{"product_id":"sm-c-acellular-secretome-material-injection-regenerative-medicine","title":"SM-C Acellular Secretome Material Injection, Regenerative medicine","description":"\u003cp\u003eSM-C is a laboratory-characterized acellular secretome material prepared through controlled processing methods and documented through batch-specific analytical reporting.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAcellular secretome\u003c\/strong\u003e refers to the collection of bioactive molecules that are secreted by cells into their surrounding environment, but \u003cstrong\u003ewithout the cells themselves being present\u003c\/strong\u003e (\"acellular\" = \"without cells\"). The secretome is typically collected from the conditioned medium in which cells have been cultured.\u003c\/p\u003e\n\u003ch3\u003eWhat is included in the Acellular Secretome?\u003c\/h3\u003e\n\u003cp\u003eThe acellular secretome is rich in:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eGrowth factors\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eCytokines\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eChemokines\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eExtracellular vesicles (such as exosomes and microvesicles)\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eEnzymes\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eLipids\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eProteins\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eNucleic acids (like mRNA and miRNA)\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eMajor Sources\u003c\/h3\u003e\n\u003cp\u003eThe acellular secretome is often derived from \u003cstrong\u003emesenchymal stem\/stromal cells (MSCs)\u003c\/strong\u003e, but it can come from other types of cells as well (immune cells, tumor cells, etc.).\u003c\/p\u003e\n\u003ch2\u003eUses of Acellular Secretome\u003c\/h2\u003e\n\u003ch3\u003e1. \u003cstrong\u003eRegenerative Medicine\u003c\/strong\u003e\n\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eWound Healing:\u003c\/strong\u003e Promotes tissue repair and skin regeneration for chronic wounds, burns, ulcers, and surgical incisions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBone \u0026amp; Cartilage Repair:\u003c\/strong\u003e Used to aid the regeneration of bone tissue (osteogenesis) and cartilage (chondrogenesis), especially for fractures and osteoarthritis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiac Repair:\u003c\/strong\u003e Improves heart tissue healing after a myocardial infarction (\"heart attack\") by promoting angiogenesis and reducing inflammation and scar tissue.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNerve Repair:\u003c\/strong\u003e Supports regeneration in nerve injury, including peripheral nerve damage and some central nervous system conditions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e2. \u003cstrong\u003eAnti-inflammatory Therapies\u003c\/strong\u003e\n\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eReduces inflammation and modulates immune responses, making it helpful in treating autoimmune diseases and inflammatory conditions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e3. \u003cstrong\u003eAnti-fibrotic Effects\u003c\/strong\u003e\n\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eMay prevent excessive scar tissue formation (fibrosis) in organs like the liver, lung, heart, and kidney.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e4. \u003cstrong\u003eCosmetic and Dermatology Applications\u003c\/strong\u003e\n\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkin Rejuvenation:\u003c\/strong\u003e Used in creams or serums for anti-aging effects, promoting collagen production, and improving skin texture and tone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHair Regrowth:\u003c\/strong\u003e Some products use secretomes for treating hair loss (alopecia) by stimulating hair follicle cells.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e5. \u003cstrong\u003eDiagnostics and Biomarker Discovery\u003c\/strong\u003e\n\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eAnalysis of the secretome’s composition can help detect disease-specific biomarkers, potentially enabling early diagnosis of certain diseases.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e6. \u003cstrong\u003eAnti-Cancer Research\u003c\/strong\u003e\n\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eStudied for both \u003cem\u003esupporting\u003c\/em\u003e anti-tumor immune responses and understanding how tumor cells modulate their environment via their secretome.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e7. \u003cstrong\u003eDrug Delivery and Novel Drug Development\u003c\/strong\u003e\n\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eExtracellular vesicles and exosomes within the secretome can be used as carriers for drug delivery.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch3\u003eBenefits over Cell-based Therapies\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003eLower risk of immune rejection\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eReduced risk of tumorigenesis\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eEasier storage and delivery\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eNo issues related to cell viability or ethical concerns of live cell use\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAcellular secretome\u003c\/strong\u003e is the collection of active factors secreted by cells, harvested from cell cultures, and used for therapeutic or research purposes \u003cstrong\u003ewithout any live cells present\u003c\/strong\u003e.\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eProduct Specifications\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 16px;\"\u003e\u003cstrong\u003eSKU: \u003c\/strong\u003eSM-C-2ML\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 16px;\"\u003e\u003cstrong\u003eMaterial Type: \u003c\/strong\u003eAcellular secretome material\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 16px;\"\u003e\u003cstrong\u003eFormat: \u003c\/strong\u003eSterile liquid preparation\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 16px;\"\u003e\u003cstrong\u003eVolume: \u003c\/strong\u003e2 mL\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 16px;\"\u003e\u003cstrong\u003ePrimary Material Components:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"oe-nested\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 16px;\"\u003e Secreted extracellular biomolecular fractions that may include:\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 16px;\"\u003e Extracellular vesicle populations \u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 16px;\"\u003e Nanoparticle-associated biomolecules \u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 16px;\"\u003e Soluble extracellular proteins and signaling factors \u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 16px;\"\u003e\u003cstrong\u003eShelf Life: \u003c\/strong\u003eUp to 24 months when stored under recommended conditions\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 16px;\"\u003e\u003cstrong\u003eShipping: \u003c\/strong\u003eTemperature-controlled shipment\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003eScientific Characterization\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 16px;\"\u003eSM-C is supplied as a laboratory-characterized acellular secretome material.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 16px;\"\u003eLaboratory documentation may include:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 16px;\"\u003e Analytical characterization of extracellular vesicle and nanoparticle populations \u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 16px;\"\u003e Batch identification and traceability records \u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 16px;\"\u003e Laboratory-generated analytical measurements describing material composition \u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 16px;\"\u003eEach lot may include \u003cstrong\u003eCertificates of Analysis (COAs)\u003c\/strong\u003e and supporting laboratory documentation describing analytical findings.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 16px;\"\u003eAll specifications are provided for \u003cstrong\u003ematerial identification, analytical reference, and documentation purposes only.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eDocumentation\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 16px;\"\u003eSupporting documentation may include:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 16px;\"\u003e Lot-specific \u003cstrong\u003eCertificates of Analysis (COAs)\u003c\/strong\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 16px;\"\u003e Laboratory analytical reports \u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 16px;\"\u003e Batch identification and traceability documentation \u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 16px;\"\u003eThese materials provide transparency regarding the analytical characteristics associated with each production lot.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eStorage \u0026amp; Handling\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 16px;\"\u003eTo maintain material stability, the following storage conditions are recommended:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 16px;\"\u003e\u003cstrong\u003eShort-Term Storage:\u003c\/strong\u003e −20 °C (freezer storage)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 16px;\"\u003e\u003cstrong\u003eLong-Term Storage:\u003c\/strong\u003e Maintain continuous frozen storage conditions\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 16px;\"\u003eAvoid repeated freeze-thaw cycles and maintain appropriate cold-chain handling during transport and storage.\u003c\/span\u003e\u003c\/p\u003e","brand":"Skydell Medical","offers":[{"title":"Default Title","offer_id":54252671107440,"sku":"SM-C","price":150.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/SM-C-Acellular-Secretome-Material-Injection-Regenerative-medicine.jpg?v=1788270204","url":"https:\/\/www.mountainside-medical.com\/products\/sm-c-acellular-secretome-material-injection-regenerative-medicine","provider":"Mountainside Medical","version":"1.0","type":"link"}