Misoprostol Tablets

Misoprostol is a medication that belongs to a class of drugs called prostaglandin analogs. It mimics the action of prostaglandin E1 in the body.

Misoprostol tablets are a medication with several important uses in medicine, primarily related to the uterus and stomach. The active ingredient is misoprostol, which is a prostaglandin analog.

Prevention of Stomach Ulcers Indication: Often prescribed to prevent gastric ulcers in patients taking long-term non-steroidal anti-inflammatory drugs (NSAIDs), like ibuprofen or aspirin. How it works: By protecting the stomach lining from ulceration caused by NSAID use. Gynecological and Obstetric Uses Inducing Labor: Can be used to ripen the cervix and induce labor in pregnant women, when medically indicated. Medical Abortion: Used in combination with another drug (mifepristone or sometimes methotrexate) to terminate early pregnancies. How it works: Causes contractions of the uterus, leading to expulsion of pregnancy tissue. Treatment of Missed or Incomplete Miscarriage: Helps expel retained pregnancy tissue. Postpartum Hemorrhage: Sometimes used to help control severe bleeding after childbirth by contracting the uterus.

Tablet forms: Swallowed, dissolved under the tongue (sublingual), or placed inside the cheek (buccal) or vagina (vaginally), depending on medical indication.

Gastrointestinal: Diarrhea, stomach cramps, nausea, vomiting, flatulence. Gynecological: Uterine cramps, vaginal bleeding, headache, chills, fever

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Misoprostol is primarily used during pregnancy for medical abortion (early termination of pregnancy), to manage miscarriage (missed abortion), or to induce labor in a medically prescribed setting. It works by causing the uterus to contract and expel its contents. It’s also used to prevent and treat postpartum hemorrhage (excessive bleeding after childbirth).

Typically, bleeding and tissue will begin to come out first after taking misoprostol. You may notice blood clots and pregnancy tissue passing from the vagina, which indicates that the uterus is being emptied.

Medical guidelines recommend 4 to 6 Misoprostol tablets (800 mcg to 1200 mcg, usually 200 mcg per tablet) either buccally (in the cheek), vaginally, or sublingually (under the tongue) depending on your doctor's instructions and gestational age. Always follow your licensed healthcare provider’s advice for the correct dosage.

Misoprostol usually starts working within 1–4 hours after administration. Expect cramping, bleeding, or passing of tissue as early as 30 minutes, but most women experience effects within a few hours.

You may pass pregnancy tissue within 4–6 hours after taking Misoprostol, but in some cases, it can take up to 24 hours for complete expulsion. If you haven’t experienced expected results, consult your healthcare provider.

Yes, the World Health Organization (WHO) and leading medical institutions endorse home use of Misoprostol under medical guidance. Always ensure you are properly prepared, in a safe environment, and have access to medical assistance if needed.

The main signs include heavy bleeding, passing of clots/tissue, and reduction in pregnancy symptoms. A follow-up with ultrasound or clinical exam is needed to confirm a complete abortion or miscarriage.