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Year-End Sale is Live Now - Up to 50% off
New users? Get 5% off on your first purchase.
Free US shipping over $100

Depo-Medrol for Injection 40 mg, 10 mL x 25/Pack (Rx)

Year End Sale 7%
Original price $ 3,555.95
Current price $ 3,299.00
SKU 00009-0280-52
*Mountainside Medical does not fill personal prescriptions Medical Professional License Required to Unlock Account

How to Order:

Send an email request to: sales@mountainside-medical.com

You will receive instructions on how to create an account along with Rx Ordering Details.

(Note: Acceptable licenses must have Prescriptive Authority in the license issuing state.)

Depo-Medrol Injection 40 mg, 10 mL is an injection prescribed by physicians to provide relief from a wide range of inflammatory processes. It is a corticosteroid proven to be significantly more effective than regular corticosteroid treatments. When administered, Depo-Medrol accelerates the regrowth of muscle tissue, joints, and cartilage. This injection can also reduce redness and swelling caused by a variety of conditions and diseases, such as asthma, rheumatoid arthritis, ulcerative colitis, and numerous allergies. Depo-Medrol has the capacity to essentially relieve a patient from their symptoms overnight, offering an authoritarian method of treatment when other medicinal tactics fail. This leading injection can reduce depressing side effects as well mitigate discomfort almost overnight, proving the efficacity of a Depo-Medrol injection. As long as the administration instructions are followed, the Depo-Medrol Injection ensures excellent results each and every time for healthy, strong muscle and healthy joints.

Benefits for Depo-Medrol for Injection 40 mg, 10 mL

  • Effectively treats inflammatory and immune conditions such as allergic conditions, skin diseases, ulcerative colitis, and arthritis.
  • Reduces swelling and inflammation by decreasing the body's immune response to various diseases and conditions.
  • Offers fast relief from symptoms of inflammation including pain, redness, heat, and swelling.
  • Enhances healing of damaged tissues or organs, such as damaged muscle tissue, inflamed joints, and organ transplant sites.
  • Can be injected directly into the affected area, making it a more unimedical and convenient method of delivering medication.
  • Reduces dependence on oral medications, which often contain unnecessary fillers, dyes, and preservatives which can have adverse reactions on some patients.
  • Easy and painless administration.
  • Long-term relief benefits as it provides sustained relief even after the drug has been eliminated from the body.
  • Its anti-inflammatory properties can improve quality of life for many patients suffering from chronic and severe illnesses.
  • Its high potency allows for the same efficacy across a lower and agreed upon dosage range.

Depo-Medrol (methylprednisolone acetate) for Injection is a sterile injection used to treat pain and swelling that occurs with arthritis and other joint disorders. This medication may also be used to treat various conditions such as blood disorders, severe allergic reactions, certain cancers, eye conditions, skin /intestinal/kidney/lung diseases, and immune system disorders

What Is DEPO-Medrol?
Methylprednisolone is a steroid that prevents the release of substances in the body that cause inflammation. You should not use methylprednisolone if you are allergic to it, or if you have: a fungal infection anywhere in your body.

Brand: Pfizer Injectables
Size: 10 mL x 25 Multi-dose Vials
Strength: 40 mg/mL
NDC: 00009-0280-52
UPC: 300090280529

Depo-Medrol for Injection 40 mg, 10 mL x 25/Pack (Rx)
Depo-Medrol for Injection 40 mg, 10 mL x 25/Pack (Rx)
$ 3,555.95 $ 3,299.00
🔒 Medical License Required
FAQs About Corticosteroid Shots
  • What Is a Corticosteroid Shot?

    A corticosteroid shot (or cortisone injection) is a minimally invasive procedure where synthetic steroid medication is injected directly into joints, tendons, or soft tissues to rapidly reduce inflammation, pain, and swelling. They are commonly used for knee arthritis, shoulder pain, bursitis, tendinitis, gout, and more.

  • Why Do Doctors Not Like to Give Cortisone Shots?

    While highly effective, many doctors limit cortisone or steroid shots because: Overuse can weaken cartilage and soft tissue Too many injections increase risk of joint damage, infection, or systemic side effects Potential for temporary pain flare or “cortisone flare” post-injection Thus, cortisone injections are reserved for the most appropriate cases.

  • What Is the Main Reason for Corticosteroid Use?

    The primary purpose is targeted inflammation control – reducing joint pain, improving mobility, and controlling diseases like rheumatoid arthritis, osteoarthritis, bursitis, and tendinopathies.

  • How Long Does a Cortisone Shot Injection Last?

    Relief can start within 24-72 hours and typically lasts from a few weeks to several months. Duration varies by condition, joint, and individual response.

  • Are Steroid Injections Good for Knee Arthritis?

    Yes, corticosteroid injections are a proven, effective short-term treatment for reducing pain and swelling in moderate to severe knee osteoarthritis. Though not a cure, they improve quality of life and function.

  • What Is an Alternative to a Cortisone Shot?

    Hyaluronic acid injections (viscosupplementation) Physical therapy NSAIDs (nonsteroidal anti-inflammatory drugs) PRP (platelet-rich plasma) injections Lifestyle modification and exercise These can be used alone or in combination depending on severity and patient needs.

  • What Is the Downside of Getting Cortisone Shots?

    Temporary pain or “cortisone flare” after injection Bruising or infection risk Tendon or cartilage weakening if overused Possible increase in blood sugar for diabetics Rarely: facial flushing, allergic reaction, or local fat loss (lipoatrophy)

  • What Is the Difference Between a Cortisone Shot and a Corticosteroid Injection?

    They are the same thing. " Corticosteroid" is the medical term; "cortisone shot" is the common term. Both refer to steroid-based injections used for inflammation.

  • What Is the Success Rate of Corticosteroid Injections?

    Success rates vary, but up to 75–80% of patients experience significant pain relief for weeks or months, especially when the cause is inflammation.

  • Do Steroid Shots Make You Gain Weight?

    While short-term, local injections rarely cause weight gain, repeated or high-dose steroid shots (especially into soft tissue or multiple joints) can increase risk of fluid retention and weight gain. Systemic steroid side effects are uncommon with occasional use.

  • How Many Cortisone Shots Will They Give You?

    Most doctors limit injections to 3–4 times per year per joint to prevent long-term damage. Frequency depends on the joint, diagnosis, and your overall health.

  • How Much Does a Cortisone Shot Cost?

    Corticosteroid injection cost ranges from $100–$300 per shot in the U.S., depending on clinic, location, and insurance coverage.

  • What Should I Avoid After a Cortisone Shot?

    Avoid strenuous activity for 24–48 hours Do not submerge joint in water (baths, pools, hot tubs) for 24 hours Monitor for infection signs (redness, swelling, fever) Follow your doctor’s post-injection instructions

  • What Next if a Cortisone Shot Doesn’t Work?

    Consider alternative injections (hyaluronic acid/PRP/biologics) Physical therapy or alternative medications Consult an orthopedic specialist for surgical options if pain persists

  • What Knee Injection Lasts 3 Years?

    Hyaluronic acid (gel) injections and some new-generation regenerative treatments (like stem cell therapy) may provide longer pain relief (sometimes up to 2–3 years), but results vary.

  • Key Health Benefits of Our Corticosteroid Shots:

    FDA-approved, medical-grade formulations Minimal discomfort with expert placement Rapid, targeted anti-inflammatory response Used for knee and joint pain, arthritis, bursitis, gout, tendonitis Trusted by orthopedic doctors, sports medicine clinics, and pain specialists worldwide

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