Hepatitis B Vaccine Recombivax HB Adult Dialysis Vaccine 40 mcg/1 mL Single-dose Vial **Refrigerated Item**
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Hepatitis B Vaccine Recombivax HB® Adult Dialysis Vaccine 40 mcg/1 mL Single-dose Vial (Preservative Free).
RECOMBIVAX HB is indicated for prevention of infection caused by all known subtypes of hepatitis B virus.
RECOMBIVAX HB is approved for use in individuals of all ages.
RECOMBIVAX HB Dialysis Formulation is approved for use in adult predialysis and dialysis patients 18 years of age and older.
The vaccination regimen for RECOMBIVAX HB for persons from birth through 19 years of age consists of a series of 3 doses (0.5 mL each) given on a 0-, 1-, and 6-month schedule.
The vaccination regimen for RECOMBIVAX HB for adolescents 11 through 15 years of age consists of a series of 3 doses (0.5 mL each) given on a 0-, 1-, and 6-month schedule, or a series of 2 doses (1.0 mL each) on a 0- and 4- to 6-month schedule.
The vaccination regimen for RECOMBIVAX HB for persons 20 years of age and older consists of a series of 3 doses (1.0 mL each) given on a 0-, 1-, and 6-month schedule.
The deltoid muscle is the preferred site for intramuscular injection for adults, adolescents, and children 1 year of age and older whose deltoid is large enough for intramuscular injection. The anterolateral aspect of the thigh is the preferred site for intramuscular injection for infants younger than 1 year of age. RECOMBIVAX HB should not be administered in the gluteal region, as injections given in the buttocks have resulted in lower seroconversion rates than expected. Consider subcutaneous administration only in persons who are at risk of hemorrhage following intramuscular injections.
Predialysis and Dialysis Adult Patients: The vaccination regimen for RECOMBIVAX HB Dialysis Formulation for adults on predialysis and dialysis consists of a series of 3 doses (1.0 mL each) given on a 0-,1-, and 6-month schedule.
Consider a booster dose or revaccination with RECOMBIVAX HB Dialysis Formulation (blue color code) in predialysis/dialysis patients if the anti-HBs level is less than 10 mIU/mL at 1 to 2 months after the third dose.
The duration of the protective effect on RECOMBIVAX HB in healthy vaccinees is unknown at present and the need for booster doses is not yet defined.
RECOMBIVAX HB should be administered as soon as possible after being removed from refrigeration.
