for each test, as per healthcare guidelines\u003cbr\u003e\u003cstrong\u003eStorage Requirements: \u003c\/strong\u003eRefrigerate at 2°C to 8°C (35°F to 46°F); maintain proper cold chain until use\u003cbr\u003e\u003cstrong\u003eSafety Precautions:\u003c\/strong\u003e Strictly for healthcare professional use; consult the package insert for detailed instructions, guidelines, and safety precautions.\u003cbr\u003e\u003cstrong\u003eInspection: \u003c\/strong\u003eEnsure solution clarity and absence of particulates prior to use\u003cbr\u003e\u003cstrong\u003eRegulatory Compliance:\u003c\/strong\u003e Adheres to healthcare and safety standards for TB testing\u003c\/p\u003e\n\u003cp\u003eAplisol is an efficient, trusted choice for healthcare providers committed to excellence in TB testing and control, delivering consistent results to facilitate proactive health management.\u003cbr\u003e\u003c\/p\u003e\n\u003c!-- Microdata markup added by Google Structured Data Markup Helper. --\u003e","brand":"Par Sterile Products LLC","offers":[{"title":"Default Title","offer_id":12242823118920,"sku":"42023-0104-01","price":229.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Tuberculin-Purified-Protein-Derivative-Diluted-Aplisol-1-mL-by-Par-Sterile-NDC-42023-0104-01.jpg?v=1722001522"},{"product_id":"aplisol-tuberculin-purified-protein-derivative-mantoux-5-ml-50-tests","title":"Aplisol Tuberculin TB Test PPD Purified Protein Derivative Mantoux Skin Test 5 TU \/0.1 mL 5 mL (50 Tests) (Rx) Refrigerated","description":"\u003ch1\u003eAplisol Tuberculin TB Skin Test (M\u003cspan class=\"VODHU pdMy8\"\u003eantoux Test)\u003c\/span\u003e\n\u003c\/h1\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003cstrong\u003eAplisol\u003c\/strong\u003e is a sterile intradermal diagnostic antigen used to detect \u003cem\u003eMycobacterium tuberculosis\u003c\/em\u003e infection. It contains \u003cstrong\u003epurified protein derivative (PPD)\u003c\/strong\u003e from \u003cem\u003eM. tuberculosis\u003c\/em\u003e (prepared by the Seibert method) at a standardized potency of \u003cstrong\u003e5 tuberculin units (TU) per 0.1 mL\u003c\/strong\u003e. Aplisol is indicated \u003cstrong\u003eas an aid\u003c\/strong\u003e in diagnosing tuberculosis infection (latent or active). It is not a vaccine or treatment, but a skin test antigen. The solution is ready-to-use (no dilution needed) and contains a phenol preservative\u003c\/span\u003e.\u003c\/p\u003e\n\u003ch2\u003eAplisol Tuberculin PPD Skin Test Features:\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHighest Accuracy for TB Testing:\u003c\/strong\u003e Contains purified protein derivative (PPD) with 5 Tuberculin Units (TU) per 0.1 mL for standard, CDC-recommended Mantoux tuberculin skin testing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFDA Approved \u0026amp; Clinician Trusted:\u003c\/strong\u003e Aplisol is manufactured under strict sterile conditions, ensuring safety and reliability for mass screening and routine testing purposes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBulk 5mL Vial – 50 Doses:\u003c\/strong\u003e Cost-effective, convenient packaging meets high-volume screening needs in healthcare, laboratory, and workplace environments.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSterile, Non-Pyrogenic Solution:\u003c\/strong\u003e Reduces risk of patient reactions and provides consistent testing results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRapid, Easy Administration:\u003c\/strong\u003e Administers easily with a single intradermal injection; results can be evaluated within 48 – 72 hours for fast, actionable TB detection.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBroad Applications:\u003c\/strong\u003e Essential for entry\/annual screening of healthcare workers, students, correctional facilities, immigrants, and close contacts of TB patients.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eAdministration (Mantoux Method)\u003c\/h2\u003e\n\u003cp\u003eThe standard Mantoux technique is used with Aplisol. A trained healthcare provider performs the test as follows.\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eInject 0.1 mL intradermally (5 TU):\u003c\/strong\u003e Using a 27-gauge needle, inject 0.1 mL of Aplisol into the \u003cstrong\u003evolar (inner) surface of the forearm\u003c\/strong\u003e, about 4″ below the elbow. A small pale wheal (6–10 mm) should appear if done correctly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReading the site (48–72 hours):\u003c\/strong\u003e The injection site is examined \u003cstrong\u003e48 to 72 hours\u003c\/strong\u003e later by a trained reader. Measure only the diameter of \u003cstrong\u003einduration\u003c\/strong\u003e (the firm, raised area) in millimeters; do \u003cstrong\u003enot\u003c\/strong\u003e measure redness (erythema). If no induration is palpable, record “0 mm.” If only erythema (redness) is present without induration, the test is considered negative (often indicating too-deep injection). If an improper dose was given or the test invalid (no wheal), the test should be repeated at a new site..