Skip to content

Added to your cart:

Cart subtotal

View cart (2) Checkout
Best Selling Products Mi Paste MI Paste Mint Flavor Mouth Oral Care Products Sjogren's Syndrome Dry Mouth Products Toothpastes Enamel Repair Toothpastes Featured Medical Products MI Paste Strawberry Dental Supplies Mi Paste for Kids Sodium Fluoride 1.1% MI Paste Melon Flavor MI Paste Vanilla Flavor Dry Mouth Treatments Personal Care and Hygiene Products MI Paste Tutti Frutti MI Paste 10-Pack Wholesale Boxes Colgate Prevident Medical Supplies

Filters

Availability
Price
$
-
$
$0 $209
Vendor
Collection
Tags

Mi Paste and MI Paste Plus

MI Paste and MI Paste Plus

MI Paste® is a topical dental cream (by GC America) formulated to strengthen tooth enamel. Mi paste contains a milk-derived protein complex called CPP-ACP (marketed as “Recaldent”) which slowly releases bioavailable calcium and phosphate onto tooth surfaces. In other words, MI Paste provides the same mineral building blocks (calcium, phosphate, and optionally fluoride in the “Plus” version) that healthy saliva supplies. By delivering these minerals directly, MI Paste helps rebuild (remineralize) early tooth decay (such as white spot lesions) and harden enamel. This remineralization effect can also make teeth less sensitive, since it helps “fill in” microscopic defects in the enamel. (The manufacturer advertises it as the first topical crème that releases Ca/P for treating non-cavitated demineralization.

Composition & Mechanism

  • MI Paste® (original): Contains Recaldent (CPP-ACP) derived from milk. The CPP (casein phosphopeptides) molecules stabilize amorphous calcium phosphate (ACP) and adhere to tooth surfaces and plaque, delivering calcium and phosphate ions where saliva flow is low or teeth are demineralized. This remineralizes early “white-spot” lesions and can help soothe dentin hypersensitivity. Importantly, it does not contain fluoride, making it safe for young children (even under 6) and pregnant women when fluoride use may be a concern.

  • MI Paste Plus®: Everything in MI Paste plus 0.2% sodium fluoride (anti-cavity agent). The fluoride works with the delivered calcium and phosphate to form fluorapatite, which is more resistant to acid. Thus MI Paste Plus not only rebuilds enamel but also provides an anticavity (anticaries) effect. The inclusion of fluoride means it is recommended for patients at higher risk of cavities, but young children should use it only under supervision (to avoid swallowing excess fluoride).

GC America notes that MI Paste and MI Paste Plus are “the first of their kind” containing milk protein and (for Plus) fluoride. They supply minerals needed when saliva is insufficient, and MI Paste Plus supplies all three ions (calcium, phosphate, fluoride) whereas the original MI Paste supplies just calcium and phosphate. Both formulas are SLS‐free (gentle on soft tissues) and have low abrasiveness.

Uses (Indications)

Both products are used as preventive care aids in situations requiring enamel strengthening and sensitivity relief:

  • Demineralization and White spots: Ideal for early (non-cavitated) caries lesions. MI Paste products deliver minerals to “treat white spot lesions and non-cavitated tooth demineralization”. Dentists often recommend them after orthodontic treatment or heavy fluoride bleaching, when enamel needs rebuilding.
  • Sensitivity relief: By depositing calcium and phosphate, CPP-ACP can occlude exposed dentin tubules. Both MI Paste and MI Paste Plus have a desensitizing effect. GC explicitly recommends MI Paste for dentin hypersensitivity and for sensitivity after cleaning or whitening, and MI Paste Plus for patients who experience tooth sensitivity (before/after whitening or professional cleaning).
  • Cavity prevention: MI Paste Plus (with fluoride) can help prevent new cavities in at-risk patients, thanks to its fluoride content. The original MI Paste (no fluoride) is not a substitute for anticavity treatments, so it’s mainly used when fluoride use must be limited (e.g. very young children) or as an adjunct for remineralization.
  • Dry mouth and erosion: Both products are useful when saliva is low (xerostomia) or diets are acidic. They help neutralize acid pH and supply lacking minerals, protecting against erosion and decay.
  • General oral maintenance: Many users with disc treatments or crowns use MI Paste to keep enamel strong. MI Paste Plus, being anticavity, is recommended as part of preventive regimens (e.g. “ongoing dental health program” for adults, seniors).

