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Duraclon Clonidine HCl Injection 100 mcg: Pain management, hypertension relief; supports treatment with precise dosing control.
Duraclon Clonidine HCl Injection 100 mcg: Pain management, hypertension relief; supports treatment with precise dosing control.

Duraclon Clonidine HCl Injection 100 mcg Per mL Preservative Free 10 mL (RX)

by Mylan Institutional
Year End Sale 31%
$ 65.00
$ 45.00
SKU 67457-0218-10
*Mountainside Medical does not fill personal prescriptions Medical Professional License Required to Unlock Account

How to Order:

✔ Send an email request to: sales@mountainside-medical.com

You will receive instructions on how to create an account along with Rx Ordering Details.

(Note: Acceptable licenses must have Prescriptive Authority in the license issuing state.)

Duraclon (Clonidine HCl Injection) 100 mcg is used primarily for the management of severe pain in cancer patients. Administered epidurally, it acts as an adjunct to opioid therapy, enhancing pain relief while potentially reducing the necessary dosage of opioids. Clonidine works by activating alpha-2 adrenergic receptors, which helps modulate the perception of pain. It is used in clinical settings under careful medical supervision to ensure effective pain management and monitor side effects.

Discover the targeted efficacy of Duraclon, a clonidine hydrochloride injection designed for precise management of severe pain in cancer patients who do not respond adequately to opioid therapy alone. Duraclon offers healthcare professionals a supplementary tool, designed for epidural infusion, providing pain relief with a unique pharmacological profile that augments analgesia.

Product Details and Features

Product Name: Duraclon (Clonidine Hydrochloride) Injection
Concentration: 100 mcg/mL
Manufacturer: Mylan Institutional
Dosage Form: Sterile liquid for epidural infusion
Packaging: Provided in securely sealed vials, ensuring sterility and integrity
Indications: Specifically tailored as an adjuvant for the treatment of severe pain in cancer patients, in combination with opioids.
Storage Conditions: Store at controlled room temperature, 20°C to 25°C (68°F to 77°F). Protect from light to maintain efficacy.

Features

Enhanced Pain Management: Acts as a potent adjuvant to heighten the analgesic effects of opioids.
Epidural Delivery: Direct, local administration improves the targeted action to optimize patient comfort.
Quality Manufacture: Produced by Mylan Institutional, assuring consistency, safety, and reliability.

Mechanism of Action

Duraclon contains clonidine, an alpha-2 adrenergic agonist. It works primarily through the stimulation of alpha-2 receptors in the dorsal horn of the spinal cord, which reduces the sympathetic outflow, resulting in decreased nociceptive neurotransmitter release and hyperpolarization of pain-conducting neurons. This modulation of pain signals provides effective analgesic properties when used epidurally, especially when synergistically combined with opioids.

Directions for Use

1. Administration Method: Intended strictly for epidural infusion. Ensure proper aseptic technique during handling.
2. Dilution and Dosage: Dilute with an appropriate epidural infusion solution to achieve a dose-specific combination, as per the detailed instruction of the healthcare provider. Usually administered at a rate specific to patient needs, often requiring careful titration.
3. Monitoring: Close monitoring of the patient's blood pressure and other vitals is essential during administration.

Warnings

  • Appropriate Use: Not recommended for obstetrical, postpartum, or perioperative pain management due to potential hypotension and bradycardia risks.
  • Hemodynamic Stability: May cause significant hypotension; therefore, use with intense caution in patients with severe cardiovascular disorders.
  • CNS Depressants: Coadministration with CNS depressants requires cautious titration and monitoring due to potential potentiation of effects.
  • Withdrawal Concerns: Abrupt discontinuation may induce rebound hypertension; discontinue therapy under medical supervision.

Side Effects

While Duraclon is generally well-managed under medical supervision, potential side effects include:

  • Cardiovascular: Hypotension, bradycardia, and possible orthostatic events.
  • Central Nervous: Sedation, dizziness, headache, dry mouth.
  • Injection Site Reactions: Potential localized reactions due to epidural administration.

Each patient's response can differ; hence, healthcare providers should tailor treatment plans with these considerations in mind. The intent is always to balance effective pain management with minimizing adverse effects.

Using Duraclon (Clonidine HCl) Injection from Mylan Institutional can play a crucial role in providing comprehensive, effective pain relief for eligible patients, enhancing quality of life and patient care outcomes.

