Bacteriostatic Sodium Chloride 0.9% Saline Injection Multiple Dose 30 ml x 25/Pack (Rx)

Bacteriostatic Sodium Chloride 0.9% Injection is a sterile normal saline solution (0.9% sodium chloride in water) that contains a small amount of a bacteriostatic preservative. In most formulations, the preservative is benzyl alcohol (0.9% benzyl alcohol per mL), which inhibits the growth of bacteria. The presence of this preservative keeps the solution sterile between uses, allowing the product to be packaged in a multiple-dose vial for repeated withdrawals without contamination. In other words, “bacteriostatic” means it prevents bacteria from growing, so the same vial of saline can be used multiple times (within its recommended timeframe) instead of being single-use.

Composition and Properties

This injection is essentially 0.9% sodium chloride (NaCl) dissolved in sterile water—with 9 mg of sodium chloride per milliliter, making it isotonic with blood and tissues. The isotonic nature means it has the same salt concentration as normal body fluids, so it won’t cause cells to shrink or swell when injected. In addition to salt, each milliliter contains about 9 mg of benzyl alcohol (0.9%) as the bacteriostatic agent. The benzyl alcohol does not treat infection, but its job is to keep the solution sterile by inhibiting bacterial growth if the vial is used more than once. The solution is labeled “nonpyrogenic”, meaning it’s free from substances that cause fever, and it’s intended for parenteral use (injection). Because it’s a USP-grade preparation, it meets quality standards for purity and sterility required for injectable solutions.

Intended Use (Diluent for Medications)

Bacteriostatic 0.9% Sodium Chloride Injection is not a medication on its own – it’s a diluent or solvent used to prepare other drugs for injection. According to its labeling, this solution is indicated only for diluting or dissolving drugs for injection (whether intravenous (IV), intramuscular (IM), or subcutaneous (SC)). For example, if you have a vial of powdered medication that needs to be injected, you might add this bacteriostatic saline to reconstitute (dissolve) the powder into a liquid form for injection. Similarly, it can be used to dilute concentrated drugs to the proper strength before injecting them. Healthcare providers also sometimes use sterile saline solutions to flush IV lines or injection sites, but in many cases preservative-free saline is preferred for flushing (especially in sensitive patients). The key point is that Bacteriostatic Sodium Chloride 0.9% Injection provides a sterile salt-water medium for mixing medications, and its bacteriostatic property allows the vial to be used for multiple doses or multiple patients (with proper sterile technique) instead of being discarded after a single use.

Uses

• Diluting or dissolving drugs for injection.
• Flushing IV lines (less common).
• Used in situations when multiple-dose vials are required, because the bacteriostatic agent prevents bacterial contamination during repeated entries.

Order Bacteriostatic Sodium Chloride 0.9% Injection 30 mL x 25/Pack by Pfizer Today!

NDC: 0409-1966-07 | UPC: 304091966024 Fast Shipping | Bulk Pack | FDA-Approved | Trusted by Hospitals Everywhere

Provide your clinical team with the safest, most reliable multi-dose injectable saline available on the market—choose Pfizer Bacteriostatic Sodium Chloride for every reconstitution, dilution, and flush need.

Uses & Applications

Bacteriostatic Sodium Chloride 0.9% Injection is indicated for:

• Reconstitution and dilution of injectable medications: Antibiotics, biologics, hormones, and other drugs requiring sterile saline
• Flushing IV lines and catheters: To prevent blockage and maintain line patency
• Sterile wound irrigation in clinical settings
• Intravenous, intramuscular (IM), or subcutaneous (SC) injection as a vehicle for compatible drugs
• Preparing syringes for allergy shots, HRT, botulinum toxin, and other compounded injections
• Basic clinical saline needs where repeated withdrawals from a single vial are necessary