Note: MI Paste products do not treat active cavities that already require drilling and filling—they are preventive. They also have no effect on viruses or systemic conditions.

How to Use

MI Paste and MI Paste Plus are used like a toothpaste/crème, usually after regular brushing with a normal fluoride toothpaste (to maximize benefit).

  • Frequency: Apply twice daily (morning and night) or as instructed by your dentist.
  • Application: Squeeze a pea-sized amount onto a clean finger or onto a soft toothbrush. Spread or brush it onto all tooth surfaces. (Some people also use custom trays to hold it on teeth if recommended.)
  • Dwell time: Leave it on for about 3 minutes. Spit out the excess paste. Do not rinse with water immediately—the remaining minerals and fluoride should stay on the teeth to be absorbes. Avoid eating or drinking for at least 30 minutes after application.
  • Special cases: MI Paste (no fluoride) can be used even in very young children (ask your dentist), since any small swallowed amount is not dangerous. MI Paste Plus (with fluoride) should be used in children 6 years and older (or as advised) and in a pea-sized dose. Supervise children to ensure they spit out the paste.

Both pastes come in flavors (mint, melon, berry, bubblegum, etc.) to make brushing pleasant. Store at room temperature with cap on.

Side Effects and Warnings

These topical pastes are very safe. Because they are not swallowed (in normal use), systemic effects are virtually none. Possible side effects include:

  • Allergic reaction: Milk protein allergy is the main concern. Both products contain casein (milk-derived) and paraben preservatives. GC’s label warns not to use MI Paste products on anyone “with a milk protein or hydroxybenzoates allergy”. Symptoms of allergy (rash, hives, itching, facial swelling, breathing difficulty) warrant immediate discontinuation and medical attention.
  • Oral irritation: In rare cases, mild gum or palate irritation can occur. Both products are SLS-free (less irritating), but if your child complains of burning or sores, stop use and see a dentist.
  • Fluoride ingestion: MI Paste Plus contains fluoride (0.2%). Swallowing very large amounts (far more than a pea-sized dose) could cause nausea or vomiting. Keep the tube out of reach of young children and supervise brushing. If a child accidentally swallows a large quantity of MI Paste Plus, call your local poison control center or seek medical help. (MI Paste original has no fluoride and thus no such risk.)
  • No improvement: If sensitivity or white spots do not improve after several weeks of regular use, consult a dentist. Persistent pain, new cavities, or advancing decay are not solved by toothpaste alone.

Besides milk allergies, there are no drug interactions (the product isn’t systemic). However, those with renal failure or other severe mineral-balance issues should mention any calcium/phosphate supplement to their doctor, although topical use is generally safe. As with all dental products, pregnant/nursing women should inform their dentist; MI Paste (with virtually no systemic fluoride) is usually considered safe, and MI Paste Plus delivers only minimal fluoride topically.

Summary

  • MI Paste® – Tooth crème with CPP-ACP (calcium & phosphate), no fluoride. Uses: enamel remineralization, sensitivity relief, white-spot management. Safe for young kids and expectant mothers.
  • MI Paste Plus® – Same CPP-ACP base plus 0.2% NaF. Uses: remineralization and cavity prevention. Recommended for older children/adults with sensitivity, after whitening, or high cavity risk. Use cautiously in young children (pea-sized dose, supervised) due to fluoride.

