{"product_id":"sodium-acetate-injection-2-meq-ml-single-dose-50-ml","title":"Sodium Acetate Injection 2 mEq\/mL Single Dose IV Solution 50 mL (RX)","description":"\u003ch1\u003eHikma Sodium Acetate Injection\u003c\/h1\u003e\n\u003cp\u003e\u003cstrong\u003eUltra-Pure Electrolyte Replenisher for IV Therapy:\u003c\/strong\u003e Hikma’s Sodium Acetate Injection is a \u003cstrong\u003esterile, nonpyrogenic sterile IV solution\u003c\/strong\u003e containing sodium acetate at 2 mEq\/mL (pharmacy bulk 50 mL vial). This clear, colorless liquid is an \u003cstrong\u003einjectable electrolyte infusion\u003c\/strong\u003e, used by hospitals and critical care units to maintain fluid and electrolyte balance. It provides a concentrated source of sodium ions for intravenous fluid therapy and acts as an \u003cstrong\u003ealkalinizing agent\u003c\/strong\u003e (converted metabolically to bicarbonate) to help correct acidosis. Branded by Hikma (a top generic injectable manufacturer), this Sodium Acetate Injection meets FDA and USP standards, offering a reliable ana alternative to sodium chloride in IV hydration and infusion therapy.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eElectrolyte Replacement:\u003c\/strong\u003e Delivers 2 mEq of sodium and 2 mEq of acetate per mL (164 mg sodium acetate anhydrous). The acetate is metabolized to bicarbonate in the body, helping buffer bloodstream pH. Ideal for establishing proper \u003cstrong\u003esodium levels\u003c\/strong\u003e in patients on IV fluids.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBroad Medical Use:\u003c\/strong\u003e Commonly used to \u003cstrong\u003etreat hyponatremia\u003c\/strong\u003e (low blood sodium) in hospitalized patients with restricted\/no oral intake. Also added to Total Parenteral Nutrition (TPN) and large-volume maintenance IV infusions to tailor electrolyte solutions when standard formulas (normal saline, lactated Ringer’s) are insufficient). In \u003cstrong\u003ecritical care\u003c\/strong\u003e, it helps prevent electrolyte imbalances, supports nerve and muscle function, and maintains hydration in ICU and emergency settings.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAcid-Base Support:\u003c\/strong\u003e Acts as a precursor to bicarbonate, making it useful in addressing metabolic acidosis (e.g. lactic acidosis). By raising blood bicarbonate levels, it stabilizes \u003cstrong\u003eacid-base balance\u003c\/strong\u003e in patients with severe metabolic disturbances. This makes it a valuable additive in dialysis, critical care, and anesthesia protocols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePharmacy Bulk Package:\u003c\/strong\u003e Comes as a single 50 mL glass vial intended for pharmacy admixture (liters of IV fluids). \u003cem\u003eNot for direct IV injection\u003c\/em\u003e – must be diluted into compatible IV fluids (e.g. D5W, NS, multivitamin solutions) before patient infusion. The integrated label hanger allows secure laminar flow hood use. Aseptic transfer devices should be used to withdraw doses; discard remaining solution (use within 24 hours).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTrusted Quality:\u003c\/strong\u003e Manufactured by Hikma Injectables (NDC 00641-6262-01). Each vial is USP-grade and preservative-free. Contains no added buffers or antimicrobial agents. Store at controlled room temperature (20–25°C). This CGT-approved product is vital hospital inventory for IV hydration and \u003cstrong\u003eelectrolyte replenishment therapy\u003c\/strong\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eUses \u0026amp; Applications\u003c\/h2\u003e\n\u003cp\u003eSodium Acetate Injection is a versatile \u003cstrong\u003eintravenous hydration and electrolyte solution\u003c\/strong\u003e. Key applications include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHyponatremia Correction:\u003c\/strong\u003e Prevents or corrects low sodium levels during IV therapy in patients unable to eat\/drink (e.g. postoperative, ICU patients).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIV Fluid Additive:\u003c\/strong\u003e Customized compounding of IV fluids. Often added to large-volume maintenance fluids (saline, dextrose solutions) to achieve precise electrolyte composition for individual patient needs. Standard infusion sets and pumps are used after dilution.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolic Acidosis Management:\u003c\/strong\u003e Provides bicarbonate-equivalent via acetate metabolism, supporting correction of metabolic acidosis (e.g. during dialysis or critical illness). Acts similarly to IV sodium bicarbonate in acid-base therapy but can be easier to store\/handle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCritical Care \u0026amp; Surgical Settings:\u003c\/strong\u003e Essential in emergency rooms, ICU, and operating theaters for managing fluid\/electrolyte imbalances. An important component of Total Parenteral Nutrition (TPN) admixtures, neonatal ICU fluids, and shock resuscitation protocols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElectrolyte Maintenance:\u003c\/strong\u003e Helps patients maintain proper osmotic balance and cell function. By replenishing sodium, it indirectly aids in maintaining normal potassium and calcium levels (electrolyte balance). Can prevent dilutional electrolyte disturbances when large IV fluid volumes are given.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eActive Ingredient:\u003c\/strong\u003e Sodium Acetate Anhydrous, 164 mg\/mL (providing 2 mEq Na\u0026lt;sup\u0026gt;+\u0026lt;\/sup\u0026gt; and 2 mEq acetate\/mL).