Micafungin Sodium for Injection 100 mg Powder Vial
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Micafungin Sodium for Injection is a potent echinocandin antifungal specifically designed for the treatment of serious fungal infections. This sterile powder, formulated for reconstitution, offers an effective solution for patients in need of robust antifungal therapy.
Uses: Micafungin is commonly used in the treatment of invasive candidiasis, including candidemia, and as a prophylactic measure in patients undergoing hematopoietic stem cell transplantation. It is also effective against esophageal candidiasis.
Dosage:
- Invasive Candidiasis: 100 mg administered once daily via intravenous infusion.
- Esophageal Candidiasis: 150 mg once daily.
- Prophylaxis: 50 mg once daily.
- Dosage should be tailored to the patient's specific condition and response.
CDC Guidelines: While the CDC provides general guidelines for antifungal use, it emphasizes the importance of susceptibility testing and adhering to established treatment protocols. Proper infusion techniques and safety measures should be observed to prevent systemic reactions.
Details and Features:
- Strength: 100 mg per vial
- Formulation: Sterile powder for reconstitution
- Class: Echinocandin antifungal
- Broad Spectrum: Effective against a range of Candida species
- IV Administration: Allows for precise dosing in severe cases
Mechanism of Action: Micafungin works by inhibiting the synthesis of β-1,3-D-glucan, an essential component of the fungal cell wall. This disrupts cell wall integrity, leading to cell lysis and death of the fungal organism.
Directions for Use:
- Reconstitute the powder with sterile water following aseptic technique.
- Administer via intravenous infusion over approximately one hour.
- Follow healthcare provider instructions and institutional protocols for dosing and administration.
Warnings:
- Monitor liver function; micafungin may cause hepatic impairment.
- Use with caution in patients with renal or hepatic dysfunction.
- Adjust dose according to patient’s therapeutic response and condition.
Side Effects: Common side effects include:
- Rash
- Nausea
- Vomiting
- Diarrhea
- Elevated liver enzymes In the event of severe adverse effects, discontinue use and seek medical attention.
Micafungin Sodium for Injection by Hikma delivers reliable antifungal efficacy for the management of critical fungal infections, ensuring optimal patient care with targeted therapeutic action.