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Daptomycin Injection 500 mg Powder Vial (RX) *Refrigerated

Sale 40%
Original price $ 125.00
Current price $ 75.00
SKU 31722-0216-01
*Mountainside Medical does not fill personal prescriptions Medical Professional License Required to Unlock Account

How to Order:

Send an email request to: sales@mountainside-medical.com

You will receive instructions on how to create an account along with Rx Ordering Details.

(Note: Acceptable licenses must have Prescriptive Authority in the license issuing state.)
Daptomycin for injection is a cyclic lipopeptide antibiotic used to treat severe bacterial infections of the skin and bloodstream, including infections caused by drug-resistant bacteria such as MRSA. It is given intravenously by a healthcare provider and is not effective against viral illnesses such as the common cold or flu.

Daptomycin for Injection is an antibiotic used to treat certain bacterial infections. It is particularly effective against Gram-positive bacteria. Daptomycin works by disrupting the bacterial cell membrane, leading to cell death. It is commonly used to treat complicated skin and skin structure infections, bacteremia, and right-sided infective endocarditis caused by susceptible strains of microorganisms. The medication is administered intravenously and is typically reserved for serious infections or when other antibiotics are not suitable. As with any antibiotic, it's important to use it under the guidance of a healthcare professional to ensure its effectiveness and to reduce the risk of resistance.

Daptomycin for Injection by Camber Pharma delivers a potent antibiotic solution designed to treat serious bacterial infections. Each 500 mg vial is tailored for intravenous use, ensuring rapid action against a range of Gram-positive bacteria.

Uses:

Daptomycin is used for:

  • Treating complicated skin and skin structure infections (cSSSI)
  • Managing Staphylococcus aureus bloodstream infections (bacteremia), including right-sided infective endocarditis

Dosage:

  • Specific dosage depends on the type and severity of infection.
  • Typical dosing for cSSSI is 4 mg/kg once daily.
  • For bacteremia, 6 mg/kg once daily is often recommended.
  • Administered via intravenous infusion, usually over 30 minutes.

CDC Guidelines:

The CDC emphasizes the importance of appropriate antibiotic use to prevent resistance. Daptomycin should be used according to susceptibility patterns and in consultation with infectious disease specialists.

Details and Features:

  • Concentration: 500 mg per vial
  • Formulation: Sterile powder for reconstitution
  • Brand: Camber Pharma
  • NDC: 31722-0216-01

Mechanism of Action:

Daptomycin disrupts bacterial cell membrane function by binding to it in a calcium-dependent manner, leading to rapid depolarization. This loss of membrane potential inhibits protein, DNA, and RNA synthesis, resulting in bacterial cell death.

Directions:

  1. Reconstitute the vial with the recommended diluent.
  2. Administer through intravenous infusion under professional supervision.
  3. Do not shake vigorously; swirl gently to dissolve.
  4. Use immediately after preparation to ensure sterility.

Warnings:

  • Monitor for muscle pain or weakness, as Daptomycin can cause myopathy.
  • Regularly check creatine phosphokinase (CPK) levels.
  • Not recommended for pneumonia treatment.
  • Use with caution in patients with renal impairment.

Side Effects:

Possible side effects include:

  • Gastrointestinal disturbances (nausea, diarrhea)
  • Headache
  • Insomnia
  • Elevated liver enzymes
  • Muscle pain or weakness

Consult Healthcare Provider:

Daptomycin should always be administered under the guidance of a qualified healthcare provider. Report any side effects promptly, especially muscle-related symptoms or signs of allergic reactions, for timely intervention.

Daptomycin Injection 500 mg Powder Vial (RX) *Refrigerated
Daptomycin Injection 500 mg Powder Vial (RX) *Refrigerated
$ 125.00 $ 75.00
🔒 Medical License Required
Daptomycin Injection 500 mg – Frequently Asked Questions (FAQs)
  • What is Daptomycin Injection used for?

    Daptomycin is an intravenous antibiotic used to treat serious or complicated bacterial infections, including skin and soft tissue infections, bloodstream infections (bacteremia), and right-sided infective endocarditis caused by Gram-positive bacteria, including MRSA (methicillin-resistant Staphylococcus aureus).

  • How is Daptomycin administered?

    It is given as an intravenous (IV) infusion, usually once daily, by a healthcare professional in a hospital or outpatient clinic setting.

  • What are the common side effects of Daptomycin?

    Common side effects include diarrhea, nausea, vomiting, constipation, headache, dizziness, insomnia, rash, and injection site reactions. Muscle pain or weakness and increased levels of muscle enzymes (CPK) are important side effects to monitor.

  • Can Daptomycin cause serious side effects?

    Yes. Rare but serious side effects include severe muscle damage (myopathy/rhabdomyolysis), allergic reactions, pneumonia progressing to eosinophilic pneumonia, and nerve damage (peripheral neuropathy). Notify your doctor promptly if you develop unexplained muscle pain, weakness, or breathing difficulties.

  • How long is the course of Daptomycin treatment?

    Duration depends on the infection being treated, but courses typically range from 7–14 days for skin infections to several weeks for endocarditis or severe bloodstream infections.

  • Are there any blood tests required while taking Daptomycin?

    Yes. Your healthcare provider will monitor your creatine phosphokinase (CPK) levels, kidney function, and sometimes liver function during treatment to check for muscle injury and monitor overall health.

  • Can Daptomycin be used in patients with kidney problems?

    Dose adjustments may be needed for patients with kidney impairment, and kidney function should be closely monitored.

  • Does Daptomycin interact with other medications?

    Yes. The risk of muscle side effects is higher if used with statins or other medications that may affect muscles. Always provide your healthcare provider with a full list of your medications.

  • Can Daptomycin be used in children?

    Daptomycin is approved for certain infections in pediatric patients (1 year and older for skin infections; 1–17 years for bacteremia). Dosing is adjusted by age and weight.

  • Can Daptomycin be given to people who have allergies to penicillin or cephalosporins?

    Daptomycin is structurally different than penicillins and cephalosporins and may be a safe alternative for those with allergies to beta-lactam antibiotics. Discuss any allergies with your doctor.

  • What should I do if I miss a dose?

    Notify your healthcare provider right away. Do not double dose—your provider will advise on rescheduling infusions.

  • Can I use Daptomycin if I am pregnant or breastfeeding?

    There is limited data on use during pregnancy and breastfeeding. Use only if needed and prescribed, with close monitoring and after discussion of risks and benefits with your healthcare provider.

  • How should Daptomycin Injection be stored?

    The powder should be stored at room temperature until reconstituted. After mixing, use immediately or store as instructed by your pharmacist or healthcare provider.

  • Can I drink alcohol while taking Daptomycin?

    There are no specific interactions, but alcohol can complicate certain infections and may increase risk of side effects. Ask your healthcare provider for advice.

  • Is monitoring needed after Daptomycin treatment ends?

    It may be recommended to follow-up, especially if you experienced muscle problems, kidney changes, or side effects during treatment.

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