Endoform® Natural Dermal Template is a type of medical device used for the treatment of chronic and difficult-to-heal wounds such as ulcers, burns, and surgical wounds. It is designed to promote wound healing by providing a scaffold for new tissue growth and providing a protective barrier against infection. The device is made from a natural extracellular matrix derived from ovine (sheep) tissue, which contains various growth factors and proteins that help to support the healing process. Endoform® is typically used in conjunction with other wound care products and can be applied topically or used as a dressing.
- Unique extracellular matrix (ECM) products for the management of acute and chronic wounds
- Provide a natural porous ECM bioscaffold for rapid cell infiltration
- Contain more than 150 ECM proteins known to be important in wound healing
- Contain residual vascular channels to support the establishment of new vasculature
- Can indicate the presence or absence of proteases and help restore protease balance and guide re-application
- Can be used by any wound care provider from day one
How It Works
- Endoform™ Antimicrobial and Endoform™ Natural Restorative Bioscaffold products work in all phases of healing to stabilize, correct, build and organize tissue.
- Endoform™ products are made from AROA ECM™ technology and contain more than 150 extracellular matrix (ECM) proteins that enable it to interact with patient’s cells throughout all phases of healing.(1, 2) Endoform™ products are 85% collagen and 15% important secondary molecules, including structural and adhesion proteins, and glycosaminoglycans (GAGs).(1) Endoform™ products only contain components found in tissue extracellular matrix.
- During the inflammatory phase, chronic wounds are characterized by elevated wound proteases that limit healing by digesting important dermal proteins.(3) Endoform™ products can help indicate the presence or absence of proteases and restores protease balance.(4, 5) If Endoform™ products are not visible in the wound bed at the time of reapplication, this can indicate elevated wound protease activity. However, if Endoform™ is visible, this can indicate that protease balance has been restored.
- Endoform™ products also contain residual vascular channels that facilitate the rapid establishment of a dense capillary network by supporting migrating endothelial cells to establish new vasculature and a robust blood supply to help build new tissue.(6) This process is termed angioconduction.
