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Rocuronium Bromide Injection 10 mg per 5 mL Vial 10/Box

Sale 24%
Original price $ 74.95
Current price $ 57.00
SKU 71839-0141-10
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Rocuronium bromide is a fast-acting, intermediate-duration, non-depolarizing neuromuscular blocking agent used as an adjunct to general anesthesia. It is given intravenously by healthcare professionals to relax skeletal muscles during surgical procedures or when mechanical ventilation is required.

Rocuronium Bromide Injection is widely used in anesthesia for rapid muscle relaxation during surgery and intubation. Doctors trust Rocuronium Bromide Injection for its quick effect and safety profile. Choose Rocuronium Bromide Injection for reliable patient care. Rocuronium Bromide Injection ensures optimal surgical outcomes.

Rocuronium Bromide Injection by Be Pharmaceuticals provides rapid and reliable neuromuscular blockade for a wide range of medical procedures. Each box contains ten sterile, preservative-free 5 mL vials, with each vial delivering 10 mg of rocuronium bromide for precise, titratable dosing. Trusted by anesthesiologists and critical care teams worldwide, this medication ensures optimal muscle relaxation during surgery, intubation, and mechanical ventilation.

What It’s Used For

Rocuronium bromide injection is a non-depolarizing neuromuscular blocking agent indicated for:

  • Facilitation of tracheal intubation during routine sequence induction
  • Skeletal muscle relaxation during surgical procedures
  • Facilitation of mechanical ventilation in intensive care units

Dosage

  • Adults (Intubation or Surgery): Initial dose is typically 0.6 mg/kg IV; intubating conditions usually achieved within 1–2 minutes.
  • Maintenance: Supplemental doses of 0.1–0.2 mg/kg IV can be administered as needed.
  • Pediatric and Elderly Dose: Dosage adjustments may be necessary based on age, underlying medical conditions, or concomitant medications.
  • Special Populations: Lower doses may be required for patients with hepatic or renal impairment.

All dosing must be determined by a qualified healthcare professional based on patient weight, condition, and procedural requirements.

CDC Guidelines

While the Centers for Disease Control and Prevention (CDC) does not set specific guidelines for rocuronium use, always follow:

  • Strict aseptic technique to reduce infection risk
  • Standard protocols for medication management and storage (refrigerate as directed)
  • Proper disposal of vials and syringes in sharps containers
  • Frequent patient monitoring, particularly for respiratory depression in critical care settings

CDC’s overarching drug safety and infection control principles should always be applied.

Details & Features

  • Concentration: 10 mg rocuronium bromide per 5 mL vial
  • Packaging: 10 vials per box, ideal for hospital and clinical settings
  • Rapid Onset: Produces muscle relaxation within 1–2 minutes
  • Predictable Recovery: Duration of action ranges from 30–60 minutes, depending on dose and patient factors
  • Sterile & Preservative-Free: Reduces risk of contamination or allergic reactions
  • Latex-Free Packaging: Safe for patients with latex sensitivities

Mechanism of Action

Rocuronium bromide is a non-depolarizing neuromuscular blocking agent. It competitively binds to nicotinic acetylcholine receptors at the motor endplate, blocking the action of acetylcholine and resulting in skeletal muscle paralysis. This mechanism facilitates procedures requiring intubation, optimal surgical conditions, or controlled mechanical ventilation.

Directions

  1. Administration: Administer intravenously by a trained healthcare professional.
  2. Preparation: Ensure vial contents are clear and particle-free. Use immediately after opening.
  3. Dosage: Calculate dose based on weight; administer as a slow IV bolus injection.
  4. Monitoring: Continuously monitor patient respiratory status, neuromuscular function, and vital signs throughout use.
  5. Reversal: Use appropriate neuromuscular blockade reversal agents (e.g., neostigmine, sugammadex) at procedure completion, as directed.