Benefits & Features

• USP-Grade 0.9% Sodium Chloride: Hospital-quality, isotonic, and safe for injection
• Bacteriostatic (0.9% benzyl alcohol): Antimicrobial preservative prolongs vial sterility, prevents contamination from multiple punctures
• Multiple Dose 30 mL Vials: Enables efficient, cost-effective saline usage for multiple patients or preparations
• Bulk 25/Pack: Ideal for clinics, hospitals, and high-volume outpatient facilities
• Pyrogen-free and latex-free: Reduces risks of fever or allergic reactions
• Easy-to-Use Packaging: Flip-top vials allow for convenient withdrawals by syringe
• Pfizer Injectables Brand: Trusted globally for pharmacy, medical, and laboratory supply

Instructions on How to Use

1. Inspect vial: Ensure solution is clear with no particulates or discolouration.
2. Sanitise vial stopper: Wipe with alcohol before each needle entry.
3. Withdraw desired amount: Use a sterile syringe and needle for each access.
4. Use strictly aseptic technique to avoid contamination.
5. Inject, reconstitute, or flush as directed by accompanying medication, protocol, or provider’s instructions.
6. Discard remaining solution 28 days after initial entry or sooner if contamination is suspected.

Not for direct IV infusion without proper mixing with medications unless specifically indicated.

Dosage and Administration

• For reconstitution/dilution:
  • Follow medication-specific guidelines; use only the required volume for safe, effective mixing.
• For IV/IM/SC Injection as vehicle:
  • Use as recommended by the medication manufacturer or the physician's protocol.
• For flushing catheters or IV lines:
  • Typically 2–5 mL as needed, using sterile technique.
• Wound irrigation:
  • Use per facility standard procedures.

NEVER use bacteriostatic saline in neonates or infants due to risk of benzyl alcohol toxicity (“gasping syndrome”).

Drug Interactions

• No known direct drug-drug interactions with sodium chloride.
• Check all medication inserts for compatibility before reconstitution or dilution.
• Some drugs may precipitate or lose efficacy in saline;, always consult pharmacist or medication guide.

Side Effects & Warnings

Common Side Effects:

• Mild injection site irritation, swelling, or redness, especially if injected IM/SC.
• Rarely, local allergic or site reactions due to benzyl alcohol preservative.

Serious Adverse Reactions:

• Hypersensitivity/anaphylactic reaction (rare)
• Hypernatremia or fluid overload from excessive administration (seen only in improper use)
• Neonatal gasping syndrome: NEVER use in infants; benzyl alcohol may be fatal.

Warnings:

• Not for use in infants <1 month or pregnant women unless specifically indicated/approved.
• Use in accordance with sterile procedure protocol; discard vial 28 days after first entry.
• If solution is cloudy or contains particulates, discard immediately.
• Overuse or inappropriate administration may result in electrolyte imbalance.

• Product: Bacteriostatic Sodium Chloride 0.9% Injection, USP — 30 mL multiple-dose vials, 25 vials per pack
• Manufacturer: Pfizer (Hospira) | NDC: 0409-1966-07 | UPC: 304091966024
• Preservative: Benzyl alcohol 0.9% (9 mg/mL) — inhibits bacterial growth between vial uses
• Primary use: Diluent and reconstitution medium for injectable medications (IV, IM, SC routes)
• Key clinical applications: Reconstituting lyophilised medications, diluting concentrated injectables, peptide reconstitution (including GLP-1 compounds), and botulinum toxin preparation in aesthetic practice
• Regulatory status: USP-grade, nonpyrogenic, Rx only — requires valid medical license to purchase
• Purchasing advantage: Bulk 25-vial pack format; free US shipping on orders over $100; 5% off first order

