{"product_id":"lidocaine-2-with-epinephrine-1-100-000-1-7-ml-50-box","title":"Lidocaine 2% with Epinephrine 1:100,000 1.7 mL Cartridge 50\/Box (RX)","description":"\u003ch1\u003eLidocaine 2% with Epinephrine 1:100,000 (1.7 mL cartridge)\u003c\/h1\u003e\n\u003cp\u003e\u003cspan class=\"VODHU pdMy8\"\u003eLidocaine 2% with epinephrine 1:100,000 is a common local anesthetic injection used in dentistry. It is sold as 1.7 mL cartridges (often red-coded) by dental suppliers like Henry Schein. Lidocaine HCl is an \u003cstrong\u003eamide-type local anesthetic\u003c\/strong\u003e (it numbs nerve tissue).. Epinephrine (adrenaline) is included as a \u003cstrong\u003evasoconstrictor\u003c\/strong\u003e  – it constricts blood vessels at the injection site, slowing absorption of lidocaine. This reduces bleeding and nearly doubles the anesthetic duration, which is why low-dose epinephrine (1:100,000) is routinely added to dental lidocaine.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003eComposition and Dosage\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e2% Lidocaine:\u003c\/strong\u003e 2% means 2 g per 100 mL, i.e. 20 mg per mL. Thus a 1.7 mL cartridge contains about \u003cstrong\u003e34 mg of lidocaine\u003c\/strong\u003e (1.7 mL × 20 mg\/mL).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEpinephrine 1:100,000:\u003c\/strong\u003e This ratio means 0.01 mg of epinephrine per mL (10 μg\/mL). A 1.7 mL cartridge therefore delivers about \u003cstrong\u003e17 μg of epinephrine\u003c\/strong\u003e (1.7 mL × 10 μg\/mL).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSummary (per cartridge):\u003c\/strong\u003e ~34 mg lidocaine + 0.017 mg epinephrine. (For comparison, 1:50,000 epi cartridges contain 20 μg\/mL epi, so this 1:100,000 formulation has a lower vasoconstrictor dose.)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eMechanism of Action and Use\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eLidocaine (Local Anesthetic):\u003c\/strong\u003e Lidocaine rapidly blocks voltage-gated sodium channels in nerve fibers, preventing pain signals. It “numbs” the target tissue in dentistry by stopping nerve conduction. Onset is quick (a few minutes) with an intermediate duration. 2% lidocaine is one of the most widely used dental anesthetics.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEpinephrine (Vasoconstrictor):\u003c\/strong\u003e Epinephrine constricts blood vessels. By adding epinephrine, absorption of lidocaine is slowed, which prolongs the anesthesia and reduces bleeding. In practice, lidocaine with 1:100,000 epi can have an anesthetic duration nearly twice that of plain lidocaine.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinical Use:\u003c\/strong\u003e This formulation is commonly used for dental local anesthesia (infiltration or nerve block). A typical dose may be one or a few cartridges, depending on the procedure and patient. Onset is within minutes and numbness lasts on the order of 1–3 hours (depending on dose and site).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003ePackaging and Supplier\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCartridge Format:\u003c\/strong\u003e The drug is provided in glass cartridges, 1.7 mL each. Henry Schein (HSI brand) lists these as “Lidocaine HCl 2% Epinephrine 1:100,000 1.7 mL 50\/Bx”. (Dentists will recognize the red color coding for 2% lidocaine with 1:100k epi.)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRegulatory:\u003c\/strong\u003e This is a prescription product (used by licensed practitioners) and is non-returnable. It should be used under appropriate clinical supervision.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Henry Schein","offers":[{"title":"Default Title","offer_id":53868562284912,"sku":"INS4651205","price":78.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Lidocaine-2--with-Epinephrine-Vials-Henry-Schein.jpg?v=1780596574","url":"https:\/\/www.mountainside-medical.com\/products\/lidocaine-2-with-epinephrine-1-100-000-1-7-ml-50-box","provider":"Mountainside Medical","version":"1.0","type":"link"}