What Is a Corticosteroid Shot?

A corticosteroid shot (or cortisone injection) is a minimally invasive procedure where synthetic steroid medication is injected directly into joints, tendons, or soft tissues to rapidly reduce inflammation, pain, and swelling. They are commonly used for knee arthritis, shoulder pain, bursitis, tendinitis, gout, and more.

Why Do Doctors Not Like to Give Cortisone Shots?

While highly effective, many doctors limit cortisone or steroid shots because: Overuse can weaken cartilage and soft tissue Too many injections increase risk of joint damage, infection, or systemic side effects Potential for temporary pain flare or “cortisone flare” post-injection Thus, cortisone injections are reserved for the most appropriate cases.

What Is the Main Reason for Corticosteroid Use?

The primary purpose is targeted inflammation control – reducing joint pain, improving mobility, and controlling diseases like rheumatoid arthritis, osteoarthritis, bursitis, and tendinopathies.

How Long Does a Cortisone Shot Injection Last?

Relief can start within 24-72 hours and typically lasts from a few weeks to several months. Duration varies by condition, joint, and individual response.

Are Steroid Injections Good for Knee Arthritis?

Yes, corticosteroid injections are a proven, effective short-term treatment for reducing pain and swelling in moderate to severe knee osteoarthritis. Though not a cure, they improve quality of life and function.

What Is an Alternative to a Cortisone Shot?

Hyaluronic acid injections (viscosupplementation) Physical therapy NSAIDs (nonsteroidal anti-inflammatory drugs) PRP (platelet-rich plasma) injections Lifestyle modification and exercise These can be used alone or in combination depending on severity and patient needs.

What Is the Downside of Getting Cortisone Shots?

Temporary pain or “cortisone flare” after injection Bruising or infection risk Tendon or cartilage weakening if overused Possible increase in blood sugar for diabetics Rarely: facial flushing, allergic reaction, or local fat loss (lipoatrophy)

What Is the Difference Between a Cortisone Shot and a Corticosteroid Injection?

They are the same thing. " Corticosteroid" is the medical term; "cortisone shot" is the common term. Both refer to steroid-based injections used for inflammation.

What Is the Success Rate of Corticosteroid Injections?

Success rates vary, but up to 75–80% of patients experience significant pain relief for weeks or months, especially when the cause is inflammation.

Do Steroid Shots Make You Gain Weight?

While short-term, local injections rarely cause weight gain, repeated or high-dose steroid shots (especially into soft tissue or multiple joints) can increase risk of fluid retention and weight gain. Systemic steroid side effects are uncommon with occasional use.

How Many Cortisone Shots Will They Give You?

Most doctors limit injections to 3–4 times per year per joint to prevent long-term damage. Frequency depends on the joint, diagnosis, and your overall health.

How Much Does a Cortisone Shot Cost?

Corticosteroid injection cost ranges from $100–$300 per shot in the U.S., depending on clinic, location, and insurance coverage.

What Should I Avoid After a Cortisone Shot?

Avoid strenuous activity for 24–48 hours Do not submerge joint in water (baths, pools, hot tubs) for 24 hours Monitor for infection signs (redness, swelling, fever) Follow your doctor’s post-injection instructions

What Next if a Cortisone Shot Doesn’t Work?

Consider alternative injections (hyaluronic acid/PRP/biologics) Physical therapy or alternative medications Consult an orthopedic specialist for surgical options if pain persists

What Knee Injection Lasts 3 Years?

Hyaluronic acid (gel) injections and some new-generation regenerative treatments (like stem cell therapy) may provide longer pain relief (sometimes up to 2–3 years), but results vary.

Key Health Benefits of Our Corticosteroid Shots:

FDA-approved, medical-grade formulations Minimal discomfort with expert placement Rapid, targeted anti-inflammatory response Used for knee and joint pain, arthritis, bursitis, gout, tendonitis Trusted by orthopedic doctors, sports medicine clinics, and pain specialists worldwide

Corticosteroid Shots

Experience fast, effective relief with Corticosteroid Shots, trusted for reducing inflammation, pain, and swelling in joints, muscles, and soft tissues. Ideal for treating arthritis, allergies, asthma, and autoimmune conditions, these injections deliver targeted therapy for long-lasting symptom management. Perfect for pain relief, mobility improvement, and chronic condition support, our corticosteroid shots ensure rapid results, improve quality of life, and promote optimal patient health and recovery.

Show
24
36
48

View as

Sale 35%

Original price $ 215.95

Current price $ 139.95

Depo-Medrol Injection 40 mg Vial 10 mL by Hospira Pfizer (Rx)
Pfizer Injectables

1 review

Depo-Medrol Injection 40 mg is used to treat a variety of inflammatory and allergic conditions. It contains methylprednisolone acetate, a corticost...
View full details
Sale 20%

Original price $ 499.95

Current price $ 399.95

Depo-Medrol for Injection 40 mg, 1 mL x 25/Pack (Rx)
Pfizer Injectables

1 review

Depo-Medrol for Injection 40 mg, 1 mL is an anti-inflammatory medication used to relieve pain, swelling, redness, stiffness, and other symptoms of ...
View full details
Sale 34%

Original price $ 45.00

Current price $ 29.55

Depo-Medrol Methylprednisolone Acetate 80 mg for Injection 1 mL Vial (Rx)
Pfizer Injectables

No reviews

Depo-Medrol Methylprednisolone Acetate 80 mg is a corticosteroid injection used to alleviate inflammation and manage a variety of conditions, inclu...
View full details
Sale 22%

Original price $ 299.95

Current price $ 235.00

Solu-Medrol Injection 40 mg Single-dose Act-O-Vial System Vials 25/Tray by Pfzier (RX)
Pfizer Injectables

No reviews

Solu-Medrol Injection 40 mg is a brand name for an injectable form of methylprednisolone sodium succinate, which is a synthetic corticosteroid (ste...
View full details
Sale 23%

Original price $ 149.95

Current price $ 116.00

Solu-Cortef for Injection 500 mg Single Dose Vial 4 mL by Pfizer (RX)
Pfizer Injectables

No reviews

Solu-Cortef for Injection 500 mg is a corticosteroid used to treat inflammation and immune response related to conditions such as adrenal insuffici...
View full details
Sale 7%

Original price $ 3,555.95

Current price $ 3,299.00

Depo-Medrol for Injection 40 mg, 10 mL x 25/Pack (Rx)
Pfizer Injectables

No reviews

Depo-Medrol Injection 40 mg, 10 mL is an injection prescribed by physicians to provide relief from a wide range of inflammatory processes. It is a ...
View full details

Filters

Corticosteroid Shots

Depo-Medrol Injection 40 mg Vial 10 mL by Hospira Pfizer (Rx)

Depo-Medrol for Injection 40 mg, 1 mL x 25/Pack (Rx)

Depo-Medrol Methylprednisolone Acetate 80 mg for Injection 1 mL Vial (Rx)

Solu-Medrol Injection 40 mg Single-dose Act-O-Vial System Vials 25/Tray by Pfzier (RX)

Solu-Cortef for Injection 500 mg Single Dose Vial 4 mL by Pfizer (RX)

Depo-Medrol for Injection 40 mg, 10 mL x 25/Pack (Rx)

Added to your cart: