Sodium Thiosulfate Injection 250 mg/mL Single Dose Vial 50 mL by Hope Pharma (RX)

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Sodium Thiosulfate Injection 250 mg Single Dose Vial by Hope Pharmaceuticals is a pharmaceutical product designed for various medical applications. Sodium thiosulfate is often used in the treatment of cyanide poisoning, severe calciphylaxis in patients with chronic kidney disease, and as an injection for certain other medical conditions as determined by a healthcare provider.

Manufacturer: Hope Pharmaceuticals
Active Ingredient: Sodium Thiosulfate
Strength: 250 mg per vial
Dosage Form: Single-dose vial for injection

Indications:

• Cyanide poisoning: Sodium thiosulfate is used as an essential antidote, usually administered in combination with sodium nitrite, to treat acute cyanide poisoning.
• Calciphylaxis: It is used in patients with chronic kidney disease undergoing dialysis who develop calciphylaxis, a rare and serious condition in which calcium accumulates in small blood vessels of the fat and skin tissues.
• Extravasation management: It helps in the management of extravasation (leakage of certain drugs into surrounding tissue) caused by certain chemotherapy agents.

Mechanism of Action:

Sodium thiosulfate works by converting toxic cyanide into thiocyanate, which is significantly less toxic and can be effectively excreted by the body through the kidneys. In the case of calciphylaxis, it helps dissolve calcium deposits and reduce inflammation.

Administration:

This product is meant for intravenous injection and should be administered under the supervision of a qualified healthcare professional. The exact dosage and administration depend on the patient's condition and the severity of symptoms.

Storage: Store at controlled room temperature. Protect from light and moisture. Keep out of reach of children.

Precautions:

• Ensure proper dilution and administration as per medical guidelines.
• Monitor patients for signs of allergic reactions, especially during the first administration.
• Use caution in patients with pre-existing kidney or liver conditions.

Adverse Reactions:

Common adverse reactions may include nausea, vomiting, headache, and mild allergic reactions. Serious adverse effects are rare but may include severe hypotension and hypersensitivity reactions.

Packaging:

Presented in a sterile, single-dose vial to ensure the highest quality and efficacy. Each vial is clearly labeled with the product name and dosage for easy identification.

For more detailed information, including potential drug interactions and detailed usage instructions, please refer to the product insert or contact Hope Pharmaceuticals directly.

Note: This description is provided for informational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for any questions regarding medication usage, effects, and suitability for specific conditions.