Atropine Sulfate USP (Monohydrate) For Compounding (API) (Rx)
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Atropine Sulfate, USP (Monohydrate) is a medication used for compounding. It is a synthetic alkaloid derived from the plant Atropa belladonna, commonly known as belladonna or deadly nightshade. It is a potent anticholinergic agent that blocks the effects of acetylcholine at muscarinic receptors, leading to a range of physiological effects such as decreased salivation, pupillary dilation, and cardiac and smooth muscle relaxation.
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Atropine sulfate is typically used in compounding to create various formulations for ophthalmic, gastrointestinal, and respiratory conditions. It can be prepared as an ophthalmic solution for dilation of the pupil for diagnostic or surgical procedures, or as an oral or injectable solution for the treatment of gastrointestinal or respiratory disorders such as irritable bowel syndrome, chronic obstructive pulmonary disease (COPD), and asthma. It may also be used as an antidote to poisoning by certain substances, such as organophosphate insecticides or other cholinesterase inhibitors.
When used for compounding, Atropine Sulfate, USP (Monohydrate) must be prepared according to strict guidelines to ensure its dose and efficacy. It should only be used under the supervision of a qualified healthcare professional and with proper medical equipment and monitoring. As with any medication, there may be possible side effects and interactions with other drugs, so it is important to follow proper compounding protocols and instructions from a healthcare professional.