MI Paste® Plus (Mint Flavor)

MI Paste Plus Mint is an over‐the‐counter topical dental paste by GC America designed to strengthen tooth enamel and help prevent cavities. Its active ingredient is sodium fluoride 0.20% (w/w) – a standard anticavity concentration – combined with glycerin, xylitol, and a Recaldent® complex (CPP-ACP, a milk-derived casein phosphopeptide–amorphous calcium phosphate) to deliver bioavailable calcium and phosphate to the teeth. In practice, MI Paste Plus Mint is used after regular brushing as a “leave-on” remineralizing treatment. The fluoride acts with the CPP-ACP to rebuild weakened enamel (forming fluorapatite) and inhibit decay, while the minerals help fill in early lesions and block dentin tubules.

Uses (Indications)

MI Paste Plus Mint is used in preventive dental care. Although the FDA label simply states it “aids in the prevention of dental cavities”, in practice dental professionals recommend it for:

• Caries prevention: Helping to harden enamel and protect against new cavity formation (thanks to its fluoride content). It is ideal for patients at medium-to-high risk of caries (e.g. after orthodontics, with active decay, or poor oral hygiene).
• Enamel remineralization (“white spots”): Reversing early demineralization. MI Paste Plus supplies calcium and phosphate ions that rebuild enamel in chalky white-spot lesions (common around braces or after acid erosion).
• Sensitivity relief: Fortifying enamel and occluding exposed dentin tubules can reduce sharp pain from cold, heat, sweets, or acid. (Many users report less sensitivity with regular use.)
• Post-whitening or erosive protection: After professional bleaching or with dietary/acid erosion, it helps re-harden enamel and buffer acids. Stability of enamel is improved due to the extra minerals and fluoride.
• Dry mouth support: In patients with low saliva (xerostomia), MI Paste Plus provides some of the minerals missing from saliva, helping protect enamel from plaque acid.

Note: MI Paste Plus is a dental protective paste, not a medication for infections. It will not treat tooth decay once a cavity has formed (that requires a dentist) and does not affect viruses or systemic health.

How to Use (Directions)

Use MI Paste Plus Mint after your regular brushing routine. According to the product label, do the following:

• Brush and floss your teeth as usual with a regular fluoride toothpaste, then rinse your mouth lightly.
• Apply a pea‐sized amount: Dispense about a pea‐sized drop of MI Paste Plus Mint onto a clean finger (some people wet the finger slightly first).
• Spread on teeth: Gently rub the paste onto all tooth surfaces. Cover the upper teeth evenly, then the lower teeth. (You may also apply it with a clean toothbrush or in a custom tray if directed by your dentist.)
• Leave it on: Do not rinse immediately. Allow the paste to stay on your teeth for about 3 minutes. During this time the fluoride and calcium/phosphate are absorbed into enamel.
• Spit out excess: After 3 minutes, simply spit out any remaining paste. (If possible, avoid eating or drinking for 30 minutes afterward to maximize its effect.)
• Frequency: Use MI Paste Plus Mint twice daily (morning and night) or as directed. Replace the cap after use to keep it fresh.

Children (6–12 years) should use only under a dentist’s guidance and with supervision (to minimize swallowing). The product is not for unsupervised use by children under 6.

Side Effects

MI Paste Plus Mint is very well tolerated by most people, as it acts only on the teeth. Possible effects are:

• Allergic reaction: The paste contains milk protein (casein) and paraben preservatives (hydroxybenzoates). If you have a known milk allergy or sensitivity to parabens, do not use this product. Signs of allergy can include rash, itching, hives, facial swelling, or breathing difficulty. If any allergy symptoms occur, stop use immediately, rinse mouth, and seek medical attention.
• Mild oral irritation: A few users may notice slight gum or palate irritation or a pungent taste. MI Paste Plus is SLS-free and designed to be gentle, so these are uncommon. If oral irritation or sores develop, discontinue use and consult a dentist.
• Fluoride ingestion (overdose): Very large ingestion can cause nausea, vomiting or stomach pain (fluoride toxicity). Always use only the recommended pea-sized amount and spit it out. Keep the paste away from small children. If a child swallows a large amount of MI Paste Plus (far more than used for one brushing), contact Poison Control or seek medical care.
• No systemic effects: There are no known serious systemic side effects from normal use. If tooth sensitivity or discomfort worsens despite use of the paste, or if any new symptoms occur, stop use and see your dentist.