\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cstrong\u003eAdministration tips:\u003c\/strong\u003e Use a new sterile syringe\/needle per patient and clean the site with alcohol before injection. Ensure the full 0.1 mL (5 TU) is delivered intradermally; more than 30 minutes elapsing before testing can reduce potency. Pregnancy is \u003cstrong\u003enot\u003c\/strong\u003e a contraindication; tuberculin testing is considered safe and valid during pregnancy.\u003c\/p\u003e\n\u003ch2\u003eInterpreting Results\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePositive reaction:\u003c\/strong\u003e An induration \u003cstrong\u003e≥5 mm\u003c\/strong\u003e is considered positive in \u003cem\u003ehigh-risk\u003c\/em\u003e individuals (e.g. HIV-positive, recent TB contacts, immunosuppressed). An induration \u003cstrong\u003e≥10 mm\u003c\/strong\u003e is positive in people with moderate risk (e.g. immigrants from high-TB countries, injection drug users, certain medical conditions, children \u0026lt;5). An induration \u003cstrong\u003e≥15 mm\u003c\/strong\u003e is positive in people with \u003cem\u003eno\u003c\/em\u003e known risk factors. (These cutoffs follow current CDC guidelines.)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNegative reaction:\u003c\/strong\u003e An induration \u003cstrong\u003e\u0026lt;5 mm\u003c\/strong\u003e is typically negative in low-risk people. However, false negatives can occur in immunocompromised persons or very recent infections (it takes 2–8 weeks post-infection for a positive PPD to develop).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eEach result must be interpreted in context. For example, a \u003cem\u003eBCG-vaccinated\u003c\/em\u003e person with a positive reaction should be evaluated as if \u003cem\u003enot\u003c\/em\u003e vaccinated (since BCG effects wane over time). Likewise, repeat “two-step” testing (two PPD tests 1–3 weeks apart) may be used in periodic screening to distinguish a boosted reaction from a new infection.\u003c\/p\u003e\n\u003ch2\u003eSide Effects and Reactions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eLocal reactions\u003c\/strong\u003e are common: pain, redness, swelling at injection site. A strongly positive test can cause blistering, ulceration, or necrosis at the site, sometimes leading to a scar. These are not infections but inflammatory responses. Apply cold packs or topical steroids for comfort if needed.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSystemic allergic reactions\u003c\/strong\u003e are very rare but possible: rash, urticaria, angioedema, and even anaphylaxis have been reported. If any sign of severe allergy occurs, seek medical help immediately. Note: because of the preservative phenol, some people may have mild sensitivity.\u003c\/p\u003e\n\u003ch2\u003eProduct Specifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBrand:\u003c\/strong\u003e Aplisol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eManufacturer:\u003c\/strong\u003e Par Sterile Products LLC\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eType:\u003c\/strong\u003e Tuberculin PPD Purified Protein Derivative\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConcentration:\u003c\/strong\u003e 5 TU \/ 0.1 mL (standard Mantoux test)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVial Size:\u003c\/strong\u003e 5 mL multi-dose vial (approx. 50 tests\/vial)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSterility:\u003c\/strong\u003e Sterile, non-pyrogenic\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdministration:\u003c\/strong\u003e Intradermal injection (usually forearm site)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIndications:\u003c\/strong\u003e TB screening, latent tuberculosis infection (LTBI) detection, annual health and occupational screenings\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Refrigerated (2-8°C)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eBest Uses \u0026amp; Clinical Applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePublic Health \u0026amp; School TB Screening:\u003c\/strong\u003e Rapid, accurate TB detection for students, teachers, and staff members.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOccupational Health \u0026amp; Hospital Employee Testing:\u003c\/strong\u003e Ensure compliance and protect staff with CDC-recommended annual screening.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCommunity Clinics \u0026amp; Prisons:\u003c\/strong\u003e Screen high-risk populations for latent and active tuberculosis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmigration \u0026amp; Visa Health Examinations:\u003c\/strong\u003e Essential for regulatory compliance in immigration processes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClose Contact Risk Assessment:\u003c\/strong\u003e Quickly assess TB exposure and infection among known contacts of TB-positive patients.