Adacel Vaccine (Tdap) Active Booster Immunization for Tetanus, Diphtheria & Pertussis, Sanofi Pasteur **Refrigerated (RX)
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Adacel is a vaccine used as a booster to protect against tetanus, diphtheria, and pertussis (whooping cough). It is approved for adolescents and adults aged 10 to 64 years. For younger children, a different vaccine called DTaP is recommended.
Diseases prevented:
- Tetanus (T): A serious bacterial infection characterized by painful muscle stiffness and spasms, often referred to as "lockjaw."
- Diphtheria (d): A bacterial illness that produces a thick coating in the nose and throat, which can cause difficulty breathing, heart complications, and paralysis.
- Pertussis (ap): Commonly known as whooping cough, this highly contagious respiratory disease leads to intense coughing spells that can disrupt breathing, particularly in infants.
Protect yourself and your community with Adacel Vaccine (Tdap), the leading booster immunization for tetanus, diphtheria, and pertussis (whooping cough). Manufactured by Sanofi Pasteur—a global healthcare leader—Adacel is FDA approved and CDC recommended for teens, adults, and pregnant women to ensure lasting immunity against these three serious diseases.
Adacel Vaccine Syringes (Tdap) by Sanofi Pasteur provide comprehensive booster immunization against Tetanus, Diphtheria, and Pertussis in a convenient, single-dose, preservative-free, pre-filled syringe. Formulated with 5 Lf Tetanus toxoid, 2 Lf reduced Diphtheria toxoid, and 2.5 mcg acellular Pertussis antigen per 0.5 mL dose, Adacel offers reliable protection for adolescents and adults 10 through 64 years of age. Designed for safety, purity, and maximum immunogenicity, Adacel by Sanofi Pasteur is an essential tool in preventing the resurgence of these potentially severe and life-threatening diseases.
Product Highlights & Top Health Benefits
- Triple Protection: Shields against tetanus, diphtheria, and pertussis (Tdap), reducing the risk of severe illness, complications, and transmission.
- Trusted Manufacturer: Developed by Sanofi Pasteur, renowned for vaccine safety, efficacy, and innovation.
- Booster Immunization: Essential for adolescents (11 years and up), adults, and pregnant women to boost waning immunity.
- CDC & FDA Approved: Part of the CDC recommended vaccine schedule for routine and catch-up immunization.
- Maternal Immunization: Safe, effective protection for pregnant women to safeguard newborns from pertussis.
- School & Employment Requirements: Meets immunization regulations for colleges, schools, and healthcare workers.
- Ready-to-Use: Convenient, single-dose intramuscular injection for fast, seamless administration in any healthcare setting.
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What It Is Used For
Adacel (Tdap) Vaccine is indicated for active immunization as a single booster dose for the prevention of:
- Tetanus (lockjaw)
- Diphtheria (a serious bacterial throat infection)
- Pertussis (whooping cough)
Target groups: Adolescents and adults (ages 10–64), as a booster dose following primary vaccination series or when immunity needs refreshing, especially those in contact with infants or at increased risk of exposure.
Details and Features
- Combination Tdap vaccine: Protects against three major infectious diseases
- Pre-filled 0.5 mL single-dose syringes: Ensures dosing accuracy, convenience, and infection control
- Preservative-free formulation: Safe for a broader range of patients
- High immunogenicity: Demonstrated robust antibody responses for all components
- Latex-free syringes: Reduces risk for latex-allergic individuals
- Sanofi Pasteur quality: Renowned leader in vaccine research and safety
- Storage: Store refrigerated at 2° to 8°C (36° to 46°F). Do not freeze.
Dosage
- Recommended Dose: A single 0.5 mL intramuscular (IM) injection
- Administration: Preferably into the deltoid muscle of the upper arm
- Booster Interval: Adacel may be given as a booster dose every 10 years or as recommended by national immunization guidelines.
CDC Guidelines
The CDC’s Advisory Committee on Immunization Practices (ACIP) recommends:
- 1 dose of Tdap (Adacel or Boostrix) for adolescents (11-12 years) and adults who have not previously received Tdap
- Pregnant women: 1 dose during every pregnancy (preferably at 27–36 weeks gestation)
- Booster every 10 years with Td or Tdap for ongoing protection
- Immediate protection for close contacts of infants and healthcare providers
Vaccination is essential for interrupting the transmission of pertussis to vulnerable infants and preventing outbreaks of tetanus and diphtheria.
Mechanism of Action
The Adacel vaccine stimulates the immune system to produce specific antibodies against tetanus, diphtheria, and pertussis toxins and antigens. Upon exposure to these bacteria, the immune system recognizes and neutralizes them, preventing the development of disease or limiting its severity.
Directions
- Inspect vaccine: Ensure the product has not expired and check for particulate matter or discoloration.
- Shake syringe: Gently shake until a uniform, cloudy suspension is observed.
- Prepare injection site: Cleanse with alcohol.
- Administer dose: Inject 0.5 mL intramuscularly, preferably into the deltoid muscle.
- Dispose safely: Sharply and immediately dispose of used syringe in an approved sharps container.
- Record immunization: Update patient’s vaccination record.
Warnings
- Do NOT use in individuals: With a history of severe allergic reaction or anaphylaxis to any component, previous Tdap or other tetanus/diphtheria-containing vaccines.
- Postpone vaccination: During moderate or severe acute illness (wait until recovery).
- Not for use in children <10 years or adults 65+ years (prefer age-appropriate Td/Tdap).
- History of Guillain-Barré syndrome: within 6 weeks after a previous tetanus vaccine—use caution.
- Latex allergy: Check product labeling (most Adacel syringes are latex-free).
- Dosing errors: Do not mix with other vaccines in the same syringe.
Side Effects
Common Side Effects:
- Pain, redness, or swelling at injection site
- Headache, fatigue
- Mild fever, chills
- Body aches, soreness
Less Common but Serious Side Effects:
- Severe allergic reaction (anaphylaxis)
- Neurologic complications (extremely rare, e.g., Guillain-Barré syndrome, brachial neuritis)
- Fainting (more common in adolescents—observe for 15 minutes after injection)
If any severe reaction occurs, seek immediate medical attention.
Protect yourself and your community with Adacel Vaccine Syringes by Sanofi Pasteur—the safe and trusted choice for comprehensive Tdap booster immunization in adolescents and adults. Easy, convenient, preservative-free, and highly effective.