Precautions and Warnings

• Allergy: Do not use MI Paste Plus Mint if you have a sensitivity to milk proteins or to parabens (methyl/propyl/ethyl hydroxybenzoate).
• Children: Keep out of reach of children under 6. For ages 6–12, use only under a dentist’s advice. Ensure children spit out the paste and do not swallow it.
• Pregnancy/Breastfeeding: Because MI Paste Plus is used topically and spat out, minimal fluoride is absorbed. It is generally considered safe if needed during pregnancy or nursing. Still, tell your dentist or physician if you are pregnant or nursing before starting any new oral care product.
• Medical conditions: No special adjustments are usually needed for medical conditions, but inform your dentist if you have severe kidney disease or other conditions affecting minerals. MI Paste contains fluoride, so exposure should be accounted for if you use multiple fluoride sources.
• Drug interactions: None known (it is not a systemic drug). However, do not use other fluoride rinses or toothpaste at the same time to avoid excess fluoride.
• General: MI Paste Plus Mint is not a substitute for daily brushing/flossing and routine dental care. Continue regular dental visits.

Composition

• Active ingredient: Sodium fluoride 0.20% (w/w) – provides the anticavity (anticaries) action.
• Other active component: CPP-ACP (Recaldent®) – a milk casein phosphopeptide–amorphous calcium phosphate complex that delivers calcium and phosphate ions to the tooth surface.
• Inactive ingredients: Casein phosphopeptides-calcium phosphate complex, xylitol, glycerin, D-sorbitol, titanium dioxide (whitening agent), flavoring (mint), propylene glycol, phosphoric acid, sodium carboxymethylcellulose, sodium saccharin, and parabens (methyl/ethyl/propyl-butyl hydroxybenzoate) as preservatives. (Notably, it contains no sodium lauryl sulfate and has low abrasiveness.)

Important Advice

• Use as directed: Always follow the product instructions or your dentist’s advice. Apply MI Paste Plus Mint after brushing and allow it to sit for the recommended time. Consistent use is key – even if sensitivity improves, continue using twice daily to maintain enamel protection.
• Oral hygiene: Continue to brush (with regular toothpaste) and floss daily. MI Paste Plus is an adjunct, not a replacement for routine hygiene.
• Storage: Store at room temperature with the cap closed. Do not freeze. Rinse the cap and nozzle if they become clogged.
• Check dental progress: If after a few weeks of use you notice no benefit (e.g. sensitivity persists or new decay appears), consult your dentist. This product helps prevent decay but cannot reverse a deep cavity; you may need professional treatment.
• Note on dosage: MI Paste Plus Mint is not an “antibiotic”; it does not cure infection. It is a preventive remineralizing treatment. Use only the pea-size amount – more is not better.
• Keep it away: As with any dental product with fluoride, keep the tube out of reach of children to prevent accidental swallowing.

Disclaimer: This information is provided for general understanding only and does not replace professional dental advice. Always consult your dentist or dental hygienist for guidance on proper treatment and usage of dental products.

• Product: MI Paste Plus with Recaldent® — Mint Flavor, 40-gram tube
• Manufacturer: GC America
• Active Ingredients: Sodium fluoride 0.20% (w/w) and Recaldent® CPP-ACP (casein phosphopeptide–amorphous calcium phosphate)
• Primary Use: Topical remineralizing treatment paste for enamel strengthening, cavity prevention, and sensitivity relief — applied after brushing as a leave-on treatment
• Key Differentiator vs. MI Paste Original: Contains sodium fluoride (0.20%); the original MI Paste does not — making MI Paste Plus the appropriate choice for caries prevention alongside remineralisation
• SLS-Free and Low Abrasion: Formulated without sodium lauryl sulfate; suitable for patients with oral sensitivity or erosion-compromised enamel
• Availability: Over-the-counter (OTC) — no prescription required; available for direct purchase and bulk ordering through Mountainside Medical

