Ketorolac Tromethamine Injection 30 mg Per 1 mL Vials x 25 Pack (Rx)

Fast-Acting, High-Potency, Non-Opioid Injectable Pain Relief for Acute Moderate to Severe Pain

Elevate your standard of care with Ketorolac Tromethamine Injection 30 mg per 1 mL by Sagent Pharmaceuticals, a trusted name in sterile hospital injectables. This prescription injectable NSAID offers clinically proven, rapid, and powerful analgesic and anti-inflammatory action—delivering the gold standard in short-term, non-opioid, moderate to severe pain control where fast, reliable results are needed.

Sagent Ketorolac Tromethamine Injection is a prescription medication used to relieve short-term, moderate to severe pain. It belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs) and works by reducing inflammation and blocking pain signals in the body. Each vial contains 30 mg of ketorolac tromethamine per 1 mL and is sold in a pack of 25 vials. It is typically administered through an injection by a healthcare professional. This medication should only be used for a short period of time and is not intended for long-term pain relief.

Uses and Clinical Applications

• Short-Term Management of Acute Moderate to Severe Pain: Effective for post-operative pain, orthopedic injury, trauma, musculoskeletal disorders, dental procedures.
• Hospital, Clinic, and Emergency Room Settings: Trusted by healthcare professionals for perioperative and in-hospital pain intervention.
• Ideal Opioid-Sparing Solution: When conventional NSAIDs are inadequate and opioid side effects are undesirable.

Applications

• IV (Intravenous) and IM (Intramuscular) Administration: For healthcare provider use ONLY
• Acute care settings: Hospitals, trauma centers, surgical centers, urgent care clinics
• Replacement for opioid injectables: Adjunct or alternative for controlled substance management protocols

Optimal non-opioid pain solution for hospitals & clinics — NDC 25021-0701-01 | UPC 325021701014

Benefits

• Non-Narcotic Alternative: Reduces opioid use and risk of dependency.
• Rapid Onset: Delivers fast, effective pain relief for acute and post-surgical pain.
• Premium Sterility: Each 1 mL vial is preservative-free and single-use, reducing infection risk.
• Bulk Economy (25 Vials/Pack): Optimal hospital, surgical suite, and emergency room inventory.
• FDA Approved and Quality-Assured: From Sagent Pharmaceuticals—a leader in hospital-grade medications.

Uses and Clinical Applications

• Short-Term Management of Acute Moderate to Severe Pain: Effective for post-operative pain, orthopedic injury, trauma, musculoskeletal disorders, dental procedures.
• Hospital, Clinic, and Emergency Room Settings: Trusted by healthcare professionals for perioperative and in-hospital pain intervention.
• Ideal Opioid-Sparing Solution: When conventional NSAIDs are inadequate and opioid side effects are undesirable.

Common Indications:

• Post-surgical pain control
• Severe injury-related pain
• Musculoskeletal and soft tissue pain
• Short-term pain after dental or orthopedic interventions

Applications

• IV (Intravenous) and IM (Intramuscular) Administration: For healthcare provider use ONLY
• Acute care settings: Hospitals, trauma centers, surgical centers, urgent care clinics
• Replacement for opioid injectables: Adjunct or alternative for controlled substance management protocols

How to Use Ketorolac Tromethamine Injection

1. Inspect vial for particulate matter and discoloration before use.
2. Use aseptic (sterile) technique for withdrawal and injection.
3. Single-dose vial: Administer full content; discard remainder after use.
4. Administer IM deeply into a large muscle, or inject slowly IV in a clinical setting.

NOTE: For licensed healthcare professionals only—NOT for self-injection or consumer use.

Dosage & Administration

Adults < 65 years with normal renal function

• IM: Start with 60 mg, then 30 mg every 6 hours as needed
• IV: 30 mg initial then 30 mg every 6 hours if required
• Max daily dose: 120 mg

Adults ≥ 65 years, or with renal impairment or < 50 kg

• IM/IV: 15 mg every 6 hours as needed
• Max daily dose: 60 mg

MAX DURATION: Therapy duration must NOT exceed 5 days due to increased risk of serious adverse events

Pediatric use: Not routinely recommended except by specialist

Drug Interactions

• Other NSAIDs/Aspirin: Increased risk of GI bleeding, nephrotoxicity
• Anticoagulants, Antiplatelets (Warfarin, Clopidogrel, Heparin): Elevated bleeding risk
• SSRIs/SNRIs, Corticosteroids: Cumulative risk of GI ulcers/bleeding
• ACE Inhibitors/Diuretics: Potential for renal injury
• Methotrexate or Lithium: NSAIDs can raise serum levels—monitor for toxicity

Side Effects and Warnings

Common Side Effects:

Nausea, abdominal pain, drowsiness, headache, injection site pain, indigestion, dizziness

Serious/Severe Risks:

• GI Bleeding/Perforation: Risk even without warning symptoms.
• Renal Toxicity: Renal impairment, especially with dehydration, elderly, or those with renal compromise.
• Increased Bleeding: Contraindicated in active bleeding or coagulation disorders.
• Anaphylaxis/Hypersensitivity: Bronchospasm, rash, hives—especially in aspirin-sensitive patients.
• Cardiovascular Events: Stroke, myocardial infarction (use with caution in preexisting heart disease)
• Contraindications:
  • Active or recent GI bleeding or peptic ulcers
  • Advanced renal impairment
  • Suspected or confirmed cerebrovascular bleeding
  • Labor and delivery
  • Use with other NSAIDs

Boxed Warning:

• NOT for chronic pain, minor pain, or pediatric use (unless directed).
• DO NOT use for more than 5 days.
• Contraindicated perioperatively in coronary artery bypass graft (CABG) surgery.

Specifications

• Brand/Manufacturer: Sagent Pharmaceuticals
• Formulation: Ketorolac Tromethamine, USP
• Strength: 30 mg/mL
• Package: 1 mL single dose vials, 25-pack
• NDC: 25021-0701-01
• UPC: 325021701014
• Administration Route: IV or IM injection by professional
• Preservative: None (preservative-free, single-use only)
• Storage: Store at 20° to 25°C (68° to 77°F); protect from light. Do not freeze.