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ear infection relief medicationsEar drops treat infection or inflammation, soften cerumen for removal, produce local anesthesia, or facilitate removal pf an insect. Instillation of eardrops is usually contraindicated if the patient has a perforated eardrum, but it may be permitted with certain medications and adherence to sterile technique. Some conditions may prohibit instillation of certain medications into the ear such as hydrocortisone use in patients with viral or fungal infections.