Amphotericin B (AmpB) USP (Oral Grade) For Compounding (API) (Rx)

Amphotericin B (AmphB) USP (Oral Grade) active pharmaceutical ingredient (API) is a broad-spectrum antifungal agent derived from Streptomyces nodosus. It is a polyene macrolide antibiotic that works by binding to the fungal cell membrane and disrupting its integrity, ultimately leading to cell death.

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This particular form of Amphotericin B has been specifically formulated for oral administration, making it suitable for treating systemic fungal infections in the mouth and intestines. It is also used in the treatment of invasive fungal infections, such as candidiasis, aspergillosis, and cryptococcosis.

Amphotericin B is considered a first-line treatment for severe or life-threatening fungal infections and is commonly used in combination with other antifungal medications. It is available as a powder for reconstitution into an oral suspension, allowing for easy and convenient administration.

As an API, Amphotericin B (AmphB) USP (Oral Grade) may be used in the production of various pharmaceutical products, such as capsules, tablets, and oral suspensions, for the treatment of fungal infections.