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Promethazine HCl for Injection 50 mg / mL Ampules 1 mL x 25/Tray

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Original price $ 185.50
Current price $ 155.00
SKU 39822-5550-06
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Promethazine HCl for Injection 50 mg / mL Ampules 1 mL x 25/Tray. Promethazine hydrochloride is a phenothiazine derivative which possesses antihistaminic, sedative, antimotion-sickness, antiemetic, and anticholinergic effects. Promethazine is a competitive H1 receptor antagonist, but does not block the release of histamine. Structural differences from the neuroleptic phenothiazines result in its relative lack (1/10 that of chlorpromazine) of dopamine antagonist properties. Clinical effects are generally apparent within 5 minutes of an intravenous injection and within 20 minutes of an intramuscular injection. Duration of action is four to six hours, although effects may persist up to 12 hours. Promethazine hydrochloride is metabolized in the liver, with the sulfoxides of promethazine and N-desmethylpromethazine being the predominant metabolites appearing in the urine. Following intravenous administration in healthy volunteers, the plasma half-life for promethazine has been reported to range from 9 to 16 hours. The mean plasma half-life for promethazine after intramuscular a nistration in healthy volunteers has been reported to be 9.8 ± 3.4 hours.

  •  Store at 20 to 25°C (68 to 77°F) [See USP Controlled Room Temperature].
  • Protect from light. Keep covered in carton until time of use.
  • Do not use if solution has developed color or contains a precipitate.
  • Brand: X-Gen Pharmaceuticals
  • Size: 50 mg / mL Ampules 1 mL x 25 per tray

 NDC: 39822-5550-06

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