Rocuronium Bromide Injection 10 mg per 5 mL Vial 10/Box
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Rocuronium Bromide Injection is widely used in anesthesia for rapid muscle relaxation during surgery and intubation. Doctors trust Rocuronium Bromide Injection for its quick effect and safety profile. Choose Rocuronium Bromide Injection for reliable patient care. Rocuronium Bromide Injection ensures optimal surgical outcomes.
Rocuronium Bromide Injection by Be Pharmaceuticals provides rapid and reliable neuromuscular blockade for a wide range of medical procedures. Each box contains ten sterile, preservative-free 5 mL vials, with each vial delivering 10 mg of rocuronium bromide for precise, titratable dosing. Trusted by anesthesiologists and critical care teams worldwide, this medication ensures optimal muscle relaxation during surgery, intubation, and mechanical ventilation.
What It’s Used For
Rocuronium bromide injection is a non-depolarizing neuromuscular blocking agent indicated for:
- Facilitation of tracheal intubation during routine sequence induction
- Skeletal muscle relaxation during surgical procedures
- Facilitation of mechanical ventilation in intensive care units
Dosage
- Adults (Intubation or Surgery): Initial dose is typically 0.6 mg/kg IV; intubating conditions usually achieved within 1–2 minutes.
- Maintenance: Supplemental doses of 0.1–0.2 mg/kg IV can be administered as needed.
- Pediatric and Elderly Dose: Dosage adjustments may be necessary based on age, underlying medical conditions, or concomitant medications.
- Special Populations: Lower doses may be required for patients with hepatic or renal impairment.
All dosing must be determined by a qualified healthcare professional based on patient weight, condition, and procedural requirements.
CDC Guidelines
While the Centers for Disease Control and Prevention (CDC) does not set specific guidelines for rocuronium use, always follow:
- Strict aseptic technique to reduce infection risk
- Standard protocols for medication management and storage (refrigerate as directed)
- Proper disposal of vials and syringes in sharps containers
- Frequent patient monitoring, particularly for respiratory depression in critical care settings
CDC’s overarching drug safety and infection control principles should always be applied.
Details & Features
- Concentration: 10 mg rocuronium bromide per 5 mL vial
- Packaging: 10 vials per box, ideal for hospital and clinical settings
- Rapid Onset: Produces muscle relaxation within 1–2 minutes
- Predictable Recovery: Duration of action ranges from 30–60 minutes, depending on dose and patient factors
- Sterile & Preservative-Free: Reduces risk of contamination or allergic reactions
- Latex-Free Packaging: Safe for patients with latex sensitivities
Mechanism of Action
Rocuronium bromide is a non-depolarizing neuromuscular blocking agent. It competitively binds to nicotinic acetylcholine receptors at the motor endplate, blocking the action of acetylcholine and resulting in skeletal muscle paralysis. This mechanism facilitates procedures requiring intubation, optimal surgical conditions, or controlled mechanical ventilation.
Directions
- Administration: Administer intravenously by a trained healthcare professional.
- Preparation: Ensure vial contents are clear and particle-free. Use immediately after opening.
- Dosage: Calculate dose based on weight; administer as a slow IV bolus injection.
- Monitoring: Continuously monitor patient respiratory status, neuromuscular function, and vital signs throughout use.
- Reversal: Use appropriate neuromuscular blockade reversal agents (e.g., neostigmine, sugammadex) at procedure completion, as directed.
Warnings
- For Hospital/Clinical Use Only: Do not use outside a setting where appropriate airway management and resuscitative equipment are available.
- Paralysis Risk: Causes complete muscle paralysis, including respiratory muscles—ensure adequate ventilatory support is always available.
- Hypersensitivity: Do not use in patients with known hypersensitivity to rocuronium or other neuromuscular blocking agents.
- Drug Interactions: Potentiated by certain antibiotics, inhaled anesthetics, and magnesium—review all concomitant medications.
- Prolonged Blockade: In patients with hepatic/renal impairment or certain neuromuscular disorders.
- Pregnancy/Breastfeeding: Use only if clearly needed and prescribed by a physician.
Side Effects
- Common: Temporary muscle weakness or paralysis, injection site reactions
- Moderate: Hypotension, tachycardia or bradycardia, mild allergic reactions
- Serious: Anaphylaxis, prolonged apnea or respiratory depression, arrhythmias, residual muscle weakness
Report any adverse reactions immediately to the supervising clinician and follow institutional protocols for management.
Choose Rocuronium Bromide Injection by Be Pharmaceuticals for consistent, effective muscle relaxation and secure patient control during anesthesia and critical care.