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConcentration:\u003c\/strong\u003e 2 mEq (2 mmol) sodium per mL – equivalent to about 9 mEq in 5 mL, 20 mEq in 10 mL, 100 mEq in 50 mL. (Total ~8,200 mg sodium acetate in 50 mL).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAppearance:\u003c\/strong\u003e Clear, colorless, sterile solution in a glass vial. No preservatives or added buffers. pH 6.5 (range 6.0–7.0); osmolarity ~4 mOsmol\/mL\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVolume:\u003c\/strong\u003e 50 mL single-dose vial (pharmacy bulk container). (Single unit per carton).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNDC:\u003c\/strong\u003e 00641-6262-01 (Hikma Pharmaceuticals, USA). Cosmetic glass ampoule-type vial with aluminum flip-cap and rubber stopper.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoute:\u003c\/strong\u003e Intravenous infusion only (IV). \u003cstrong\u003eStorage:\u003c\/strong\u003e Store at 20–25°C (do not refrigerate). Protect from freezing and light.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePackaging:\u003c\/strong\u003e Supplied Rx-only. Once opened, use aseptic technique to withdraw required amount; discard unused portion within 24 hours.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eHow to Use\u003c\/h2\u003e\n\u003cp\u003eSodium Acetate Injection must be \u003cstrong\u003ediluted\u003c\/strong\u003e before use. Follow these steps for safe administration:\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eCheck Vial Integrity:\u003c\/strong\u003e Ensure the solution is clear and container seal intact. Do not use if cloudy or contaminated. Use only as directed by a pharmacist or doctor.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDilution:\u003c\/strong\u003e Withdraw the prescribed volume into a syringe (using sterile technique) and add it to a compatible IV fluid bag (e.g. 250–1000 mL of NS, D5W, or TPN solution). This yields a hypertonic solution that can be infused slowly. Never inject directly; always prepare an infusion admixture.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdministration:\u003c\/strong\u003e Infuse the diluted solution intravenously using an IV pump or gravity flow. Typical infusion rates depend on clinical protocols and patient condition. Rapid infusion is dangerous—\u003cstrong\u003eadminister slowly\u003c\/strong\u003e to avoid rapid sodium changes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMonitoring:\u003c\/strong\u003e Continuously monitor patient's vital signs and serum electrolytes (especially sodium) during infusion. Adjust the infusion rate or stop the infusion if sodium levels rise too quickly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSingle-Use:\u003c\/strong\u003e This product is single-dose; do not reuse punctured vials. Discard any leftover solution after 24 hours.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cstrong\u003eNote:\u003c\/strong\u003e The standard dilution environment is a laminar-flow hood in the pharmacy. Use a sterile dispensing pin\/syringe instead of needles to minimize contamination risk . Admixtures prepared should be refrigerated and used within the recommended time frame.\u003c\/p\u003e\n\u003ch2\u003eDosage \u0026amp; Administration\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIndividualized Dosing:\u003c\/strong\u003e Sodium acetate dose is tailored to patient needs. Always consult a physician or pharmacist for exact dosing. Generally, the total daily sodium requirement (sodium from all sources) is about 1–2 mEq\/kg body weight. Sodium Acetate provides 2 mEq per mL, so doses often range from a few mEq to the maximum of a couple hundred mEq per day, depending on the severity of hyponatremia or TPN formulation needs. Example: a 70 kg adult might need 70–140 mEq daily.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInfusion Rates:\u003c\/strong\u003e Infuse slowly—rapid sodium correction can be dangerous. For routine electrolyte maintenance, the infusion may run over 8–24 hours. In acute hyponatremia, even then correct no more than ~8-12 mEq\/L per 24 hours. Always follow institutional protocols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdjustment:\u003c\/strong\u003e Adjust infusion based on regular lab tests. Monitor serum sodium, potassium, chloride, and blood gases. Stop infusion if patient develops signs of fluid overload or hypernatremia (confusion, edema, hypertension).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDilution Guidelines:\u003c\/strong\u003e If diluted in 0.9% NaCl or D5W, be aware of resulting osmolarity. Higher concentrations may require central line infusion. Always refer to pharmacopeia or institutional charts for the final IVBag osmolarity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpecial Populations:\u003c\/strong\u003e Use caution in renal impairment, heart failure, or cirrhosis—dose may need to be lower to prevent fluid\/sodium retention. Pediatric and neonatal dosing is weight-based (usually 1–2 mEq\/kg\/day sodium), with careful monitoring.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eDrug Interactions\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNo Direct Drug Interactions:\u003c\/strong\u003e Sodium acetate itself has no known pharmacokinetic interactions (it’s a simple electrolyte). However, because it affects sodium and fluid balance, it can interact indirectly with many medications.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConcurrent Medications:\u003c\/strong\u003e Inform healthcare provider if patient is on diuretics (e.g., furosemide, hydrochlorothiazide) or drugs affecting sodium balance (e.g., ACE inhibitors, ARBs, steroids). These medications can magnify changes in blood sodium or fluid status.