Tobramycin Sulfate Injection 40 mg/mL, 2 mL Vials (Multi-Dose, Tray of 25) – Fresenius Kabi

Tobramycin Sulfate Injection 40 mg/mL is a high-potency antibiotic for serious bacterial infections. This sterile injectable solution (80 mg per 2 mL vial) contains tobramycin sulfate – an aminoglycoside broad-spectrum antibiotic – in a convenient 2 mL multi-dose vial. Each tray includes 25 vials, ensuring a reliable supply for hospital pharmacies and clinical settings. Fresenius Kabi’s pharmaceutical-grade manufacturing guarantees consistent, highly purified medication that meets strict quality standards. Tobramycin Injection comes ready-to-use for intravenous infusion (after appropriate dilution) and is intended for use under doctor supervision in acute care.

As a powerful antibacterial and aminoglycoside medication, Tobramycin Injection targets a wide range of gram-negative organisms (e.g. Pseudomonas aeruginosa, Escherichia coli, Klebsiella spp.) and some gram-positive bacteria when used in combination therapy. It works by inhibiting bacterial protein synthesis, providing rapid, bactericidal action against entrenched infections. Healthcare providers rely on Tobramycin for hospital antibiotic therapy in complex cases: ventilator-associated pneumonia, cystic fibrosis lung infections, bloodstream sepsis, complicated urinary tract infections, skin and bone infections (osteomyelitis), and other serious infectious diseases. Its high 40 mg/mL concentration delivers potent dosing in a small volume, which is critical for critical-care patients.

Key Features & Benefits:

• Broad-Spectrum Antibiotic Injection: Delivers Tobramycin (40 mg per mL) in each 2 mL vial to fight a wide range of bacteria, especially Gram-negative pathogens. Ideal for treating severe hospital-acquired infections like pneumonia, sepsis, and urinary tract infections.
• Multiple-Dose Convenience: Each vial contains 80 mg Tobramycin with a built-in preservative system, allowing multiple withdrawals from the same vial. This cost-effective multi-dose design (2 mL vial with 13 mm seal) reduces waste and streamlines pharmacy workflow.
• Sterile Injectable Solution: Ready-to-use, clear and colorless solution meeting USP standards. Formulated with stabilizers (sodium metabisulfite and EDTA) for extended shelf-life and potency. Requires dilution for IV infusion using compatible fluids (such as normal saline or D5W) before administration.
• Pack of 25 Vials: Supplied in a convenient tray (25 vials per pack) to keep hospital stock well-supplied. Compact and bar-coded packaging facilitates inventory management. The tray format ensures quick access during emergencies or routine therapy.
• Trusted Fresenius Kabi Quality: Produced by Fresenius Kabi, a leader in sterile IV therapies. This prescription antibiotic undergoes rigorous quality control and is USP-compliant. (NDC/GTIN references: #63323-306-02, product code C300602.)

Indications & Usage:

Tobramycin Injection is indicated for use by healthcare professionals to treat proven or strongly suspected severe infections caused by susceptible bacteria. Typical uses include: respiratory tract infections (e.g. pneumonia, bronchitis, cystic fibrosis pulmonary infections), septicemia and bloodstream infections, complicated skin and soft tissue infections, bone/joint infections (osteomyelitis), and urinary tract infections (including pyelonephritis). It is often used in combination with other antibiotics (such as beta-lactams or vancomycin) to broaden coverage, especially in Gram-positive or mixed infections. This antibiotic should be used according to institutional protocols and drug-resistance data.

Administration & Dosage:

Tobramycin Injection is administered by intravenous infusion (IV) after diluting the required dose in a suitable IV fluid. Each milliliter contains 40 mg of Tobramycin (as Tobramycin Sulfate) in a buffered aqueous solution. Dosage is individualized by patient weight, renal function, and severity of infection; follow the prescribing information and hospital guidelines. The multi-dose vials contain a mild preservative, but aseptic technique is required: once opened, use each vial promptly and discard any unused portion according to protocol.

Storage & Handling:

Store at controlled room temperature (typically 20–25 °C / 68–77 °F) away from light and excessive heat. Do not freeze. The preservative in this formulation allows multiple withdrawals, but each vial is single-patient use and should be discarded 28 days after first entry, per hospital policy. The 2 mL vial’s 13 mm rubber stopper is latex-free, and the solution remains clear and colorless when properly preserved.

Why Choose Fresenius Kabi Tobramycin Injection?

Fresenius Kabi’s Tobramycin Injection combines potent, targeted antibiotic therapy with multi-dose convenience for hospitals and clinics. The high concentration delivers effective doses in a small volume, reducing infusion times while maximizing bacterial kill. The multi-dose vial saves pharmacy time and cost without sacrificing sterility, as long as proper technique is followed. Healthcare professionals trust this injectable Tobramycin product for its consistent performance in fighting drug-resistant Gram-negative infections. Backed by Fresenius Kabi’s commitment to pharmaceutical excellence, this injection is a top choice for enhancing patient care in ICUs and specialty hospitals.

Tobramycin Sulfate Injection 40 mg/mL (2 mL multi-dose vial, 25/Tray) is a prescription antibiotic injection designed to treat life-threatening bacterial infections. It offers hospital-grade, broad-spectrum coverage against tough Gram-negative pathogens and is a critical component in antibiotic therapy regimens. For medical centers seeking a reliable, high-strength aminoglycoside antibiotic solution, Fresenius Kabi’s Tobramycin injection ensures sterile quality, multi-dose efficiency, and the powerful anti-infective performance that emergency and critical-care teams demand.