Supartz FX Injection (Sodium Hyaluronate) 10mg/mL Prefilled Syringe 2.5 mL

Supartz FX (Sodium Hyaluronate) Injection is a high-purity viscoelastic solution packaged in a convenient 2.5 mL prefilled syringe. Designed by Bioventus, this prescription medication provides effective, targeted relief for knee pain due to osteoarthritis, helping patients regain mobility and improve their quality of life.

What Is Supartz FX Used For?

Supartz FX is indicated for:

• Alleviating knee pain associated with osteoarthritis (OA) in patients who have not responded adequately to conservative nonpharmacologic therapy and simple analgesics like acetaminophen.
• Restoring normal joint lubrication and shock absorption properties within the synovial fluid of the knee.
• Providing temporary pain relief and improved function, allowing for increased physical activity and enhanced daily living.

Product Details & Features

• Active Ingredient: Sodium Hyaluronate (10 mg/mL)
• Concentration: 10mg/mL
• Total Volume: 2.5 mL prefilled syringe
• Administration Route: Intra-articular injection (directly into the knee joint)
• Sterile, Non-Pyrogenic, Non-Animal Derived
• Manufactured By: Bioventus
• Packaging: Ready-to-use prefilled syringe for convenient and accurate dosing

Key Features

• Natural Lubricant: Replenishes hyaluronic acid in knee joints, mimicking the natural joint fluid.
• Clinically Proven: Demonstrated in clinical studies to reduce pain and improve joint function.
• Well-Tolerated: Low risk of systemic side effects, offering a safe local therapy.
• Convenient Administration: Prefilled syringe for quick, efficient, and accurate intra-articular delivery by qualified healthcare professionals.

Directions for Use

• This product is for intra-articular (in the joint) use only, and must be administered by a healthcare professional experienced in knee injections.
• Patient should relax knee joint for the injection.
• Area over the joint should be sterilized prior to injection.
• Remove all synovial fluid or effusion from the knee using an aspirating needle before injection.
• Inject the full 2.5 mL dose into the knee joint space.
• Supartz FX is typically given as a series of three to five weekly injections, depending on patient response and clinical guidance.

Dosage

• Recommended Dose: One 2.5 mL injection directly into the knee joint once weekly for a series of three to five injections.
• Use the entire contents of the prefilled syringe for each injection.
• Only one knee may be treated at a time.
• Repeat treatment may be considered if symptoms recur, with a similar dosing schedule.

CDC Guidelines & Clinical Recommendations

• Injections should be performed using strict aseptic technique to prevent the risk of joint infection.
• Only healthcare providers trained in joint injection techniques should administer Supartz FX.
• CDC infection control recommendations for intra-articular injections must be followed at every administration: Hand hygiene, use of sterile gloves, cleaning the skin with appropriate antiseptic, and using sterile equipment.
• Patient monitoring for immediate allergic or local reactions is advised post-injection.

Warnings

• Not for intravenous or intramuscular use.
• Contraindicated in patients with known hypersensitivity to hyaluronate products.
• Do not use in the presence of infections or skin diseases at the injection site.
• Not recommended in patients with active joint infections or skin diseases in the area of the injection site.
• Full range of movement should be avoided immediately after injection; vigorous activities should be avoided for at least 48 hours post-injection.
• Safety and effectiveness in pediatric patients, pregnant or lactating women have not been established.
• Use caution in patients allergic to avian proteins, feathers, or egg products.

Possible Side Effects

Common Side Effects:

• Pain, swelling, heat, rash, itching, or redness at the injection site
• Joint stiffness or effusion (fluid accumulation)
• Mild local discomfort after injection

Less Common/Serious Side Effects:

• Infection in the joint (septic arthritis)
• Allergic reactions (including anaphylaxis — rare)
• Bleeding or bruising at injection site

If you notice any signs of joint infection (fever, chills, severe pain, or redness at the joint), seek medical attention immediately.

Supartz FX by Bioventus—an effective, trusted option for osteoarthritis-related knee pain relief, offering enhanced comfort and mobility through safe and proven science.