MOTS-c Injection 10 mg - Mitochondrial-Derived Peptide with 16 Amino Acid

MOTS-c is a mitochondrial-derived peptide being studied for its effects on metabolism, insulin sensitivity, and the body’s response to physical and metabolic stress. Its name stands for mitochondrial open reading frame of the 12S rRNA type-c.

The body naturally produces MOTS-c. Products sold as “MOTS-c injections” contain a synthetic version intended to resemble that naturally occurring peptide. However, a naturally occurring substance is not automatically safe or effective when injected.

How does MOTS-c work?

MOTS-c acts as a signaling peptide rather than simply supplying fuel or “boosting mitochondria.”

Research suggests it can:

• Influence AMPK signaling: AMPK is an important cellular energy sensor involved in glucose uptake, fat metabolism, and energy balance.
• Affect folate and purine metabolism: Changes in these pathways appear to contribute to its metabolic signaling effects.
• Help regulate stress-response genes: Under metabolic stress, MOTS-c can move into the cell nucleus and influence gene expression.
• Support communication between mitochondria and the nucleus: This may help coordinate how cells respond to changing energy demands.

These mechanisms explain the scientific interest, but a plausible biological mechanism does not establish that an injection is clinically beneficial.

Which amino acids is MOTS-c made of?

MOTS-c contains 16 amino acid residues, arranged in this specific order:

Met–Arg–Trp–Gln–Glu–Met–Gly–Tyr–Ile–Phe–Tyr–Pro–Arg–Lys–Leu–Arg

Its one-letter sequence is:

MRWQEMGYIFYPRKLR

The sequence is associated with a short open reading frame within the mitochondrial 12S ribosomal RNA gene. An injectable product may also contain diluents or other ingredients; these are formulation-specific and are not part of the peptide itself.