Duraclon Clonidine HCl Injection 100 mcg Per mL Preservative Free 10 mL (RX)
Duraclon Clonidine HCl Injection 100 mcg Per mL Preservative Free 10 mL (RX)
$ 65.00 $ 45.00
🔒 Medical License Required
FAQs about Epidural Medications
  • What Medications Are Used in an Epidural?

    The most common medications in an epidural include: Local anesthetics (like lidocaine, bupivacaine, or ropivacaine) Opioids (narcotics) (such as fentanyl, morphine, or sufentanil) Sometimes steroids (like methylprednisolone or triamcinolone) for inflammation and nerve pain, especially in back conditions

  • What Are the Three Types of Epidurals?

    Single-shot epidural: One-time injection of medication into the epidural space for temporary relief. Continuous epidural infusion: Catheter delivers medication over an extended period (common in labor and long surgeries). Combined spinal-epidural (CSE): Combines fast-acting spinal injection with longer-lasting epidural for maximum pain control.

  • Which Two Drugs Are Used in a Standard Epidural?

    A standard epidural typically uses a combination of a local anesthetic (like bupivacaine) and an opioid analgesic (such as fentanyl or morphine) for effective pain relief.

  • What Pain Medication Is Given Instead of an Epidural?

    Alternatives to epidurals for pain control include: IV pain medications (opioids, acetaminophen) Spinal blocks Peripheral nerve blocks Non-opioid analgesics and NSAIDs Consult your healthcare provider for the safest pain management options.

  • What Drug Is in an Epidural for Back Pain?

    Steroids (typically methylprednisolone, triamcinolone, or dexamethasone) combined with a local anesthetic are used in epidural steroid injections for chronic back pain and inflammation.

  • What Drugs Are Used in Epidurals for Labour?

    The most common epidural medications for labor are bupivacaine or ropivacaine mixed with fentanyl for powerful, safe, and rapid pain relief during childbirth.

  • What Is the Most Common Injection for Back Pain?

    Epidural steroid injections with corticosteroids like methylprednisolone or triamcinolone, in combination with a local anesthetic, are the most common and effective treatments for chronic back pain and sciatica.

  • What Kind of Anesthesia Is Used for an Epidural?

    Regional anesthesia is used in an epidural, blocking nerve signals in a targeted part of the body while keeping patients conscious and alert.

  • What Is the Most Common Use for an Epidural?

    The most common use is for labor pain management during childbirth. Epidurals are also frequently used for chronic back pain, spinal stenosis, herniated discs, and sciatica.

  • Do All Epidurals Have Narcotics?

    No, not all epidurals contain narcotics. Some use only local anesthetics, while others combine local anesthetics with opioids for enhanced pain relief.

  • What Pain Meds Do They Give You After Birth?

    Pain relief after birth may include: Oral painkillers (acetaminophen, ibuprofen) Mild opioids when necessary Topical anesthetics Always follow your healthcare provider’s recommendations.

  • What Is the Name of the Injection for Sciatica Pain?

    The standard treatment is an epidural steroid injection (ESI), often using methylprednisolone or triamcinolone.

  • What Is the Best Painkiller for Spinal Stenosis?

    Epidural steroid injections (with corticosteroids and local anesthetics) provide targeted pain relief for spinal stenosis. Oral NSAIDs and neuropathic pain medications can also help.

  • What Is the Best Steroid for Epidural Injection?

    Methylprednisolone acetate is one of the most commonly used and effective steroids in epidural steroid injections.

  • Who Is Not a Good Candidate for an Epidural?

    Contraindications include: Blood clotting disorders Infection at the injection site Certain neurological conditions Severe hypovolemia Allergy to epidural medications Consult your healthcare provider for a thorough evaluation.

  • What Is the Alternative to an Epidural Steroid Injection?

    Alternatives include: Physical therapy Oral anti-inflammatory drugs (NSAIDs) Nerve blocks Radiofrequency ablation Surgery (in severe cases)

  • How Much Does an Epidural Typically Cost?

    The average cost of an epidural ranges from $1,000 to $3,000 depending on insurance, location, and additional procedures. Always check with your provider for exact pricing.

  • Why Choose Our Epidural Medications?

    Clinically-tested, hospital-grade formulations Sterile, safe, and highly effective for rapid pain relief Trusted by anesthesiologists, pain clinics, and hospitals Custom solutions for labor, back pain, spinal stenosis, and more Backed by the latest research in pain management and anesthesia

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