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Ceftriaxone Sodium Injection 500 mg 1 mL vials on a sterile tray, crucial for antibiotic therapy and combating bacterial infections efficiently.
Ceftriaxone Sodium Injection 500 mg 1 mL vials on a sterile tray, crucial for antibiotic therapy and combating bacterial infections efficiently.

Ceftriaxone Sodium Injection 500 mg 1 mL Vials, 10/Pack (Rx)

by Pfizer Injectables
Sale 38%
$ 34.95
$ 21.50
SKU 0409-7338-01
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Ceftriaxone Sodium Injection 500 mg is used to treat a wide range of bacterial infections. It belongs to the cephalosporin class of antibiotics and works by inhibiting cell wall synthesis, effectively eliminating bacteria. This antibiotic is commonly used for infections such as pneumonia, urinary tract infections, skin infections, and sexually transmitted infections like gonorrhea. It is administered intravenously or intramuscularly, ensuring rapid delivery to combat severe or systemic infections, providing effective treatment to support recovery and prevent complications.

Ceftriaxone Sodium Injection is a broad-spectrum, third-generation cephalosporin antibiotic used for the treatment of various bacterial infections. It is highly effective against a wide range of Gram-positive and Gram-negative bacteria. This product by Pfizer Injectables is provided in a dosage form of 500 mg of ceftriaxone per 1 mL vial, and it is packaged in packs containing 10 vials.

Details and Features:

Dosage Form: 500 mg of Ceftriaxone per vial
Volume: Each vial contains powder for reconstitution to achieve the desired concentration for injection
Packaging: 10 vials per pack
Use: Indicated for intramuscular (IM) or intravenous (IV) administration
Application: Commonly used for treating infections such as pneumonia, urinary tract infections, gonorrhea, septicemia, meningitis, and surgical prophylaxis

Mechanism of Action:

Ceftriaxone works by inhibiting bacterial cell wall synthesis. It targets the penicillin-binding proteins (PBPs) within the bacterial cell wall, disrupting the cross-linking of peptidoglycan chains, which are crucial for bacterial cell wall structural integrity. This leads to cell lysis and death, particularly in actively dividing bacteria.

Warnings:

  • Hypersensitivity: Contraindicated in patients with known hypersensitivity to ceftriaxone, cephalosporins, or beta-lactam antibiotics.
  • Interaction with Calcium-Containing IV Solutions: Reconstituted Ceftriaxone should not be mixed or simultaneously infused with calcium-containing IV solutions due to the risk of crystalline precipitate formation.
  • Neonatal Safety: Use is cautioned in neonates due to the risk of bilirubin encephalopathy.
  • Clostridium difficile-Associated Diarrhea (CDAD): Prolonged use of antibiotics like ceftriaxone may lead to overgrowth of non-susceptible organisms, including fungi. Monitoring for signs of pseudomembranous colitis is advised.
  • Renal and Hepatic Impairment: Use cautiously and adjust dosing in patients with significant renal and combined renal/hepatic impairment.

Side Effects:

While generally well-tolerated, Ceftriaxone may have some side effects, including:

  • Local Reactions: Pain, induration, and tenderness at the IM injection site; potential thrombophlebitis after IV administration
  • Gastrointestinal: Diarrhea, nausea, vomiting, risk of CDAD with severe cases
  • Hypersensitivity Reactions: Rash, pruritus, fever, and, on rare occasions, a more severe anaphylactic reaction
  • Hematologic: Eosinophilia, thrombocytosis, leukopenia
  • Hepatic: Transient elevations in liver enzymes

Ceftriaxone administration should always be conducted under the guidance of a healthcare professional with appropriate dosing and observation to manage any adverse effects and maximize therapeutic efficacy.

Ceftriaxone Sodium Injection 500 mg 1 mL Vials, 10/Pack (Rx)
Ceftriaxone Sodium Injection 500 mg 1 mL Vials, 10/Pack (Rx)
$ 34.95 $ 21.50
🔒 Medical License Required
FAQs for Ceftriaxone Injections – #1 Broad-Spectrum Antibiotic for Potent Infection Control
  • What Is Ceftriaxone Injection Used For?

    Ceftriaxone injection is used to treat a wide range of serious bacterial infections including: Sepsis, pneumonia, meningitis, pelvic inflammatory disease, gonorrhea, and complicated urinary tract infections (UTIs) Pre- and post-surgical infection prevention Severe hospital-acquired infections, and more It is one of the strongest antibiotics prescribed for life-threatening or stubborn infections.

  • How Does Ceftriaxone Work and How Fast?

    Ceftriaxone rapidly kills bacteria by inhibiting cell wall synthesis. After injection, it reaches high blood concentrations within 1-3 hours, offering quick and effective relief—many patients notice improvement within 24-48 hours after their first dose.

  • Can ceftriaxone cause diarrhea?

    Yes, like other antibiotics, ceftriaxone may disrupt gut bacteria, leading to mild to moderate diarrhea. Rarely, it can cause severe Clostridium difficile-associated diarrhea. Taking probiotics with ceftriaxone can help reduce this risk – but consult your doctor first.

  • Can ceftriaxone cause headaches?

    Some patients may experience headaches as a side effect, though this is generally mild and temporary.

  • Can I take fluconazole and ceftriaxone together?

    Yes, fluconazole and ceftriaxone are sometimes prescribed together to treat mixed fungal and bacterial infections. Your healthcare provider will monitor for possible interactions.

  • How long does ceftriaxone injection stay in your system?

    Ceftriaxone has a long half-life (6–9 hours in adults), staying active in your bloodstream for up to 24 hours after each dose, which is why it is often given once daily.

  • What to avoid while taking ceftriaxone?

    Avoid: Alcohol Certain calcium-containing IV solutions (risk of precipitation) Unnecessary antacids or supplements unless advised Discuss all medications and supplements with your doctor to avoid harmful interactions.

  • Should I take probiotics with ceftriaxone?

    Taking probiotics during and after antibiotics is recommended to help restore healthy gut flora and minimize the risk of antibiotic-associated diarrhea.

  • What are the neurological or brain-related side effects?

    Rare side effects on the brain include confusion, seizures, encephalopathy, or hallucinations, especially in patients with kidney impairment or high doses.

  • Does ceftriaxone affect blood pressure

    Alterations in blood pressure are very rare but can occur, especially in susceptible individuals or if given rapidly by IV. Always monitor your blood pressure if at risk.

  • How many days do you take ceftriaxone injection?

    The duration of ceftriaxone therapy depends on the infection type. Courses can last from 3 to 14 days, as determined by your healthcare provider.

  • Why Choose Ceftriaxone Injection?

    Highly effective for serious and resistant bacterial infections Once daily dosing for convenience Clinically proven with a strong safety record Top choice among doctors and hospitals globally

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