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElectrolyte Interactions:\u003c\/strong\u003e Be cautious with other IV electrolytes: combining with \u003cstrong\u003esodium bicarbonate\u003c\/strong\u003e or large-volume saline may elevate serum sodium excessively. Check potassium supplements – correcting hyponatremia with sodium acetate can unmask or worsen hypokalemia.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGeneral Advice:\u003c\/strong\u003e Always coordinate electrolyte infusions with the treating physician and pharmacy. Ask about all prescription meds, over-the-counter vitamins (especially high-sodium antacids or supplements) to avoid unintentional sodium overload.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSide Effects \u0026amp; Warnings\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eCommon\/Reversible:\u003c\/strong\u003e When properly diluted and dosed, side effects are uncommon. Potential effects mostly stem from too much sodium or fluid:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFluid Overload:\u003c\/strong\u003e Signs include swelling (edema), weight gain, high blood pressure, or difficulty breathing. Pulmonary edema (fluid in lungs) can occur if infusion is too fast or in heart\/renal failure patients.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElectrolyte Imbalance:\u003c\/strong\u003e Can cause hypernatremia (excess sodium), hypokalemia (low potassium), hypocalcemia (low calcium), and metabolic alkalosis (high blood pH) if not monitored. Dilution of blood can also alter other laboratory values.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInjection Site:\u003c\/strong\u003e If accidentally given undiluted or in small volume, may cause vein irritation or thrombophlebitis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllergic Reactions:\u003c\/strong\u003e Rare but serious. Stop the infusion immediately if rash, itching, hives, swelling of face\/lips, wheezing, or difficulty breathing occur.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSerious Warnings:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypernatremia and Fluid Retention:\u003c\/strong\u003e Contraindicated in patients already high in sodium or with fluid overload (e.g., heart failure, severe kidney disease). Excessive sodium can worsen high blood pressure or cause dangerous fluid shifts (cerebral edema in rapid correction, congestive states).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHeart\/Kidney\/Liver Disease:\u003c\/strong\u003e Use \u003cem\u003eextreme caution\u003c\/em\u003e if patient has congestive heart failure, hypertension, cirrhosis, or renal insufficiency. These patients can’t excrete sodium as well; even small infusions may cause edema or high serum sodium.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAcid-Base Disorders:\u003c\/strong\u003e Sodium acetate adds base (via acetate). Overuse can lead to \u003cstrong\u003emetabolic alkalosis\u003c\/strong\u003e. Patients with respiratory or metabolic alkalosis should receive this drug only under strict supervision.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInfant\/Neonate Risks:\u003c\/strong\u003e Contains small amounts of aluminum (from manufacturing glass vials); prolonged or high-dose infusions in premature infants or those with kidney failure can cause aluminum toxicity (bone or nervous system issues). Use pediatric electrolyte solutions in NICU when possible.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGeneral Precautions:\u003c\/strong\u003e Do not use if solution is discolored or particulate is visible. Monitor IV site and patient response continuously. Always refer to full prescribing information for detailed warnings and first aid in case of overdose.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eOverdose:\u003c\/strong\u003e Excessive administration can cause serious hypernatremia, fluid overload, hypertension, pulmonary edema or metabolic alkalosis. If overdose is suspected, stop infusion immediately, care for airway\/breathing\/circulation, and use appropriate measures (diuretics, respiratory support, electrolyte correction) under medical supervision.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePregnancy\/Lactation:\u003c\/strong\u003e Use only if clearly needed. No specific data on safety; sodium needs do not tend to change in pregnancy. Excretes in breast milk in very small amounts; consult doctor before use.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e Keep this product in its original carton at room temperature. Do not lock in med carts or expose to bright light. Proper storage ensures the stability of this \u003cstrong\u003evital IV medication\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eSodium Acetate Injection by Hikma is a crucial \u003cstrong\u003eelectrolyte therapy\u003c\/strong\u003e for hospitals and clinics, combining quality GMP manufacturing with essential clinical utility. It ensures patients receive safe, effective sodium supplementation and acid-base support during IV therapy.\u003c\/p\u003e","brand":"Hikma Injectables","offers":[{"title":"Default Title","offer_id":53989839339888,"sku":"00641-6262-01","price":19.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0996\/0350\/files\/Sodium-Acetate-Injection-2-mEq.jpg?v=1783362520","url":"https:\/\/www.mountainside-medical.com\/products\/sodium-acetate-injection-2-meq-ml-single-dose-50-ml","provider":"Mountainside Medical","version":"1.0","type":"link"}