• Reconstitution of lyophilised injectables: Dissolves powdered medications (antibiotics, hormones, peptides) into solution for parenteral administration via IV, IM, or SC routes
• Dilution of concentrated injectables: Reduces concentrated drug solutions to the required administration strength prior to injection
• Peptide reconstitution: Widely used by licensed practitioners to reconstitute peptide-based compounds including GLP-1 receptor agonists (e.g. tirzepatide), growth hormone-related peptides (e.g. tesamorelin, retatrutide), and other research-designated injectable peptides
• Aesthetic and MedSpa applications: Used as a reconstitution medium for botulinum toxin products; the isotonic sodium chloride formulation is preferred by some injectors over hypotonic diluents for injection-site comfort considerations
• Multi-dose clinical workflow: The bacteriostatic preservative allows repeated vial entry under aseptic conditions — suitable for high-volume reconstitution settings including outpatient clinics, EMS formularies, and aesthetic practices
• Professional use only: Intended for use by licensed physicians, nurses, pharmacists, EMS professionals, dentists, veterinarians, and other qualified healthcare providers

• Neonatal contraindication — absolute: Benzyl alcohol 0.9% is contraindicated in neonates and premature infants. Benzyl alcohol toxicity in this population is documented and potentially fatal (gasping syndrome). Do not use this product in any formulation intended for neonatal administration.
• Not for large-volume parenteral infusion: This product is a reconstitution and dilution diluent only. It is not indicated as a hydration fluid or large-volume IV infusion solution.
• Aseptic technique required on every draw: The bacteriostatic preservative inhibits bacterial growth but does not sterilise organisms introduced through improper technique. Strict aseptic practice is mandatory for every vial entry.
• Beyond-use dating: After first puncture, multi-dose vials should generally be discarded within 28 days when stored at controlled room temperature, per USP <797> guidance. Verify against your facility's SOPs and applicable state board of pharmacy regulations.
• Visual inspection before use: Inspect each vial before drawing. Discard if the solution is not clear and colourless, or if particulate matter is visible.
• Benzyl alcohol hypersensitivity: Use with caution in patients with known or suspected hypersensitivity to benzyl alcohol. Preservative-free alternatives should be used where indicated.
• Rx only: This product requires a valid medical license to purchase. It is not available for consumer purchase without professional licensure verification.

• Rx verification required: This is a prescription-only product. A valid medical license is required to complete purchase. Mountainside Medical verifies licensure as part of the order process for Rx-designated products.
• Bulk/wholesale pack format: Sold as 25 x 30 mL vials per pack — format and pricing suited to clinical facilities, EMS teams, MedSpas, dental and veterinary practices, and institutional buyers
• Free US shipping: Orders over $100 ship free within the United States
• First-order discount: New customers receive 5% off their first purchase
• Order by phone or email: Phone: +1 (888) 687-4334 | Email: sales@mountainside-medical.com — bulk pricing inquiries and volume orders welcome
• Fast US delivery: Mountainside Medical ships from US-based inventory; online ordering is available with fast dispatch for qualified licensed buyers

• What is bacteriostatic saline and how is it different from regular saline?

  Bacteriostatic saline is a 0.9% sodium chloride (normal saline) solution that contains benzyl alcohol 0.9% as a preservative. The sodium chloride concentration is identical to standard preservative-free saline — isotonic, 9 mg NaCl per mL. The difference is the benzyl alcohol, which inhibits bacterial growth between vial uses. This makes the product safe to use as a multi-dose vial, allowing repeated withdrawals without the contamination risk that would apply to a standard saline vial after its first puncture. Preservative-free normal saline does not contain benzyl alcohol and must be discarded after a single use or after the vial is opened.

• Is normal saline the same as bacteriostatic saline?

  Not exactly. Both are 0.9% sodium chloride solutions, and both are isotonic. But standard normal saline (preservative-free) does not contain a bacteriostatic agent. Bacteriostatic saline contains benzyl alcohol 0.9%, which prevents bacterial contamination between uses. Clinically, the two are not interchangeable in all settings — the benzyl alcohol in bacteriostatic saline is a contraindication in neonates, and some clinical protocols specify preservative-free saline for certain applications. For multi-dose reconstitution and dilution workflows in adult patients, bacteriostatic saline is the appropriate choice.

• Can I use bacteriostatic sodium chloride for peptide reconstitution?

