Hospira Sterile Water for Injection is a pharmaceutical-grade, non-pyrogenic sterile water intended for use as a solvent or diluent for the preparation and reconstitution of parenteral (injectable) medications. Manufactured by Pfizer Injectables, this product comes conveniently packaged in 10 mL single-dose vials, with 25 vials per tray, ensuring sterility and quality for every administration.
What It Is Used For
Hospira Sterile Water for Injection is primarily used as a sterile diluent to:
- Reconstitute or dissolve drugs for intravenous (IV), intramuscular (IM), or subcutaneous (SC) injection
- Prepare medications that require mixing with sterile water prior to administration
- Flush IV lines when sterile conditions are required
Important: Sterile Water for Injection can never be administered alone by IV due to risk of hemolysis. Always use as directed with appropriate medication or as part of a compound preparation.
Product Details & Features
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NDC: 0409-4887-10
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Manufacturer: Pfizer Injectables (Hospira)
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Pack Size: 25 Single-Dose Vials (10 mL each)
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Sterile & Non-Pyrogenic: Provides maximum safety in clinical settings
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Latex-Free: Packaged in latex-free materials to minimize allergy risks
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Ready-to-Use: Vials are individually sealed for single-use to maintain sterility and minimize waste
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Universal Compatibility: Suitable for use with a wide range of medications requiring sterile dilution
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Clear, Colorless Solution: Easy visual inspection for safety
Directions for Use
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Inspect Vial: Ensure the solution is clear and vial is intact—do not use if particulate matter or discoloration is seen.
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Aseptic Technique: Use sterile procedures during preparation to avoid contamination.
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Withdraw Solution: Draw required volume into a sterile syringe.
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Mix with Medication: Inject sterile water into the vial or ampule containing the medication to be reconstituted or diluted, following specific medication instructions.
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Administer as Directed: Only inject or infuse the resultant solution per your provider’s or medication’s guidelines.
Dosage
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Dosage & Volume: Determined by the medication being reconstituted or diluted. ALWAYS follow the specific guidelines provided with the medication and by a licensed healthcare professional.
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Single-Use Only: Discard any unused portion; do not save for later use to maintain sterility and avoid contamination.
Allergies
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Formulation: Free of preservatives, bacteriostatic agents, and latex.
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Allergic Reactions: Rare, but consult your provider if you have specific allergies to injection components or materials.
Drug Interactions
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With Other Drugs: Hospira Sterile Water for Injection is only a diluent and does not interact chemically with other medications.
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Preparation: If mixed with drugs, always verify compatibility and stability per medication guidelines.
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Never Use Alone Intravenously: Administration of only sterile water can lead to significant adverse effects including hemolysis.
Side Effects & Warnings
Possible Side Effects
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Hemolysis: If large volumes are administered intravenously without solutes
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Injection Site Reactions: Mild irritation or redness at injection site (rare)
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Water Intoxication or Electrolyte Disturbances: Possible if used inappropriately
Warnings & Precautions
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For Single Use Only: Discard unused portions to avoid contamination and infection risk.
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Not for Direct Infusion: Do not use as a direct intravenous infusion; must be combined with other medication or agents as directed.
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Pediatric & Geriatric Use: Exercise caution and always consult a healthcare provider.
- Do Not Use If Solution is Not Clear or Container is Damaged
Consult your physician or pharmacist for correct usage, compatibility, and safety precautions specific to the drug being prepared.
Hospira Sterile Water for Injection 10 mL Single-Dose Vials by Pfizer Injectables are the trusted choice in hospitals, clinics, and pharmacies for safe, effective reconstitution of injectable medications. Ensure optimal results and patient safety—choose Pfizer’s high-quality sterile water for all your medical compounding needs.
