Medications used to Treat Fibromyalgia (fibrositis) syndrome. The exact cause of fibromyalgia is unknown, but it has been linked to depression, anxiety, other pain problems, and emotional stress. Fibromyalgia affects as many as 5 million Americans ages 18 and older. Most people with fibromyalgia are women (about 80 - 90 percent). However, men and children also can have the disorder. Most people are diagnosed during middle age. People with fibromyalgia also have "tender points" throughout their bodies. Tender points are specific places on the neck, shoulders, back, hips, arms, and legs that hurt when pressure is put on them. Three medicines have been approved by the U.S. Food and Drug Administration (FDA) to treat fibromyalgia. These are pregabalin (Lyrica), duloxetine (Cymbalta), and milnacipran (Savella). There is also a Topical pain relief gel called Mountain Ice Pain Gel that is also FDA and has been showing some amazing results on relieving pain associated with fibromyalgia. Your doctor may also suggest non-narcotic pain relievers, low-dose antidepressants, or other classes of medications that might help improve certain symptoms.