• Caries Prevention (Medium-to-High Risk Patients): Intended to support enamel hardening and reduce the risk of new cavity formation in patients identified as moderate-to-high caries risk — including those with active decay history, poor oral hygiene, or undergoing or post-orthodontic treatment
• White Spot Lesion Management (Post-Orthodontic): Designed to support remineralisation of early enamel demineralisation presenting as chalky white-spot lesions — a common presentation following fixed orthodontic appliance therapy
• Dentinal Hypersensitivity: Intended to support occlusion of exposed dentin tubules through mineral deposition, reducing sharp thermal and chemical sensitivity in patients with exposed dentin
• Post-Whitening Enamel Protection: Designed for use following professional bleaching procedures to support enamel re-hardening and buffer against post-whitening acid sensitivity
• Xerostomia (Dry Mouth) Support: In patients with reduced salivary flow, MI Paste Plus is intended to supplement the calcium and phosphate ions that saliva normally contributes — supporting enamel protection in the absence of adequate natural mineralisation
• Tray Delivery for Clinical Application: Can be dispensed into custom-fitted dental trays for extended or targeted contact in clinical or at-home professional use — particularly in patients with significant enamel erosion or widespread white spot lesions

• Milk Protein Allergy — Absolute Contraindication: MI Paste Plus contains Recaldent® CPP-ACP derived from bovine casein. Do not use in any patient with a known or suspected milk protein allergy. Signs of allergic reaction include rash, hives, itching, facial swelling, or difficulty breathing — discontinue immediately and seek medical attention if any allergic symptoms occur
• Paraben Sensitivity: The preservative system contains methyl, ethyl, propyl, and butyl hydroxybenzoate (parabens). Patients with documented paraben sensitivity should not use this product
• Children Under 6 — Not for Use: Keep out of reach of children under 6 years of age. Not appropriate for use in this age group
• Children Ages 6–12 — Supervised Use Only: Use in this age group only under the advice and guidance of a dental professional, with adult supervision to prevent swallowing
• Fluoride Ingestion: Use only the recommended pea-sized amount. Ingestion of large quantities of fluoride can cause nausea, vomiting, or gastric discomfort. If accidental ingestion of a large amount occurs, contact Poison Control (1-800-222-1222)
• Concurrent Fluoride Products: Do not use simultaneously with other fluoride rinses or high-concentration fluoride toothpastes to avoid excess cumulative fluoride exposure
• Active Cavities: MI Paste Plus is not a treatment for established dental caries. It cannot reverse decay that has progressed beyond early enamel demineralisation — patients with active cavities require professional dental intervention

• Prescription Not Required: MI Paste Plus with Recaldent® is an OTC product — no prescription or medical license is required to purchase. Available for direct purchase by consumers, patients, and healthcare professionals
• Bulk and Wholesale Ordering: Dental practices, clinics, and institutional buyers ordering in volume are encouraged to contact Mountainside Medical's sales team directly for wholesale pricing: sales@mountainside-medical.com or +1 (888) 687-4334
• First-Order Discount: New customers receive 5% off their first purchase at Mountainside Medical
• Free Shipping Threshold: Free US shipping on orders over $100
• Shipping Region: United States; Mountainside Medical infrastructure supports US-wide delivery
• Contact for Orders: Phone: +1 (888) 687-4334 | Email: sales@mountainside-medical.com

• What is MI Paste Plus used for?

  MI Paste Plus is a topical remineralizing paste used after brushing to help prevent cavities and strengthen tooth enamel. Its FDA-cleared indication is anticavity protection via sodium fluoride 0.20% (w/w). In dental practice, it is also recommended to support remineralisation of early enamel demineralisation (white spot lesions), reduce dentinal sensitivity, protect enamel after professional whitening, and support patients with dry mouth who lack adequate mineral flow from saliva. It does not treat active cavities — those require professional dental intervention.

• What is the difference between MI Paste and MI Paste Plus?

