Sulfamethoxazole and Trimethoprim 800mg/160mg Double Strength 100 Tablets (RX)

Prescription Strength Antibiotic – Trusted Solution for Bacterial Infections!

Sulfamethoxazole and Trimethoprim 800mg/160mg Double Strength Tablets USP, 100 Count by Rising Pharmaceuticals is a top-rated, FDA-approved, broad-spectrum prescription antibiotic combination designed to treat a wide range of bacterial infections. Known also as SMX-TMP DS or Bactrim DS (generic), this medication is clinically trusted for its dual-action effectiveness and rapid symptom relief. Perfect for both outpatient and hospital settings, this double-strength tablet pack offers physician-recommended, high quality infection care.

What Are Sulfamethoxazole and Trimethoprim 800mg/160mg Tablets?

Sulfamethoxazole and Trimethoprim, also known as co-trimoxazole, is a combination antibiotic medication. The “double strength” (DS) tablet contains 800mg of sulfamethoxazole and 160mg of trimethoprim. Typically, these tablets are supplied in bottles or packs of 100 for prescription use.

Uses

Sulfamethoxazole and trimethoprim tablets are used to treat a variety of bacterial infections, such as:

• Urinary tract infections (UTIs)
• Respiratory infections: e.g. acute exacerbations of chronic bronchitis, pneumonia (including Pneumocystis jirovecii pneumonia in people with HIV/AIDS)
• Gastrointestinal infections: e.g. traveler’s diarrhea, shigellosis
• Skin and soft tissue infections (such as some forms of MRSA)
• Ear infections (acute otitis media)
• Certain types of prostatitis
• Prevention and treatment of Pneumocystis pneumonia (PCP) in immunocompromised patients

NOTE: This combination is not effective against viral or fungal infections.

Order Sulfamethoxazole and Trimethoprim 800mg/160mg DS Tablets, 100 Count

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Uses and Applications

Sulfamethoxazole and Trimethoprim (SMX-TMP) 800mg/160mg Double Strength is indicated for the treatment and management of multiple bacterial infections caused by susceptible microorganisms, including:

• Urinary Tract Infections (UTI)
• Acute Exacerbations of Chronic Bronchitis
• Traveler’s Diarrhea
• Shigellosis
• Otitis Media (ear infections)
• Pneumocystis Jirovecii Pneumonia (PCP)
• Skin and Soft Tissue Infections (including MRSA)
• Prostatitis
• Respiratory Tract Infections
• Certain Gastrointestinal infections
• Prevention of infection in immunocompromised patients

Specifications

• Active Ingredients: Sulfamethoxazole 800 mg / Trimethoprim 160 mg per tablet (Double Strength formula)
• Manufacturer: Rising Pharmaceuticals
• NDC: 5723-70233-01
• UPC: 357237233016
• Dosage Form: Oral Tablet
• Count: 100 Tablets per bottle
• Prescription Required: Yes
• FDA Approved: Yes
• Brand Equivalent: Bactrim DS, Septra DS

How to Use

• Take exactly as prescribed by your healthcare provider.
• Route: Oral, swallow whole with a full glass of water.
• With or Without Food: Can be taken with or without food. If stomach upset occurs, take with food or milk.
• Stay hydrated: Drink ample fluids to prevent kidney stones and increase urinary flow.

Dosage and Administration

• Standard Adult Dosage (for most indications): 1 double strength tablet (800mg/160mg) every 12 hours for 10–14 days (dose, duration, and frequency may vary by infection type and patient condition).
• For Pneumocystis Jirovecii Pneumonia: Higher or weight-based doses may be prescribed.
• Pediatric dosing is weight-based; consult your pediatrician.
• Complete the entire prescribed course, even if symptoms improve early, to prevent relapse and antibiotic resistance.
• Do not skip doses. If a dose is missed, take as soon as possible unless it’s almost time for the next dose.

Drug Interactions

Sulfamethoxazole and Trimethoprim can interact with several medications. Inform your healthcare provider of all medications or supplements you are taking, especially:

• Blood thinners (warfarin)
• ACE inhibitors, ARBs (for hypertension)
• Diuretics (water pills)
• Anti-seizure medications (phenytoin)
• Antidiabetic drugs (sulfonylureas)
• Methotrexate
• Cyclosporine
• Digoxin
• Antidepressants (tricyclics)
• Lithium

Keywords: Bactrim warfarin interaction, SMX TMP ACE inhibitors, Bactrim and digoxin, Bactrim drug interactions, sulfa drug contraindications

Side Effects

Common Side Effects:

• Nausea, vomiting
• Diarrhea, loss of appetite
• Mild headache
• Mild rash

Serious Side Effects (seek immediate medical attention):

• Severe skin reactions: Stevens-Johnson syndrome, toxic epidermal necrolysis (blistering, peeling, rash, burning in eyes)
• Signs of blood disorders: Unusual bruising/bleeding, persistent sore throat, fever
• Signs of liver problems: Yellowing of skin or eyes, dark urine, severe stomach pains
• Signs of kidney problems: Changes in urine output, severe lower back pain
• Allergic reaction: Swelling of face/lips/tongue/throat, difficulty breathing

Warnings & Precautions

• Allergic to sulfa drugs: Do not use if you have a known sulfa allergy.
• Pregnancy & Breastfeeding: Not recommended, especially in late pregnancy or for infants under 2 months.
• Blood Disorders: Increased risk for individuals with folate deficiency, G6PD deficiency, or advanced age.
• Kidney and Liver Disease: Use with caution; adjust dosage as directed by your physician.
• Photosensitivity: May cause sun sensitivity—use sunscreen and protective clothing.
• Superinfection Risk: Prolonged use may result in overgrowth of non-susceptible organisms.