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New users? Get 5% off on your first purchase.
Free US shipping over $100

Monovisc Injection (Sodium Hyaluronate) Prefilled Syringes 88 mg/4mL

Year End Sale 9%
Original price $ 2,195.00
Current price $ 1,999.95
SKU 59676-0820-01
*Mountainside Medical does not fill personal prescriptions Medical Professional License Required to Unlock Account

How to Order:

Send an email request to: sales@mountainside-medical.com

You will receive instructions on how to create an account along with Rx Ordering Details.

(Note: Acceptable licenses must have Prescriptive Authority in the license issuing state.)

Monovisc is a viscoelastic injectable used to treat knee pain from osteoarthritis. It is made of a natural, biodegradable substance that mimics the properties of human cartilage. Monovisc is injected into the knee joint to help relieve pain and improve function.

Benefits for Monovisc Osteoarthritis Knee Pain Treatment

  • Quick and easy to administer – Monovisc prefilled syringes are easy to use, requiring no mixing or preparation prior to injection.
  • Immediate relief – Monovisc is formulated to provide immediate relief from knee pain and can substantially reduce the perceived level of pain immediately upon injection.
  • Long-term relief – Monovisc may provide long-term relief from knee pain by reducing inflammation and providing lubrication for the joint.
  • Minimal side effects – Monovisc carries minimal risks of side effects and is acetylated hyaloruni acid, which is a natural substance in human cartilage.
  • Low cost solution – Monovisc is inexpensive compared to other available treatments for osteoarthritis.

Monovisc (Sodium Hyaluronate) Osteoarthritis Knee Pain Treatment Injection Prefilled Syringes (high molecular weight hyaluronan injection) is a complex sugar used to treat pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy or simple analgesics (e.g., acetaminophen).

Monovisc is a viscous (thick) sterile mixture made from highly purified hyaluronan from bacterial fermentation. Hyaluronan is a natural chemical found in the body. High amounts of hyaluronan are found in the joint tissues and in the fluid that fills the joints.

Monovisc™ is injected into the knee joint and is administered as a single intra-articular injection. Standard intra-articular injection site preparation and precautions should be used. Strict aseptic administration technique must be followed.


Directions For Use:

  • Using an 18 – 20 gauge needle, remove synovial fluid or effusion before injecting Monovisc™. Do not use the same syringe for removing synovial fluid and for injecting Monovisc™; however, the same 18 – 20 gauge needle should be used.
  • Remove the protective rubber cap on the tip of the syringe and securely attach a small gauge needle (18 - 20 gauge) to the tip. Twist the tip cap before pulling it off, as this will minimize product leakage.
  • To ensure a tight seal and prevent leakage during administration, secure the needle tightly while firmly holding the luer hub. Do not over tighten or apply excessive leverage when attaching the needle or removing the needle guard, as this may break the syringe tip.
  • Inject the full 4 mL in one knee only (do not overfill the joint). If treatment is bilateral, a separate syringe should be used for each knee.

Brand: J.O.M. Pharmaceuticals
Size: Single-use 5 mL syringe containing a 4 mL dose
NDC: 59676-0820-01
Type: Prefilled Syringe

Monovisc Injection (Sodium Hyaluronate) Prefilled Syringes 88 mg/4mL
Monovisc Injection (Sodium Hyaluronate) Prefilled Syringes 88 mg/4mL
$ 2,195.00 $ 1,999.95
🔒 Medical License Required
FAQs About Osteoarthritis Knee Pain Injections
  • What injections are given for osteoarthritis knee pain?

    The most popular and effective injections for osteoarthritis knee pain include corticosteroids, hyaluronic acid (gel) injections, and exciting new treatments like platelet-rich plasma (PRP) and stem cell therapy. These options reduce inflammation, lubricate the joint, and stimulate healing, making them preferred choices for those seeking nonsurgical solutions for their knee arthritis pain.

  • What is the best pain relief for osteoarthritis in the knee?

    Top options combine advanced injections with comprehensive pain management, such as hyaluronic acid injections, corticosteroids, and groundbreaking new therapies that go beyond temporary relief. Many patients report significant improvement with these minimally invasive treatments versus oral pain medications.

