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New users? Get 5% off on your first purchase.
Free US shipping over $100

Diclofenac Sodium and Misoprostol DR 75 mg/200 mcg Tablets 60 Count (RX)

Year End Sale 24%
Original price $ 169.95
Current price $ 129.00
SKU 65162-0438-06
*Mountainside Medical does not fill personal prescriptions Medical Professional License Required to Unlock Account

How to Order:

Send an email request to: sales@mountainside-medical.com

You will receive instructions on how to create an account along with Rx Ordering Details.

(Note: Acceptable licenses must have Prescriptive Authority in the license issuing state.)

Diclofenac Sodium and Misoprostol DR Tablets are used to manage symptoms of arthritis and prevent stomach ulcers in patients taking NSAIDs. Diclofenac, an anti-inflammatory medication, reduces pain, swelling, and joint stiffness, while Misoprostol, a prostaglandin E1 analog, protects the stomach lining by reducing stomach acid, thereby preventing ulcers. Together, they offer a combined treatment for rheumatic conditions requiring anti-inflammatory and gastroprotective therapy under medical guidance.

Introducing Diclofenac Sodium and Misoprostol Delayed Release Tablets by Amneal Pharmaceuticals, a premium pharmaceutical solution for individuals suffering from osteoarthritis and rheumatoid arthritis while reducing the risk of NSAID-induced gastric ulcers. This combination leverages the potent anti-inflammatory and analgesic properties of Diclofenac Sodium with the protective gastric effects of Misoprostol, providing a dual-action therapy for patient convenience and enhanced therapeutic outcomes.

Product Details & Features:

Product Name: Diclofenac Sodium and Misoprostol Delayed Release Tablets
Strength: 75 mg Diclofenac Sodium / 200 mcg Misoprostol
Quantity: 60 Tablets
Manufacturer: Amneal Pharmaceuticals

Features:

  • Dual-Action Formula: Offers pain relief and inflammation reduction from Diclofenac Sodium while protecting the stomach lining with Misoprostol to prevent ulcers.
  • Convenience: Combines two therapeutic agents in one tablet, reducing pill burden for patients.
  • Effective Management: Specifically formulated for patients who require consistent NSAID therapy, helping manage arthritis symptoms while mitigating gastrointestinal side effects.
  • Quality Manufacturing: Produced under strict quality control standards to ensure safety, consistency, and reliability.

Mechanism of Action:

Diclofenac Sodium: An NSAID that works by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, reducing the synthesis of prostaglandins, which results in decreased inflammation and pain relief.
Misoprostol: A prostaglandin E1 analog that not only decreases gastric acid secretion but also increases bicarbonate and mucus production, providing a protective effect on the gastric mucosa to prevent ulceration.

Directions for Use:

Dosage: Take one tablet orally, typically two times a day. Each dose should be taken with food to minimize gastrointestinal irritation. Always follow the specific instructions provided by the prescribing healthcare professional.
Storage: Store the tablets at room temperature away from moisture and heat. Keep them in their original container and out of reach of children.

Warnings:

  • Pregnancy: Contraindicated in pregnant women due to potential for causing uterine contractions and possible miscarriage. Effective contraception is advised during treatment.
  • Cardiovascular Risk: NSAIDs, including Diclofenac, may increase the risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke.
  • Gastrointestinal Risk: While the inclusion of Misoprostol reduces GI risks, serious GI adverse events such as bleeding, ulceration, and perforation can occur.
  • Renal and Hepatic Considerations: Use cautiously in patients with renal or hepatic impairment.

Side Effects:

Common Side Effects:

  • Gastrointestinal: Diarrhea, abdominal pain, indigestion, nausea
  • CNS: Dizziness, headache
  • Skin: Rash

Serious Side Effects (seek medical attention immediately if these occur):

  • Cardiovascular: Chest pain, shortness of breath, weakness on one side of the body
  • Gastrointestinal: Severe stomach pain, bloody stools, or vomit that looks like coffee grounds
  • Allergic Reactions: Hives, difficulty breathing, swelling of the face, lips, tongue, or throat
  • Uterine: Heavy menstrual flow or mid-cycle bleeding

Diclofenac Sodium and Misoprostol Delayed Release Tablets by Amneal Pharmaceuticals represent a sophisticated, dual-action formulation aimed at effectively managing arthritis pain while safeguarding the gastrointestinal tract. It is critical to adhere to the prescribed regimen and report any unusual symptoms to your healthcare provider promptly. Always discuss with your healthcare provider to ensure this medication is suitable for your particular situation.