Both are not medicines or antibiotics—they are preventive dental aids. Use as directed by a dentist or the product instructions. Do not substitute these pastes for professional dental treatment when cavities are present.

People Also Searched For

Mi Paste and MI Paste Plus by GC America Mi Paste and MI Paste Plus to Oral Health Mi Paste and MI Paste Plus to Mi Paste Plus Mi Paste and MI Paste Plus to Dry Mouth Mi Paste and MI Paste Plus to Recaldent Mi Paste and MI Paste Plus to Fluoride Toothpaste Mi Paste and MI Paste Plus to tooth enamel Mi Paste and MI Paste Plus to 10 Pack Mi Paste and MI Paste Plus to Mi Paste One Mi Paste and MI Paste Plus to Anti-cavity Toothpaste

MI Paste and MI Paste Plus

MI Paste® is a topical dental cream (by GC America) formulated to strengthen tooth enamel. Mi paste contains a milk-derived protein complex called CPP-ACP (marketed as “Recaldent”) which slowly releases bioavailable calcium and phosphate onto tooth surfaces. In other words, MI Paste provides the same mineral building blocks (calcium, phosphate, and optionally fluoride in the “Plus” version) that healthy saliva supplies. By delivering these minerals directly, MI Paste helps rebuild (remineralize) early tooth decay (such as white spot lesions) and harden enamel. This remineralization effect can also make teeth less sensitive, since it helps “fill in” microscopic defects in the enamel. (The manufacturer advertises it as the first topical crème that releases Ca/P for treating non-cavitated demineralization.

Composition & Mechanism

  • MI Paste® (original): Contains Recaldent (CPP-ACP) derived from milk. The CPP (casein phosphopeptides) molecules stabilize amorphous calcium phosphate (ACP) and adhere to tooth surfaces and plaque, delivering calcium and phosphate ions where saliva flow is low or teeth are demineralized. This remineralizes early “white-spot” lesions and can help soothe dentin hypersensitivity. Importantly, it does not contain fluoride, making it safe for young children (even under 6) and pregnant women when fluoride use may be a concern.

  • MI Paste Plus®: Everything in MI Paste plus 0.2% sodium fluoride (anti-cavity agent). The fluoride works with the delivered calcium and phosphate to form fluorapatite, which is more resistant to acid. Thus MI Paste Plus not only rebuilds enamel but also provides an anticavity (anticaries) effect. The inclusion of fluoride means it is recommended for patients at higher risk of cavities, but young children should use it only under supervision (to avoid swallowing excess fluoride).

GC America notes that MI Paste and MI Paste Plus are “the first of their kind” containing milk protein and (for Plus) fluoride. They supply minerals needed when saliva is insufficient, and MI Paste Plus supplies all three ions (calcium, phosphate, fluoride) whereas the original MI Paste supplies just calcium and phosphate. Both formulas are SLS‐free (gentle on soft tissues) and have low abrasiveness.

Uses (Indications)

Both products are used as preventive care aids in situations requiring enamel strengthening and sensitivity relief:

  • Demineralization and White spots: Ideal for early (non-cavitated) caries lesions. MI Paste products deliver minerals to “treat white spot lesions and non-cavitated tooth demineralization”. Dentists often recommend them after orthodontic treatment or heavy fluoride bleaching, when enamel needs rebuilding.
  • Sensitivity relief: By depositing calcium and phosphate, CPP-ACP can occlude exposed dentin tubules. Both MI Paste and MI Paste Plus have a desensitizing effect. GC explicitly recommends MI Paste for dentin hypersensitivity and for sensitivity after cleaning or whitening, and MI Paste Plus for patients who experience tooth sensitivity (before/after whitening or professional cleaning).
  • Cavity prevention: MI Paste Plus (with fluoride) can help prevent new cavities in at-risk patients, thanks to its fluoride content. The original MI Paste (no fluoride) is not a substitute for anticavity treatments, so it’s mainly used when fluoride use must be limited (e.g. very young children) or as an adjunct for remineralization.
  • Dry mouth and erosion: Both products are useful when saliva is low (xerostomia) or diets are acidic. They help neutralize acid pH and supply lacking minerals, protecting against erosion and decay.
  • General oral maintenance: Many users with disc treatments or crowns use MI Paste to keep enamel strong. MI Paste Plus, being anticavity, is recommended as part of preventive regimens (e.g. “ongoing dental health program” for adults, seniors).