  • What is the best pain medication for osteoarthritis?

    While NSAIDs (like ibuprofen), acetaminophen, and prescription medications like tramadol are commonly used, many leading rheumatologists now recommend intra-articular knee injections for targeted relief and fewer systemic side effects. Oral options may include duloxetine or new drugs like tanezumab, diclofenac, and peficitinib.

  • Are there any new treatments for knee arthritis?

    Yes! New therapies such as PRP (platelet-rich plasma) injections, stem cell injections, and next-generation hyaluronic acid gels offer impressive results for pain, stiffness, and even cartilage regeneration in osteoarthritic knees.

  • What is the new injection instead of knee replacement?

    Regenerative injections, including PRP and stem cell therapy, are emerging as breakthrough alternatives to knee replacement, aiming to repair damaged tissues and improve knee function, often delaying or avoiding the need for surgery.

  • What are the downsides of gel knee injections?

    While gel injections (viscosupplementation) are generally safe and effective, some patients may experience temporary swelling, infection risk, or variable improvement in pain relief. They may be less effective in severe "bone-on-bone" osteoarthritis.

  • What can you do for unbearable osteoarthritis pain?

    Consider a combination of injections (corticosteroid, hyaluronic acid, or PRP), tailored exercise, physical therapy, weight management, and the latest pain medications. When pain is unmanageable, consult an arthritis specialist for cutting-edge options.

  • What are three of the newest drugs for osteoarthritis pain?

    The latest advancements include tanezumab (an anti-NGF therapy), peficitinib (a JAK inhibitor), and diclofenac gel—offering new avenues for pain control and inflammation reduction.

  • Is gabapentin good for osteoarthritis?

    Gabapentin is generally not a first-line treatment for knee osteoarthritis pain. It may be appropriate for nerve-related pain but less commonly used for typical osteoarthritis symptoms.

  • Can you fix bone-on-bone in knee without surgery?

    While surgery is sometimes required for advanced cases, many patients with bone-on-bone knees experience real improvement with modern injection therapies, especially PRP, stem cells, and high-viscosity gels.

  • Is the injection better than knee surgery?

    For many, injections can delay or avoid the need for knee replacement, providing effective pain relief and improving quality of life without the recovery time and risks of surgery.

  • What knee injection lasts 3 years?

    Clinical studies show some hyaluronic acid injections may provide benefit for up to 2-3 years, especially when combined with other therapies like PRP or regenerative medicine.

  • Can you regrow cartilage in your knees?

    Stem cell and PRP injections hold promise for stimulating cartilage regeneration, though results vary. These are currently the best nonsurgical options for helping restore joint tissue.

  • What is the new breakthrough in osteoarthritis?

    The biggest breakthroughs include biologic injections (PRP, stem cells), targeted anti-NGF drugs like tanezumab, and new high-molecular-weight hyaluronic acid gels for longer-lasting knee pain relief.

  • Is walking good for knee osteoarthritis?

    Absolutely. Moderate walking improves joint mobility, strengthens supporting muscles, and reduces pain when combined with weight management and targeted injections.

  • Is knee osteoarthritis a disability?

    Severe knee osteoarthritis can qualify as a disability, limiting mobility and function. Timely treatment with advanced injections can help prevent progression.

  • What is end stage osteoarthritis?

    End-stage osteoarthritis refers to bone-on-bone contact with complete loss of cartilage, severe pain, loss of motion, and often disability. Injections may still help, but surgery is sometimes considered.

  • What worsens osteoarthritis pain?

    Obesity, inactivity, repetitive stress, poor joint alignment, and skipping treatments are key factors. Early use of injections, exercise, weight management, and anti-inflammatory strategies are crucial.

  • Why Choose Our Osteoarthritis Knee Injections?

    Clinically proven, minimally invasive Targets inflammation, joint lubrication, and cartilage repair Suitable for early to advanced stages, including bone-on-bone cases Effective for those seeking alternatives to knee surgery Trusted by leading orthopedic and rheumatology specialists

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