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Year-End Sale is Live Now - Up to 50% off
New users? Get 5% off on your first purchase.
Free US shipping over $100

Promethegan Promethazine HCL Suppositories 25 mg, 12 Count **Refrigerated (Rx)

Year End Sale 23%
Original price $ 149.95
Current price $ 115.00
SKU 00713-0526-12
*Mountainside Medical does not fill personal prescriptions Medical Professional License Required to Unlock Account

How to Order:

Send an email request to: sales@mountainside-medical.com

You will receive instructions on how to create an account along with Rx Ordering Details.

(Note: Acceptable licenses must have Prescriptive Authority in the license issuing state.)

Promethegan Promethazine HCL Suppositories 25 mg are used to treat nausea, vomiting, and allergies. They are also effective for sedation before and after surgery, motion sickness relief, and as a sleep aid. As an antihistamine, promethazine blocks histamine receptors, helping reduce allergy symptoms like itching and runny nose. This formulation is beneficial for patients who cannot take oral medication due to nausea or vomiting.

Experience relief with Promethegan Promethazine HCL Suppositories 25 mg by Cosette Pharma, expertly formulated to combat nausea, vomiting, and allergy symptoms. Engineered to deliver effective results, Promethegan provides a reliable alternative for those seeking non-oral administration. Each box contains 12 suppositories, designed for convenience and efficacy, making it an essential addition to your healthcare arsenal.

Product Details and Features:

Active Ingredient: Each suppository contains 25 mg of promethazine hydrochloride, an antihistamine with antiemetic properties.
Quantity: Packaged as a 12-count box, offering ample supply for intermittent relief needs.
Form: Rectal suppositories, providing an alternative route of administration for patients with difficulties swallowing or experiencing persistent vomiting.
Quality Assurance: Manufactured under stringent conditions to maintain purity, efficacy, and safety.

Mechanism of Action:

Promethegan works by blocking histamine H1 receptors and the action of acetylcholine in the central nervous system. This dual mechanism not only counteracts allergies and sedates the user but also effectively manages nausea and vomiting by affecting the vestibular system and chemoreceptor trigger zone.

Directions:

  • Dosage: Follow physician’s prescription, generally administered rectally every 4 to 6 hours as needed based on the condition being treated.
  • Administration: Prior to insertion, wash hands thoroughly. Remove the suppository from its packaging, and insert rectally while lying on one side. Retain and relax for at least 15 to 20 minutes after insertion to ensure absorption.
  • Storage: Keep in a cool, dry place, away from light and moisture. Ensure the product is out of children’s reach.

Warnings:

  • Contraindications: Not suitable for use in children under 2 years due to potential respiratory depression risk. Avoid in individuals with known hypersensitivity to promethazine or other phenothiazines.
  • Cautionary Use: Exercise caution in patients with a history of respiratory issues, cardiovascular disease, or seizure disorders.
  • Interactions: Potential interactions with other CNS depressants, anticholinergic drugs, and alcohol. Consult healthcare advisors before combining medications.

Side Effects:

  • Common Side Effects: Drowsiness, dizziness, dry mouth, blurred vision, and constipation. These effects are generally mild and resolve with time.
  • Severe Reactions: Alert medical professionals immediately if experiencing severe drowsiness, confusion, irregular heartbeat, jaundice, or uncontrolled movements.
  • Allergic Reactions: Rash, itching, swelling, severe dizziness, and breathing difficulties require urgent medical attention.

Promethegan Promethazine HCL Suppositories ensure a dependable, alternative solution for those unable to take oral medications. Trust in Cosette Pharma’s commitment to top-quality health products for effective symptom management. Always seek medical consultation for personalized advice and to confirm suitability for individual health needs.

Promethegan Promethazine HCL Suppositories 25 mg, 12 Count **Refrigerated (Rx)
Promethegan Promethazine HCL Suppositories 25 mg, 12 Count **Refrigerated (Rx)
$ 149.95 $ 115.00
🔒 Medical License Required
FAQs About Promethazine
  • What is Promethazine Used For?

    Promethazine is used to treat a wide range of conditions, including: Allergic reactions (such as hay fever, seasonal allergies, hives, and allergic rhinitis) Motion sickness and travel-related nausea Nausea and vomiting from surgery, medications, or other causes Sedation before or after surgery and for sleep disorders Short-term anxiety relief Adjunct in pain management (often used with other medications)

  • What Is the Most Common Use of Promethazine?

    The most common use of Promethazine is preventing and treating nausea and vomiting, as well as providing relief for allergy symptoms. It is also widely used to treat motion sickness and for short-term sedation.

  • Is Promethazine Containing Codeine?

    No, Promethazine does not contain codeine. However, it is sometimes combined with codeine (as in Promethazine with Codeine cough syrup) for prescription cough medications. Promethazine alone is not an opioid and does not have opioid effects.

  • Does Promethazine Make You Sleepy?

    Yes! Promethazine is a strong sedative. Its powerful antihistamine effect blocks histamine in the brain, often resulting in drowsiness or sleepiness. It’s sometimes prescribed specifically for its sleep-inducing qualities.

  • Is Promethazine Used in Mental Health?

    Promethazine is not primarily used for mental health conditions but may be prescribed for short-term anxiety relief or agitation, particularly in acute settings, due to its sedative effects. It is not an approved antipsychotic or antidepressant.

  • Who Should NOT Take Promethazine?

    Promethazine is not safe for everyone. Avoid Promethazine if you: Are a child under 2 years old (risk of severe respiratory depression) Have severe breathing problems (asthma, COPD) Suffer from a history of neuroleptic malignant syndrome Are pregnant or breastfeeding, unless prescribed by your doctor Have liver disease, epilepsy, or a history of severe drug allergies

  • Is Promethazine a Strong Sedative?

    Yes, Promethazine is a strong sedative antihistamine. Its potent effect means caution should be used if tasks require alertness, such as driving or operating machinery.

  • Why is Promethazine a High-Risk Medication?

    Promethazine is considered a high-risk medication due to its strong sedative effect, risk of respiratory depression (especially in children or the elderly), and potential for severe side effects such as neuroleptic malignant syndrome, low blood pressure, and severe allergic reactions.

  • What Drugs Cannot Be Taken with Promethazine?

    Promethazine drug interactions: Avoid combining with: Other sedatives or CNS depressants (alcohol, benzodiazepines, opioids) MAO inhibitors (antidepressants) Certain antipsychotics Medications that cause drowsiness (antihistamines, sleep aids) Medicines that affect heart rhythm Always consult your doctor or pharmacist before combining Promethazine with other drugs.

  • Is Promethazine Opioid-Based? Is it a Controlled Substance?

    No, Promethazine is NOT opioid-based. On its own, it is not a controlled substance. However, Promethazine combined with codeine (a prescription opioid) is a controlled medication.

  • Does Promethazine Make You Feel Good?

    Some users experience a sense of relaxation or mild euphoria due to its sedative effects, but Promethazine is not addictive and does not produce a “high” like opioids or controlled substances.

  • How Fast Does Promethazine Work? How Long Does it Stay in Your System?

    Onset of action: Promethazine typically starts working within 20 minutes to 1 hour after oral administration. Duration: Its effects last 4 to 6 hours, but traces can remain in your system for up to 2 to 3 days.

  • Why Choose Promethazine?

    ✔️ Fast-Acting Allergy & Nausea Relief ✔️ Doctor-Recommended Sedative ✔️ High Safety & Efficacy When Used as Directed ✔️ Trusted Worldwide for Over 70 Years ✔️ Available As Tablets, Syrup, and Injectable

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