Headache Relief Medicines are used to effectively relieve pain caused by headaches and other related symptoms. They work by targeting the neurotransmitters associated with pain perception and relief; thus, the user experiences a lower intensity or sudden absence of throbbing, pulsating, or pounding symptoms. The most common type of Headache Relief Medicines are over-the-counter medications, such as ibuprofen and acetaminophen, that offer immediate temporary relief.