Sulfamethoxazole and Trimethoprim 800mg/160mg tablets are an antibiotic combination used to treat a variety of bacterial infections. Commonly prescribed for urinary tract infections (UTIs), respiratory infections, and gastrointestinal infections, this medication works by inhibiting bacterial growth. It is also effective against certain types of pneumonia and other infections caused by susceptible bacteria. Consistent use as directed by a healthcare provider is crucial for effective treatment and preventing antibiotic resistance.
Sulfamethoxazole and Trimethoprim DS Tablets combine two potent antibacterial agents in double-strength formulation, meticulously produced by Aurobindo Pharma USA. This synergistic antibiotic blend is formulated for the effective treatment of a variety of bacterial infections, delivering enhanced efficacy in a convenient, dual-action dosage. Each bottle contains 100 double-strength tablets, ensuring an optimal supply for prescribed regimens. Designed to tackle infections with precision, these tablets represent Aurobindo Pharma's commitment to quality and patient care.
Product Details and Features:
Active Ingredients: Sulfamethoxazole 800 mg, Trimethoprim 160 mg per tablet
Form: Double-strength oral tablets
Quantity: 100 tablets per bottle, ideal for therapeutic consistency and adherence
Indications: Effective against urinary tract infections, respiratory infections, gastrointestinal infections, and various other bacterial infections where the use of a broad-spectrum antibiotic is required
Packaging: Securely sealed to ensure product integrity and stability to the end user
Therapeutic Class: Antibiotic combination providing broad bacterial spectrum coverage
Directions for Use:
1. Dosage: Follow the dosing instructions prescribed by your healthcare provider, typically one tablet every 12 hours. The duration can vary based on the infection and clinical response.
2. Administration: Tablets should be taken orally with a full glass of water. Ensure adequate hydration during the course of treatment to prevent crystalluria.
3. Meal Consideration: This medication can be taken with or without food. However, taking it with meals may reduce the risk of stomach upset.
Mechanism of Action:
Sulfamethoxazole and trimethoprim work synergistically by blocking sequential steps in bacterial folic acid synthesis:
-
Sulfamethoxazole: Inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA).
-
Trimethoprim: Inhibits dihydrofolate reductase, preventing conversion of dihydrofolic acid to tetrahydrofolic acid.
This dual inhibition effectively halts bacterial growth, providing a potent bacteriostatic effect.
Side Effects:
While generally well-tolerated, some patients may experience side effects including:
- Nausea or vomiting
- Rash or skin reactions
- Loss of appetite or stomach pain
- Fatigue or headaches
Severe side effects may include allergic reactions, unanticipated bruising/bleeding, persistent sore throat, or signs of a severe skin reaction. Seek medical advice if these occur.
Warnings:
-
Hypersensitivity: Contraindicated in individuals with a history of allergy to sulfonamides or trimethoprim.
-
Pregnancy and Lactation: Use only if clearly needed during pregnancy and after assessing the benefit-risk ratio during breastfeeding.
-
Blood Disorders: Exercise caution in patients with pre-existing blood dyscrasias or G6PD deficiency.
-
Renal/Hepatic Impairment: Monitor kidney and liver function regularly during therapy in vulnerable patients.
-
Drug Interactions: Can interact with warfarin and certain antihyperglycemics, adjusting therapy as necessary.
For comprehensive bacterial infection management, trust Sulfamethoxazole and Trimethoprim DS by Aurobindo Pharma USA, exemplifying reliability in pharmaceutical excellence.
Skip to content
