Nitro-Bid Ointment

Nitro-Bid Ointment contains nitroglycerin, a potent vasodilator that widens blood vessels, improves blood flow, and relieves pain. It is primarily used to: Prevent and treat angina (chronic chest pain from coronary artery disease) Relieve pain and promote healing for chronic anal fissures and hemorrhoids (off-label)

Action begins within 15–60 minutes for angina and chest pain and may be faster for external/rectal use. For cardiac patients, nitroglycerin ointment helps prevent chest pain episodes with scheduled, regular application.

Most patients apply Nitro-Bid and leave it on for 12 hours, then remove and allow a “nitrate-free interval” (typically 12 hours off) to prevent tolerance. For anal fissure or hemorrhoid use, follow your doctor’s application schedule.

While not FDA-approved, nitroglycerin ointment is sometimes used off-label in small amounts to relieve pain, spasm, and promote healing in severe hemorrhoids or anal fissures. Talk to your doctor first.

No, Nitro-Bid and all nitroglycerin ointments are prescription-only in the U.S. and most countries due to strong vasodilating effects and potential side effects.

Those with low blood pressure (hypotension) Allergy to nitroglycerin or nitrates Severe anemia or increased intracranial pressure Recent use of erectile dysfunction medication (Viagra, Cialis, Levitra) Always discuss your full medical history with your prescriber

For chest pain prevention: Success varies, but most patients have significantly reduced angina attacks. For anal fissures: Healing rates of 50–70% are reported after 6–8 weeks of treatment.

Cardiac use: Center of the chest, arms, or upper torso; rotate application sites to avoid skin irritation. Anal fissures or hemorrhoids: Apply a small amount directly to the anal canal with a gloved finger or applicator.

Price varies by location and insurance: typically $40–$120 per tube in the U.S. Generic nitroglycerin ointments (2%) are often available at lower cost.

Dietary fiber, warm sitz baths, and coconut oil are promoted for mild fissures. Topical calcium channel blockers (diltiazem, nifedipine) and medical honey are other options.

Headache (most common, due to vasodilation) Lightheadedness or dizziness Local irritation or redness Rare: Allergic reactions, hypotension

Improvements often seen in 1–2 weeks; complete healing in 6–8 weeks with regular use.

Wear gloves and wash hands after application. Apply only the amount prescribed. Avoid standing quickly after application. Remove old ointment before reapplying a new dose. Rotate sites for cardiac use to prevent rash.

Standard application for 12 hours “on,” then 12 hours “off.” For anal fissures, as directed by your doctor.

Safe and effective when used as prescribed and with proper precautions. Regular follow-up ensures side effects are managed and doses are adjusted as needed.

May cause dangerous drops in blood pressure, severe headache, or fainting. Never use without a prescription and medical advice.

Yes, it can significantly lower blood pressure, especially if you are already taking antihypertensives or apply more than prescribed.

Vasodilation in blood vessels increases blood flow, especially to the scalp and brain, leading to headaches—a well-known side effect. This often lessens with regular use or dose adjustment.

Nitroglycerin improves blood flow, which can indirectly enhance healing (especially in chronic anal fissures), but is not a direct wound healing agent for general skin wounds.

Relief may begin within 15 minutes to 1 hour, depending on area and medical indication.

FDA-approved, gold standard nitroglycerin ointment Reliable for both chronic angina prevention and proven healing of anal fissures Easy application with precise dosing (measuring papers or applicators) Available in cost-saving generic nitroglycerin ointment options Physician recommended and pharmacist trusted Ointment base for long-lasting effect and minimal mess Secure, tamper-resistant packaging with clear instructions