- Drug reconstitution: Intended as a sterile diluent to reconstitute lyophilised or powdered medications (e.g., antibiotics, biologics) before parenteral administration, follow the specific reconstitution instructions for the medication being prepared
- IV, IM, and subcutaneous preparation: Suitable for use in preparing medications intended for intravenous (IV), intramuscular (IM), or subcutaneous (SC) injection, in accordance with medication-specific guidelines
- Single-preparation workflows: Best suited to single-dose drug preparation, where only one draw from the diluent vial is required for repeated dilution from a single vial, bacteriostatic water for injection is the clinically appropriate alternative
- Preservative-sensitive applications: Preferred diluent when the medication, patient population, or clinical protocol requires a preservative-free diluent, including neonatal applications where benzyl alcohol is contraindicated
- Clinical settings: Used across hospital pharmacies, ambulatory infusion centres, urgent care and emergency medicine settings, aesthetic and medspa practices, and compounding workflows requiring sterile, additive-free diluent
This product is intended for use by qualified healthcare professionals or under the guidance of a licensed medical provider. It is not a substitute for professional medical advice, diagnosis, or treatment.
- Never administer alone by IV infusion: Sterile Water for Injection must never be administered as a standalone intravenous infusion. The near-zero osmolality of sterile water causes osmotic lysis of red blood cells (hemolysis) when infused directly into the bloodstream. This is an FDA-labelled contraindication and a documented patient safety risk
- Single-use only: Each vial is intended for single use. Discard any unused portion immediately after preparation. Do not re-seal, store, or draw from a previously opened vial; doing so compromises sterility and creates contamination risk
- Inspect before use: Do not use if the solution is not clear and colourless, if particulate matter is visible, or if the vial seal or container is damaged in any way
- Aseptic technique required: Use strict aseptic technique throughout preparation. This product does not contain antimicrobial preservatives. Contamination introduced during preparation is not neutralised
- Not interchangeable with bacteriostatic water: Sterile Water for Injection and Bacteriostatic Water for Injection are distinct USP products with different preservative profiles, vial formats, and clinical indications. Verify the correct diluent specification for each medication being prepared
- Paediatric and neonatal use: Exercise caution. Consult a licensed healthcare provider for all paediatric dosing and diluent selection. Sterile Water for Injection is preservative-free and does not carry benzyl alcohol contraindication risk; however, volume and preparation guidelines must be followed precisely
- Drug compatibility: As a diluent vehicle, Hospira Sterile Water for Injection does not interact chemically with other medications. However, always verify the compatibility and stability of the specific drug being reconstituted per the medication's prescribing information before administration
This product is intended for use by qualified healthcare professionals or under the guidance of a licensed medical provider. It is not a substitute for professional medical advice, diagnosis, or treatment.
Rx Only. Hospira Sterile Water for Injection is a prescription product. It may only be purchased by or for use under the supervision of a licensed healthcare professional. It is not intended for use by unlicensed individuals or for non-clinical consumer use.
The product information presented on this page is intended to support licensed healthcare professionals in making informed procurement decisions. It is not intended to replace the full prescribing information, FDA-approved labelling, or clinical judgement of a qualified provider. Always refer to the current FDA-approved package insert for complete prescribing, preparation, compatibility, and safety information prior to use.
Sterile Water for Injection, USP, must never be administered alone by intravenous infusion. Intravenous administration of hypotonic solutions lacking solute can cause hemolysis and other serious adverse effects. Use only as a diluent or solvent for medications as directed by a licensed healthcare provider and in accordance with the specific medication's prescribing information.
Mountainside Medical Equipment is a licensed wholesale distributor of medical supplies and pharmaceutical products in the United States. Product availability, pricing, and shipping terms are subject to change. For regulatory, clinical, or formulary inquiries, contact sales@mountainside-medical.com or +1 (888) 687-4334.
This page does not constitute medical advice. The clinical information provided reflects current FDA labelling and USP standards at the time of publication and is subject to revision. Mountainside Medical does not assume liability for clinical decisions made on the basis of information on this page without independent verification against current prescribing information and applicable clinical guidelines.