Spironolactone USP/EP for Compounding (API) is an active pharmaceutical ingredient used primarily in the formulation of medications for treating conditions related to fluid retention and hormonal imbalances. As a potassium-sparing diuretic, spironolactone is commonly prescribed to manage edema associated with congestive heart failure, liver cirrhosis, and nephrotic syndrome. It is also used in the treatment of hypertension (high blood pressure) and primary hyperaldosteronism. Additionally, spironolactone is utilized in the management of hormonal disorders such as polycystic ovary syndrome (PCOS) and certain cases of acne due to its anti-androgen properties, which help reduce excessive facial hair and acne in women. Compounding allows for customized dosage forms tailored to the specific needs of patients.
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Spironolactone USP active pharmaceutical ingredient (API) is a synthetic steroidal medication used primarily as a diuretic and to treat conditions such as high blood pressure, heart failure, and swelling caused by liver disease. It works by blocking the actions of a hormone called aldosterone, which regulates salt and water balance in the body. Spironolactone is a selective antagonist of the aldosterone receptor and is considered a potassium-sparing diuretic, meaning it can increase the excretion of water and sodium from the body while also preventing the loss of potassium. It is available as a tablet or injection and is typically used in combination with other medications to treat various conditions. Spironolactone USP is a regulated and standardized form of spironolactone that meets the quality and purity standards set by the United States Pharmacopeia.Â
Spironolactone USP is a prescription medication that is used to treat conditions that cause the body to retain too much salt and water. It is also sometimes used to treat high blood pressure and heart failure. When used for compounding, it is often used in topical formulations for treating acne or hirsutism (excessive hair growth), and in oral formulations for treating polycystic ovary syndrome (PCOS) or hormonal imbalances.
CAS Number: 52-01-7
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