Hyalgan Injection Sodium Hyaloronate Syringe, 2 mL (Rx)

Hyalgan Injection is a trusted and clinically proven treatment for relieving knee pain associated with osteoarthritis, offering significant improvement in joint mobility and overall quality of life. Many patients and healthcare professionals prefer Hyalgan Injection because it provides targeted lubrication and cushioning to the knee joint, helping to reduce pain and inflammation for extended periods. Hyalgan Injection is administered directly into the affected joint, making it an effective alternative for those who have not found relief with oral medications or physical therapy. If you are seeking long-lasting knee pain relief, Hyalgan Injection is a safe and reliable option supported by extensive research and positive patient outcomes. Hyalgan Osteoarthritis Knee Pain Relief Injections is a medical treatment used to relieve pain and improve function in people with osteoarthritis of the knee. Hyalgan is a form of hyaluronic acid, a naturally occurring substance in the body that helps to cushion and lubricate joints. Hyalgan is given as an injection into the knee joint.

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Hyalgan Injection by Fidia Pharma is a sterile, pre-filled 2 mL syringe containing high molecular weight sodium hyaluronate, designed for intra-articular injection to relieve pain in osteoarthritis (OA) of the knee. As a viscosupplement, Hyalgan acts to restore the natural lubricating and shock-absorbing properties of synovial fluid, offering effective, non-opioid pain relief for patients inadequately responsive to simple analgesics or non-pharmacologic therapy.

What Hyalgan Is Used For

Hyalgan (sodium hyaluronate) is indicated for:

• Relief of knee pain due to osteoarthritis when conservative treatments (e.g., exercise, physical therapy, acetaminophen) are inadequate.
• Improving mobility and patient function in OA of the knee.

Off-label Uses (at the physician’s discretion):

• May be considered for OA in other synovial joints, based on clinical judgment.

Dosage and Administration

• Typical regimen: 1 injection (2 mL) administered intra-articularly into the affected knee once a week for 3 to 5 weeks.
  • Maximum: 5 injections per treatment course.
• Repeat cycles: May be repeated as symptoms return, under physician guidance.

CDC Guidelines and Current Practice

While the CDC does not issue product-specific guidelines for viscosupplementation, the CDC's OA treatment recommendations highlight:

• Start with non-pharmacologic therapies first (exercise, weight loss).
• Consider intra-articular hyaluronate injections, like Hyalgan, if oral NSAIDs/acetaminophen are insufficient or not tolerated. See the CDC Osteoarthritis Treatment Page and recent American College of Rheumatology (ACR) guidelines for updated clinical recommendations.

Details and Features

• Strength/Formulation: Each prefilled syringe contains 20 mg/2 mL sodium hyaluronate.
• Sterility: Sterile, preservative-free, ready-to-use syringe.
• Administration: For intra-articular injection by a qualified healthcare professional only.
• Brand: Fidia Pharma, a leader in hyaluronic acid therapies.
• NDC: 89122-0724-20
• Storage: Refrigerate at 2° to 25°C (36° to 77°F); do not freeze.
• Single use only; discard any unused portion.

Mechanism of Action

• Sodium hyaluronate is a natural polysaccharide found in synovial fluid.
• By supplementing degraded synovial fluid in OA knees, Hyalgan restores viscosity and elasticity, enhances shock absorption, and improves joint lubrication.
• This reduces joint pain, increases mobility, and may delay the need for surgery.

Directions for Use

1. Administration: Only a trained healthcare professional should inject Hyalgan directly into the knee joint.
2. Preparation: Use aseptic technique. Remove joint effusion before injection if present.
3. Instructions for Patients:
   • Avoid strenuous activities (e.g., jogging, tennis, heavy lifting) for 48 hours post-injection.
   • Report signs of infection, allergic reaction, or severe pain to your physician immediately.

Warnings and Precautions

• Do not use with known hypersensitivity to sodium hyaluronate or avian proteins.
• Not for intravenous or intramuscular use.
• Bleeding Disorders: Use caution in patients with anticoagulant therapy or bleeding disorders.
• Infection: Do not inject into infected or severely inflamed joints.
• Pregnancy and Nursing: Use only if clearly needed and under physician direction.
• No proven benefit for patients with advanced OA requiring joint replacement.

Possible Side Effects

Most common:

• Local injection site pain or swelling
• Mild joint stiffness or warmth
• Local skin reaction or rash

Less common:

• Joint infection (septic arthritis—rare but serious)
• Allergic, hypersensitivity reactions (anaphylaxis—rare)
• Bruising or bleeding at injection site

Seek urgent medical attention for:

• Severe joint pain
• Signs of infection (redness, warmth, fever)
• Swelling that persists or systemic allergic reactions

Clinically proven viscosupplement for osteoarthritis knee pain. Non-opioid, locally acting, and physician-trusted.

Buy Hyalgan Sodium Hyaluronate Injection, 2 mL – Fidia Pharma