Diclofenac Sodium and Misoprostol DR 75 mg/200 mcg Tablets 60 Count (RX)
Diclofenac Sodium and Misoprostol DR 75 mg/200 mcg Tablets 60 Count (RX)
$ 169.95 $ 129.00
🔒 Medical License Required
FAQs About Misoprostol Tablets
  • What is Misoprostol?

    Misoprostol is a medication that belongs to a class of drugs called prostaglandin analogs. It mimics the action of prostaglandin E1 in the body.

  • What are Misoprostol Tablets used for

    Misoprostol tablets are a medication with several important uses in medicine, primarily related to the uterus and stomach. The active ingredient is misoprostol, which is a prostaglandin analog.

  • What are the Main Uses of Misoprostol Tablets?

    Prevention of Stomach Ulcers Indication: Often prescribed to prevent gastric ulcers in patients taking long-term non-steroidal anti-inflammatory drugs (NSAIDs), like ibuprofen or aspirin. How it works: By protecting the stomach lining from ulceration caused by NSAID use. Gynecological and Obstetric Uses Inducing Labor: Can be used to ripen the cervix and induce labor in pregnant women, when medically indicated. Medical Abortion: Used in combination with another drug (mifepristone or sometimes methotrexate) to terminate early pregnancies. How it works: Causes contractions of the uterus, leading to expulsion of pregnancy tissue. Treatment of Missed or Incomplete Miscarriage: Helps expel retained pregnancy tissue. Postpartum Hemorrhage: Sometimes used to help control severe bleeding after childbirth by contracting the uterus.

  • How is Misoprostol Taken?

    Tablet forms: Swallowed, dissolved under the tongue (sublingual), or placed inside the cheek (buccal) or vagina (vaginally), depending on medical indication.

  • What are the Common Side Effects?

    Gastrointestinal: Diarrhea, stomach cramps, nausea, vomiting, flatulence. Gynecological: Uterine cramps, vaginal bleeding, headache, chills, fever

  • Why Choose Misoprostol Tablets?

    100% Genuine & Medically Approved – For abortion, postpartum hemorrhage, and gastric ulcer prevention. Fast-Acting Formula – Quick relief for critical health needs. Safe, Discreet Shipping – Delivered to your door with full privacy.

  • What is the use of Misoprostol Tablets in pregnancy?

    Misoprostol is primarily used during pregnancy for medical abortion (early termination of pregnancy), to manage miscarriage (missed abortion), or to induce labor in a medically prescribed setting. It works by causing the uterus to contract and expel its contents. It’s also used to prevent and treat postpartum hemorrhage (excessive bleeding after childbirth).

  • What comes out first after taking Misoprostol?

    Typically, bleeding and tissue will begin to come out first after taking misoprostol. You may notice blood clots and pregnancy tissue passing from the vagina, which indicates that the uterus is being emptied.

  • Do you take 4 or 6 Misoprostol tablets?

    Medical guidelines recommend 4 to 6 Misoprostol tablets (800 mcg to 1200 mcg, usually 200 mcg per tablet) either buccally (in the cheek), vaginally, or sublingually (under the tongue) depending on your doctor's instructions and gestational age. Always follow your licensed healthcare provider’s advice for the correct dosage.

  • How quickly does Misoprostol work?

    Misoprostol usually starts working within 1–4 hours after administration. Expect cramping, bleeding, or passing of tissue as early as 30 minutes, but most women experience effects within a few hours.

  • How long after Misoprostol will I pass?

    You may pass pregnancy tissue within 4–6 hours after taking Misoprostol, but in some cases, it can take up to 24 hours for complete expulsion. If you haven’t experienced expected results, consult your healthcare provider.

  • Can I take Misoprostol at home?

    Yes, the World Health Organization (WHO) and leading medical institutions endorse home use of Misoprostol under medical guidance. Always ensure you are properly prepared, in a safe environment, and have access to medical assistance if needed.

  • How do I know if Misoprostol worked?

    The main signs include heavy bleeding, passing of clots/tissue, and reduction in pregnancy symptoms. A follow-up with ultrasound or clinical exam is needed to confirm a complete abortion or miscarriage.

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