Sodium Tetradecyl Sulfate Injection 3%, Multiple-Dose Vials 2 mL x 5/Box
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Sodium tetradecyl sulfate 3% injection is a sterile, nonpyrogenic sclerosing agent used to treat small, uncomplicated varicose veins in the legs as well as certain vascular malformations. It is marketed under the brand name Sotradecol, among others.
How it works Sodium tetradecyl sulfate (STS) is an anionic surfactant, similar to soap, that is injected directly into the affected vein. Its action involves three main steps:
- Endothelial damage: STS injures the inner lining (endothelium) of the vein, triggering inflammation.
- Thrombus formation: The inflammation causes a blood clot (thrombus) to form and occlude the treated vein.
- Sclerosis: The blocked vein gradually turns into fibrous tissue, is reabsorbed by the body, and eventually disappears.
Indications and usage The 3% concentration is typically used for treating larger varicose veins, while a lower 1% solution is reserved for smaller veins.
Sodium Tetradecyl Sulfate Injection 3% is used in sclerotherapy to treat varicose veins and spider veins. It acts as a sclerosing agent by irritating the lining of veins, causing them to collapse and eventually be reabsorbed by the body. This treatment is commonly used for larger varicose veins. By closing these veins, symptoms such as pain, swelling, and skin irritation can be reduced, and the appearance of the veins is improved. The procedure is minimally invasive and is often done in an outpatient setting.
Sodium Tetradecyl Sulfate Injection 3% is a sclerosing agent used for the treatment of small varicose veins in the lower extremities. This professional-grade medication is designed to provide effective vein sclerotherapy, helping to reduce the appearance and symptoms of varicose veins.
Uses: Indicated for the treatment of small uncomplicated varicose veins, such as those associated with superficial venous reflux.
Dosage:
- The recommended dosage depends on the size and type of the vein. Typically, 0.1 to 0.3 mL is injected per vein.
- Maximum dosage per session is usually up to 10 mL.
CDC Guidelines: While the CDC provides guidelines on managing chronic venous disorders, specific treatment plans should be directed by a healthcare professional. Proper aseptic techniques are critical during administration to prevent infection.
Details and Features:
- Concentration: 30 mg/mL in 2 mL multiple-dose vials.
- Quantity: 5 vials per box.
- Strength: 60 mg / 2 mL.
- Storage: Store at controlled room temperature, 20° to 25°C (68° to 77°F).
Mechanism of Action: Sodium Tetradecyl Sulfate works by irritating the vein lining, leading to sclerosis (vein closure). This results in the reabsorption of the treated vein by the body over time.
Directions:
- Administer by a trained healthcare professional under aseptic conditions.
- Select the appropriate dosage based on the target vein.
- Inject slowly into the varicose vein using suitable sclerotherapy techniques.
- Compress the treated area where necessary.
Warnings:
- For professional use only; not for self-administration.
- Contraindicated in patients with a history of allergic reactions to Sodium Tetradecyl Sulfate.
- Avoid in patients with acute infections, uncontrolled diabetes, or a known coagulation disorder.
- Not recommended for pregnant or breastfeeding women unless absolutely necessary.
Side Effects:
- Common: Mild pain or irritation at the injection site, localized swelling or bruising.
- Severe: Allergic reactions, systemic embolism, tissue necrosis, deep vein thrombosis.
- Report any severe side effects to a healthcare provider immediately.
Sodium Tetradecyl Sulfate Injection 3% by Hikma Injectables is a trusted solution for sclerotherapy of small varicose veins, offering reliable results when administered by healthcare professionals.
