Skip to content
+1 (888) 687-4334 | sales@mountainside-medical.com
Year-End Sale is Live Now - Up to 50% off
New users? Get 5% off on your first purchase.
Free US shipping over $100
Year-End Sale is Live Now - Up to 50% off
New users? Get 5% off on your first purchase.
Free US shipping over $100
Login
Click or scroll to zoom
Tap or pinch to zoom
Promethazine HCL for Injection 25 mg vial on a sterile tray, essential for nausea control and allergy relief in medical treatments.
Promethazine HCL for Injection 25 mg vial on a sterile tray, essential for nausea control and allergy relief in medical treatments.

Promethazine HCL for Injection 25 mg Single-Dose Vials 1 mL x 25/Tray (Rx)

by Himka
Sold out
$ 129.95
$ 89.00
SKU 00641-0928-25

Promethazine HCL for Injection is a medication that is used to treat a variety of conditions. It works by blocking the action of histamine in the body. This helps to reduce the symptoms of conditions such as allergies, motion sickness, and nausea.

Himka Promethazine HCL for Injection 25mg Single-Dose 1mL Vials x 25/Tray, Promethazine is the generic equivalent of Phenadoz®, Phenergan® or Promethegan™. It is an antihistamine. This Promethazine comes in a 1mL single-dose vial. Promethazine hydrochloride is a phenothiazine derivative which possesses antihistaminic, sedative, antimotion-sickness, antiemetic, and anticholinergic effects. Promethazine is a competitive H1 receptor antagonist, but does not block the release of histamine. Structural differences from the neuroleptic phenothiazines result in its relative lack (1/10 that of chlorpromazine) of dopamine antagonist properties. Clinical effects are generally apparent within 5 minutes of an intravenous injection and within 20 minutes of an intramuscular injection. Duration of action is four to six hours, although effects may persist up to 12 hours. Promethazine hydrochloride is metabolized in the liver, with the sulfoxides of promethazine and N-desmethylpromethazine being the predominant metabolites appearing in the urine. Following intravenous administration in healthy volunteers, the plasma half-life for promethazine has been reported to range from 9 to 16 hours. The mean plasma half-life for promethazine after intramuscular administration in healthy volunteers has been reported to be 9.8 ± 3.4 hours.

Brand: Himka
NDC: 00641-0928-25
Size: 1 mL Single-dose vial x 25 Per Tray

Promethazine hydrochloride injection is indicated for the following conditions:

  1. Amelioration of allergic reactions to blood or plasma.
  2. In anaphylaxis as an adjunct to epinephrine and other standard measures after the acute symptoms have been controlled.
  3. For other uncomplicated allergic conditions of the immediate type when oral therapy is impossible or contraindicated.
  4. For sedation and relief of apprehension and to produce light sleep from which the patient can be easily aroused.
  5. Active treatment of motion sickness.
  6. Prevention and control of nausea and vomiting associated with certain types of anesthesia and surgery.
  7. As an adjunct to analgesics for the control of postoperative pain.
  8. Preoperative, postoperative, and obstetric (during labor) sedation.
  9. Intravenously in special surgical situations, such as repeated bronchoscopy, ophthalmic surgery, and poor-risk patients, with reduced amounts of meperidine or other narcotic analgesic as an adjunct to anesthesia and analgesia.
Promethazine HCL for Injection 25 mg Single-Dose Vials 1 mL x 25/Tray (Rx)
Promethazine HCL for Injection 25 mg Single-Dose Vials 1 mL x 25/Tray (Rx)
$ 129.95 $ 89.00
FAQs About Promethazine
  • What is Promethazine Used For?

    Promethazine is used to treat a wide range of conditions, including: Allergic reactions (such as hay fever, seasonal allergies, hives, and allergic rhinitis) Motion sickness and travel-related nausea Nausea and vomiting from surgery, medications, or other causes Sedation before or after surgery and for sleep disorders Short-term anxiety relief Adjunct in pain management (often used with other medications)

  • What Is the Most Common Use of Promethazine?

    The most common use of Promethazine is preventing and treating nausea and vomiting, as well as providing relief for allergy symptoms. It is also widely used to treat motion sickness and for short-term sedation.

  • Is Promethazine Containing Codeine?

    No, Promethazine does not contain codeine. However, it is sometimes combined with codeine (as in Promethazine with Codeine cough syrup) for prescription cough medications. Promethazine alone is not an opioid and does not have opioid effects.

  • Does Promethazine Make You Sleepy?

    Yes! Promethazine is a strong sedative. Its powerful antihistamine effect blocks histamine in the brain, often resulting in drowsiness or sleepiness. It’s sometimes prescribed specifically for its sleep-inducing qualities.

  • Is Promethazine Used in Mental Health?

    Promethazine is not primarily used for mental health conditions but may be prescribed for short-term anxiety relief or agitation, particularly in acute settings, due to its sedative effects. It is not an approved antipsychotic or antidepressant.

  • Who Should NOT Take Promethazine?

    Promethazine is not safe for everyone. Avoid Promethazine if you: Are a child under 2 years old (risk of severe respiratory depression) Have severe breathing problems (asthma, COPD) Suffer from a history of neuroleptic malignant syndrome Are pregnant or breastfeeding, unless prescribed by your doctor Have liver disease, epilepsy, or a history of severe drug allergies

  • Is Promethazine a Strong Sedative?

    Yes, Promethazine is a strong sedative antihistamine. Its potent effect means caution should be used if tasks require alertness, such as driving or operating machinery.

  • Why is Promethazine a High-Risk Medication?

    Promethazine is considered a high-risk medication due to its strong sedative effect, risk of respiratory depression (especially in children or the elderly), and potential for severe side effects such as neuroleptic malignant syndrome, low blood pressure, and severe allergic reactions.

  • What Drugs Cannot Be Taken with Promethazine?

    Promethazine drug interactions: Avoid combining with: Other sedatives or CNS depressants (alcohol, benzodiazepines, opioids) MAO inhibitors (antidepressants) Certain antipsychotics Medications that cause drowsiness (antihistamines, sleep aids) Medicines that affect heart rhythm Always consult your doctor or pharmacist before combining Promethazine with other drugs.

  • Is Promethazine Opioid-Based? Is it a Controlled Substance?

    No, Promethazine is NOT opioid-based. On its own, it is not a controlled substance. However, Promethazine combined with codeine (a prescription opioid) is a controlled medication.

  • Does Promethazine Make You Feel Good?

    Some users experience a sense of relaxation or mild euphoria due to its sedative effects, but Promethazine is not addictive and does not produce a “high” like opioids or controlled substances.

  • How Fast Does Promethazine Work? How Long Does it Stay in Your System?

    Onset of action: Promethazine typically starts working within 20 minutes to 1 hour after oral administration. Duration: Its effects last 4 to 6 hours, but traces can remain in your system for up to 2 to 3 days.

  • Why Choose Promethazine?

    ✔️ Fast-Acting Allergy & Nausea Relief ✔️ Doctor-Recommended Sedative ✔️ High Safety & Efficacy When Used as Directed ✔️ Trusted Worldwide for Over 70 Years ✔️ Available As Tablets, Syrup, and Injectable

Search Any Type of Product, Medication, or Alignment