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eCDC-recommended concentration for maximum test sensitivity\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eBulk 50-dose vial for efficient high-volume testing\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eReduces risk of false positives and patient reactions\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eEnsures safe, sterile intradermal administration\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eSupports public health, compliance, and occupational safety standards\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eTop Medical \u0026amp; Health Search Terms\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAplisol Tuberculin PPD\u003c\/li\u003e\n\u003cli\u003etuberculin skin test\u003c\/li\u003e\n\u003cli\u003ePPD skin test solution\u003c\/li\u003e\n\u003cli\u003eMantoux TB skin test\u003c\/li\u003e\n\u003cli\u003eTB screening test\u003c\/li\u003e\n\u003cli\u003epurified protein derivative test\u003c\/li\u003e\n\u003cli\u003e5 TU tuberculin test\u003c\/li\u003e\n\u003cli\u003eFDA approved TB skin test\u003c\/li\u003e\n\u003cli\u003elatent tuberculosis infection testing\u003c\/li\u003e\n\u003cli\u003eTB test for healthcare workers\u003c\/li\u003e\n\u003cli\u003eworkplace TB screening\u003c\/li\u003e\n\u003cli\u003eTB test for schools and public health\u003c\/li\u003e\n\u003cli\u003emulti-dose vial tuberculin\u003c\/li\u003e\n\u003cli\u003eintradermal TB test\u003c\/li\u003e\n\u003cli\u003etuberculosis PPD injection\u003c\/li\u003e\n\u003cli\u003eoccupational health TB testing\u003c\/li\u003e\n\u003cli\u003eannual TB skin test\u003c\/li\u003e\n\u003cli\u003ePPD 5 TU 0.1 mL\u003c\/li\u003e\n\u003cli\u003ePar Sterile Products Aplisol\u003c\/li\u003e\n\u003cli\u003eaccurate tuberculosis screening kit\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBrand: Par Sterile Products LLC\u003cbr\u003eNDC: 42023-0104-05\u003cbr\u003eUPC: 342023104052\u003cbr\u003eType: Multiple Dose Vial\u003c\/p\u003e\n\u003cp\u003eAplisol PPD (5 TU) is a tuberculosis skin test antigen given intradermally. A 0.1 mL injection yields 5 TU, the standard test dose. After injection, induration is measured at 48–72 hours. The size of induration (not redness) determines the likelihood of TB infection, with risk-based cutoffs (e.g. ≥5 mm in high-risk persons, ≥10 mm in moderate risk, ≥15 mm otherwise). Use caution in those with prior severe reactions (do not test again), and remember that BCG vaccination or non-tuberculous mycobacteria can affect results. Store Aplisol refrigerated (2–8 °C), discard vials after 30 days of use, and always have trained personnel administer and read the test.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eDisclaimer: This information is for educational purposes only. For personal medical advice (e.g. reading your own test, treatment of TB infection), consult a qualified healthcare provider.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003e\u003cstrong\u003eBuy Aplisol Tuberculin PPD Skin Test today for the #1 FDA-approved, physician-trusted TB screening solution and keep your facility compliant and protected!\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"Par Sterile Products LLC","offers":[{"title":"Default Title","offer_id":12242823839816,"sku":"42023-0104-05","price":599.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Tuberculin-Purified-Protein-Derivative-Diluted-Aplisol-by-Par-Sterile-NDC-42023-0104-05.jpg?v=1721933964"},{"product_id":"streptomycin-sulfate-powder-vial-1-ml-x-10-box-rx","title":"Streptomycin Sulfate Antibiotic Medication in Powder Vial 1 mL x 10\/Box (RX)","description":"\u003cp\u003eStreptomycin sulfate injection is an antibiotic medication used to treat infections caused by bacteria, such as tuberculosis and certain types of pneumonia. It is also used to prevent infections in surgical procedures and in cases of whooping cough.\u003c\/p\u003e\n\u003cp\u003eStreptomycin sulfate powdered vial 1 ml is a form of the antibiotic streptomycin sulfate that is packaged in a vial with one milliliter (ml) volume of powder. This vial may be used for reconstitution in order to create a solution for use in medical treatments, lab experiments, or other purposes. Streptomycin sulfate is effective against a variety of bacteria and is commonly used to treat infections such as tuberculosis and certain types of pneumonia. The powdered form of this medication allows for easy storage and transportation while maintaining its potency.\u003c\/p\u003e\n\u003cp\u003eStreptomycin sulfate injection works by interfering with the growth and reproduction of bacteria. It belongs to the class of antibiotics known as aminoglycosides. It works by binding to the bacterial ribosomes, which are responsible for protein synthesis. This binding disrupts the production of essential proteins and ultimately leads to the death of the bacteria. Streptomycin sulfate is effective against a wide range of bacteria, including those that cause tuberculosis, plague, and bacterial meningitis.\u003c\/p\u003e","brand":"Xgen Pharma","offers":[{"title":"Default Title","offer_id":40238402797640,"sku":"39822-0706-02","price":760.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Streptomycin-Sulfate-Antibiotic-Medication-in-Powder-Vial-1-mL.jpg?v=1714135863"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/collections\/Tuberculin_Tests.jpg?v=1775738000","url":"https:\/\/www.mountainside-medical.com\/collections\/tubersol.oembed?constraint=tuberculosis-diagnosis","provider":"Mountainside Medical","version":"1.0","type":"link"}