Note: MI Paste products do not treat active cavities that already require drilling and filling—they are preventive. They also have no effect on viruses or systemic conditions.

How to Use

MI Paste and MI Paste Plus are used like a toothpaste/crème, usually after regular brushing with a normal fluoride toothpaste (to maximize benefit).

  • Frequency: Apply twice daily (morning and night) or as instructed by your dentist.
  • Application: Squeeze a pea-sized amount onto a clean finger or onto a soft toothbrush. Spread or brush it onto all tooth surfaces. (Some people also use custom trays to hold it on teeth if recommended.)
  • Dwell time: Leave it on for about 3 minutes. Spit out the excess paste. Do not rinse with water immediately—the remaining minerals and fluoride should stay on the teeth to be absorbes. Avoid eating or drinking for at least 30 minutes after application.
  • Special cases: MI Paste (no fluoride) can be used even in very young children (ask your dentist), since any small swallowed amount is not dangerous. MI Paste Plus (with fluoride) should be used in children 6 years and older (or as advised) and in a pea-sized dose. Supervise children to ensure they spit out the paste.

Both pastes come in flavors (mint, melon, berry, bubblegum, etc.) to make brushing pleasant. Store at room temperature with cap on.

Side Effects and Warnings

These topical pastes are very safe. Because they are not swallowed (in normal use), systemic effects are virtually none. Possible side effects include:

  • Allergic reaction: Milk protein allergy is the main concern. Both products contain casein (milk-derived) and paraben preservatives. GC’s label warns not to use MI Paste products on anyone “with a milk protein or hydroxybenzoates allergy”. Symptoms of allergy (rash, hives, itching, facial swelling, breathing difficulty) warrant immediate discontinuation and medical attention.
  • Oral irritation: In rare cases, mild gum or palate irritation can occur. Both products are SLS-free (less irritating), but if your child complains of burning or sores, stop use and see a dentist.
  • Fluoride ingestion: MI Paste Plus contains fluoride (0.2%). Swallowing very large amounts (far more than a pea-sized dose) could cause nausea or vomiting. Keep the tube out of reach of young children and supervise brushing. If a child accidentally swallows a large quantity of MI Paste Plus, call your local poison control center or seek medical help. (MI Paste original has no fluoride and thus no such risk.)
  • No improvement: If sensitivity or white spots do not improve after several weeks of regular use, consult a dentist. Persistent pain, new cavities, or advancing decay are not solved by toothpaste alone.

Besides milk allergies, there are no drug interactions (the product isn’t systemic). However, those with renal failure or other severe mineral-balance issues should mention any calcium/phosphate supplement to their doctor, although topical use is generally safe. As with all dental products, pregnant/nursing women should inform their dentist; MI Paste (with virtually no systemic fluoride) is usually considered safe, and MI Paste Plus delivers only minimal fluoride topically.

Summary

  • MI Paste® – Tooth crème with CPP-ACP (calcium & phosphate), no fluoride. Uses: enamel remineralization, sensitivity relief, white-spot management. Safe for young kids and expectant mothers.
  • MI Paste Plus® – Same CPP-ACP base plus 0.2% NaF. Uses: remineralization and cavity prevention. Recommended for older children/adults with sensitivity, after whitening, or high cavity risk. Use cautiously in young children (pea-sized dose, supervised) due to fluoride.