  The critical difference is fluoride. MI Paste Plus contains sodium fluoride 0.20% (w/w) in addition to Recaldent® CPP-ACP. The original MI Paste contains CPP-ACP only — no fluoride. For most adult patients at medium-to-high caries risk, MI Paste Plus is the clinically appropriate choice because it combines enamel remineralisation with FDA-cleared cavity prevention. MI Paste without fluoride is typically used in specific cases where fluoride exposure must be controlled, such as very young children or patients already on high-dose prescription fluoride. If your dentist recommended MI Paste Plus, do not substitute the original formulation.

• How do I use MI Paste Plus correctly?

  Brush and floss with your regular fluoride toothpaste first, then rinse lightly. Apply a pea-sized amount of MI Paste Plus Mint to a clean finger or toothbrush and rub it evenly across all tooth surfaces. Leave it on for three minutes — do not rinse. Spit out any remaining paste after three minutes. Avoid eating or drinking for 30 minutes after application to allow the fluoride and CPP-ACP adequate contact time with the enamel. Use twice daily (morning and night) or as directed by your dentist. It can also be applied using a custom dental tray for more targeted use.

• Does MI Paste Plus require a prescription?

  No. MI Paste Plus is an over-the-counter (OTC) product in the United States. It does not require a prescription. The sodium fluoride concentration of 0.20% (w/w) falls within FDA OTC monograph limits. It is heavily associated with dental professionals because it is recommended in clinical settings, which leads many patients to assume a prescription is required — it is not. You can purchase it directly from Mountainside Medical without a prescription.

• What are the ingredients in MI Paste Plus?

  Active ingredient: sodium fluoride 0.20% (w/w). The Recaldent® CPP-ACP (casein phosphopeptide–amorphous calcium phosphate) complex delivers bioavailable calcium and phosphate to the tooth surface. Key inactive ingredients include glycerin, D-sorbitol, xylitol, sodium carboxymethylcellulose, titanium dioxide, mint flavouring, propylene glycol, phosphoric acid, sodium saccharin, and parabens (methyl, ethyl, propyl, and butyl hydroxybenzoate) as preservatives. The product is formulated without sodium lauryl sulfate (SLS) and has low abrasiveness.

• What are the side effects of MI Paste Plus?

  For most users, MI Paste Plus produces no side effects when used as directed. The most significant risk is allergic reaction in patients with a milk protein (casein) allergy — the Recaldent® CPP-ACP complex is derived from bovine casein. Symptoms of allergic reaction can include rash, hives, facial swelling, or difficulty breathing; discontinue immediately and seek medical attention. Patients with paraben sensitivity should also review the ingredient list. Mild oral irritation is uncommon but possible. Large accidental ingestion of fluoride (far beyond normal use amounts) can cause nausea or gastric discomfort — contact Poison Control if this occurs.

• Is MI Paste Plus safe for children?

  MI Paste Plus is not appropriate for children under 6 years of age. For children aged 6–12, use is appropriate only under the guidance of a dental professional and with adult supervision to prevent swallowing. Children in this age group should use only a pea-sized amount and be supervised to ensure they spit it out. Keep the tube out of reach of young children. If a dentist has specifically recommended MI Paste Plus for a child in this age range, follow their dosage and frequency guidance.

• Where can I buy MI Paste Plus?

  MI Paste Plus is available for direct purchase at Mountainside Medical without a prescription. It is not commonly stocked in standard pharmacies or retail stores despite being an OTC product, because it is primarily distributed through dental professional channels. Dental practices also dispense it in-office, often at higher prices than direct-purchase platforms. Mountainside Medical offers competitive wholesale pricing, free US shipping on orders over $100, and 5% off for new customers. Dental practices and clinics purchasing in bulk should contact the sales team at sales@mountainside-medical.com or +1 (888) 687-4334 for wholesale pricing.

• Can MI Paste Plus fix cavities or reverse tooth decay?

  No. MI Paste Plus is a preventive treatment, not a restorative one. It can support remineralisation of very early enamel demineralisation — the pre-cavity stage where enamel has lost minerals but structural integrity remains. Once decay has progressed through the enamel surface into dentin, MI Paste Plus cannot reverse it. Active cavities require professional dental treatment (drilling and filling, or other restorative intervention). MI Paste Plus is designed to prevent that progression from happening, not to treat decay once it has formed.