Mastisol Liquid Adhesive 0.67 mL – Medical-Grade Skin Glue for Secure Wound Care

Mastisol® Liquid Adhesive is a medical-grade, sterile liquid skin adhesive designed to secure dressings, bandages, tapes, and medical devices on intact skin. This latex-free, non-irritating formula forms a strong, waterproof barrier that holds dressings and tubing firmly in place even on moist or perspiring skin. In healthcare settings, Mastisol is widely used to enhance tape adhesion and prevent accidental dressing displacement – reducing device dislodgements and infection risk by creating a lasting occlusive skin barrier. According to the manufacturer, “Mastisol is a liquid medical adhesive used to secure dressings, tapes, and certain medical devices over an extended period of time”. It is CHG-compatible (works over chlorhexidine-prepped skin) and non-staining, so it won’t discolor skin or sharps dressings. In short, Mastisol is a top-performing wound-care adhesive for hospitals, clinics, and first-aid use that improves patient safety and dressing retention.

Key Features & Benefits: Mastisol 0.67 mL comes as a sterile, single-use glass vial with a fiber-tipped applicator. Each vial contains a quick-dry clear solution of natural resins (gum mastic and liquid styrax) in a denatured alcohol base with methyl salicylate. Once applied in a thin line, the adhesive dries in about 20–30 seconds to form a tough, insoluble film. Because it is non-water soluble and provides a moisture-proof seal, Mastisol maintains its grip even on sweating patients. This long-lasting bond means fewer dressing changes and less risk of IV or tube dislodgment. Notably, Mastisol is latex-free and hypoallergenic, with a low incidence of sensitivity reactions. Medical staff appreciate that Mastisol is “compatible with chlorhexidine gluconate (CHG)”  and does not contain natural rubber, so it won’t cause latex allergies. Other highlights include its clear, non-staining formula and high tensile strength that outperforms ordinary medical tape or collodion.

• Medical-Grade Skin Adhesive: Improves tape & dressing adhesion; secures medical device dressings and closure strips.
• Sterile Single-Use Vial: Each 0.67 mL glass vial includes a fiber-tip swab applicator in a tamper-proof blister.
• Waterproof Barrier: Non-water-soluble, fast-drying film that holds on moist or highly mobile skin.
• Latex-Free & Hypoallergenic: Gentle on skin with low irritation risk.
• Long-Lasting Security: Reduces dressing displacement and device dislodgement, helping prevent infections.
• Compatible with CHG: Safe to use over chlorhexidine skin prep commonly used in hospitals.

Uses and Applications

Mastisol 0.67 mL is ideal for a wide range of clinical and first-aid applications where dressings must stay put. Health professionals use it wherever secure wound dressings and device fixation are needed. Key uses include:

• Wound Care & Dressings: Securing gauze, bandages, Steri-Strips or surgical dressings on cuts, abrasions and minor wounds. Improves adherence of medical tapes and adhesive bandages.
• Tape/Drape Securement: Reinforces surgical tapes, drapes, and ECG electrode adhesives – crucial in operating rooms and emergency care.
• Vascular Access (IV Lines & Catheters): Anchors IV catheters, PICC lines, infusion sets and dialysis needles to skin, reducing risk of line dislodgment.
• Airway & Nutrition Tubes: Holds endotracheal tubes, tracheostomy tubes, and nasogastric/feeding tubes firmly, preventing unplanned extubation or NG tube movement.
• Chest Drains & Drips: Secures chest tube dressings, drains, and IV tubing in critical care (ICU/ER) settings.
• Ostomy Appliances: Keeps ostomy pouches (colostomy/ileostomy) and other pouching systems sealed against leaks and lifting.
• Pediatric & Geriatric Care: Safe for sensitive or fragile skin – often used in NICU, pediatric wards, or with elderly patients who need gentle adhesive solutions.
• Emergency & Field Medicine: Quick-setting hold makes it useful in ambulance/EMS kits and first-aid supplies for trauma dressings.

Health clinics and hospitals use Mastisol across departments – Operating Room, ICU, ED, Oncology, Respiratory Therapy, Pediatrics, and more. It’s also helpful for specialty uses like securing glucose monitor patches (insulin pumps/CGM devices) or pain-transducer pads, thanks to its hypoallergenic, strong-bond formula.

Specifications

• Product: Mastisol® Liquid Adhesive, health-care grade skin adhesive (Brand of Ferndale Laboratories / Eloquest Healthcare).
• Volume: 0.67 mL (approximately 2/3 cc) per vial.
• Packaging: Sterile, single-use glass or plastic vial with fiber gel tip. Packaged in a blister card; typically 48 vials per box.
• Ingredients: Contains gum mastic, liquid styrax (resins), special denatured alcohol (SD 23), and methyl salicylate. (Alcohol solvent evaporates after drying.)
• Formula: Clear, colorless liquid; odor of alcohol. Dries to form a transparent film. Water-proof (non-water-soluble) after drying.
• Key Properties: CHG-compatible; Latex-free; Non-irritating and non-staining.
• Sterility: Heat-sterilized single-dose vials (aseptic packaging).
• Storage: Store at room temperature. Combustible (contains flammable solvent). Keep away from heat/flame.
• Regulatory: Not made with natural rubber latex (safe for latex-allergy patients). (HCPCS code A6250).
• Coverage: Often HSA/FSA-eligible (paid with health savings accounts).

How to Use

Proper application is quick and easy. Follow these steps to ensure maximum adhesion:

1. Crack the Vial: Place the sealed vial in its blister card on a hard surface, label down. Press firmly to break the inner glass ampoule (you will hear a snap). This releases the Mastisol into the vial’s reservoir.
2. Peel and Remove: Peel back the foil cover of the blister card. Using aseptic technique, remove the vial from the pack. (Hold it upright to avoid spilling.)
3. Apply Adhesive: Invert the vial over the target skin area. Gently squeeze to dispense a thin ½-inch wide line or dot of Mastisol onto clean, dry skin. Apply the adhesive around the border of where the dressing or tape will go, avoiding making a thick glob. (For a secure catheter dressing, trace around the IV site, for example.)
4. Allow to Dry: Wait about 20–30 seconds for Mastisol to dry and tacky. (The alcohol solvent evaporates, leaving a clear sticky film.) Do not disturb the film during drying to ensure full bond strength.
5. Dress and Secure: Apply the dressing, tape, or medical device so that its edges contact the adhesive. Press firmly to embed edges into the Mastisol film. Smooth out any wrinkles for full contact.
6. Removal (if needed): When removing, gently peel away the tape or dressing. A medical adhesive remover (e.g. Detachol®) can ease removal if needed, protecting skin integrity.

For best results, always apply Mastisol to intact, clean skin. Let the adhesive fully dry before subjecting the area to moisture or friction. In sum, Mastisol’s “crack, peel, apply, dress” routine ensures reliable adhesion: crack the vial, peel it open, apply Mastisol to the skin, wait 30 sec, and then press on the dressing.

By following these steps, healthcare providers achieve secure, durable fixation of dressings and devices. Mastisol’s strong tack means fewer unexpected dressing changes and enhanced patient comfort during wound care and IV therapy.