Both are not medicines or antibiotics—they are preventive dental aids. Use as directed by a dentist or the product instructions. Do not substitute these pastes for professional dental treatment when cavities are present.

How Mi Paste Works
Mi Paste Uses
Mi Paste Precautions
Directions How to use Mi paste
Active Ingredients
Mi Paste Types & Flavors

How Mi Paste Works

The key ingredient, CPP-ACP, is a casein (milk) phosphopeptide that binds calcium and phosphate ions. This sticky complex adheres to plaque, tooth pellicle and mucosa, creating a local reservoir of minerals. When applied (for example, after brushing or between meals), it shifts the tooth surface environment toward supersaturation with Ca/P. The result is a net gain of mineral in weakened spots – essentially repairing (remineralizing) enamel that has begun to dissolve, rather than drilling “holes.” Because of this mechanism, MI Paste is also used to relieve dentin hypersensitivity: the mineral coating it leaves can occlude (cover) exposed dentin tubules. (A fluoride-containing version, MI Paste Plus, adds 900 ppm fluoride for extra cavity prevention.

Uses

Dentists recommend MI Paste (and MI Paste Plus) in situations where extra enamel protection is needed. For example, it is commonly used to:

  • Remineralize early decay (white spots): MI Paste is specially indicated for “white spot” lesions and other early demineralization. It supplies the calcium and phosphate needed to rebuild these subsurface lesions.
  • Relieve sensitive teeth: It provides a protective coating that reduces tooth sensitivity. Studies and clinicians report that MI Paste promptly relieves sensitivity and can be applied before/after whitening or professional cleaning to minimize post-treatment pain.
  • Support dry mouths and high-risk patients: MI Paste does not irritate dry mouths so it is safe for patients with low saliva (xerostomia) or those on acidic diets. It is also used for orthodontic patients (to prevent decalcification around brackets) and for anyone needing extra fluoride/mineral (some products in the line are labeled for kids, pregnant women, etc., reflecting these uses.

 Mi Paste Precautions

MI Paste is very safe for most people, as it is essentially a high-strength mineral toothpaste. However, because the CPP-ACP protein is derived from milk casein, it should not be used by anyone with a milk (casein) protein allergy or a benzoate preservative allergy. Aside from that, it has no drug-like side effects. It is not intended for swallowing – patients typically spit it out or place it on their teeth for several minutes and then rinse. Used as directed (usually after toothbrushing, once or twice daily), MI Paste is a well-tolerated way to boost enamel strength and reduce dental sensitivity.

Diections for Mi Paste.

  1. Apply a pea-sized amount to clean teeth using a finger, cotton swab, or custom tray.
  2. Spread evenly over tooth surfaces or targeted sensitive/white spot areas.
  3. Leave undisturbed for 3–5 minutes (do NOT rinse; allow maximum absorption).
  4. Spit, do not swallow. Avoid eating/drinking for 30 minutes after application.
  5. Use daily as part of your oral hygiene routine, or as recommended by your dentist.

Active Ingredients

  • MI Paste: CPP-ACP (Casein Phosphopeptide-Amorphous Calcium Phosphate, Recaldent™)
  • MI Paste Plus: CPP-ACP (Recaldent™) + Sodium Fluoride (900 ppm fluoride ion)

Note: Contains milk-derived ingredients. Do not use if allergic to milk protein (casein/CPP).

Types:

  • MI Paste (No Fluoride): Ideal for patients wanting fluoride-free remineralization therapy or with fluoride sensitivity/allergy.
  • MI Paste Plus (With Fluoride): Enhanced with 900ppm sodium fluoride for extra-strength remineralization and cavity defense.

Popular Flavors and Types

MI Paste & MI Paste Plus are available in a variety of delicious, kid- and adult-friendly flavors:

  • Strawberry
  • Melon
  • Vanilla
  • Mint
  • Tutti-Frutti

Get Notified When Back in Stock