Warnings

  • For Hospital/Clinical Use Only: Do not use outside a setting where appropriate airway management and resuscitative equipment are available.
  • Paralysis Risk: Causes complete muscle paralysis, including respiratory muscles—ensure adequate ventilatory support is always available.
  • Hypersensitivity: Do not use in patients with known hypersensitivity to rocuronium or other neuromuscular blocking agents.
  • Drug Interactions: Potentiated by certain antibiotics, inhaled anesthetics, and magnesium—review all concomitant medications.
  • Prolonged Blockade: In patients with hepatic/renal impairment or certain neuromuscular disorders.
  • Pregnancy/Breastfeeding: Use only if clearly needed and prescribed by a physician.

Side Effects

  • Common: Temporary muscle weakness or paralysis, injection site reactions
  • Moderate: Hypotension, tachycardia or bradycardia, mild allergic reactions
  • Serious: Anaphylaxis, prolonged apnea or respiratory depression, arrhythmias, residual muscle weakness

Report any adverse reactions immediately to the supervising clinician and follow institutional protocols for management.

Choose Rocuronium Bromide Injection by Be Pharmaceuticals for consistent, effective muscle relaxation and secure patient control during anesthesia and critical care.

Rocuronium Bromide Injection – Frequently Asked Questions (FAQs)
  • What is Rocuronium Bromide Injection used for?

    Rocuronium Bromide is a muscle relaxant (neuromuscular blocking agent) used during surgery or mechanical ventilation. It is commonly administered to help relax muscles for intubation (placing a breathing tube) and during general anesthesia.

  • How is Rocuronium Bromide administered?

    It is given as an intravenous (IV) injection or infusion by an anesthesiologist or trained healthcare provider in a hospital or surgical setting.

  • How does Rocuronium work?

    Rocuronium blocks the signals from nerves to muscles, causing temporary paralysis of the skeletal muscles. This allows for easier intubation and surgery by preventing involuntary movement.

  • How long do the effects of Rocuronium last?

    The muscle relaxation typically lasts 30–60 minutes, depending on the dose, with effects wearing off gradually. Recovery time can be influenced by the patient's health, the dose given, and whether reversal agents are used.

  • Can the effects of Rocuronium be reversed?

    Yes. A medication called sugammadex or, less commonly, neostigmine can be used to quickly reverse the effects of rocuronium and restore normal muscle function after surgery.

  • What are the common side effects of Rocuronium?

    Most people do not experience side effects when under anesthesia, but possible reactions can include low blood pressure, increased or decreased heart rate, flushing, or prolonged paralysis. Allergic reactions are rare but possible.

  • Who should NOT receive Rocuronium?

    Patients with known hypersensitivity to rocuronium or other neuromuscular blocking agents should not receive it. Those with certain neuromuscular diseases or allergies should inform their healthcare provider before surgery.

  • Does Rocuronium interact with other drugs?

    Yes, rocuronium can interact with other medications such as certain antibiotics, magnesium, lithium, and some seizure medications. Always provide a complete medication list to your healthcare team before surgery.

  • Is Rocuronium safe for children and older adults?

    Rocuronium can be used in both children and adults. Dosing may be adjusted based on age, size, and health status. Caution is taken in the elderly and individuals with liver or kidney impairment.

  • Will I be awake or aware after receiving Rocuronium?

    No. Rocuronium only causes muscle paralysis and is always used with adequate anesthesia. It is never used alone without sedation or anesthesia, as it provides no pain relief or loss of consciousness.

  • How is my breathing managed while I am paralyzed by Rocuronium?

    Your breathing will be assisted with a ventilator while under the effects of rocuronium, as you will not be able to breathe on your own until the drug wears off or is reversed.

  • Can Rocuronium cause allergic reactions?

    Yes, though rare, severe allergic (anaphylactic) reactions can occur, especially in individuals with a history of allergies to muscle relaxants. Emergency treatment is available in the operating room.

  • How is Rocuronium stored and prepared?

    It is stored as a refrigerated solution in hospitals and prepared by trained pharmacy or clinical staff prior to use.

  • What should I tell my doctor before receiving Rocuronium?

    Inform your doctor of all current medications, past reactions to anesthesia, neuromuscular diseases, allergies, and any history of kidney, liver, or heart problems.

  • Is there any residual muscle weakness after Rocuronium wears off?

    Most patients regain normal muscle function rapidly with proper monitoring and care. Rarely, some individuals may experience temporary weakness or residual paralysis, especially with underlying neuromuscular disorders.

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