  Yes. Bacteriostatic sodium chloride 0.9% is widely used by licensed practitioners for reconstituting peptide-based injectable compounds, including GLP-1 receptor agonists such as tirzepatide, and growth hormone-related peptides such as tesamorelin and retatrutide. The bacteriostatic preservative extends the usable life of the reconstituted solution compared to using preservative-free saline, which is one reason practitioners in compounding-adjacent clinical settings favour this product for peptide reconstitution. Specific reconstitution volumes and concentrations must be determined by the prescribing or administering healthcare professional according to applicable clinical protocols.

• Can bacteriostatic saline be used for Botox reconstitution?

  Bacteriostatic saline is used by some aesthetic practitioners to reconstitute botulinum toxin products. The isotonic sodium chloride formulation is considered by some injectors to be associated with less injection-site discomfort compared to hypotonic diluents. That said, botulinum toxin manufacturer prescribing information specifies recommended diluents, and practitioners should follow those guidelines. Any reconstitution decision should be made by the licensed injector in accordance with their clinical training and the manufacturer's approved prescribing information.

• Why can't bacteriostatic saline be used in neonates?

  The benzyl alcohol preservative (0.9%, 9 mg/mL) in this product is contraindicated in neonates and premature infants. Benzyl alcohol toxicity in neonates was documented in published case series and FDA communications beginning in the early 1980s, describing a syndrome characterised by metabolic acidosis, gasping respirations, CNS depression, and in some cases death — now referred to as 'gasping syndrome.' Neonates lack the hepatic enzyme capacity to metabolise benzyl alcohol effectively, leading to toxic accumulation of benzoic acid. Preservative-free saline must be used in any application involving neonates.

• How long can a multi-dose vial of bacteriostatic saline be used after first puncture?

  USP General Chapter <797> guidance and standard clinical practice generally support a 28-day beyond-use date for multi-dose vials after first puncture when stored at controlled room temperature (20°C–25°C). However, the applicable beyond-use date can vary depending on your facility's standard operating procedures, your state board of pharmacy regulations, and the specific storage conditions in your clinical environment. Always verify the discard policy with your facility pharmacist and applicable regulatory requirements. Do not use the vial beyond 28 days from first puncture unless your facility SOPs specify otherwise based on regulatory guidance.

• Where can I buy bacteriostatic saline — is it available at pharmacies like Walgreens or CVS?

  Retail pharmacies such as Walgreens and CVS typically stock preservative-free saline for outpatient use. Multi-dose bacteriostatic sodium chloride in the 25-vial bulk pack format is a wholesale clinical supply product, and retail availability is inconsistent. Mountainside Medical supplies this product directly to licensed healthcare professionals with fast US shipping and free delivery on orders over $100. First-time buyers receive 5% off. Orders can be placed online or by calling +1 (888) 687-4334.

• Do I need a medical license to purchase bacteriostatic sodium chloride from Mountainside Medical?

  Yes. Bacteriostatic Sodium Chloride 0.9% Injection is an Rx-only product. A valid medical license is required to purchase. Mountainside Medical verifies licensure as part of the order process for prescription-designated products. This applies to physicians, nurses, pharmacists, EMS professionals, dentists, veterinarians, and other licensed healthcare providers. If you have questions about the licensing verification process, contact the team at sales@mountainside-medical.com or call +1 (888) 687-4334.

• What is the difference between bacteriostatic saline and bacteriostatic water for injection?

  These are two distinct products. Bacteriostatic sodium chloride 0.9% (this product) is an isotonic solution — it contains 9 mg/mL sodium chloride in addition to the benzyl alcohol preservative, giving it the same osmolality as blood and body fluids. Bacteriostatic water for injection (BWFI) is a hypotonic solution — it contains only sterile water and benzyl alcohol, with no sodium chloride. BWFI has lower osmolality and is not isotonic. The choice between the two depends on the medication being reconstituted: some drugs specify one diluent over the other in their prescribing information, and the tonicity of the final reconstituted solution matters for the administration route and patient tolerance.