Promethegan Promethazine HCL Suppositories 12.5mg Cosette Pharma, 12 Count

Promethazine is used to treat a wide range of conditions, including: Allergic reactions (such as hay fever, seasonal allergies, hives, and allergic rhinitis) Motion sickness and travel-related nausea Nausea and vomiting from surgery, medications, or other causes Sedation before or after surgery and for sleep disorders Short-term anxiety relief Adjunct in pain management (often used with other medications)

The most common use of Promethazine is preventing and treating nausea and vomiting, as well as providing relief for allergy symptoms. It is also widely used to treat motion sickness and for short-term sedation.

No, Promethazine does not contain codeine. However, it is sometimes combined with codeine (as in Promethazine with Codeine cough syrup) for prescription cough medications. Promethazine alone is not an opioid and does not have opioid effects.

Yes! Promethazine is a strong sedative. Its powerful antihistamine effect blocks histamine in the brain, often resulting in drowsiness or sleepiness. It’s sometimes prescribed specifically for its sleep-inducing qualities.

Promethazine is not primarily used for mental health conditions but may be prescribed for short-term anxiety relief or agitation, particularly in acute settings, due to its sedative effects. It is not an approved antipsychotic or antidepressant.

Promethazine is not safe for everyone. Avoid Promethazine if you: Are a child under 2 years old (risk of severe respiratory depression) Have severe breathing problems (asthma, COPD) Suffer from a history of neuroleptic malignant syndrome Are pregnant or breastfeeding, unless prescribed by your doctor Have liver disease, epilepsy, or a history of severe drug allergies

Yes, Promethazine is a strong sedative antihistamine. Its potent effect means caution should be used if tasks require alertness, such as driving or operating machinery.

Promethazine is considered a high-risk medication due to its strong sedative effect, risk of respiratory depression (especially in children or the elderly), and potential for severe side effects such as neuroleptic malignant syndrome, low blood pressure, and severe allergic reactions.

Promethazine drug interactions: Avoid combining with: Other sedatives or CNS depressants (alcohol, benzodiazepines, opioids) MAO inhibitors (antidepressants) Certain antipsychotics Medications that cause drowsiness (antihistamines, sleep aids) Medicines that affect heart rhythm Always consult your doctor or pharmacist before combining Promethazine with other drugs.

No, Promethazine is NOT opioid-based. On its own, it is not a controlled substance. However, Promethazine combined with codeine (a prescription opioid) is a controlled medication.

Some users experience a sense of relaxation or mild euphoria due to its sedative effects, but Promethazine is not addictive and does not produce a “high” like opioids or controlled substances.

Onset of action: Promethazine typically starts working within 20 minutes to 1 hour after oral administration. Duration: Its effects last 4 to 6 hours, but traces can remain in your system for up to 2 to 3 days.

✔️ Fast-Acting Allergy & Nausea Relief ✔️ Doctor-Recommended Sedative ✔️ High Safety & Efficacy When Used as Directed ✔️ Trusted Worldwide for Over 70 Years ✔️ Available As Tablets, Syrup, and Injectable