Uceris Rectal Foam Ulcerative Colitis Treatment, 28 Doses
$ 915.00 $ 1,495.95
Uceris (budesonide) Rectal Foam is a glucocorticosteroid used by gastroenterologist to help get mild to moderate active ulcerative colitis that extends from the rectum to the sigmoid colon under control (induce remission).
UCERIS® (budesonide) rectal foam is indicated for the induction of remission in patients with active, mild to moderate distal ulcerative colitis extending up to 40 cm from the anal verge.
UCERIS rectal foam is a glucocorticosteroid, formulated with budesonide, that's uniformly delivered to the distal colon, where it extends up to 40 cm from the anal verge to help patients with active, mild to moderate distal UC achieve remission.
Treatment with glucocorticosteroids, including UCERIS rectal foam, is associated with a suppression of endogenous cortisol concentrations and an impairment of the hypothalamic-pituitary-adrenal (HPA) axis function. These effects were
measured by determination of plasma cortisol concentrations and responses to adrenocorticotropin challenge (i.e., ACTH stimulation test) in 2 placebo-controlled, 6-week trials in patients with active disease. These
trials enrolled subjects with post-ACTH stimulation cortisol levels of >18 mcg/dL at baseline. Subjects received UCERIS rectal foam 2 mg or a placebo twice daily
for 2 weeks followed by once daily for 4 weeks. Normal morning serum cortisol levels >5 mcg/dL were maintained in 85% and 84% of UCERIS rectal foam treated subjects during Weeks 1 and 2 (twice daily treatment) and 93% and 94% during
Weeks 4 and 6 (once daily treatment), respectively. At baseline (predose), 84% of subjects in the UCERIS rectal foam group had a normal response to the ACTH challenge and at Week 6, 63% of subjects had a normal response to the ACTH challenge; in the placebo group, these values were 86% and 76%, respectively. ACTH stimulation test was not performed routinely during the twice daily treatment period (Weeks 1 and 2)
Brand: Salix Pharmaceuticals
Size: 28 doses (2mg)
Buy Uceris Rectal Foam Ulcerative Colitis Treatment online at Mountainside Medical Equipment.